3NGBA

Crystal structure of broadly and potently neutralizing antibody vrc01 in complex with hiv-1 gp120
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
353
structure length
349
Chain Sequence
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNSGGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEFFYCNTTQLFNNTCIGNETMKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords Envelope glycoprotein gp160
total genus 87
structure length 349
sequence length 353
chains with identical sequence D, G, I
ec nomenclature
pdb deposition date 2010-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 3ngbA01
3SE9G 1YYLG 4DKQA 4OLUG 4YDJG 4OLWG 4OM0G 4P9HG 4RFOG 4JZZA 4LSTG 5TE7G 4YDLA 4JB9G 2NY2A 1YYMG 4OLYG 5F4RA 5CAYG 4OM1G 4OLZG 5I9QA 4LSRG 5TE4G 2NY5G 2BF1A 4YDKG 3TGQA 3TGTA 3U7YG 5F96G 5KJRG 2NY0A 3JWOA 3JWDA 3SE8G 4OLVG 4J6RG 5IGXG 4DKUA 5T33G 4R4NA 4KA2A 4OLXG 4JDTG 4I53A 2I5YG 4DVRG 4XVSG 3TIHA 2QADA 4R2GA 4XNYG 4DVXA 4DVWA 3IDYA 5F9WA 2I60G 4XVTG 2B4CG 4RWYA 4I54A 4LSSG 4H8WG 2NY6A 4LSQG 4JM2E 4K0AA 5F4UA 4JZWA 4S1RG 4S1QG 2NY1A 3IDXG 3NGBA 3TGRA 4DVTA 3FUSA 3HI1G 3RJQA 1G9NG 2NXZA 4YFLE 2NXYA 2NY4A 4DKRA 4JPVG 3TGSA 4DKPA 4DKVA 4XMPG 4DKOA 5TE6G 4LSUG 4DVSA 4YE4G 1GC1G 1RZKG 3LQAG 5F4LA 4R4FA 4XNZA 5F9OG 5FA2A 4LSPG 4DVVA 2NY3A 5FECC 4LAJA 4LSVG 5CD5A 4JKPG 5F4PA 4YDIG 4RFNA 4RX4E 4S1SG 2NY7G 4JPWG 1RZJG 4RZ8A 1G9MG
chains in the Genus database with same CATH superfamily
3SE9G 1YYLG 4DKQA 4OLUG 4YDJG 4OLWG 4OM0G 4P9HG 4RFOG 4JZZA 4LSTG 5TE7G 4YDLA 4JB9G 2NY2A 1YYMG 4OLYG 5F4RA 5CAYG 4OM1G 4OLZG 5I9QA 4LSRG 5TE4G 2NY5G 2BF1A 4YDKG 3TGQA 3TGTA 3U7YG 5F96G 5KJRG 2NY0A 3JWOA 3JWDA 3SE8G 4OLVG 4J6RG 5IGXG 4DKUA 5T33G 4R4NA 4KA2A 4OLXG 4JDTG 4I53A 2I5YG 4DVRG 4XVSG 3TIHA 2QADA 4R2GA 4XNYG 4DVXA 4DVWA 3IDYA 5F9WA 2I60G 4XVTG 2B4CG 4RWYA 4I54A 4LSSG 4H8WG 2NY6A 4LSQG 4JM2E 4K0AA 5F4UA 4JZWA 4S1RG 4S1QG 2NY1A 3IDXG 3NGBA 3TGRA 4DVTA 3FUSA 3HI1G 3RJQA 1G9NG 2NXZA 4YFLE 2NXYA 2NY4A 4DKRA 4JPVG 3TGSA 4DKPA 4DKVA 4XMPG 4DKOA 5TE6G 4LSUG 4DVSA 4YE4G 1GC1G 1RZKG 3LQAG 5F4LA 4R4FA 4XNZA 5F9OG 5FA2A 4LSPG 4DVVA 2NY3A 5FECC 4LAJA 4LSVG 5CD5A 4JKPG 5F4PA 4YDIG 4RFNA 4RX4E 4S1SG 2NY7G 4JPWG 1RZJG 4RZ8A 1G9MG
