3HZA | Genus

Total Genus 26

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	26
sequence length	162
structure length	162
Chain Sequence	GLVPRGSHMSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGGWGSSGGHASL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Mycobacterium tuberculosis
publication title	Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase. pubmed doi rcsb
molecule keywords	Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus	26
structure length	162
sequence length	162
ec nomenclature	ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date	2009-06-23

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00692	dUTPase	dUTPase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.40.10	Mainly Beta	Distorted Sandwich	Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A	Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A	3hzaA01

3ZF4A 1OGHA 2HQUA 2HXDA 2OKDA 3TPNA 1SLHA 1F7RA 3T60A 2WE3A 4XJCA 1SIXA 1SYLA 3TSLA 3TRNA 3TQZA 4OOPA 1DUPA 2PC5A 3ZF1A 1RNJA 1RN8A 4OOQA 2BAZA 1XS6A 3ZF5A 3ZF6A 4AOOA 3ZF3A 2OKBA 1F7NA 3GF0A 1SEHA 3TS6A 3ARNA 1DUCA 1MQ7A 3TQ5A 3LQWA 4GK6A 3ARAA 2PY4A 2Y8CA 3TQ3A 2OL0A 1SNFA 3KM3A 3TP1A 1Q5UX 4A6AA 3CA9A 3HHQA 3TPSA 1PKHA 1DUNA 2QXXA 3C2TA 4APZ1 5F9KA 2OL1A 4LHRA 2D4LA 1XS1A 3C3IA 3HZAA 3MBQA 3F4FA 3TPYA 2J4QA 1PKJA 1DUDA 3TRLA 4GV8A 1F7DA 3TPWA 4WRKA 3ZF0A 2D4NA 3MDXA 3SO2A 3T64A 1SMCA 4DHKA 1F7OA 1PKKA 2R9QA 2WE2A 1SJNA 2WE0A 5CCTA 1VYQA 5EDDA 3TTAA 1SM8A 3H6XA 1F7PA 2WE1A 4GCYA 2BT1A 2YZJA 3TQ4A 3LOJA 2HRMA 5ECTA 2XY3A 4AO5A 1Q5HA 2Y1TA 2HXBA 3T70A 3ECYA 2J4HA 2ZDCA 2D4MA 2XX6A 2HR6A 5CCOA 1EU5A 2XCDA 1F7KA 1EUWA 4B0HA 2QLPA 3I93A 1DUTA 2BSYA 2OKEA 1F7QA 1XS4A 3ZEZA 2V9XA 3ZF2A 3T6YA 3EHWA 4AOZA 2XCEA 3H6DA 3P48A
chains in the Genus database with same CATH superfamily

