3TQ3A

Crystal structure of m-pmv dutpase with a mixed population of substrate (dupnpp) and post-inversion product (dump) in the active sites
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
113
structure length
113
Chain Sequence
KQPISKLTRATPGSAGLDLCSTSHTVLTPEMGPQALSTGIYGPLPPNTFGLILGRSSITMKGLQVYPGVIDNDYTGEIKIMAKAVNNIVTVSQGNRIAQLILLPLIETDNKVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion
rcsb
molecule tags Hydrolase
source organism Mason-pfizer monkey virus
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDO HYDROLASE
total genus 20
structure length 113
sequence length 113
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2011-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 3tq3A01
4APZ1 1DUPA 2OKBA 4GCYA 1XS4A 5CCTA 2J4HA 3MDXA 4DHKA 2BSYA 1SJNA 3C2TA 3ZF4A 1OGHA 3TS6A 2OKEA 2D4MA 2V9XA 3SO2A 2WE0A 2XY3A 5EDDA 3EHWA 5F9KA 2XX6A 3T60A 3ZF5A 2HQUA 3HHQA 2OKDA 3LQWA 1SM8A 2YZJA 1VYQA 3ARNA 1DUNA 3T70A 1XS6A 1DUCA 1MQ7A 1XS1A 3TQ3A 1F7OA 2HXBA 3F4FA 3I93A 1SMCA 2WE2A 3C3IA 1SIXA 1EU5A 2HR6A 3TPYA 4AOZA 3ECYA 3TQ5A 2OL0A 1F7QA 2BT1A 1F7DA 3TPNA 1PKJA 3TP1A 3ZF6A 2PC5A 3TSLA 3H6DA 3ZF3A 3CA9A 3ZF1A 3LOJA 3TTAA 4WRKA 2BAZA 2QLPA 1PKHA 2WE3A 1PKKA 4OOPA 3ZF0A 3TPSA 2HXDA 1SLHA 2Y1TA 3T6YA 1Q5UX 1Q5HA 3KM3A 3GF0A 3ZF2A 2D4LA 1F7KA 2HRMA 3MBQA 1SYLA 3T64A 3P48A 4AOOA 2XCEA 1DUDA 3TRNA 2WE1A 3ZEZA 1SEHA 2OL1A 3TQZA 2QXXA 3TRLA 5ECTA 2ZDCA 4B0HA 4OOQA 3TPWA 1RN8A 2XCDA 1EUWA 4XJCA 2R9QA 3H6XA 2PY4A 2J4QA 1SNFA 1F7PA 1DUTA 4GK6A 2D4NA 4A6AA 3TQ4A 4AO5A 5CCOA 3HZAA 1F7NA 4GV8A 2Y8CA 4LHRA 1RNJA 1F7RA 3ARAA
chains in the Genus database with same CATH superfamily
4APZ1 1DUPA 2OKBA 4GCYA 1XS4A 5CCTA 2J4HA 3MDXA 4DHKA 2BSYA 1SJNA 3C2TA 3ZF4A 1OGHA 3TS6A 2OKEA 2D4MA 2V9XA 3SO2A 2WE0A 2XY3A 5EDDA 3EHWA 5F9KA 2XX6A 3T60A 3ZF5A 2HQUA 3HHQA 2OKDA 3LQWA 1SM8A 2YZJA 1VYQA 3ARNA 1DUNA 3T70A 1XS6A 1DUCA 1MQ7A 1XS1A 3TQ3A 1F7OA 2HXBA 3F4FA 3I93A 1SMCA 2WE2A 3C3IA 1SIXA 1EU5A 2HR6A 3TPYA 4AOZA 3ECYA 3TQ5A 2OL0A 1F7QA 2BT1A 1F7DA 1TULA 1PKJA 3TPNA 3TP1A 3ZF6A 2PC5A 3TSLA 3H6DA 3ZF3A 3CA9A 3ZF1A 3LOJA 3TTAA 4WRKA 2BAZA 2QLPA 1PKHA 2WE3A 1PKKA 4OOPA 3ZF0A 3TPSA 2HXDA 1SLHA 2Y1TA 3T6YA 1Q5UX 1Q5HA 3KM3A 3GF0A 3ZF2A 2D4LA 1F7KA 2HRMA 3MBQA 1SYLA 3T64A 3P48A 4AOOA 2XCEA 1DUDA 3TRNA 2WE1A 3ZEZA 1SEHA 2OL1A 3TQZA 2QXXA 3TRLA 5ECTA 2ZDCA 4B0HA 4OOQA 3TPWA 1RN8A 2XCDA 1EUWA 4XJCA 2R9QA 3H6XA 2PY4A 2J4QA 1SNFA 1F7PA 1DUTA 4GK6A 2D4NA 4A6AA 3TQ4A 4AO5A 5CCOA 3HZAA 1F7NA 4GV8A 2Y8CA 4LHRA 1RNJA 1F7RA 3ARAA
