3I93A

Crystal structure of mycobacterium tuberculosis dutpase stop138t mutant
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
144
structure length
140
Chain Sequence
SSGLVPRSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 21
structure length 140
sequence length 144
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2009-07-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 3i93A01
1XS1A 2WE0A 2D4MA 1SM8A 3ZF0A 1DUNA 2Y8CA 1EU5A 2HR6A 1VYQA 2D4NA 1F7NA 3TQ3A 4AO5A 1PKJA 4GCYA 3ECYA 2XCEA 1DUPA 3P48A 3TTAA 2ZDCA 1MQ7A 3EHWA 2PY4A 4B0HA 1F7QA 2YZJA 3HHQA 3H6DA 1SLHA 2D4LA 2J4QA 3TP1A 2OKEA 3F4FA 3H6XA 2WE2A 1DUTA 2XY3A 1PKKA 1Q5HA 4APZ1 1F7DA 3TQ5A 3ARNA 4OOQA 1PKHA 3T6YA 1SMCA 3TPSA 2J4HA 3CA9A 4GK6A 3LOJA 2Y1TA 3TRLA 2XX6A 1SEHA 5CCOA 1SNFA 1SYLA 2HRMA 2QLPA 2OKDA 1DUDA 2WE1A 2QXXA 1XS4A 5F9KA 4LHRA 3ZF1A 5EDDA 4WRKA 1OGHA 3TPNA 1F7OA 4DHKA 2OKBA 2BSYA 3ZF5A 2R9QA 2HQUA 4OOPA 3GF0A 5CCTA 2HXDA 1F7PA 3C3IA 3ZF2A 1EUWA 2HXBA 3T64A 3T60A 3TS6A 3KM3A 4GV8A 3MDXA 3T70A 2BT1A 4AOZA 4AOOA 3SO2A 3ZEZA 1SIXA 3I93A 2PC5A 3ZF4A 3TPYA 1XS6A 2WE3A 2OL0A 3TPWA 1DUCA 2BAZA 1RN8A 3HZAA 3MBQA 3TQ4A 2V9XA 1Q5UX 1F7RA 3ARAA 3TRNA 1RNJA 4A6AA 3TSLA 4XJCA 3C2TA 1SJNA 2XCDA 5ECTA 3LQWA 3TQZA 3ZF6A 1F7KA 2OL1A 3ZF3A
chains in the Genus database with same CATH superfamily
1XS1A 2WE0A 2D4MA 1SM8A 3ZF0A 1DUNA 2Y8CA 1EU5A 2HR6A 1VYQA 2D4NA 1F7NA 3TQ3A 4AO5A 1PKJA 4GCYA 3ECYA 2XCEA 1DUPA 3P48A 3TTAA 2ZDCA 1MQ7A 3EHWA 2PY4A 4B0HA 1F7QA 2YZJA 3HHQA 3H6DA 1SLHA 2D4LA 2J4QA 3TP1A 2OKEA 3F4FA 3H6XA 2WE2A 1DUTA 2XY3A 1PKKA 1Q5HA 4APZ1 1F7DA 3TQ5A 3ARNA 4OOQA 1PKHA 3T6YA 1SMCA 3TPSA 2J4HA 3CA9A 4GK6A 3LOJA 2Y1TA 3TRLA 2XX6A 1SEHA 5CCOA 1SNFA 1SYLA 2HRMA 2QLPA 2OKDA 1DUDA 2WE1A 2QXXA 1XS4A 5F9KA 4LHRA 3ZF1A 5EDDA 4WRKA 1OGHA 3TPNA 1F7OA 4DHKA 2OKBA 2BSYA 3ZF5A 2R9QA 2HQUA 4OOPA 3GF0A 5CCTA 2HXDA 1F7PA 3C3IA 3ZF2A 1EUWA 2HXBA 3T64A 3T60A 3TS6A 3KM3A 4GV8A 3MDXA 3T70A 2BT1A 4AOZA 4AOOA 3SO2A 3ZEZA 1SIXA 3I93A 2PC5A 3ZF4A 3TPYA 1XS6A 2WE3A 2OL0A 3TPWA 1TULA 1DUCA 2BAZA 1RN8A 3HZAA 3MBQA 3TQ4A 2V9XA 1Q5UX 1F7RA 3ARAA 3TRNA 1RNJA 4A6AA 3TSLA 4XJCA 3C2TA 1SJNA 2XCDA 5ECTA 3LQWA 3TQZA 3ZF6A 1F7KA 2OL1A 3ZF3A
chains in the Genus database with same CATH topology