3ZF4A 1OGHA 2HQUA 2HXDA 2OKDA 3TPNA 1SLHA 1F7RA 3T60A 2WE3A 4XJCA 1SIXA 1SYLA 3TSLA 3TRNA 3TQZA 4OOPA 1DUPA 2PC5A 3ZF1A 1RNJA 1RN8A 4OOQA 2BAZA 1XS6A 3ZF5A 3ZF6A 4AOOA 3ZF3A 2OKBA 1F7NA 3GF0A 1SEHA 3TS6A 3ARNA 1DUCA 1MQ7A 3TQ5A 3LQWA 4GK6A 3ARAA 2PY4A 2Y8CA 3TQ3A 2OL0A 1SNFA 3KM3A 3TP1A 1Q5UX 4A6AA 3CA9A 3HHQA 3TPSA 1PKHA 1DUNA 2QXXA 1TULA 3C2TA 4APZ1 5F9KA 2OL1A 4LHRA 2D4LA 1XS1A 3C3IA 3HZAA 3MBQA 3F4FA 3TPYA 2J4QA 1PKJA 1DUDA 3TRLA 4GV8A 1F7DA 3TPWA 4WRKA 3ZF0A 2D4NA 3MDXA 3SO2A 3T64A 1SMCA 4DHKA 1F7OA 1PKKA 2R9QA 2WE2A 1SJNA 2WE0A 5CCTA 1VYQA 5EDDA 3TTAA 1SM8A 3H6XA 1F7PA 2WE1A 4GCYA 2BT1A 2YZJA 3TQ4A 3LOJA 2HRMA 5ECTA 2XY3A 4AO5A 1Q5HA 2Y1TA 2HXBA 3T70A 3ECYA 2J4HA 2ZDCA 2D4MA 2XX6A 2HR6A 5CCOA 1EU5A 2XCDA 1F7KA 1EUWA 4B0HA 2QLPA 3I93A 1DUTA 2BSYA 2OKEA 1F7QA 1XS4A 3ZEZA 2V9XA 3ZF2A 3T6YA 3EHWA 4AOZA 2XCEA 3H6DA 3P48A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3ZF4 A;  1OGH A;  2HQU A;  2HXD A;  2OKD A;  3TPN A;  1SLH A;  1F7R A;  3T60 A;  2WE3 A;  4XJC A;  1SIX A;  1SYL A;  3TSL A;  3TRN A;  3TQZ A;  4OOP A;  1DUP A;  2PC5 A;  3ZF1 A;  1RNJ A;  1RN8 A;  4OOQ A;  2BAZ A;  1XS6 A;  3ZF5 A;  3ZF6 A;  4AOO A;  3ZF3 A;  2OKB A;  1F7N A;  3GF0 A;  1SEH A;  3TS6 A;  3ARN A;  1DUC A;  1MQ7 A;  3TQ5 A;  3LQW A;  4GK6 A;  3ARA A;  2PY4 A;  2Y8C A;  3TQ3 A;  2OL0 A;  1SNF A;  3KM3 A;  3TP1 A;  1Q5U X;  4A6A A;  3CA9 A;  3HHQ A;  3TPS A;  1PKH A;  1DUN A;  2QXX A;  3C2T A;  4APZ 1;  5F9K A;  2OL1 A;  4LHR A;  2D4L A;  1XS1 A;  3C3I A;  3HZA A;  3MBQ A;  3F4F A;  3TPY A;  2J4Q A;  1PKJ A;  1DUD A;  3TRL A;  4GV8 A;  1F7D A;  3TPW A;  4WRK A;  3ZF0 A;  2D4N A;  3MDX A;  3SO2 A;  3T64 A;  1SMC A;  4DHK A;  1F7O A;  1PKK A;  2R9Q A;  2WE2 A;  1SJN A;  2WE0 A;  5CCT A;  1VYQ A;  5EDD A;  3TTA A;  1SM8 A;  3H6X A;  1F7P A;  2WE1 A;  4GCY A;  2BT1 A;  2YZJ A;  3TQ4 A;  3LOJ A;  2HRM A;  5ECT A;  2XY3 A;  4AO5 A;  1Q5H A;  2Y1T A;  2HXB A;  3T70 A;  3ECY A;  2J4H A;  2ZDC A;  2D4M A;  2XX6 A;  2HR6 A;  5CCO A;  1EU5 A;  2XCD A;  1F7K A;  1EUW A;  4B0H A;  2QLP A;  3I93 A;  1DUT A;  2BSY A;  2OKE A;  1F7Q A;  1XS4 A;  3ZEZ A;  2V9X A;  3ZF2 A;  3T6Y A;  3EHW A;  4AOZ A;  2XCE A;  3H6D A;  3P48 A; 
#chains in the Genus database with same CATH topology
