3X26 | Genus

Total Genus 59

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	59
sequence length	197
structure length	195
Chain Sequence	ENAAPAQAPVSDRAWALFRALDGKGLVPDGYVEGWKKTFEEDFSPRRGAELVARAWTDPEFRQLLLTDGTAAVAQYGYLGPQGEYIVAVEDTPTLKNVIVCSLSTAWPILGLPPTWYKSFEYRARVVREPRKVLSEMGTEIASDIEIRVYDTTAETRYMVLPQRPAGTEGWSQEQLQEIVTKDCLIGVAIPQVPT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 195 atoms

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195 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Rhodococcus erythropolis
publication title	Time-Resolved Crystallography of the Reaction Intermediate of Nitrile Hydratase: Revealing a Role for the Cysteinesulfenic Acid Ligand as a Catalytic Nucleophile. pubmed doi rcsb
molecule keywords	Nitrile hydratase subunit alpha
total genus	59
structure length	195
sequence length	197
ec nomenclature	ec 4.2.1.84: Nitrile hydratase.
pdb deposition date	2014-12-10

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02979	NHase_alpha	Nitrile hydratase, alpha chain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.330.10	Alpha Beta	Alpha-Beta Complex	Nitrile Hydratase; Chain A	Nitrile hydratase alpha /Thiocyanate hydrolase gamma	3x26A00

2ZPFA 2CZ0A 3QZ5A 2CZ1A 4FM4A 3VYHA 2DXBC 2ZZDC 3QYGA 3X24A 3A8LA 3WVEA 3X26A 1UGQA 2CYZA 2D0QA 2DPPA 1IREA 4ZGJA 2DXCC 1UGSA 2DD5C 2ZPHA 1V29A 3A8MA 3QXEA 3A8OA 3VYGC 3WVDA 1AHJA 2QDYA 4ZGEA 3X20A 4OB0A 2AHJA 4OB2A 4ZGDA 2ZPBA 3A8HA 3HHTA 2ZPGA 2ZPEA 3QYHA 2ZPIA 1UGPA 4OB3A 4OB1A 2CZ7A 2CZ6A 2ZCFA 2DD4C 1UGRA 3QZ9A 3X28A 3X25A 3A8GA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2ZPF A;  2CZ0 A;  3QZ5 A;  2CZ1 A;  4FM4 A;  3VYH A;  2DXB C;  2ZZD C;  3QYG A;  3X24 A;  3A8L A;  3WVE A;  3X26 A;  1UGQ A;  2CYZ A;  2D0Q A;  2DPP A;  1IRE A;  4ZGJ A;  2DXC C;  1UGS A;  2DD5 C;  2ZPH A;  1V29 A;  3A8M A;  3QXE A;  3A8O A;  3VYG C;  3WVD A;  1AHJ A;  2QDY A;  4ZGE A;  3X20 A;  4OB0 A;  2AHJ A;  4OB2 A;  4ZGD A;  2ZPB A;  3A8H A;  3HHT A;  2ZPG A;  2ZPE A;  3QYH A;  2ZPI A;  1UGP A;  4OB3 A;  4OB1 A;  2CZ7 A;  2CZ6 A;  2ZCF A;  2DD4 C;  1UGR A;  3QZ9 A;  3X28 A;  3X25 A;  3A8G A; 
#chains in the Genus database with same CATH topology
 2ZPF A;  2CZ0 A;  3QZ5 A;  2CZ1 A;  4FM4 A;  3VYH A;  2DXB C;  2ZZD C;  3QYG A;  3X24 A;  3A8L A;  3WVE A;  3X26 A;  1UGQ A;  2CYZ A;  2D0Q A;  2DPP A;  1IRE A;  4ZGJ A;  2DXC C;  1UGS A;  2DD5 C;  2ZPH A;  1V29 A;  3A8M A;  3QXE A;  3A8O A;  3VYG C;  3WVD A;  1AHJ A;  2QDY A;  4ZGE A;  3X20 A;  4OB0 A;  2AHJ A;  4OB2 A;  4ZGD A;  2ZPB A;  3A8H A;  3HHT A;  2ZPG A;  2ZPE A;  3QYH A;  2ZPI A;  1UGP A;  4OB3 A;  4OB1 A;  2CZ7 A;  2CZ6 A;  2ZCF A;  2DD4 C;  1UGR A;  3QZ9 A;  3X28 A;  3X25 A;  3A8G A; 
#chains in the Genus database with same CATH homology
 2ZPF A;  2CZ0 A;  3QZ5 A;  2CZ1 A;  4FM4 A;  3VYH A;  2DXB C;  2ZZD C;  3QYG A;  3X24 A;  3A8L A;  3WVE A;  3X26 A;  1UGQ A;  2CYZ A;  2D0Q A;  2DPP A;  1IRE A;  4ZGJ A;  2DXC C;  1UGS A;  2DD5 C;  2ZPH A;  1V29 A;  3A8M A;  3QXE A;  3A8O A;  3VYG C;  3WVD A;  1AHJ A;  2QDY A;  4ZGE A;  3X20 A;  4OB0 A;  2AHJ A;  4OB2 A;  4ZGD A;  2ZPB A;  3A8H A;  3HHT A;  2ZPG A;  2ZPE A;  3QYH A;  2ZPI A;  1UGP A;  4OB3 A;  4OB1 A;  2CZ7 A;  2CZ6 A;  2ZCF A;  2DD4 C;  1UGR A;  3QZ9 A;  3X28 A;  3X25 A;  3A8G A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3X26A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations