3HHQ | Genus

Total Genus 21

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	21
sequence length	127
structure length	126
Chain Sequence	DKVLKIQLRSASATVPTKSATAAGYDIYASQDITIPAMGQGMVSTDISFTVPVGTYGRIAPRSGLAVKNGIQTGAGVVDRDYTGEVKVVLFNHSQRDFAIKKGDRVAQLILEKIVDDAQIVVVDSL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Saccharomyces cerevisiae
publication title	Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme. pubmed doi rcsb
molecule keywords	Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus	21
structure length	126
sequence length	127
chains with identical sequence	B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X
ec nomenclature	ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date	2009-05-15

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00692	dUTPase	dUTPase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.40.10	Mainly Beta	Distorted Sandwich	Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A	Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A	3hhqA00

2ZDCA 2D4LA 2QXXA 4GK6A 1SNFA 1RNJA 2D4NA 2HR6A 3TPYA 1F7OA 3ZF1A 3P48A 3H6XA 2D4MA 3TPSA 4DHKA 3ZF5A 3TRLA 3TS6A 2HRMA 1EU5A 3TRNA 2J4QA 3TPNA 3ARAA 3ZF2A 1F7NA 2BT1A 3EHWA 2XCDA 3TSLA 3LQWA 1XS6A 4APZ1 1F7DA 2WE0A 3I93A 3ZF3A 1DUTA 1F7KA 3T6YA 3CA9A 4AO5A 2HXBA 3C2TA 4A6AA 1MQ7A 3ZEZA 1DUPA 1DUNA 1XS4A 4GV8A 3ZF4A 3TTAA 2V9XA 2WE1A 2HQUA 3ARNA 2OKDA 5ECTA 4WRKA 2QLPA 5F9KA 5CCOA 1DUDA 3T60A 1F7PA 4GCYA 3TPWA 1PKJA 2YZJA 2BAZA 4OOQA 3TQZA 2XCEA 1DUCA 1SLHA 3ZF0A 3T64A 1VYQA 2WE3A 2Y1TA 3HZAA 4B0HA 2PC5A 2XX6A 2OL0A 3TQ4A 2XY3A 4LHRA 2OL1A 3LOJA 3HHQA 1SJNA 2HXDA 3T70A 1F7QA 1XS1A 4OOPA 1SYLA 1PKKA 3KM3A 1SEHA 4AOZA 3ECYA 3H6DA 1SM8A 3MDXA 3C3IA 1OGHA 4XJCA 3SO2A 3TQ3A 1Q5HA 1RN8A 2Y8CA 1SMCA 1SIXA 1PKHA 3F4FA 2OKBA 2J4HA 1Q5UX 3MBQA 2R9QA 5EDDA 3TP1A 4AOOA 5CCTA 3ZF6A 1EUWA 2PY4A 1F7RA 2WE2A 3GF0A 2BSYA 2OKEA 3TQ5A
chains in the Genus database with same CATH superfamily