chains in the Genus database with same CATH topology
4APZ1 1DUPA 2OKBA 4GCYA 1XS4A 5CCTA 2J4HA 3MDXA 4DHKA 2BSYA 1SJNA 3C2TA 3ZF4A 1OGHA 3TS6A 2OKEA 2D4MA 2V9XA 3SO2A 2WE0A 2XY3A 5EDDA 3EHWA 5F9KA 2XX6A 3T60A 3ZF5A 2HQUA 3HHQA 2OKDA 3LQWA 1SM8A 2YZJA 1VYQA 3ARNA 1DUNA 3T70A 1XS6A 1DUCA 1MQ7A 1XS1A 3TQ3A 1F7OA 2HXBA 3F4FA 3I93A 1SMCA 2WE2A 3C3IA 1SIXA 1EU5A 2HR6A 3TPYA 4AOZA 3ECYA 3TQ5A 2OL0A 1F7QA 2BT1A 1F7DA 3TPNA 1PKJA 3TP1A 3ZF6A 2PC5A 3TSLA 3H6DA 3ZF3A 3CA9A 3ZF1A 3LOJA 3TTAA 4WRKA 2BAZA 2QLPA 1PKHA 2WE3A 1PKKA 4OOPA 3ZF0A 3TPSA 2HXDA 1SLHA 2Y1TA 3T6YA 1Q5UX 1Q5HA 3KM3A 3GF0A 3ZF2A 2D4LA 1F7KA 2HRMA 3MBQA 1SYLA 3T64A 3P48A 4AOOA 2XCEA 1DUDA 3TRNA 2WE1A 3ZEZA 1SEHA 2OL1A 3TQZA 2QXXA 3TRLA 5ECTA 2ZDCA 4B0HA 4OOQA 3TPWA 1RN8A 2XCDA 1EUWA 4XJCA 2R9QA 3H6XA 2PY4A 2J4QA 1SNFA 1F7PA 1DUTA 4GK6A 2D4NA 4A6AA 3TQ4A 4AO5A 5CCOA 3HZAA 1F7NA 4GV8A 2Y8CA 4LHRA 1RNJA 1F7RA 3ARAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4APZ 1;  1DUP A;  2OKB A;  4GCY A;  1XS4 A;  5CCT A;  2J4H A;  3MDX A;  4DHK A;  2BSY A;  1SJN A;  3C2T A;  3ZF4 A;  1OGH A;  3TS6 A;  2OKE A;  2D4M A;  2V9X A;  3SO2 A;  2WE0 A;  2XY3 A;  5EDD A;  3EHW A;  5F9K A;  2XX6 A;  3T60 A;  3ZF5 A;  2HQU A;  3HHQ A;  2OKD A;  3LQW A;  1SM8 A;  2YZJ A;  1VYQ A;  3ARN A;  1DUN A;  3T70 A;  1XS6 A;  1DUC A;  1MQ7 A;  1XS1 A;  3TQ3 A;  1F7O A;  2HXB A;  3F4F A;  3I93 A;  1SMC A;  2WE2 A;  3C3I A;  1SIX A;  1EU5 A;  2HR6 A;  3TPY A;  4AOZ A;  3ECY A;  3TQ5 A;  2OL0 A;  1F7Q A;  2BT1 A;  1F7D A;  3TPN A;  1PKJ A;  3TP1 A;  3ZF6 A;  2PC5 A;  3TSL A;  3H6D A;  3ZF3 A;  3CA9 A;  3ZF1 A;  3LOJ A;  3TTA A;  4WRK A;  2BAZ A;  2QLP A;  1PKH A;  2WE3 A;  1PKK A;  4OOP A;  3ZF0 A;  3TPS A;  2HXD A;  1SLH A;  2Y1T A;  3T6Y A;  1Q5U X;  1Q5H A;  3KM3 A;  3GF0 A;  3ZF2 A;  2D4L A;  1F7K A;  2HRM A;  3MBQ A;  1SYL A;  3T64 A;  3P48 A;  4AOO A;  2XCE A;  1DUD A;  3TRN A;  2WE1 A;  3ZEZ A;  1SEH A;  2OL1 A;  3TQZ A;  2QXX A;  3TRL A;  5ECT A;  2ZDC A;  4B0H A;  4OOQ A;  3TPW A;  1RN8 A;  2XCD A;  1EUW A;  4XJC A;  2R9Q A;  3H6X A;  2PY4 A;  2J4Q A;  1SNF A;  1F7P A;  1DUT A;  4GK6 A;  2D4N A;  4A6A A;  3TQ4 A;  4AO5 A;  5CCO A;  3HZA A;  1F7N A;  4GV8 A;  2Y8C A;  4LHR A;  1RNJ A;  1F7R A;  3ARA A; 
#chains in the Genus database with same CATH topology
