3HXIA

Crystal structure of schistosome eif4e complexed with m7gpppg and 4e-bp
Total Genus 52
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
183
structure length
182
Chain Sequence
EFPHPLQDSWSYYLFQFRKALDWDECLEKVATFSTIEDFWSVLTHTVRPREITYGKDLYMFKSDIMPKWEDPKNENGGRWLINVTARQDVDFLWDELLMLLIGSDWDTDEEDRQICGAVFQPRSRGSKLSVWLTSDNEEETILSIGRRIKERLELEDTIYFQPVSDQRSQTRGSDCTGKYEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural insights into parasite EIF4E binding specificity for m7G and m2,2,7G mRNA cap.
pubmed doi rcsb
molecule keywords Eukaryotic Translation Initiation 4E
molecule tags Translation
source organism Schistosoma mansoni
total genus 52
structure length 182
sequence length 183
ec nomenclature
pdb deposition date 2009-06-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.760.10 Alpha Beta 2-Layer Sandwich RNA Cap, Translation Initiation Factor Eif4e RNA Cap, Translation Initiation Factor Eif4e 3hxiA01
5EKVA 5T48A 5EI3A 5EHCA 4DUMA 2V8XA 2IDVA 4DT6A 1IPBA 4UECA 4UE8A 5ABUA 4UEDA 3HXGA 5ABVA 1EJHA 1AP8A 3AM7A 2Q4KA 3M93A 2JGBA 2W97B 4AXGA 4B6VA 5ABXA 5T47A 5ABYA 1RF8A 1IPCA 2W97A 1WKWA 4UE9A 3U7XA 2V8WA 1EJ1A 4B6UA 1L8BA 1ZTPA 2V8YA 5T46A 2IDRA 3M94A 2WMCA 4TQBA 5BXVA 5EIRA 4UEBA 4AZAA 5GW6A 4TQCA 2GPQA 1EJ4A 2JGCA 3TF2A 4UEAA 4BEAA 4TPWA 3HXIA
chains in the Genus database with same CATH superfamily
5EKVA 5T48A 5EI3A 5EHCA 4DUMA 2V8XA 2IDVA 4DT6A 1IPBA 4UECA 4UE8A 5ABUA 4UEDA 3HXGA 5ABVA 1EJHA 1AP8A 3AM7A 2Q4KA 3M93A 2JGBA 2W97B 4AXGA 4B6VA 5ABXA 5T47A 5ABYA 1RF8A 1IPCA 2W97A 1WKWA 4UE9A 3U7XA 2V8WA 1EJ1A 4B6UA 1L8BA 1ZTPA 2V8YA 5T46A 2IDRA 3M94A 2WMCA 4TQBA 5BXVA 5EIRA 4UEBA 4AZAA 5GW6A 4TQCA 2GPQA 1EJ4A 2JGCA 3TF2A 4UEAA 4BEAA 4TPWA 3HXIA
chains in the Genus database with same CATH topology
5EKVA 5T48A 5EI3A 5EHCA 4DUMA 2V8XA 2IDVA 4DT6A 1IPBA 4UECA 4UE8A 5ABUA 4UEDA 3HXGA 5ABVA 1EJHA 1AP8A 3AM7A 2Q4KA 3M93A 2JGBA 2W97B 4AXGA 4B6VA 5ABXA 5T47A 5ABYA 1RF8A 1IPCA 2W97A 1WKWA 4UE9A 3U7XA 2V8WA 1EJ1A 4B6UA 1L8BA 1ZTPA 2V8YA 5T46A 2IDRA 3M94A 2WMCA 4TQBA 5BXVA 5EIRA 4UEBA 4AZAA 5GW6A 4TQCA 2GPQA 1EJ4A 2JGCA 3TF2A 4UEAA 4BEAA 4TPWA 3HXIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EKV A;  5T48 A;  5EI3 A;  5EHC A;  4DUM A;  2V8X A;  2IDV A;  4DT6 A;  1IPB A;  4UEC A;  4UE8 A;  5ABU A;  4UED A;  3HXG A;  5ABV A;  1EJH A;  1AP8 A;  3AM7 A;  2Q4K A;  3M93 A;  2JGB A;  2W97 B;  4AXG A;  4B6V A;  5ABX A;  5T47 A;  5ABY A;  1RF8 A;  1IPC A;  2W97 A;  1WKW A;  4UE9 A;  3U7X A;  2V8W A;  1EJ1 A;  4B6U A;  1L8B A;  1ZTP A;  2V8Y A;  5T46 A;  2IDR A;  3M94 A;  2WMC A;  4TQB A;  5BXV A;  5EIR A;  4UEB A;  4AZA A;  5GW6 A;  4TQC A;  2GPQ A;  1EJ4 A;  2JGC A;  3TF2 A;  4UEA A;  4BEA A;  4TPW A;  3HXI A; 
#chains in the Genus database with same CATH topology
 5EKV A;  5T48 A;  5EI3 A;  5EHC A;  4DUM A;  2V8X A;  2IDV A;  4DT6 A;  1IPB A;  4UEC A;  4UE8 A;  5ABU A;  4UED A;  3HXG A;  5ABV A;  1EJH A;  1AP8 A;  3AM7 A;  2Q4K A;  3M93 A;  2JGB A;  2W97 B;  4AXG A;  4B6V A;  5ABX A;  5T47 A;  5ABY A;  1RF8 A;  1IPC A;  2W97 A;  1WKW A;  4UE9 A;  3U7X A;  2V8W A;  1EJ1 A;  4B6U A;  1L8B A;  1ZTP A;  2V8Y A;  5T46 A;  2IDR A;  3M94 A;  2WMC A;  4TQB A;  5BXV A;  5EIR A;  4UEB A;  4AZA A;  5GW6 A;  4TQC A;  2GPQ A;  1EJ4 A;  2JGC A;  3TF2 A;  4UEA A;  4BEA A;  4TPW A;  3HXI A; 
#chains in the Genus database with same CATH homology
 5EKV A;  5T48 A;  5EI3 A;  5EHC A;  4DUM A;  2V8X A;  2IDV A;  4DT6 A;  1IPB A;  4UEC A;  4UE8 A;  5ABU A;  4UED A;  3HXG A;  5ABV A;  1EJH A;  1AP8 A;  3AM7 A;  2Q4K A;  3M93 A;  2JGB A;  2W97 B;  4AXG A;  4B6V A;  5ABX A;  5T47 A;  5ABY A;  1RF8 A;  1IPC A;  2W97 A;  1WKW A;  4UE9 A;  3U7X A;  2V8W A;  1EJ1 A;  4B6U A;  1L8B A;  1ZTP A;  2V8Y A;  5T46 A;  2IDR A;  3M94 A;  2WMC A;  4TQB A;  5BXV A;  5EIR A;  4UEB A;  4AZA A;  5GW6 A;  4TQC A;  2GPQ A;  1EJ4 A;  2JGC A;  3TF2 A;  4UEA A;  4BEA A;  4TPW A;  3HXI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...