2ZDCA 2D4LA 2QXXA 4GK6A 1SNFA 1RNJA 2D4NA 2HR6A 3TPYA 1F7OA 3ZF1A 3P48A 3H6XA 2D4MA 3TPSA 4DHKA 3ZF5A 3TRLA 3TS6A 2HRMA 1EU5A 3TRNA 2J4QA 3TPNA 3ARAA 3ZF2A 1F7NA 2BT1A 3EHWA 2XCDA 3TSLA 3LQWA 1XS6A 4APZ1 1F7DA 2WE0A 3I93A 3ZF3A 1DUTA 1F7KA 3T6YA 3CA9A 4AO5A 2HXBA 3C2TA 4A6AA 1MQ7A 3ZEZA 1DUPA 1DUNA 1XS4A 4GV8A 3ZF4A 3TTAA 2V9XA 2WE1A 2HQUA 3ARNA 2OKDA 5ECTA 4WRKA 2QLPA 5F9KA 5CCOA 1DUDA 3T60A 1F7PA 4GCYA 3TPWA 1PKJA 2YZJA 2BAZA 4OOQA 3TQZA 2XCEA 1DUCA 1SLHA 3ZF0A 3T64A 1VYQA 2WE3A 2Y1TA 3HZAA 4B0HA 2PC5A 2XX6A 2OL0A 3TQ4A 2XY3A 4LHRA 2OL1A 3LOJA 3HHQA 1SJNA 2HXDA 3T70A 1F7QA 1XS1A 4OOPA 1SYLA 1PKKA 3KM3A 1SEHA 4AOZA 3ECYA 3H6DA 1SM8A 3MDXA 3C3IA 1OGHA 4XJCA 3SO2A 3TQ3A 1Q5HA 1RN8A 2Y8CA 1SMCA 1TULA 1SIXA 1PKHA 3F4FA 2OKBA 2J4HA 1Q5UX 3MBQA 2R9QA 5EDDA 3TP1A 4AOOA 5CCTA 3ZF6A 1EUWA 2PY4A 1F7RA 2WE2A 3GF0A 2BSYA 2OKEA 3TQ5A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2ZDC A;  2D4L A;  2QXX A;  4GK6 A;  1SNF A;  1RNJ A;  2D4N A;  2HR6 A;  3TPY A;  1F7O A;  3ZF1 A;  3P48 A;  3H6X A;  2D4M A;  3TPS A;  4DHK A;  3ZF5 A;  3TRL A;  3TS6 A;  2HRM A;  1EU5 A;  3TRN A;  2J4Q A;  3TPN A;  3ARA A;  3ZF2 A;  1F7N A;  2BT1 A;  3EHW A;  2XCD A;  3TSL A;  3LQW A;  1XS6 A;  4APZ 1;  1F7D A;  2WE0 A;  3I93 A;  3ZF3 A;  1DUT A;  1F7K A;  3T6Y A;  3CA9 A;  4AO5 A;  2HXB A;  3C2T A;  4A6A A;  1MQ7 A;  3ZEZ A;  1DUP A;  1DUN A;  1XS4 A;  4GV8 A;  3ZF4 A;  3TTA A;  2V9X A;  2WE1 A;  2HQU A;  3ARN A;  2OKD A;  5ECT A;  4WRK A;  2QLP A;  5F9K A;  5CCO A;  1DUD A;  3T60 A;  1F7P A;  4GCY A;  3TPW A;  1PKJ A;  2YZJ A;  2BAZ A;  4OOQ A;  3TQZ A;  2XCE A;  1DUC A;  1SLH A;  3ZF0 A;  3T64 A;  1VYQ A;  2WE3 A;  2Y1T A;  3HZA A;  4B0H A;  2PC5 A;  2XX6 A;  2OL0 A;  3TQ4 A;  2XY3 A;  4LHR A;  2OL1 A;  3LOJ A;  3HHQ A;  1SJN A;  2HXD A;  3T70 A;  1F7Q A;  1XS1 A;  4OOP A;  1SYL A;  1PKK A;  3KM3 A;  1SEH A;  4AOZ A;  3ECY A;  3H6D A;  1SM8 A;  3MDX A;  3C3I A;  1OGH A;  4XJC A;  3SO2 A;  3TQ3 A;  1Q5H A;  1RN8 A;  2Y8C A;  1SMC A;  1SIX A;  1PKH A;  3F4F A;  2OKB A;  2J4H A;  1Q5U X;  3MBQ A;  2R9Q A;  5EDD A;  3TP1 A;  4AOO A;  5CCT A;  3ZF6 A;  1EUW A;  2PY4 A;  1F7R A;  2WE2 A;  3GF0 A;  2BSY A;  2OKE A;  3TQ5 A; 
#chains in the Genus database with same CATH topology