 3ZF4 A;  1OGH A;  2HQU A;  2HXD A;  2OKD A;  3TPN A;  1SLH A;  1F7R A;  3T60 A;  2WE3 A;  4XJC A;  1SIX A;  1SYL A;  3TSL A;  3TRN A;  3TQZ A;  4OOP A;  1DUP A;  2PC5 A;  3ZF1 A;  1RNJ A;  1RN8 A;  4OOQ A;  2BAZ A;  1XS6 A;  3ZF5 A;  3ZF6 A;  4AOO A;  3ZF3 A;  2OKB A;  1F7N A;  3GF0 A;  1SEH A;  3TS6 A;  3ARN A;  1DUC A;  1MQ7 A;  3TQ5 A;  3LQW A;  4GK6 A;  3ARA A;  2PY4 A;  2Y8C A;  3TQ3 A;  2OL0 A;  1SNF A;  3KM3 A;  3TP1 A;  1Q5U X;  4A6A A;  3CA9 A;  3HHQ A;  3TPS A;  1PKH A;  1DUN A;  2QXX A;  1TUL A;  3C2T A;  4APZ 1;  5F9K A;  2OL1 A;  4LHR A;  2D4L A;  1XS1 A;  3C3I A;  3HZA A;  3MBQ A;  3F4F A;  3TPY A;  2J4Q A;  1PKJ A;  1DUD A;  3TRL A;  4GV8 A;  1F7D A;  3TPW A;  4WRK A;  3ZF0 A;  2D4N A;  3MDX A;  3SO2 A;  3T64 A;  1SMC A;  4DHK A;  1F7O A;  1PKK A;  2R9Q A;  2WE2 A;  1SJN A;  2WE0 A;  5CCT A;  1VYQ A;  5EDD A;  3TTA A;  1SM8 A;  3H6X A;  1F7P A;  2WE1 A;  4GCY A;  2BT1 A;  2YZJ A;  3TQ4 A;  3LOJ A;  2HRM A;  5ECT A;  2XY3 A;  4AO5 A;  1Q5H A;  2Y1T A;  2HXB A;  3T70 A;  3ECY A;  2J4H A;  2ZDC A;  2D4M A;  2XX6 A;  2HR6 A;  5CCO A;  1EU5 A;  2XCD A;  1F7K A;  1EUW A;  4B0H A;  2QLP A;  3I93 A;  1DUT A;  2BSY A;  2OKE A;  1F7Q A;  1XS4 A;  3ZEZ A;  2V9X A;  3ZF2 A;  3T6Y A;  3EHW A;  4AOZ A;  2XCE A;  3H6D A;  3P48 A; 
#chains in the Genus database with same CATH homology
 3ZF4 A;  1OGH A;  2HQU A;  2HXD A;  2OKD A;  3TPN A;  1SLH A;  1F7R A;  3T60 A;  2WE3 A;  4XJC A;  1SIX A;  1SYL A;  3TSL A;  3TRN A;  3TQZ A;  4OOP A;  1DUP A;  2PC5 A;  3ZF1 A;  1RNJ A;  1RN8 A;  4OOQ A;  2BAZ A;  1XS6 A;  3ZF5 A;  3ZF6 A;  4AOO A;  3ZF3 A;  2OKB A;  1F7N A;  3GF0 A;  1SEH A;  3TS6 A;  3ARN A;  1DUC A;  1MQ7 A;  3TQ5 A;  3LQW A;  4GK6 A;  3ARA A;  2PY4 A;  2Y8C A;  3TQ3 A;  2OL0 A;  1SNF A;  3KM3 A;  3TP1 A;  1Q5U X;  4A6A A;  3CA9 A;  3HHQ A;  3TPS A;  1PKH A;  1DUN A;  2QXX A;  3C2T A;  4APZ 1;  5F9K A;  2OL1 A;  4LHR A;  2D4L A;  1XS1 A;  3C3I A;  3HZA A;  3MBQ A;  3F4F A;  3TPY A;  2J4Q A;  1PKJ A;  1DUD A;  3TRL A;  4GV8 A;  1F7D A;  3TPW A;  4WRK A;  3ZF0 A;  2D4N A;  3MDX A;  3SO2 A;  3T64 A;  1SMC A;  4DHK A;  1F7O A;  1PKK A;  2R9Q A;  2WE2 A;  1SJN A;  2WE0 A;  5CCT A;  1VYQ A;  5EDD A;  3TTA A;  1SM8 A;  3H6X A;  1F7P A;  2WE1 A;  4GCY A;  2BT1 A;  2YZJ A;  3TQ4 A;  3LOJ A;  2HRM A;  5ECT A;  2XY3 A;  4AO5 A;  1Q5H A;  2Y1T A;  2HXB A;  3T70 A;  3ECY A;  2J4H A;  2ZDC A;  2D4M A;  2XX6 A;  2HR6 A;  5CCO A;  1EU5 A;  2XCD A;  1F7K A;  1EUW A;  4B0H A;  2QLP A;  3I93 A;  1DUT A;  2BSY A;  2OKE A;  1F7Q A;  1XS4 A;  3ZEZ A;  2V9X A;  3ZF2 A;  3T6Y A;  3EHW A;  4AOZ A;  2XCE A;  3H6D A;  3P48 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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3HZAA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations