3G6E2

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
49
structure length
46
Chain Sequence
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDRRNHKRRHWRRNDTDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
molecule tags Ribosome
total genus 9
structure length 46
sequence length 49
ec nomenclature
pdb deposition date 2009-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
2 PF00832 Ribosomal_L39 Ribosomal L39 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1620.10 Mainly Alpha Orthogonal Bundle Atp Synthase Epsilon Chain; Chain: I; Ribosomal protein L39e 3g6e200
3CD62 3CC42 1VQ92 3CCR2 2OTL2 3CCS2 1YJ92 1M1K3 3CCV2 1W2B1 1QVG1 3CCL2 3I562 1S722 1Q863 1VQM2 3G712 1K9M3 3CCQ2 2OTJ2 1M903 1K733 1VQ42 1VQ62 1K8A3 1VQ72 1YIT2 1VQO2 1KD13 3CC72 1VQK2 2QEX2 3CXC1 1Q813 1VQP2 3CC22 1VQ52 1QVF1 1YJN2 3CPW1 3CMA2 3CCJ2 1YI22 1N8R3 1VQL2 1YIJ2 3CCU2 1YJW2 3G6E2 1YHQ2 1Q7Y3 1JJ21 1KQS1 3OW21 3I552 3CCM2 1VQN2 3CME2 1Q823 3CCE2 1KC83 1VQ82 1NJI3 2QA42 3G4S2
chains in the Genus database with same CATH superfamily
1E79I 3CD62 3CC42 1VQ92 3CCR2 2OTL2 3CCS2 1YJ92 1M1K3 3CCV2 1W2B1 1QVG1 3CCL2 3I562 2WPDI 1S722 1VQM2 1Q863 3G712 1K9M3 3CCQ2 2OTJ2 1M903 1K733 1VQ42 1VQ62 1K8A3 1VQ72 1YIT2 1VQO2 1KD13 3CC72 1VQK2 3OFNI 2QEX2 3ZIAI 3CXC1 2V7QI 1Q813 1VQP2 3CC22 1VQ52 2XOKI 1QVF1 1YJN2 3CPW1 3CMA2 3CCJ2 1YI22 1N8R3 1VQL2 1YIJ2 2XNDI 3CCU2 1YJW2 3G6E2 1YHQ2 1Q7Y3 1JJ21 1KQS1 2WSSI 3OW21 3I552 3CCM2 1VQN2 3CME2 1Q823 3CCE2 1KC83 1VQ82 1NJI3 2QA42 3G4S2 4YXWI
chains in the Genus database with same CATH topology
3CD62 3CC42 1VQ92 3CCR2 2OTL2 3CCS2 1YJ92 1M1K3 3CCV2 1W2B1 1QVG1 3CCL2 3I562 1S722 1Q863 1VQM2 3G712 1K9M3 3CCQ2 2OTJ2 1M903 1K733 1VQ42 1VQ62 1K8A3 1VQ72 1YIT2 1VQO2 1KD13 3CC72 1VQK2 2QEX2 3CXC1 1Q813 1VQP2 3CC22 1VQ52 1QVF1 1YJN2 3CPW1 3CMA2 3CCJ2 1YI22 1N8R3 1VQL2 1YIJ2 3CCU2 1YJW2 3G6E2 1YHQ2 1Q7Y3 1JJ21 1KQS1 3OW21 3I552 3CCM2 1VQN2 3CME2 1Q823 3CCE2 1KC83 1VQ82 1NJI3 2QA42 3G4S2
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CD6 2;  3CC4 2;  1VQ9 2;  3CCR 2;  2OTL 2;  3CCS 2;  1YJ9 2;  1M1K 3;  3CCV 2;  1W2B 1;  1QVG 1;  3CCL 2;  3I56 2;  1S72 2;  1Q86 3;  1VQM 2;  3G71 2;  1K9M 3;  3CCQ 2;  2OTJ 2;  1M90 3;  1K73 3;  1VQ4 2;  1VQ6 2;  1K8A 3;  1VQ7 2;  1YIT 2;  1VQO 2;  1KD1 3;  3CC7 2;  1VQK 2;  2QEX 2;  3CXC 1;  1Q81 3;  1VQP 2;  3CC2 2;  1VQ5 2;  1QVF 1;  1YJN 2;  3CPW 1;  3CMA 2;  3CCJ 2;  1YI2 2;  1N8R 3;  1VQL 2;  1YIJ 2;  3CCU 2;  1YJW 2;  3G6E 2;  1YHQ 2;  1Q7Y 3;  1JJ2 1;  1KQS 1;  3OW2 1;  3I55 2;  3CCM 2;  1VQN 2;  3CME 2;  1Q82 3;  3CCE 2;  1KC8 3;  1VQ8 2;  1NJI 3;  2QA4 2;  3G4S 2; 
#chains in the Genus database with same CATH topology
 1E79 I;  3CD6 2;  3CC4 2;  1VQ9 2;  3CCR 2;  2OTL 2;  3CCS 2;  1YJ9 2;  1M1K 3;  3CCV 2;  1W2B 1;  1QVG 1;  3CCL 2;  3I56 2;  2WPD I;  1S72 2;  1VQM 2;  1Q86 3;  3G71 2;  1K9M 3;  3CCQ 2;  2OTJ 2;  1M90 3;  1K73 3;  1VQ4 2;  1VQ6 2;  1K8A 3;  1VQ7 2;  1YIT 2;  1VQO 2;  1KD1 3;  3CC7 2;  1VQK 2;  3OFN I;  2QEX 2;  3ZIA I;  3CXC 1;  2V7Q I;  1Q81 3;  1VQP 2;  3CC2 2;  1VQ5 2;  2XOK I;  1QVF 1;  1YJN 2;  3CPW 1;  3CMA 2;  3CCJ 2;  1YI2 2;  1N8R 3;  1VQL 2;  1YIJ 2;  2XND I;  3CCU 2;  1YJW 2;  3G6E 2;  1YHQ 2;  1Q7Y 3;  1JJ2 1;  1KQS 1;  2WSS I;  3OW2 1;  3I55 2;  3CCM 2;  1VQN 2;  3CME 2;  1Q82 3;  3CCE 2;  1KC8 3;  1VQ8 2;  1NJI 3;  2QA4 2;  3G4S 2;  4YXW I; 
#chains in the Genus database with same CATH homology
 3CD6 2;  3CC4 2;  1VQ9 2;  3CCR 2;  2OTL 2;  3CCS 2;  1YJ9 2;  1M1K 3;  3CCV 2;  1W2B 1;  1QVG 1;  3CCL 2;  3I56 2;  1S72 2;  1Q86 3;  1VQM 2;  3G71 2;  1K9M 3;  3CCQ 2;  2OTJ 2;  1M90 3;  1K73 3;  1VQ4 2;  1VQ6 2;  1K8A 3;  1VQ7 2;  1YIT 2;  1VQO 2;  1KD1 3;  3CC7 2;  1VQK 2;  2QEX 2;  3CXC 1;  1Q81 3;  1VQP 2;  3CC2 2;  1VQ5 2;  1QVF 1;  1YJN 2;  3CPW 1;  3CMA 2;  3CCJ 2;  1YI2 2;  1N8R 3;  1VQL 2;  1YIJ 2;  3CCU 2;  1YJW 2;  3G6E 2;  1YHQ 2;  1Q7Y 3;  1JJ2 1;  1KQS 1;  3OW2 1;  3I55 2;  3CCM 2;  1VQN 2;  3CME 2;  1Q82 3;  3CCE 2;  1KC8 3;  1VQ8 2;  1NJI 3;  2QA4 2;  3G4S 2; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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