chains in the Genus database with same CATH topology
3SE9G 1YYLG 4DKQA 4OLUG 4YDJG 4OLWG 4OM0G 4P9HG 4RFOG 4JZZA 4LSTG 5TE7G 4YDLA 4JB9G 2NY2A 1YYMG 4OLYG 5F4RA 5CAYG 4OM1G 4OLZG 5I9QA 4LSRG 5TE4G 2NY5G 2BF1A 4YDKG 3TGQA 3TGTA 3U7YG 5F96G 5KJRG 2NY0A 3JWOA 3JWDA 3SE8G 4OLVG 4J6RG 5IGXG 4DKUA 5T33G 4R4NA 4KA2A 4OLXG 4JDTG 4I53A 2I5YG 4DVRG 4XVSG 3TIHA 2QADA 4R2GA 4XNYG 4DVXA 4DVWA 3IDYA 5F9WA 2I60G 4XVTG 2B4CG 4RWYA 4I54A 4LSSG 4H8WG 2NY6A 4LSQG 4JM2E 4K0AA 5F4UA 4JZWA 4S1RG 4S1QG 2NY1A 3IDXG 3NGBA 3TGRA 4DVTA 3FUSA 3HI1G 3RJQA 1G9NG 2NXZA 4YFLE 2NXYA 2NY4A 4DKRA 4JPVG 3TGSA 4DKPA 4DKVA 4XMPG 4DKOA 5TE6G 4LSUG 4DVSA 4YE4G 1GC1G 1RZKG 3LQAG 5F4LA 4R4FA 4XNZA 5F9OG 5FA2A 4LSPG 4DVVA 2NY3A 5FECC 4LAJA 4LSVG 5CD5A 4JKPG 5F4PA 4YDIG 4RFNA 4RX4E 4S1SG 2NY7G 4JPWG 1RZJG 4RZ8A 1G9MG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SE9 G;  1YYL G;  4DKQ A;  4OLU G;  4YDJ G;  4OLW G;  4OM0 G;  4P9H G;  4RFO G;  4JZZ A;  4LST G;  5TE7 G;  4YDL A;  4JB9 G;  2NY2 A;  1YYM G;  4OLY G;  5F4R A;  5CAY G;  4OM1 G;  4OLZ G;  5I9Q A;  4LSR G;  5TE4 G;  2NY5 G;  2BF1 A;  4YDK G;  3TGQ A;  3TGT A;  3U7Y G;  5F96 G;  5KJR G;  2NY0 A;  3JWO A;  3JWD A;  3SE8 G;  4OLV G;  4J6R G;  5IGX G;  4DKU A;  5T33 G;  4R4N A;  4KA2 A;  4OLX G;  4JDT G;  4I53 A;  2I5Y G;  4DVR G;  4XVS G;  3TIH A;  2QAD A;  4R2G A;  4XNY G;  4DVX A;  4DVW A;  3IDY A;  5F9W A;  2I60 G;  4XVT G;  2B4C G;  4RWY A;  4I54 A;  4LSS G;  4H8W G;  2NY6 A;  4LSQ G;  4JM2 E;  4K0A A;  5F4U A;  4JZW A;  4S1R G;  4S1Q G;  2NY1 A;  3IDX G;  3NGB A;  3TGR A;  4DVT A;  3FUS A;  3HI1 G;  3RJQ A;  1G9N G;  2NXZ A;  4YFL E;  2NXY A;  2NY4 A;  4DKR A;  4JPV G;  3TGS A;  4DKP A;  4DKV A;  4XMP G;  4DKO A;  5TE6 G;  4LSU G;  4DVS A;  4YE4 G;  1GC1 G;  1RZK G;  3LQA G;  5F4L A;  4R4F A;  4XNZ A;  5F9O G;  5FA2 A;  4LSP G;  4DVV A;  2NY3 A;  5FEC C;  4LAJ A;  4LSV G;  5CD5 A;  4JKP G;  5F4P A;  4YDI G;  4RFN A;  4RX4 E;  4S1S G;  2NY7 G;  4JPW G;  1RZJ G;  4RZ8 A;  1G9M G; 
#chains in the Genus database with same CATH topology
