3UKRE

Crystal structure of bos taurus arp2/3 complex with bound inhibitor ck-666
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
173
structure length
173
Chain Sequence
PAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKPANKQEDEVMRAYLQQLRQETGLRLCEKVFDPQNDKPSKWWTCFVKRQFMNKSLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton.
pubmed doi rcsb
molecule tags Structural protein
molecule keywords Actin-related protein 3
total genus 55
structure length 173
sequence length 173
ec nomenclature
pdb deposition date 2011-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF04062 P21-Arc ARP2/3 complex ARPC3 (21 kDa) subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1760.10 Mainly Alpha Orthogonal Bundle Arp2/3 complex 21 kDa subunit ARPC3 Actin-related protein 2/3 complex subunit 3 3ukrE00
2P9KE 1U2VE 1TYQE 2P9PE 2P9SE 3RSEE 2P9NE 3ULEE 1K8KE 3DXKE 4JD2E 2P9IE 2P9UE 3UKUE 3DXME 3UKRE 4XEIE 2P9LE
chains in the Genus database with same CATH superfamily
2P9KE 4RFSS 3DXME 5KBWA 4MHWA 5JSZC 1U2VE 3P5NA 2P9IE 2P9UE 4M5BA 4HZUS 5KC4A 2P9PE 4M58A 4POPA 2P9NE 4N4DA 1K8KE 4DVEA 3UKUE 3UKRE 4XEIE 4MESA 4Z7FA 5KC0A 4TKRA 4HUQS 1TYQE 2P9SE 3RLBA 3RSEE 5D3MC 3ULEE 3DXKE 4JD2E 4M5CA 4MUUA 5D0YA 2P9LE 4POVA
chains in the Genus database with same CATH topology
2P9KE 1U2VE 1TYQE 2P9PE 2P9SE 3RSEE 2P9NE 3ULEE 1K8KE 3DXKE 4JD2E 2P9IE 2P9UE 3UKUE 3DXME 3UKRE 4XEIE 2P9LE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P9K E;  1U2V E;  1TYQ E;  2P9P E;  2P9S E;  3RSE E;  2P9N E;  3ULE E;  1K8K E;  3DXK E;  4JD2 E;  2P9I E;  2P9U E;  3UKU E;  3DXM E;  3UKR E;  4XEI E;  2P9L E; 
#chains in the Genus database with same CATH topology
 2P9K E;  4RFS S;  3DXM E;  5KBW A;  4MHW A;  5JSZ C;  1U2V E;  3P5N A;  2P9I E;  2P9U E;  4M5B A;  4HZU S;  5KC4 A;  2P9P E;  4M58 A;  4POP A;  2P9N E;  4N4D A;  1K8K E;  4DVE A;  3UKU E;  3UKR E;  4XEI E;  4MES A;  4Z7F A;  5KC0 A;  4TKR A;  4HUQ S;  1TYQ E;  2P9S E;  3RLB A;  3RSE E;  5D3M C;  3ULE E;  3DXK E;  4JD2 E;  4M5C A;  4MUU A;  5D0Y A;  2P9L E;  4POV A; 
#chains in the Genus database with same CATH homology
 2P9K E;  1U2V E;  1TYQ E;  2P9P E;  2P9S E;  3RSE E;  2P9N E;  3ULE E;  1K8K E;  3DXK E;  4JD2 E;  2P9I E;  2P9U E;  3UKU E;  3DXM E;  3UKR E;  4XEI E;  2P9L E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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