3U7MA

Crystal structures of the staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
185
structure length
184
Chain Sequence
MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKDHPLQPHTDAVEVLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Staphylococcus aureus
molecule keywords Peptide deformylase
total genus 51
structure length 184
sequence length 185
ec nomenclature ec 3.5.1.88: Peptide deformylase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01327 Pep_deformylase Polypeptide deformylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.45.10 Alpha Beta Alpha-Beta Complex Peptide Deformylase Peptide deformylase 3u7mA00
3G5PA 1BSJA 2KMNA 1WS0A 3PN5A 1LMHA 2OKLA 4WXLA 5CY8A 1LRUA 2EW5A 3U7MA 1LM4A 3K6LA 1VEVA 1BS6A 4JE8A 1DFFA 3G6NA 3FWXA 2W3TA 3SW8P 5JF6A 2OS1A 1S17A 1RL4A 5HGWA 5JF4A 1SV2A 3M6PA 5CPDA 1BS7A 2OS0A 5CWXA 3STRP 1ICJA 1N5NA 4WXKA 2AI7A 1ZY0A 3QU1A 5CY7A 3U7LA 3U7KA 3U7NA 4DR8A 5CXJA 1LRYA 2OS3A 2EW7A 4AL3A 5JEXA 3PN4A 4JE6A 5CVKA 5E5DA 4AL2A 3L87A 3PN6A 5JF2A 5CP0A 5JF1A 4E9AA 3UWBA 3CMDA 5JF7A 1LQWA 5JF5A 1Q1YA 4AZ4A 3M6QA 1XENA 1BS5A 3PN2A 3SVJP 1BSZA 4JE7A 4E9BA 2AIEP 5CX0A 1XEOA 1LQYA 2DEFA 1LM6A 1LMEA 1DEFA 3UWAA 3O3JA 1Y6HA 5JF0A 5JEZA 2AI9A 2AI8A 5J46A 1ZY1A 2W3UA 1BSKA 1SZZA 1WS1A 3M6OA 1RQCA 1IX1A 5KOBA 1G2AA 5CVQA 3M6RA 5I2BA 5JF8A 1VEYA 1BS8A 1ZXZA 5JF3A 1JYMA 3U04A 2EW6A 3PN3A 5JEYA 1BS4A 3G5KA 4NT8A 3OCAA 1XEMA 3E3UA 1G27A 1VEZA 2AIAA 3CPMA 5CWYA 4EOXP 5T8ZA 4DR9A 5CVPA 1V3YA
chains in the Genus database with same CATH superfamily
3G5PA 1BSJA 2KMNA 1WS0A 3PN5A 1LMHA 2OKLA 4WXLA 5CY8A 1LRUA 2EW5A 3U7MA 1LM4A 3K6LA 1VEVA 1BS6A 4JE8A 1DFFA 3G6NA 3FWXA 2W3TA 3SW8P 5JF6A 2OS1A 1S17A 1RL4A 5HGWA 5JF4A 1SV2A 3M6PA 5CPDA 1BS7A 2OS0A 5CWXA 3STRP 1ICJA 1N5NA 4WXKA 2AI7A 1ZY0A 3QU1A 5CY7A 3U7LA 3U7KA 3U7NA 4DR8A 5CXJA 1LRYA 2OS3A 2EW7A 4AL3A 5JEXA 3PN4A 4JE6A 5CVKA 5E5DA 4AL2A 3L87A 3PN6A 5JF2A 5CP0A 5JF1A 4E9AA 3UWBA 3CMDA 5JF7A 1LQWA 5JF5A 1Q1YA 4AZ4A 3M6QA 1XENA 1BS5A 3PN2A 3SVJP 1BSZA 4JE7A 4E9BA 2AIEP 5CX0A 1XEOA 1LQYA 2DEFA 1LM6A 1LMEA 1DEFA 3UWAA 3O3JA 1Y6HA 5JF0A 5JEZA 2AI9A 2AI8A 5J46A 1ZY1A 2W3UA 1BSKA 1SZZA 1WS1A 3M6OA 1RQCA 1IX1A 5KOBA 1G2AA 5CVQA 3M6RA 5I2BA 5JF8A 1VEYA 1BS8A 1ZXZA 5JF3A 1JYMA 3U04A 2EW6A 3PN3A 5JEYA 1BS4A 3G5KA 4NT8A 3OCAA 1XEMA 3E3UA 1G27A 1VEZA 2AIAA 3CPMA 5CWYA 4EOXP 5T8ZA 4DR9A 5CVPA 1V3YA
chains in the Genus database with same CATH topology