 3SE9 G;  1YYL G;  4DKQ A;  4OLU G;  4YDJ G;  4OLW G;  4OM0 G;  4P9H G;  4RFO G;  4JZZ A;  4LST G;  5TE7 G;  4YDL A;  4JB9 G;  2NY2 A;  1YYM G;  4OLY G;  5F4R A;  5CAY G;  4OM1 G;  4OLZ G;  5I9Q A;  4LSR G;  5TE4 G;  2NY5 G;  2BF1 A;  4YDK G;  3TGQ A;  3TGT A;  3U7Y G;  5F96 G;  5KJR G;  2NY0 A;  3JWO A;  3JWD A;  3SE8 G;  4OLV G;  4J6R G;  5IGX G;  4DKU A;  5T33 G;  4R4N A;  4KA2 A;  4OLX G;  4JDT G;  4I53 A;  2I5Y G;  4DVR G;  4XVS G;  3TIH A;  2QAD A;  4R2G A;  4XNY G;  4DVX A;  4DVW A;  3IDY A;  5F9W A;  2I60 G;  4XVT G;  2B4C G;  4RWY A;  4I54 A;  4LSS G;  4H8W G;  2NY6 A;  4LSQ G;  4JM2 E;  4K0A A;  5F4U A;  4JZW A;  4S1R G;  4S1Q G;  2NY1 A;  3IDX G;  3NGB A;  3TGR A;  4DVT A;  3FUS A;  3HI1 G;  3RJQ A;  1G9N G;  2NXZ A;  4YFL E;  2NXY A;  2NY4 A;  4DKR A;  4JPV G;  3TGS A;  4DKP A;  4DKV A;  4XMP G;  4DKO A;  5TE6 G;  4LSU G;  4DVS A;  4YE4 G;  1GC1 G;  1RZK G;  3LQA G;  5F4L A;  4R4F A;  4XNZ A;  5F9O G;  5FA2 A;  4LSP G;  4DVV A;  2NY3 A;  5FEC C;  4LAJ A;  4LSV G;  5CD5 A;  4JKP G;  5F4P A;  4YDI G;  4RFN A;  4RX4 E;  4S1S G;  2NY7 G;  4JPW G;  1RZJ G;  4RZ8 A;  1G9M G; 
#chains in the Genus database with same CATH homology
 3SE9 G;  1YYL G;  4DKQ A;  4OLU G;  4YDJ G;  4OLW G;  4OM0 G;  4P9H G;  4RFO G;  4JZZ A;  4LST G;  5TE7 G;  4YDL A;  4JB9 G;  2NY2 A;  1YYM G;  4OLY G;  5F4R A;  5CAY G;  4OM1 G;  4OLZ G;  5I9Q A;  4LSR G;  5TE4 G;  2NY5 G;  2BF1 A;  4YDK G;  3TGQ A;  3TGT A;  3U7Y G;  5F96 G;  5KJR G;  2NY0 A;  3JWO A;  3JWD A;  3SE8 G;  4OLV G;  4J6R G;  5IGX G;  4DKU A;  5T33 G;  4R4N A;  4KA2 A;  4OLX G;  4JDT G;  4I53 A;  2I5Y G;  4DVR G;  4XVS G;  3TIH A;  2QAD A;  4R2G A;  4XNY G;  4DVX A;  4DVW A;  3IDY A;  5F9W A;  2I60 G;  4XVT G;  2B4C G;  4RWY A;  4I54 A;  4LSS G;  4H8W G;  2NY6 A;  4LSQ G;  4JM2 E;  4K0A A;  5F4U A;  4JZW A;  4S1R G;  4S1Q G;  2NY1 A;  3IDX G;  3NGB A;  3TGR A;  4DVT A;  3FUS A;  3HI1 G;  3RJQ A;  1G9N G;  2NXZ A;  4YFL E;  2NXY A;  2NY4 A;  4DKR A;  4JPV G;  3TGS A;  4DKP A;  4DKV A;  4XMP G;  4DKO A;  5TE6 G;  4LSU G;  4DVS A;  4YE4 G;  1GC1 G;  1RZK G;  3LQA G;  5F4L A;  4R4F A;  4XNZ A;  5F9O G;  5FA2 A;  4LSP G;  4DVV A;  2NY3 A;  5FEC C;  4LAJ A;  4LSV G;  5CD5 A;  4JKP G;  5F4P A;  4YDI G;  4RFN A;  4RX4 E;  4S1S G;  2NY7 G;  4JPW G;  1RZJ G;  4RZ8 A;  1G9M G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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