3TQ4A

Crystal structure of m-pmv dutpase with a mixed population of substrate (dupnpp) and post-inversion product (dump) in the active sites
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
112
structure length
112
Chain Sequence
KQPISKLTRATPGSAGLDLCSTSHTVLTPEMGPQALSTGIYGPLPPNTFGLILGRSSITMKGLQVYPGVIDNDYTGEIKIMAKAVNNIVTVSQGNRIAQLILLPLIETDNKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion
rcsb
molecule tags Hydrolase
source organism Mason-pfizer monkey virus
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDO HYDROLASE
total genus 20
structure length 112
sequence length 112
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2011-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 3tq4A01
1PKHA 4GCYA 3ZF3A 3ARNA 3TTAA 1SNFA 2HQUA 3KM3A 5EDDA 3TSLA 1SYLA 3TPYA 2WE1A 1F7KA 4WRKA 3TRNA 4GV8A 3I93A 1MQ7A 1F7QA 1EU5A 2HXBA 3ZF6A 3TPSA 1F7DA 2BAZA 2HR6A 3CA9A 3LOJA 1RN8A 4OOQA 1SMCA 3ZF1A 3T6YA 2J4HA 3H6DA 2QXXA 2XY3A 2YZJA 2HXDA 2WE0A 4AO5A 3GF0A 3ECYA 3T64A 3T70A 3MDXA 2BSYA 1SLHA 2WE3A 5ECTA 3H6XA 2OKEA 1PKJA 3TQ4A 4LHRA 3TRLA 2BT1A 3MBQA 3ARAA 2PC5A 2Y1TA 1DUNA 5CCOA 3ZF4A 3P48A 2ZDCA 4GK6A 1RNJA 1DUCA 3ZF2A 3ZEZA 3C3IA 5CCTA 2OKBA 3ZF0A 1DUPA 3TPWA 2Y8CA 2XCEA 3TQZA 3TP1A 2HRMA 2OL0A 1F7PA 2V9XA 4XJCA 3HHQA 4APZ1 1F7OA 3LQWA 2XX6A 2XCDA 3TQ3A 2PY4A 4OOPA 2QLPA 1DUDA 3EHWA 3F4FA 4AOZA 1SIXA 2OL1A 1SEHA 4B0HA 4A6AA 2R9QA 3ZF5A 2J4QA 3HZAA 1XS6A 1F7NA 1XS4A 1DUTA 3T60A 1XS1A 3SO2A 2D4MA 3TS6A 2WE2A 1SM8A 1EUWA 2D4LA 3TQ5A 4DHKA 5F9KA 2OKDA 1VYQA 3TPNA 1PKKA 1Q5HA 4AOOA 1Q5UX 1F7RA 1OGHA 3C2TA 1SJNA 2D4NA
chains in the Genus database with same CATH superfamily
1PKHA 4GCYA 3ZF3A 3ARNA 3TTAA 1SNFA 2HQUA 3KM3A 5EDDA 3TSLA 1SYLA 3TPYA 2WE1A 1F7KA 4WRKA 3TRNA 4GV8A 3I93A 1MQ7A 1F7QA 1EU5A 2HXBA 3ZF6A 3TPSA 1F7DA 2BAZA 2HR6A 3CA9A 3LOJA 1RN8A 1TULA 4OOQA 1SMCA 3ZF1A 3T6YA 2J4HA 3H6DA 2QXXA 2XY3A 2YZJA 2HXDA 2WE0A 4AO5A 3GF0A 3ECYA 3T64A 3T70A 3MDXA 2BSYA 1SLHA 2WE3A 5ECTA 3H6XA 2OKEA 1PKJA 3TQ4A 4LHRA 3TRLA 2BT1A 3MBQA 3ARAA 2PC5A 2Y1TA 1DUNA 5CCOA 3ZF4A 3P48A 2ZDCA 4GK6A 1RNJA 1DUCA 3ZF2A 3ZEZA 3C3IA 5CCTA 2OKBA 3ZF0A 1DUPA 3TPWA 2Y8CA 2XCEA 3TQZA 3TP1A 2HRMA 2OL0A 1F7PA 2V9XA 4XJCA 3HHQA 4APZ1 1F7OA 3LQWA 2XX6A 2XCDA 3TQ3A 2PY4A 4OOPA 2QLPA 1DUDA 3EHWA 3F4FA 4AOZA 1SIXA 2OL1A 1SEHA 4B0HA 4A6AA 2R9QA 3ZF5A 2J4QA 3HZAA 1XS6A 1F7NA 1XS4A 1DUTA 3T60A 1XS1A 3SO2A 2D4MA 3TS6A 2WE2A 1SM8A 1EUWA 2D4LA 3TQ5A 4DHKA 5F9KA 2OKDA 1VYQA 3TPNA 1PKKA 1Q5HA 4AOOA 1Q5UX 1F7RA 1OGHA 3C2TA 1SJNA 2D4NA