3G5PA 1BSJA 2KMNA 1WS0A 3PN5A 1LMHA 2OKLA 4WXLA 5CY8A 1LRUA 2EW5A 3U7MA 1LM4A 3K6LA 1VEVA 1BS6A 4JE8A 1DFFA 3G6NA 3FWXA 2W3TA 3SW8P 5JF6A 2OS1A 1S17A 1RL4A 5HGWA 5JF4A 1SV2A 3M6PA 5CPDA 1BS7A 2OS0A 5CWXA 3STRP 1ICJA 1N5NA 4WXKA 2AI7A 1ZY0A 3QU1A 5CY7A 3U7LA 3U7KA 3U7NA 4DR8A 5CXJA 1LRYA 2OS3A 2EW7A 4AL3A 5JEXA 3PN4A 4JE6A 5CVKA 5E5DA 4AL2A 3L87A 3PN6A 5JF2A 5CP0A 5JF1A 4E9AA 3UWBA 3CMDA 5JF7A 1LQWA 5JF5A 1Q1YA 4AZ4A 3M6QA 1XENA 1BS5A 3PN2A 3SVJP 1BSZA 4JE7A 4E9BA 2AIEP 5CX0A 1XEOA 1LQYA 2DEFA 1LM6A 1LMEA 1DEFA 3UWAA 3O3JA 1Y6HA 5JF0A 5JEZA 2AI9A 2AI8A 5J46A 1ZY1A 2W3UA 1BSKA 1SZZA 1WS1A 3M6OA 1RQCA 1IX1A 5KOBA 1G2AA 5CVQA 3M6RA 5I2BA 5JF8A 1VEYA 1BS8A 1ZXZA 5JF3A 1JYMA 3U04A 2EW6A 3PN3A 5JEYA 1BS4A 3G5KA 4NT8A 3OCAA 1XEMA 3E3UA 1G27A 1VEZA 2AIAA 3CPMA 5CWYA 4EOXP 5T8ZA 4DR9A 5CVPA 1V3YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G5P A;  1BSJ A;  2KMN A;  1WS0 A;  3PN5 A;  1LMH A;  2OKL A;  4WXL A;  5CY8 A;  1LRU A;  2EW5 A;  3U7M A;  1LM4 A;  3K6L A;  1VEV A;  1BS6 A;  4JE8 A;  1DFF A;  3G6N A;  3FWX A;  2W3T A;  3SW8 P;  5JF6 A;  2OS1 A;  1S17 A;  1RL4 A;  5HGW A;  5JF4 A;  1SV2 A;  3M6P A;  5CPD A;  1BS7 A;  2OS0 A;  5CWX A;  3STR P;  1ICJ A;  1N5N A;  4WXK A;  2AI7 A;  1ZY0 A;  3QU1 A;  5CY7 A;  3U7L A;  3U7K A;  3U7N A;  4DR8 A;  5CXJ A;  1LRY A;  2OS3 A;  2EW7 A;  4AL3 A;  5JEX A;  3PN4 A;  4JE6 A;  5CVK A;  5E5D A;  4AL2 A;  3L87 A;  3PN6 A;  5JF2 A;  5CP0 A;  5JF1 A;  4E9A A;  3UWB A;  3CMD A;  5JF7 A;  1LQW A;  5JF5 A;  1Q1Y A;  4AZ4 A;  3M6Q A;  1XEN A;  1BS5 A;  3PN2 A;  3SVJ P;  1BSZ A;  4JE7 A;  4E9B A;  2AIE P;  5CX0 A;  1XEO A;  1LQY A;  2DEF A;  1LM6 A;  1LME A;  1DEF A;  3UWA A;  3O3J A;  1Y6H A;  5JF0 A;  5JEZ A;  2AI9 A;  2AI8 A;  5J46 A;  1ZY1 A;  2W3U A;  1BSK A;  1SZZ A;  1WS1 A;  3M6O A;  1RQC A;  1IX1 A;  5KOB A;  1G2A A;  5CVQ A;  3M6R A;  5I2B A;  5JF8 A;  1VEY A;  1BS8 A;  1ZXZ A;  5JF3 A;  1JYM A;  3U04 A;  2EW6 A;  3PN3 A;  5JEY A;  1BS4 A;  3G5K A;  4NT8 A;  3OCA A;  1XEM A;  3E3U A;  1G27 A;  1VEZ A;  2AIA A;  3CPM A;  5CWY A;  4EOX P;  5T8Z A;  4DR9 A;  5CVP A;  1V3Y A; 
#chains in the Genus database with same CATH topology