1XS1A 2WE0A 2D4MA 1SM8A 3ZF0A 1DUNA 2Y8CA 1EU5A 2HR6A 1VYQA 2D4NA 1F7NA 3TQ3A 4AO5A 1PKJA 4GCYA 3ECYA 2XCEA 1DUPA 3P48A 3TTAA 2ZDCA 1MQ7A 3EHWA 2PY4A 4B0HA 1F7QA 2YZJA 3HHQA 3H6DA 1SLHA 2D4LA 2J4QA 3TP1A 2OKEA 3F4FA 3H6XA 2WE2A 1DUTA 2XY3A 1PKKA 1Q5HA 4APZ1 1F7DA 3TQ5A 3ARNA 4OOQA 1PKHA 3T6YA 1SMCA 3TPSA 2J4HA 3CA9A 4GK6A 3LOJA 2Y1TA 3TRLA 2XX6A 1SEHA 5CCOA 1SNFA 1SYLA 2HRMA 2QLPA 2OKDA 1DUDA 2WE1A 2QXXA 1XS4A 5F9KA 4LHRA 3ZF1A 5EDDA 4WRKA 1OGHA 3TPNA 1F7OA 4DHKA 2OKBA 2BSYA 3ZF5A 2R9QA 2HQUA 4OOPA 3GF0A 5CCTA 2HXDA 1F7PA 3C3IA 3ZF2A 1EUWA 2HXBA 3T64A 3T60A 3TS6A 3KM3A 4GV8A 3MDXA 3T70A 2BT1A 4AOZA 4AOOA 3SO2A 3ZEZA 1SIXA 3I93A 2PC5A 3ZF4A 3TPYA 1XS6A 2WE3A 2OL0A 3TPWA 1DUCA 2BAZA 1RN8A 3HZAA 3MBQA 3TQ4A 2V9XA 1Q5UX 1F7RA 3ARAA 3TRNA 1RNJA 4A6AA 3TSLA 4XJCA 3C2TA 1SJNA 2XCDA 5ECTA 3LQWA 3TQZA 3ZF6A 1F7KA 2OL1A 3ZF3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XS1 A;  2WE0 A;  2D4M A;  1SM8 A;  3ZF0 A;  1DUN A;  2Y8C A;  1EU5 A;  2HR6 A;  1VYQ A;  2D4N A;  1F7N A;  3TQ3 A;  4AO5 A;  1PKJ A;  4GCY A;  3ECY A;  2XCE A;  1DUP A;  3P48 A;  3TTA A;  2ZDC A;  1MQ7 A;  3EHW A;  2PY4 A;  4B0H A;  1F7Q A;  2YZJ A;  3HHQ A;  3H6D A;  1SLH A;  2D4L A;  2J4Q A;  3TP1 A;  2OKE A;  3F4F A;  3H6X A;  2WE2 A;  1DUT A;  2XY3 A;  1PKK A;  1Q5H A;  4APZ 1;  1F7D A;  3TQ5 A;  3ARN A;  4OOQ A;  1PKH A;  3T6Y A;  1SMC A;  3TPS A;  2J4H A;  3CA9 A;  4GK6 A;  3LOJ A;  2Y1T A;  3TRL A;  2XX6 A;  1SEH A;  5CCO A;  1SNF A;  1SYL A;  2HRM A;  2QLP A;  2OKD A;  1DUD A;  2WE1 A;  2QXX A;  1XS4 A;  5F9K A;  4LHR A;  3ZF1 A;  5EDD A;  4WRK A;  1OGH A;  3TPN A;  1F7O A;  4DHK A;  2OKB A;  2BSY A;  3ZF5 A;  2R9Q A;  2HQU A;  4OOP A;  3GF0 A;  5CCT A;  2HXD A;  1F7P A;  3C3I A;  3ZF2 A;  1EUW A;  2HXB A;  3T64 A;  3T60 A;  3TS6 A;  3KM3 A;  4GV8 A;  3MDX A;  3T70 A;  2BT1 A;  4AOZ A;  4AOO A;  3SO2 A;  3ZEZ A;  1SIX A;  3I93 A;  2PC5 A;  3ZF4 A;  3TPY A;  1XS6 A;  2WE3 A;  2OL0 A;  3TPW A;  1DUC A;  2BAZ A;  1RN8 A;  3HZA A;  3MBQ A;  3TQ4 A;  2V9X A;  1Q5U X;  1F7R A;  3ARA A;  3TRN A;  1RNJ A;  4A6A A;  3TSL A;  4XJC A;  3C2T A;  1SJN A;  2XCD A;  5ECT A;  3LQW A;  3TQZ A;  3ZF6 A;  1F7K A;  2OL1 A;  3ZF3 A; 
#chains in the Genus database with same CATH topology
 1XS1 A;  2WE0 A;  2D4M A;  1SM8 A;  3ZF0 A;  1DUN A;  2Y8C A;  1EU5 A;  2HR6 A;  1VYQ A;  2D4N A;  1F7N A;  3TQ3 A;  4AO5 A;  1PKJ A;  4GCY A;  3ECY A;  2XCE A;  1DUP A;  3P48 A;  3TTA A;  2ZDC A;  1MQ7 A;  3EHW A;  2PY4 A;  4B0H A;  1F7Q A;  2YZJ A;  3HHQ A;  3H6D A;  1SLH A;  2D4L A;  2J4Q A;  3TP1 A;  2OKE A;  3F4F A;  3H6X A;  2WE2 A;  1DUT A;  2XY3 A;  1PKK A;  1Q5H A;  4APZ 1;  1F7D A;  3TQ5 A;  3ARN A;  4OOQ A;  1PKH A;  3T6Y A;  1SMC A;  3TPS A;  2J4H A;  3CA9 A;  4GK6 A;  3LOJ A;  2Y1T A;  3TRL A;  2XX6 A;  1SEH A;  5CCO A;  1SNF A;  1SYL A;  2HRM A;  2QLP A;  2OKD A;  1DUD A;  2WE1 A;  2QXX A;  1XS4 A;  5F9K A;  4LHR A;  3ZF1 A;  5EDD A;  4WRK A;  1OGH A;  3TPN A;  1F7O A;  4DHK A;  2OKB A;  2BSY A;  3ZF5 A;  2R9Q A;  2HQU A;  4OOP A;  3GF0 A;  5CCT A;  2HXD A;  1F7P A;  3C3I A;  3ZF2 A;  1EUW A;  2HXB A;  3T64 A;  3T60 A;  3TS6 A;  3KM3 A;  4GV8 A;  3MDX A;  3T70 A;  2BT1 A;  4AOZ A;  4AOO A;  3SO2 A;  3ZEZ A;  1SIX A;  3I93 A;  2PC5 A;  3ZF4 A;  3TPY A;  1XS6 A;  2WE3 A;  2OL0 A;  3TPW A;  1TUL A;  1DUC A;  2BAZ A;  1RN8 A;  3HZA A;  3MBQ A;  3TQ4 A;  2V9X A;  1Q5U X;  1F7R A;  3ARA A;  3TRN A;  1RNJ A;  4A6A A;  3TSL A;  4XJC A;  3C2T A;  1SJN A;  2XCD A;  5ECT A;  3LQW A;  3TQZ A;  3ZF6 A;  1F7K A;  2OL1 A;  3ZF3 A; 
#chains in the Genus database with same CATH homology
 1XS1 A;  2WE0 A;  2D4M A;  1SM8 A;  3ZF0 A;  1DUN A;  2Y8C A;  1EU5 A;  2HR6 A;  1VYQ A;  2D4N A;  1F7N A;  3TQ3 A;  4AO5 A;  1PKJ A;  4GCY A;  3ECY A;  2XCE A;  1DUP A;  3P48 A;  3TTA A;  2ZDC A;  1MQ7 A;  3EHW A;  2PY4 A;  4B0H A;  1F7Q A;  2YZJ A;  3HHQ A;  3H6D A;  1SLH A;  2D4L A;  2J4Q A;  3TP1 A;  2OKE A;  3F4F A;  3H6X A;  2WE2 A;  1DUT A;  2XY3 A;  1PKK A;  1Q5H A;  4APZ 1;  1F7D A;  3TQ5 A;  3ARN A;  4OOQ A;  1PKH A;  3T6Y A;  1SMC A;  3TPS A;  2J4H A;  3CA9 A;  4GK6 A;  3LOJ A;  2Y1T A;  3TRL A;  2XX6 A;  1SEH A;  5CCO A;  1SNF A;  1SYL A;  2HRM A;  2QLP A;  2OKD A;  1DUD A;  2WE1 A;  2QXX A;  1XS4 A;  5F9K A;  4LHR A;  3ZF1 A;  5EDD A;  4WRK A;  1OGH A;  3TPN A;  1F7O A;  4DHK A;  2OKB A;  2BSY A;  3ZF5 A;  2R9Q A;  2HQU A;  4OOP A;  3GF0 A;  5CCT A;  2HXD A;  1F7P A;  3C3I A;  3ZF2 A;  1EUW A;  2HXB A;  3T64 A;  3T60 A;  3TS6 A;  3KM3 A;  4GV8 A;  3MDX A;  3T70 A;  2BT1 A;  4AOZ A;  4AOO A;  3SO2 A;  3ZEZ A;  1SIX A;  3I93 A;  2PC5 A;  3ZF4 A;  3TPY A;  1XS6 A;  2WE3 A;  2OL0 A;  3TPW A;  1DUC A;  2BAZ A;  1RN8 A;  3HZA A;  3MBQ A;  3TQ4 A;  2V9X A;  1Q5U X;  1F7R A;  3ARA A;  3TRN A;  1RNJ A;  4A6A A;  3TSL A;  4XJC A;  3C2T A;  1SJN A;  2XCD A;  5ECT A;  3LQW A;  3TQZ A;  3ZF6 A;  1F7K A;  2OL1 A;  3ZF3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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