3CC42

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
49
structure length
46
Chain Sequence
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDRRNHKRRHWRRNDTDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 7
structure length 46
sequence length 49
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
2 PF00832 Ribosomal_L39 Ribosomal L39 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1620.10 Mainly Alpha Orthogonal Bundle Atp Synthase Epsilon Chain; Chain: I; Ribosomal protein L39e 3cc4200
3CMA2 1N8R3 3G712 1YJN2 3CME2 1KQS1 3CCM2 1YJ92 1K8A3 3CCJ2 3CPW1 1QVF1 3G4S2 1VQP2 1YHQ2 1VQ82 1Q863 1VQ52 1Q7Y3 3G6E2 1VQK2 2OTJ2 3I562 1VQO2 1Q813 1VQM2 3CC72 3CCQ2 3CC22 3OW21 1YI22 1K733 1JJ21 1VQN2 1M903 3CCR2 1KD13 1W2B1 1M1K3 3CCU2 1YIT2 1Q823 3CCE2 1KC83 1VQ62 3CCV2 1K9M3 1VQL2 3CXC1 3I552 1YJW2 1QVG1 3CC42 3CD62 3CCS2 1VQ92 1S722 2QA42 2QEX2 2OTL2 1YIJ2 1VQ42 1VQ72 1NJI3 3CCL2
chains in the Genus database with same CATH superfamily
2WSSI 3CMA2 1N8R3 3G712 1YJN2 3CME2 1KQS1 3CCM2 2WPDI 1YJ92 1K8A3 3CCJ2 1E79I 3ZIAI 3CPW1 1QVF1 3G4S2 1VQP2 1YHQ2 1VQ82 1Q863 1VQ52 1Q7Y3 3G6E2 1VQK2 2OTJ2 3I562 1VQO2 1Q813 3OFNI 2V7QI 1VQM2 3CC72 3CC22 3CCQ2 3OW21 1YI22 1K733 1JJ21 1VQN2 1M903 3CCR2 1KD13 1W2B1 2XOKI 3CCU2 1M1K3 1YIT2 1Q823 4YXWI 3CCE2 1KC83 1VQ62 3CCV2 1K9M3 1VQL2 3CXC1 3I552 1YJW2 2XNDI 1QVG1 3CC42 3CCS2 3CD62 1VQ92 1S722 2QA42 2QEX2 2OTL2 1YIJ2 1VQ42 1VQ72 1NJI3 3CCL2
chains in the Genus database with same CATH topology
3CMA2 1N8R3 3G712 1YJN2 3CME2 1KQS1 3CCM2 1YJ92 1K8A3 3CCJ2 3CPW1 1QVF1 3G4S2 1VQP2 1YHQ2 1VQ82 1Q863 1VQ52 1Q7Y3 3G6E2 1VQK2 2OTJ2 3I562 1VQO2 1Q813 1VQM2 3CC72 3CCQ2 3CC22 3OW21 1YI22 1K733 1JJ21 1VQN2 1M903 3CCR2 1KD13 1W2B1 1M1K3 3CCU2 1YIT2 1Q823 3CCE2 1KC83 1VQ62 3CCV2 1K9M3 1VQL2 3CXC1 3I552 1YJW2 1QVG1 3CC42 3CD62 3CCS2 1VQ92 1S722 2QA42 2QEX2 2OTL2 1YIJ2 1VQ42 1VQ72 1NJI3 3CCL2
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CMA 2;  1N8R 3;  3G71 2;  1YJN 2;  3CME 2;  1KQS 1;  3CCM 2;  1YJ9 2;  1K8A 3;  3CCJ 2;  3CPW 1;  1QVF 1;  3G4S 2;  1VQP 2;  1YHQ 2;  1VQ8 2;  1Q86 3;  1VQ5 2;  1Q7Y 3;  3G6E 2;  1VQK 2;  2OTJ 2;  3I56 2;  1VQO 2;  1Q81 3;  1VQM 2;  3CC7 2;  3CCQ 2;  3CC2 2;  3OW2 1;  1YI2 2;  1K73 3;  1JJ2 1;  1VQN 2;  1M90 3;  3CCR 2;  1KD1 3;  1W2B 1;  1M1K 3;  3CCU 2;  1YIT 2;  1Q82 3;  3CCE 2;  1KC8 3;  1VQ6 2;  3CCV 2;  1K9M 3;  1VQL 2;  3CXC 1;  3I55 2;  1YJW 2;  1QVG 1;  3CC4 2;  3CD6 2;  3CCS 2;  1VQ9 2;  1S72 2;  2QA4 2;  2QEX 2;  2OTL 2;  1YIJ 2;  1VQ4 2;  1VQ7 2;  1NJI 3;  3CCL 2; 
#chains in the Genus database with same CATH topology
 2WSS I;  3CMA 2;  1N8R 3;  3G71 2;  1YJN 2;  3CME 2;  1KQS 1;  3CCM 2;  2WPD I;  1YJ9 2;  1K8A 3;  3CCJ 2;  1E79 I;  3ZIA I;  3CPW 1;  1QVF 1;  3G4S 2;  1VQP 2;  1YHQ 2;  1VQ8 2;  1Q86 3;  1VQ5 2;  1Q7Y 3;  3G6E 2;  1VQK 2;  2OTJ 2;  3I56 2;  1VQO 2;  1Q81 3;  3OFN I;  2V7Q I;  1VQM 2;  3CC7 2;  3CC2 2;  3CCQ 2;  3OW2 1;  1YI2 2;  1K73 3;  1JJ2 1;  1VQN 2;  1M90 3;  3CCR 2;  1KD1 3;  1W2B 1;  2XOK I;  3CCU 2;  1M1K 3;  1YIT 2;  1Q82 3;  4YXW I;  3CCE 2;  1KC8 3;  1VQ6 2;  3CCV 2;  1K9M 3;  1VQL 2;  3CXC 1;  3I55 2;  1YJW 2;  2XND I;  1QVG 1;  3CC4 2;  3CCS 2;  3CD6 2;  1VQ9 2;  1S72 2;  2QA4 2;  2QEX 2;  2OTL 2;  1YIJ 2;  1VQ4 2;  1VQ7 2;  1NJI 3;  3CCL 2; 
#chains in the Genus database with same CATH homology
 3CMA 2;  1N8R 3;  3G71 2;  1YJN 2;  3CME 2;  1KQS 1;  3CCM 2;  1YJ9 2;  1K8A 3;  3CCJ 2;  3CPW 1;  1QVF 1;  3G4S 2;  1VQP 2;  1YHQ 2;  1VQ8 2;  1Q86 3;  1VQ5 2;  1Q7Y 3;  3G6E 2;  1VQK 2;  2OTJ 2;  3I56 2;  1VQO 2;  1Q81 3;  1VQM 2;  3CC7 2;  3CCQ 2;  3CC2 2;  3OW2 1;  1YI2 2;  1K73 3;  1JJ2 1;  1VQN 2;  1M90 3;  3CCR 2;  1KD1 3;  1W2B 1;  1M1K 3;  3CCU 2;  1YIT 2;  1Q82 3;  3CCE 2;  1KC8 3;  1VQ6 2;  3CCV 2;  1K9M 3;  1VQL 2;  3CXC 1;  3I55 2;  1YJW 2;  1QVG 1;  3CC4 2;  3CD6 2;  3CCS 2;  1VQ9 2;  1S72 2;  2QA4 2;  2QEX 2;  2OTL 2;  1YIJ 2;  1VQ4 2;  1VQ7 2;  1NJI 3;  3CCL 2; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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