 3G5P A;  1BSJ A;  2KMN A;  1WS0 A;  3PN5 A;  1LMH A;  2OKL A;  4WXL A;  5CY8 A;  1LRU A;  2EW5 A;  3U7M A;  1LM4 A;  3K6L A;  1VEV A;  1BS6 A;  4JE8 A;  1DFF A;  3G6N A;  3FWX A;  2W3T A;  3SW8 P;  5JF6 A;  2OS1 A;  1S17 A;  1RL4 A;  5HGW A;  5JF4 A;  1SV2 A;  3M6P A;  5CPD A;  1BS7 A;  2OS0 A;  5CWX A;  3STR P;  1ICJ A;  1N5N A;  4WXK A;  2AI7 A;  1ZY0 A;  3QU1 A;  5CY7 A;  3U7L A;  3U7K A;  3U7N A;  4DR8 A;  5CXJ A;  1LRY A;  2OS3 A;  2EW7 A;  4AL3 A;  5JEX A;  3PN4 A;  4JE6 A;  5CVK A;  5E5D A;  4AL2 A;  3L87 A;  3PN6 A;  5JF2 A;  5CP0 A;  5JF1 A;  4E9A A;  3UWB A;  3CMD A;  5JF7 A;  1LQW A;  5JF5 A;  1Q1Y A;  4AZ4 A;  3M6Q A;  1XEN A;  1BS5 A;  3PN2 A;  3SVJ P;  1BSZ A;  4JE7 A;  4E9B A;  2AIE P;  5CX0 A;  1XEO A;  1LQY A;  2DEF A;  1LM6 A;  1LME A;  1DEF A;  3UWA A;  3O3J A;  1Y6H A;  5JF0 A;  5JEZ A;  2AI9 A;  2AI8 A;  5J46 A;  1ZY1 A;  2W3U A;  1BSK A;  1SZZ A;  1WS1 A;  3M6O A;  1RQC A;  1IX1 A;  5KOB A;  1G2A A;  5CVQ A;  3M6R A;  5I2B A;  5JF8 A;  1VEY A;  1BS8 A;  1ZXZ A;  5JF3 A;  1JYM A;  3U04 A;  2EW6 A;  3PN3 A;  5JEY A;  1BS4 A;  3G5K A;  4NT8 A;  3OCA A;  1XEM A;  3E3U A;  1G27 A;  1VEZ A;  2AIA A;  3CPM A;  5CWY A;  4EOX P;  5T8Z A;  4DR9 A;  5CVP A;  1V3Y A; 
#chains in the Genus database with same CATH homology
 3G5P A;  1BSJ A;  2KMN A;  1WS0 A;  3PN5 A;  1LMH A;  2OKL A;  4WXL A;  5CY8 A;  1LRU A;  2EW5 A;  3U7M A;  1LM4 A;  3K6L A;  1VEV A;  1BS6 A;  4JE8 A;  1DFF A;  3G6N A;  3FWX A;  2W3T A;  3SW8 P;  5JF6 A;  2OS1 A;  1S17 A;  1RL4 A;  5HGW A;  5JF4 A;  1SV2 A;  3M6P A;  5CPD A;  1BS7 A;  2OS0 A;  5CWX A;  3STR P;  1ICJ A;  1N5N A;  4WXK A;  2AI7 A;  1ZY0 A;  3QU1 A;  5CY7 A;  3U7L A;  3U7K A;  3U7N A;  4DR8 A;  5CXJ A;  1LRY A;  2OS3 A;  2EW7 A;  4AL3 A;  5JEX A;  3PN4 A;  4JE6 A;  5CVK A;  5E5D A;  4AL2 A;  3L87 A;  3PN6 A;  5JF2 A;  5CP0 A;  5JF1 A;  4E9A A;  3UWB A;  3CMD A;  5JF7 A;  1LQW A;  5JF5 A;  1Q1Y A;  4AZ4 A;  3M6Q A;  1XEN A;  1BS5 A;  3PN2 A;  3SVJ P;  1BSZ A;  4JE7 A;  4E9B A;  2AIE P;  5CX0 A;  1XEO A;  1LQY A;  2DEF A;  1LM6 A;  1LME A;  1DEF A;  3UWA A;  3O3J A;  1Y6H A;  5JF0 A;  5JEZ A;  2AI9 A;  2AI8 A;  5J46 A;  1ZY1 A;  2W3U A;  1BSK A;  1SZZ A;  1WS1 A;  3M6O A;  1RQC A;  1IX1 A;  5KOB A;  1G2A A;  5CVQ A;  3M6R A;  5I2B A;  5JF8 A;  1VEY A;  1BS8 A;  1ZXZ A;  5JF3 A;  1JYM A;  3U04 A;  2EW6 A;  3PN3 A;  5JEY A;  1BS4 A;  3G5K A;  4NT8 A;  3OCA A;  1XEM A;  3E3U A;  1G27 A;  1VEZ A;  2AIA A;  3CPM A;  5CWY A;  4EOX P;  5T8Z A;  4DR9 A;  5CVP A;  1V3Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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