chains in the Genus database with same CATH topology
1PKHA 4GCYA 3ZF3A 3ARNA 3TTAA 1SNFA 2HQUA 3KM3A 5EDDA 3TSLA 1SYLA 3TPYA 2WE1A 1F7KA 4WRKA 3TRNA 4GV8A 3I93A 1MQ7A 1F7QA 1EU5A 2HXBA 3ZF6A 3TPSA 1F7DA 2BAZA 2HR6A 3CA9A 3LOJA 1RN8A 4OOQA 1SMCA 3ZF1A 3T6YA 2J4HA 3H6DA 2QXXA 2XY3A 2YZJA 2HXDA 2WE0A 4AO5A 3GF0A 3ECYA 3T64A 3T70A 3MDXA 2BSYA 1SLHA 2WE3A 5ECTA 3H6XA 2OKEA 1PKJA 3TQ4A 4LHRA 3TRLA 2BT1A 3MBQA 3ARAA 2PC5A 2Y1TA 1DUNA 5CCOA 3ZF4A 3P48A 2ZDCA 4GK6A 1RNJA 1DUCA 3ZF2A 3ZEZA 3C3IA 5CCTA 2OKBA 3ZF0A 1DUPA 3TPWA 2Y8CA 2XCEA 3TQZA 3TP1A 2HRMA 2OL0A 1F7PA 2V9XA 4XJCA 3HHQA 4APZ1 1F7OA 3LQWA 2XX6A 2XCDA 3TQ3A 2PY4A 4OOPA 2QLPA 1DUDA 3EHWA 3F4FA 4AOZA 1SIXA 2OL1A 1SEHA 4B0HA 4A6AA 2R9QA 3ZF5A 2J4QA 3HZAA 1XS6A 1F7NA 1XS4A 1DUTA 3T60A 1XS1A 3SO2A 2D4MA 3TS6A 2WE2A 1SM8A 1EUWA 2D4LA 3TQ5A 4DHKA 5F9KA 2OKDA 1VYQA 3TPNA 1PKKA 1Q5HA 4AOOA 1Q5UX 1F7RA 1OGHA 3C2TA 1SJNA 2D4NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PKH A;  4GCY A;  3ZF3 A;  3ARN A;  3TTA A;  1SNF A;  2HQU A;  3KM3 A;  5EDD A;  3TSL A;  1SYL A;  3TPY A;  2WE1 A;  1F7K A;  4WRK A;  3TRN A;  4GV8 A;  3I93 A;  1MQ7 A;  1F7Q A;  1EU5 A;  2HXB A;  3ZF6 A;  3TPS A;  1F7D A;  2BAZ A;  2HR6 A;  3CA9 A;  3LOJ A;  1RN8 A;  4OOQ A;  1SMC A;  3ZF1 A;  3T6Y A;  2J4H A;  3H6D A;  2QXX A;  2XY3 A;  2YZJ A;  2HXD A;  2WE0 A;  4AO5 A;  3GF0 A;  3ECY A;  3T64 A;  3T70 A;  3MDX A;  2BSY A;  1SLH A;  2WE3 A;  5ECT A;  3H6X A;  2OKE A;  1PKJ A;  3TQ4 A;  4LHR A;  3TRL A;  2BT1 A;  3MBQ A;  3ARA A;  2PC5 A;  2Y1T A;  1DUN A;  5CCO A;  3ZF4 A;  3P48 A;  2ZDC A;  4GK6 A;  1RNJ A;  1DUC A;  3ZF2 A;  3ZEZ A;  3C3I A;  5CCT A;  2OKB A;  3ZF0 A;  1DUP A;  3TPW A;  2Y8C A;  2XCE A;  3TQZ A;  3TP1 A;  2HRM A;  2OL0 A;  1F7P A;  2V9X A;  4XJC A;  3HHQ A;  4APZ 1;  1F7O A;  3LQW A;  2XX6 A;  2XCD A;  3TQ3 A;  2PY4 A;  4OOP A;  2QLP A;  1DUD A;  3EHW A;  3F4F A;  4AOZ A;  1SIX A;  2OL1 A;  1SEH A;  4B0H A;  4A6A A;  2R9Q A;  3ZF5 A;  2J4Q A;  3HZA A;  1XS6 A;  1F7N A;  1XS4 A;  1DUT A;  3T60 A;  1XS1 A;  3SO2 A;  2D4M A;  3TS6 A;  2WE2 A;  1SM8 A;  1EUW A;  2D4L A;  3TQ5 A;  4DHK A;  5F9K A;  2OKD A;  1VYQ A;  3TPN A;  1PKK A;  1Q5H A;  4AOO A;  1Q5U X;  1F7R A;  1OGH A;  3C2T A;  1SJN A;  2D4N A; 
#chains in the Genus database with same CATH topology