 2ZDC A;  2D4L A;  2QXX A;  4GK6 A;  1SNF A;  1RNJ A;  2D4N A;  2HR6 A;  3TPY A;  1F7O A;  3ZF1 A;  3P48 A;  3H6X A;  2D4M A;  3TPS A;  4DHK A;  3ZF5 A;  3TRL A;  3TS6 A;  2HRM A;  1EU5 A;  3TRN A;  2J4Q A;  3TPN A;  3ARA A;  3ZF2 A;  1F7N A;  2BT1 A;  3EHW A;  2XCD A;  3TSL A;  3LQW A;  1XS6 A;  4APZ 1;  1F7D A;  2WE0 A;  3I93 A;  3ZF3 A;  1DUT A;  1F7K A;  3T6Y A;  3CA9 A;  4AO5 A;  2HXB A;  3C2T A;  4A6A A;  1MQ7 A;  3ZEZ A;  1DUP A;  1DUN A;  1XS4 A;  4GV8 A;  3ZF4 A;  3TTA A;  2V9X A;  2WE1 A;  2HQU A;  3ARN A;  2OKD A;  5ECT A;  4WRK A;  2QLP A;  5F9K A;  5CCO A;  1DUD A;  3T60 A;  1F7P A;  4GCY A;  3TPW A;  1PKJ A;  2YZJ A;  2BAZ A;  4OOQ A;  3TQZ A;  2XCE A;  1DUC A;  1SLH A;  3ZF0 A;  3T64 A;  1VYQ A;  2WE3 A;  2Y1T A;  3HZA A;  4B0H A;  2PC5 A;  2XX6 A;  2OL0 A;  3TQ4 A;  2XY3 A;  4LHR A;  2OL1 A;  3LOJ A;  3HHQ A;  1SJN A;  2HXD A;  3T70 A;  1F7Q A;  1XS1 A;  4OOP A;  1SYL A;  1PKK A;  3KM3 A;  1SEH A;  4AOZ A;  3ECY A;  3H6D A;  1SM8 A;  3MDX A;  3C3I A;  1OGH A;  4XJC A;  3SO2 A;  3TQ3 A;  1Q5H A;  1RN8 A;  2Y8C A;  1SMC A;  1TUL A;  1SIX A;  1PKH A;  3F4F A;  2OKB A;  2J4H A;  1Q5U X;  3MBQ A;  2R9Q A;  5EDD A;  3TP1 A;  4AOO A;  5CCT A;  3ZF6 A;  1EUW A;  2PY4 A;  1F7R A;  2WE2 A;  3GF0 A;  2BSY A;  2OKE A;  3TQ5 A; 
#chains in the Genus database with same CATH homology
 2ZDC A;  2D4L A;  2QXX A;  4GK6 A;  1SNF A;  1RNJ A;  2D4N A;  2HR6 A;  3TPY A;  1F7O A;  3ZF1 A;  3P48 A;  3H6X A;  2D4M A;  3TPS A;  4DHK A;  3ZF5 A;  3TRL A;  3TS6 A;  2HRM A;  1EU5 A;  3TRN A;  2J4Q A;  3TPN A;  3ARA A;  3ZF2 A;  1F7N A;  2BT1 A;  3EHW A;  2XCD A;  3TSL A;  3LQW A;  1XS6 A;  4APZ 1;  1F7D A;  2WE0 A;  3I93 A;  3ZF3 A;  1DUT A;  1F7K A;  3T6Y A;  3CA9 A;  4AO5 A;  2HXB A;  3C2T A;  4A6A A;  1MQ7 A;  3ZEZ A;  1DUP A;  1DUN A;  1XS4 A;  4GV8 A;  3ZF4 A;  3TTA A;  2V9X A;  2WE1 A;  2HQU A;  3ARN A;  2OKD A;  5ECT A;  4WRK A;  2QLP A;  5F9K A;  5CCO A;  1DUD A;  3T60 A;  1F7P A;  4GCY A;  3TPW A;  1PKJ A;  2YZJ A;  2BAZ A;  4OOQ A;  3TQZ A;  2XCE A;  1DUC A;  1SLH A;  3ZF0 A;  3T64 A;  1VYQ A;  2WE3 A;  2Y1T A;  3HZA A;  4B0H A;  2PC5 A;  2XX6 A;  2OL0 A;  3TQ4 A;  2XY3 A;  4LHR A;  2OL1 A;  3LOJ A;  3HHQ A;  1SJN A;  2HXD A;  3T70 A;  1F7Q A;  1XS1 A;  4OOP A;  1SYL A;  1PKK A;  3KM3 A;  1SEH A;  4AOZ A;  3ECY A;  3H6D A;  1SM8 A;  3MDX A;  3C3I A;  1OGH A;  4XJC A;  3SO2 A;  3TQ3 A;  1Q5H A;  1RN8 A;  2Y8C A;  1SMC A;  1SIX A;  1PKH A;  3F4F A;  2OKB A;  2J4H A;  1Q5U X;  3MBQ A;  2R9Q A;  5EDD A;  3TP1 A;  4AOO A;  5CCT A;  3ZF6 A;  1EUW A;  2PY4 A;  1F7R A;  2WE2 A;  3GF0 A;  2BSY A;  2OKE A;  3TQ5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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3HHQA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations