3UKRE

Crystal structure of bos taurus arp2/3 complex with bound inhibitor ck-666
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
173
structure length
173
Chain Sequence
PAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKPANKQEDEVMRAYLQQLRQETGLRLCEKVFDPQNDKPSKWWTCFVKRQFMNKSLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton.
pubmed doi rcsb
molecule keywords Actin-related protein 3
molecule tags Structural protein
total genus 55
structure length 173
sequence length 173
ec nomenclature
pdb deposition date 2011-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF04062 P21-Arc ARP2/3 complex ARPC3 (21 kDa) subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1760.10 Mainly Alpha Orthogonal Bundle Arp2/3 complex 21 kDa subunit ARPC3 Actin-related protein 2/3 complex subunit 3 3ukrE00
2P9PE 3DXKE 3RSEE 1K8KE 2P9UE 3DXME 4XEIE 1TYQE 2P9SE 2P9IE 3UKUE 3UKRE 2P9LE 4JD2E 2P9NE 2P9KE 3ULEE 1U2VE
chains in the Genus database with same CATH superfamily
5KBWA 4M5CA 3DXME 2P9SE 2P9IE 2P9NE 3RLBA 3P5NA 4HUQS 4HZUS 2P9PE 4POPA 3RSEE 1K8KE 2P9UE 5D3MC 4MUUA 4Z7FA 4MESA 4POVA 4MHWA 4RFSS 3ULEE 1U2VE 4XEIE 1TYQE 4M58A 4M5BA 4DVEA 5KC4A 3DXKE 4N4DA 4TKRA 5D0YA 5JSZC 5KC0A 3UKUE 3UKRE 2P9LE 4JD2E 2P9KE
chains in the Genus database with same CATH topology
2P9PE 3DXKE 3RSEE 1K8KE 2P9UE 3DXME 4XEIE 1TYQE 2P9SE 2P9IE 3UKUE 3UKRE 2P9LE 4JD2E 2P9NE 2P9KE 3ULEE 1U2VE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P9P E;  3DXK E;  3RSE E;  1K8K E;  2P9U E;  3DXM E;  4XEI E;  1TYQ E;  2P9S E;  2P9I E;  3UKU E;  3UKR E;  2P9L E;  4JD2 E;  2P9N E;  2P9K E;  3ULE E;  1U2V E; 
#chains in the Genus database with same CATH topology
 5KBW A;  4M5C A;  3DXM E;  2P9S E;  2P9I E;  2P9N E;  3RLB A;  3P5N A;  4HUQ S;  4HZU S;  2P9P E;  4POP A;  3RSE E;  1K8K E;  2P9U E;  5D3M C;  4MUU A;  4Z7F A;  4MES A;  4POV A;  4MHW A;  4RFS S;  3ULE E;  1U2V E;  4XEI E;  1TYQ E;  4M58 A;  4M5B A;  4DVE A;  5KC4 A;  3DXK E;  4N4D A;  4TKR A;  5D0Y A;  5JSZ C;  5KC0 A;  3UKU E;  3UKR E;  2P9L E;  4JD2 E;  2P9K E; 
#chains in the Genus database with same CATH homology
 2P9P E;  3DXK E;  3RSE E;  1K8K E;  2P9U E;  3DXM E;  4XEI E;  1TYQ E;  2P9S E;  2P9I E;  3UKU E;  3UKR E;  2P9L E;  4JD2 E;  2P9N E;  2P9K E;  3ULE E;  1U2V E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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