3G6EM

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
194
structure length
194
Chain Sequence
ARSAYSYIRDAWKNPGDGQLAELQWQRQQEWRNEGAVERIERPTRLDKARSQGYKAKQGVIVARVSVRKGSARKRRHKAGRRSKRQGVTRITRRKDIQRVAEERASRTFPNLRVLNSYSVGQDGRQKWHEVILIDPNHPAIQNDDDLSWICADDQADRVFRGLTGAGRRNRGLSGKGKGSEKTRPSLRSNGGKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 55
structure length 194
sequence length 194
ec nomenclature
pdb deposition date 2009-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00827 Ribosomal_L15e Ribosomal L15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1120.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal protein L15e Ribosomal protein l15e 3g6eM00
3CMEM 1QVGL 3CCSM 1YHQM 3CXCL 3CC4M 1VQ7M 1VQKM 3CCMM 3CCJM 1W2BL 3CC2M 3G71M 1VQ6M 3CCRM 3I56M 2OTLM 3CCUM 1YI2M 1M90N 1YJWM 1KD1N 3G6EM 1S72M 1Q81N 1VQPM 1YIJM 1JJ2L 1Q86N 1VQNM 2OTJM 3CC7M 3CMAM 1VQ9M 1M1KN 3I55M 3G4SM 3CCQM 1YITM 1K8AN 3CPWL 1VQ5M 1VQLM 1K9MN 1YJ9M 1K73N 3CCLM 2QEXM 1KC8N 1VQ4M 1VQ8M 1QVFL 1N8RN 1VQOM 1VQMM 1NJIN 3CD6M 2QA4M 1Q82N 1YJNM 1KQSL 3CCVM 1Q7YN 3OW2L 3CCEM
chains in the Genus database with same CATH superfamily
3CMEM 1QVGL 3CCSM 1YHQM 3CXCL 3CC4M 1VQ7M 1VQKM 3CCMM 3CCJM 1W2BL 3CC2M 3G71M 1VQ6M 3CCRM 3I56M 2OTLM 3CCUM 1YI2M 1M90N 1YJWM 1KD1N 3G6EM 1S72M 1Q81N 1VQPM 1YIJM 1JJ2L 1Q86N 1VQNM 2OTJM 3CC7M 3CMAM 1VQ9M 1M1KN 3I55M 3G4SM 3CCQM 1YITM 1K8AN 3CPWL 1VQ5M 1VQLM 1K9MN 1YJ9M 1K73N 3CCLM 2QEXM 1KC8N 1VQ4M 1VQ8M 1QVFL 1N8RN 1VQOM 1VQMM 1NJIN 3CD6M 2QA4M 1Q82N 1YJNM 1KQSL 3CCVM 1Q7YN 3OW2L 3CCEM
chains in the Genus database with same CATH topology
3CMEM 1QVGL 3CCSM 1YHQM 3CXCL 3CC4M 1VQ7M 1VQKM 3CCMM 3CCJM 1W2BL 3CC2M 3G71M 1VQ6M 3CCRM 3I56M 2OTLM 3CCUM 1YI2M 1M90N 1YJWM 1KD1N 3G6EM 1S72M 1Q81N 1VQPM 1YIJM 1JJ2L 1Q86N 1VQNM 2OTJM 3CC7M 3CMAM 1VQ9M 1M1KN 3I55M 3G4SM 3CCQM 1YITM 1K8AN 3CPWL 1VQ5M 1VQLM 1K9MN 1YJ9M 1K73N 3CCLM 2QEXM 1KC8N 1VQ4M 1VQ8M 1QVFL 1N8RN 1VQOM 1VQMM 1NJIN 3CD6M 2QA4M 1Q82N 1YJNM 1KQSL 3CCVM 1Q7YN 3OW2L 3CCEM
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CME M;  1QVG L;  3CCS M;  1YHQ M;  3CXC L;  3CC4 M;  1VQ7 M;  1VQK M;  3CCM M;  3CCJ M;  1W2B L;  3CC2 M;  3G71 M;  1VQ6 M;  3CCR M;  3I56 M;  2OTL M;  3CCU M;  1YI2 M;  1M90 N;  1YJW M;  1KD1 N;  3G6E M;  1S72 M;  1Q81 N;  1VQP M;  1YIJ M;  1JJ2 L;  1Q86 N;  1VQN M;  2OTJ M;  3CC7 M;  3CMA M;  1VQ9 M;  1M1K N;  3I55 M;  3G4S M;  3CCQ M;  1YIT M;  1K8A N;  3CPW L;  1VQ5 M;  1VQL M;  1K9M N;  1YJ9 M;  1K73 N;  3CCL M;  2QEX M;  1KC8 N;  1VQ4 M;  1VQ8 M;  1QVF L;  1N8R N;  1VQO M;  1VQM M;  1NJI N;  3CD6 M;  2QA4 M;  1Q82 N;  1YJN M;  1KQS L;  3CCV M;  1Q7Y N;  3OW2 L;  3CCE M; 
#chains in the Genus database with same CATH topology
 3CME M;  1QVG L;  3CCS M;  1YHQ M;  3CXC L;  3CC4 M;  1VQ7 M;  1VQK M;  3CCM M;  3CCJ M;  1W2B L;  3CC2 M;  3G71 M;  1VQ6 M;  3CCR M;  3I56 M;  2OTL M;  3CCU M;  1YI2 M;  1M90 N;  1YJW M;  1KD1 N;  3G6E M;  1S72 M;  1Q81 N;  1VQP M;  1YIJ M;  1JJ2 L;  1Q86 N;  1VQN M;  2OTJ M;  3CC7 M;  3CMA M;  1VQ9 M;  1M1K N;  3I55 M;  3G4S M;  3CCQ M;  1YIT M;  1K8A N;  3CPW L;  1VQ5 M;  1VQL M;  1K9M N;  1YJ9 M;  1K73 N;  3CCL M;  2QEX M;  1KC8 N;  1VQ4 M;  1VQ8 M;  1QVF L;  1N8R N;  1VQO M;  1VQM M;  1NJI N;  3CD6 M;  2QA4 M;  1Q82 N;  1YJN M;  1KQS L;  3CCV M;  1Q7Y N;  3OW2 L;  3CCE M; 
#chains in the Genus database with same CATH homology
 3CME M;  1QVG L;  3CCS M;  1YHQ M;  3CXC L;  3CC4 M;  1VQ7 M;  1VQK M;  3CCM M;  3CCJ M;  1W2B L;  3CC2 M;  3G71 M;  1VQ6 M;  3CCR M;  3I56 M;  2OTL M;  3CCU M;  1YI2 M;  1M90 N;  1YJW M;  1KD1 N;  3G6E M;  1S72 M;  1Q81 N;  1VQP M;  1YIJ M;  1JJ2 L;  1Q86 N;  1VQN M;  2OTJ M;  3CC7 M;  3CMA M;  1VQ9 M;  1M1K N;  3I55 M;  3G4S M;  3CCQ M;  1YIT M;  1K8A N;  3CPW L;  1VQ5 M;  1VQL M;  1K9M N;  1YJ9 M;  1K73 N;  3CCL M;  2QEX M;  1KC8 N;  1VQ4 M;  1VQ8 M;  1QVF L;  1N8R N;  1VQO M;  1VQM M;  1NJI N;  3CD6 M;  2QA4 M;  1Q82 N;  1YJN M;  1KQS L;  3CCV M;  1Q7Y N;  3OW2 L;  3CCE M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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