 4APZ 1;  1DUP A;  2OKB A;  4GCY A;  1XS4 A;  5CCT A;  2J4H A;  3MDX A;  4DHK A;  2BSY A;  1SJN A;  3C2T A;  3ZF4 A;  1OGH A;  3TS6 A;  2OKE A;  2D4M A;  2V9X A;  3SO2 A;  2WE0 A;  2XY3 A;  5EDD A;  3EHW A;  5F9K A;  2XX6 A;  3T60 A;  3ZF5 A;  2HQU A;  3HHQ A;  2OKD A;  3LQW A;  1SM8 A;  2YZJ A;  1VYQ A;  3ARN A;  1DUN A;  3T70 A;  1XS6 A;  1DUC A;  1MQ7 A;  1XS1 A;  3TQ3 A;  1F7O A;  2HXB A;  3F4F A;  3I93 A;  1SMC A;  2WE2 A;  3C3I A;  1SIX A;  1EU5 A;  2HR6 A;  3TPY A;  4AOZ A;  3ECY A;  3TQ5 A;  2OL0 A;  1F7Q A;  2BT1 A;  1F7D A;  1TUL A;  1PKJ A;  3TPN A;  3TP1 A;  3ZF6 A;  2PC5 A;  3TSL A;  3H6D A;  3ZF3 A;  3CA9 A;  3ZF1 A;  3LOJ A;  3TTA A;  4WRK A;  2BAZ A;  2QLP A;  1PKH A;  2WE3 A;  1PKK A;  4OOP A;  3ZF0 A;  3TPS A;  2HXD A;  1SLH A;  2Y1T A;  3T6Y A;  1Q5U X;  1Q5H A;  3KM3 A;  3GF0 A;  3ZF2 A;  2D4L A;  1F7K A;  2HRM A;  3MBQ A;  1SYL A;  3T64 A;  3P48 A;  4AOO A;  2XCE A;  1DUD A;  3TRN A;  2WE1 A;  3ZEZ A;  1SEH A;  2OL1 A;  3TQZ A;  2QXX A;  3TRL A;  5ECT A;  2ZDC A;  4B0H A;  4OOQ A;  3TPW A;  1RN8 A;  2XCD A;  1EUW A;  4XJC A;  2R9Q A;  3H6X A;  2PY4 A;  2J4Q A;  1SNF A;  1F7P A;  1DUT A;  4GK6 A;  2D4N A;  4A6A A;  3TQ4 A;  4AO5 A;  5CCO A;  3HZA A;  1F7N A;  4GV8 A;  2Y8C A;  4LHR A;  1RNJ A;  1F7R A;  3ARA A; 
#chains in the Genus database with same CATH homology
 4APZ 1;  1DUP A;  2OKB A;  4GCY A;  1XS4 A;  5CCT A;  2J4H A;  3MDX A;  4DHK A;  2BSY A;  1SJN A;  3C2T A;  3ZF4 A;  1OGH A;  3TS6 A;  2OKE A;  2D4M A;  2V9X A;  3SO2 A;  2WE0 A;  2XY3 A;  5EDD A;  3EHW A;  5F9K A;  2XX6 A;  3T60 A;  3ZF5 A;  2HQU A;  3HHQ A;  2OKD A;  3LQW A;  1SM8 A;  2YZJ A;  1VYQ A;  3ARN A;  1DUN A;  3T70 A;  1XS6 A;  1DUC A;  1MQ7 A;  1XS1 A;  3TQ3 A;  1F7O A;  2HXB A;  3F4F A;  3I93 A;  1SMC A;  2WE2 A;  3C3I A;  1SIX A;  1EU5 A;  2HR6 A;  3TPY A;  4AOZ A;  3ECY A;  3TQ5 A;  2OL0 A;  1F7Q A;  2BT1 A;  1F7D A;  3TPN A;  1PKJ A;  3TP1 A;  3ZF6 A;  2PC5 A;  3TSL A;  3H6D A;  3ZF3 A;  3CA9 A;  3ZF1 A;  3LOJ A;  3TTA A;  4WRK A;  2BAZ A;  2QLP A;  1PKH A;  2WE3 A;  1PKK A;  4OOP A;  3ZF0 A;  3TPS A;  2HXD A;  1SLH A;  2Y1T A;  3T6Y A;  1Q5U X;  1Q5H A;  3KM3 A;  3GF0 A;  3ZF2 A;  2D4L A;  1F7K A;  2HRM A;  3MBQ A;  1SYL A;  3T64 A;  3P48 A;  4AOO A;  2XCE A;  1DUD A;  3TRN A;  2WE1 A;  3ZEZ A;  1SEH A;  2OL1 A;  3TQZ A;  2QXX A;  3TRL A;  5ECT A;  2ZDC A;  4B0H A;  4OOQ A;  3TPW A;  1RN8 A;  2XCD A;  1EUW A;  4XJC A;  2R9Q A;  3H6X A;  2PY4 A;  2J4Q A;  1SNF A;  1F7P A;  1DUT A;  4GK6 A;  2D4N A;  4A6A A;  3TQ4 A;  4AO5 A;  5CCO A;  3HZA A;  1F7N A;  4GV8 A;  2Y8C A;  4LHR A;  1RNJ A;  1F7R A;  3ARA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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