3CC4C

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 64
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3cc4C00
1Q82E 1K9ME 1Q7YE 1YIJC 3G6EC 1S72C 1Q86E 3CMEC 1M1KE 1VQ8C 1YJNC 3CC2C 3CCSC 1YI2C 1N8RE 3CCVC 1VQ6C 1KQSC 2OTJC 1VQLC 1VQPC 3G71C 3I55C 1VQ9C 1VQ4C 1QVFC 1QVGC 3CCQC 1KC8E 2OTLC 1VQKC 5DM7C 1YJ9C 1K8AE 3CPWC 3J7YF 1VQNC 3CC4C 1K73E 3CC7C 2QA4C 1VQOC 1YJWC 1YITC 3CCEC 3CCLC 3G4SC 1KD1E 4V19F 1JJ2C 1Q81E 1YHQC 1DMGA 3CD6C 3CCRC 1VQ7C 1VQMC 1W2BC 3OW2C 1VQ5C 3CXCC 3CCMC 1NJIE 3I56C 3CCJC 2QEXC 3CMAC 1M90E 3CCUC
chains in the Genus database with same CATH superfamily
1Q82E 1K9ME 1Q7YE 1YIJC 3G6EC 1S72C 1Q86E 3CMEC 1M1KE 1VQ8C 1YJNC 3CC2C 3CCSC 1YI2C 1N8RE 3CCVC 1VQ6C 1KQSC 2OTJC 1VQLC 1VQPC 3G71C 3I55C 1VQ9C 1VQ4C 1QVFC 1QVGC 3CCQC 1KC8E 2OTLC 1VQKC 5DM7C 1YJ9C 1K8AE 3CPWC 3J7YF 1VQNC 3CC4C 1K73E 3CC7C 2QA4C 1VQOC 1YJWC 1YITC 3CCEC 3CCLC 3G4SC 1KD1E 4V19F 1JJ2C 1Q81E 1YHQC 1DMGA 3CD6C 3CCRC 1VQ7C 1VQMC 1W2BC 3OW2C 1VQ5C 3CXCC 3CCMC 1NJIE 3I56C 3CCJC 2QEXC 3CMAC 1M90E 3CCUC
chains in the Genus database with same CATH topology
1Q82E 1K9ME 1Q7YE 1YIJC 3G6EC 1S72C 1Q86E 3CMEC 1M1KE 1VQ8C 1YJNC 3CC2C 3CCSC 1YI2C 1N8RE 3CCVC 1VQ6C 1KQSC 2OTJC 1VQLC 1VQPC 3G71C 3I55C 1VQ9C 1VQ4C 1QVFC 1QVGC 3CCQC 1KC8E 2OTLC 1VQKC 5DM7C 1YJ9C 1K8AE 3CPWC 3J7YF 1VQNC 3CC4C 1K73E 3CC7C 2QA4C 1VQOC 1YJWC 1YITC 3CCEC 3CCLC 3G4SC 1KD1E 4V19F 1JJ2C 1Q81E 1YHQC 1DMGA 3CD6C 3CCRC 1VQ7C 1VQMC 1W2BC 3OW2C 1VQ5C 3CXCC 3CCMC 1NJIE 3I56C 3CCJC 2QEXC 3CMAC 1M90E 3CCUC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q82 E;  1K9M E;  1Q7Y E;  1YIJ C;  3G6E C;  1S72 C;  1Q86 E;  3CME C;  1M1K E;  1VQ8 C;  1YJN C;  3CC2 C;  3CCS C;  1YI2 C;  1N8R E;  3CCV C;  1VQ6 C;  1KQS C;  2OTJ C;  1VQL C;  1VQP C;  3G71 C;  3I55 C;  1VQ9 C;  1VQ4 C;  1QVF C;  1QVG C;  3CCQ C;  1KC8 E;  2OTL C;  1VQK C;  5DM7 C;  1YJ9 C;  1K8A E;  3CPW C;  3J7Y F;  1VQN C;  3CC4 C;  1K73 E;  3CC7 C;  2QA4 C;  1VQO C;  1YJW C;  1YIT C;  3CCE C;  3CCL C;  3G4S C;  1KD1 E;  4V19 F;  1JJ2 C;  1Q81 E;  1YHQ C;  1DMG A;  3CD6 C;  3CCR C;  1VQ7 C;  1VQM C;  1W2B C;  3OW2 C;  1VQ5 C;  3CXC C;  3CCM C;  1NJI E;  3I56 C;  3CCJ C;  2QEX C;  3CMA C;  1M90 E;  3CCU C; 
#chains in the Genus database with same CATH topology
 1Q82 E;  1K9M E;  1Q7Y E;  1YIJ C;  3G6E C;  1S72 C;  1Q86 E;  3CME C;  1M1K E;  1VQ8 C;  1YJN C;  3CC2 C;  3CCS C;  1YI2 C;  1N8R E;  3CCV C;  1VQ6 C;  1KQS C;  2OTJ C;  1VQL C;  1VQP C;  3G71 C;  3I55 C;  1VQ9 C;  1VQ4 C;  1QVF C;  1QVG C;  3CCQ C;  1KC8 E;  2OTL C;  1VQK C;  5DM7 C;  1YJ9 C;  1K8A E;  3CPW C;  3J7Y F;  1VQN C;  3CC4 C;  1K73 E;  3CC7 C;  2QA4 C;  1VQO C;  1YJW C;  1YIT C;  3CCE C;  3CCL C;  3G4S C;  1KD1 E;  4V19 F;  1JJ2 C;  1Q81 E;  1YHQ C;  1DMG A;  3CD6 C;  3CCR C;  1VQ7 C;  1VQM C;  1W2B C;  3OW2 C;  1VQ5 C;  3CXC C;  3CCM C;  1NJI E;  3I56 C;  3CCJ C;  2QEX C;  3CMA C;  1M90 E;  3CCU C; 
#chains in the Genus database with same CATH homology
 1Q82 E;  1K9M E;  1Q7Y E;  1YIJ C;  3G6E C;  1S72 C;  1Q86 E;  3CME C;  1M1K E;  1VQ8 C;  1YJN C;  3CC2 C;  3CCS C;  1YI2 C;  1N8R E;  3CCV C;  1VQ6 C;  1KQS C;  2OTJ C;  1VQL C;  1VQP C;  3G71 C;  3I55 C;  1VQ9 C;  1VQ4 C;  1QVF C;  1QVG C;  3CCQ C;  1KC8 E;  2OTL C;  1VQK C;  5DM7 C;  1YJ9 C;  1K8A E;  3CPW C;  3J7Y F;  1VQN C;  3CC4 C;  1K73 E;  3CC7 C;  2QA4 C;  1VQO C;  1YJW C;  1YIT C;  3CCE C;  3CCL C;  3G4S C;  1KD1 E;  4V19 F;  1JJ2 C;  1Q81 E;  1YHQ C;  1DMG A;  3CD6 C;  3CCR C;  1VQ7 C;  1VQM C;  1W2B C;  3OW2 C;  1VQ5 C;  3CXC C;  3CCM C;  1NJI E;  3I56 C;  3CCJ C;  2QEX C;  3CMA C;  1M90 E;  3CCU C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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