3HHTA

A mutant of the nitrile hydratase from geobacillus pallidus having enhanced thermostability
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
202
structure length
200
Chain Sequence
IDPRFPHHHPRPQSFWEARAKALESLLIEKGHLSSDAIERVIKHYEHELGPMNGAKVVAKAWTDPAFKQRLLEDSETVLRELGYYGLQGEHIRVVENTDTVHNVVVCTLSYPWPLLGLPPSWYKEPAYRARVVKEPRQVLKEFGLDLPDSVEIRVWDSSSEIRFMVLPQRPEGTEGMTEEELAKLVTRDSMIGVAKIEPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The high-resolution structure of a Cobalt containing nitrile hydratase
rcsb
molecule tags Lyase
source organism Geobacillus pallidus
molecule keywords Nitrile hydratase alpha subunit
total genus 63
structure length 200
sequence length 202
ec nomenclature ec 4.2.1.84: Nitrile hydratase.
pdb deposition date 2009-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02979 NHase_alpha Nitrile hydratase, alpha chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.330.10 Alpha Beta Alpha-Beta Complex Nitrile Hydratase; Chain A Nitrile hydratase alpha /Thiocyanate hydrolase gamma 3hhtA00
1UGRA 3X28A 3A8OA 4OB3A 2D0QA 2DXCC 2ZCFA 4FM4A 2ZPHA 3A8GA 4ZGEA 3X24A 3X20A 2CYZA 2DD4C 1UGPA 2DXBC 2ZZDC 1V29A 3QYGA 3QZ9A 3A8MA 3X26A 2ZPFA 4ZGDA 3QYHA 4OB0A 3QZ5A 2ZPIA 3WVDA 2CZ7A 3QXEA 2DD5C 4OB1A 3VYGC 3VYHA 2CZ6A 3A8LA 2ZPEA 3HHTA 2QDYA 2ZPGA 3X25A 1UGQA 3A8HA 4OB2A 3WVEA 1UGSA 2CZ1A 4ZGJA 2DPPA 1IREA 2ZPBA 2CZ0A 2AHJA 1AHJA
chains in the Genus database with same CATH superfamily
1UGRA 3X28A 3A8OA 4OB3A 2D0QA 2DXCC 2ZCFA 4FM4A 2ZPHA 3A8GA 4ZGEA 3X24A 3X20A 2CYZA 2DD4C 1UGPA 2DXBC 2ZZDC 1V29A 3QYGA 3QZ9A 3A8MA 3X26A 2ZPFA 4ZGDA 3QYHA 4OB0A 3QZ5A 2ZPIA 3WVDA 2CZ7A 3QXEA 2DD5C 4OB1A 3VYGC 3VYHA 2CZ6A 3A8LA 2ZPEA 3HHTA 2QDYA 2ZPGA 3X25A 1UGQA 3A8HA 4OB2A 3WVEA 1UGSA 2CZ1A 4ZGJA 2DPPA 1IREA 2ZPBA 2CZ0A 2AHJA 1AHJA
chains in the Genus database with same CATH topology
1UGRA 3X28A 3A8OA 4OB3A 2D0QA 2DXCC 2ZCFA 4FM4A 2ZPHA 3A8GA 4ZGEA 3X24A 3X20A 2CYZA 2DD4C 1UGPA 2DXBC 2ZZDC 1V29A 3QYGA 3QZ9A 3A8MA 3X26A 2ZPFA 4ZGDA 3QYHA 4OB0A 3QZ5A 2ZPIA 3WVDA 2CZ7A 3QXEA 2DD5C 4OB1A 3VYGC 3VYHA 2CZ6A 3A8LA 2ZPEA 3HHTA 2QDYA 2ZPGA 3X25A 1UGQA 3A8HA 4OB2A 3WVEA 1UGSA 2CZ1A 4ZGJA 2DPPA 1IREA 2ZPBA 2CZ0A 2AHJA 1AHJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UGR A;  3X28 A;  3A8O A;  4OB3 A;  2D0Q A;  2DXC C;  2ZCF A;  4FM4 A;  2ZPH A;  3A8G A;  4ZGE A;  3X24 A;  3X20 A;  2CYZ A;  2DD4 C;  1UGP A;  2DXB C;  2ZZD C;  1V29 A;  3QYG A;  3QZ9 A;  3A8M A;  3X26 A;  2ZPF A;  4ZGD A;  3QYH A;  4OB0 A;  3QZ5 A;  2ZPI A;  3WVD A;  2CZ7 A;  3QXE A;  2DD5 C;  4OB1 A;  3VYG C;  3VYH A;  2CZ6 A;  3A8L A;  2ZPE A;  3HHT A;  2QDY A;  2ZPG A;  3X25 A;  1UGQ A;  3A8H A;  4OB2 A;  3WVE A;  1UGS A;  2CZ1 A;  4ZGJ A;  2DPP A;  1IRE A;  2ZPB A;  2CZ0 A;  2AHJ A;  1AHJ A; 
#chains in the Genus database with same CATH topology
 1UGR A;  3X28 A;  3A8O A;  4OB3 A;  2D0Q A;  2DXC C;  2ZCF A;  4FM4 A;  2ZPH A;  3A8G A;  4ZGE A;  3X24 A;  3X20 A;  2CYZ A;  2DD4 C;  1UGP A;  2DXB C;  2ZZD C;  1V29 A;  3QYG A;  3QZ9 A;  3A8M A;  3X26 A;  2ZPF A;  4ZGD A;  3QYH A;  4OB0 A;  3QZ5 A;  2ZPI A;  3WVD A;  2CZ7 A;  3QXE A;  2DD5 C;  4OB1 A;  3VYG C;  3VYH A;  2CZ6 A;  3A8L A;  2ZPE A;  3HHT A;  2QDY A;  2ZPG A;  3X25 A;  1UGQ A;  3A8H A;  4OB2 A;  3WVE A;  1UGS A;  2CZ1 A;  4ZGJ A;  2DPP A;  1IRE A;  2ZPB A;  2CZ0 A;  2AHJ A;  1AHJ A; 
#chains in the Genus database with same CATH homology
 1UGR A;  3X28 A;  3A8O A;  4OB3 A;  2D0Q A;  2DXC C;  2ZCF A;  4FM4 A;  2ZPH A;  3A8G A;  4ZGE A;  3X24 A;  3X20 A;  2CYZ A;  2DD4 C;  1UGP A;  2DXB C;  2ZZD C;  1V29 A;  3QYG A;  3QZ9 A;  3A8M A;  3X26 A;  2ZPF A;  4ZGD A;  3QYH A;  4OB0 A;  3QZ5 A;  2ZPI A;  3WVD A;  2CZ7 A;  3QXE A;  2DD5 C;  4OB1 A;  3VYG C;  3VYH A;  2CZ6 A;  3A8L A;  2ZPE A;  3HHT A;  2QDY A;  2ZPG A;  3X25 A;  1UGQ A;  3A8H A;  4OB2 A;  3WVE A;  1UGS A;  2CZ1 A;  4ZGJ A;  2DPP A;  1IRE A;  2ZPB A;  2CZ0 A;  2AHJ A;  1AHJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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