 1PKH A;  4GCY A;  3ZF3 A;  3ARN A;  3TTA A;  1SNF A;  2HQU A;  3KM3 A;  5EDD A;  3TSL A;  1SYL A;  3TPY A;  2WE1 A;  1F7K A;  4WRK A;  3TRN A;  4GV8 A;  3I93 A;  1MQ7 A;  1F7Q A;  1EU5 A;  2HXB A;  3ZF6 A;  3TPS A;  1F7D A;  2BAZ A;  2HR6 A;  3CA9 A;  3LOJ A;  1RN8 A;  1TUL A;  4OOQ A;  1SMC A;  3ZF1 A;  3T6Y A;  2J4H A;  3H6D A;  2QXX A;  2XY3 A;  2YZJ A;  2HXD A;  2WE0 A;  4AO5 A;  3GF0 A;  3ECY A;  3T64 A;  3T70 A;  3MDX A;  2BSY A;  1SLH A;  2WE3 A;  5ECT A;  3H6X A;  2OKE A;  1PKJ A;  3TQ4 A;  4LHR A;  3TRL A;  2BT1 A;  3MBQ A;  3ARA A;  2PC5 A;  2Y1T A;  1DUN A;  5CCO A;  3ZF4 A;  3P48 A;  2ZDC A;  4GK6 A;  1RNJ A;  1DUC A;  3ZF2 A;  3ZEZ A;  3C3I A;  5CCT A;  2OKB A;  3ZF0 A;  1DUP A;  3TPW A;  2Y8C A;  2XCE A;  3TQZ A;  3TP1 A;  2HRM A;  2OL0 A;  1F7P A;  2V9X A;  4XJC A;  3HHQ A;  4APZ 1;  1F7O A;  3LQW A;  2XX6 A;  2XCD A;  3TQ3 A;  2PY4 A;  4OOP A;  2QLP A;  1DUD A;  3EHW A;  3F4F A;  4AOZ A;  1SIX A;  2OL1 A;  1SEH A;  4B0H A;  4A6A A;  2R9Q A;  3ZF5 A;  2J4Q A;  3HZA A;  1XS6 A;  1F7N A;  1XS4 A;  1DUT A;  3T60 A;  1XS1 A;  3SO2 A;  2D4M A;  3TS6 A;  2WE2 A;  1SM8 A;  1EUW A;  2D4L A;  3TQ5 A;  4DHK A;  5F9K A;  2OKD A;  1VYQ A;  3TPN A;  1PKK A;  1Q5H A;  4AOO A;  1Q5U X;  1F7R A;  1OGH A;  3C2T A;  1SJN A;  2D4N A; 
#chains in the Genus database with same CATH homology
 1PKH A;  4GCY A;  3ZF3 A;  3ARN A;  3TTA A;  1SNF A;  2HQU A;  3KM3 A;  5EDD A;  3TSL A;  1SYL A;  3TPY A;  2WE1 A;  1F7K A;  4WRK A;  3TRN A;  4GV8 A;  3I93 A;  1MQ7 A;  1F7Q A;  1EU5 A;  2HXB A;  3ZF6 A;  3TPS A;  1F7D A;  2BAZ A;  2HR6 A;  3CA9 A;  3LOJ A;  1RN8 A;  4OOQ A;  1SMC A;  3ZF1 A;  3T6Y A;  2J4H A;  3H6D A;  2QXX A;  2XY3 A;  2YZJ A;  2HXD A;  2WE0 A;  4AO5 A;  3GF0 A;  3ECY A;  3T64 A;  3T70 A;  3MDX A;  2BSY A;  1SLH A;  2WE3 A;  5ECT A;  3H6X A;  2OKE A;  1PKJ A;  3TQ4 A;  4LHR A;  3TRL A;  2BT1 A;  3MBQ A;  3ARA A;  2PC5 A;  2Y1T A;  1DUN A;  5CCO A;  3ZF4 A;  3P48 A;  2ZDC A;  4GK6 A;  1RNJ A;  1DUC A;  3ZF2 A;  3ZEZ A;  3C3I A;  5CCT A;  2OKB A;  3ZF0 A;  1DUP A;  3TPW A;  2Y8C A;  2XCE A;  3TQZ A;  3TP1 A;  2HRM A;  2OL0 A;  1F7P A;  2V9X A;  4XJC A;  3HHQ A;  4APZ 1;  1F7O A;  3LQW A;  2XX6 A;  2XCD A;  3TQ3 A;  2PY4 A;  4OOP A;  2QLP A;  1DUD A;  3EHW A;  3F4F A;  4AOZ A;  1SIX A;  2OL1 A;  1SEH A;  4B0H A;  4A6A A;  2R9Q A;  3ZF5 A;  2J4Q A;  3HZA A;  1XS6 A;  1F7N A;  1XS4 A;  1DUT A;  3T60 A;  1XS1 A;  3SO2 A;  2D4M A;  3TS6 A;  2WE2 A;  1SM8 A;  1EUW A;  2D4L A;  3TQ5 A;  4DHK A;  5F9K A;  2OKD A;  1VYQ A;  3TPN A;  1PKK A;  1Q5H A;  4AOO A;  1Q5U X;  1F7R A;  1OGH A;  3C2T A;  1SJN A;  2D4N A; 
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similar chains in the Genus database (?% sequence similarity)
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