3CC4M

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
194
structure length
194
Chain Sequence
ARSAYSYIRDAWKNPGDGQLAELQWQRQQEWRNEGAVERIERPTRLDKARSQGYKAKQGVIVARVSVRKGSARKRRHKAGRRSKRQGVTRITRRKDIQRVAEERASRTFPNLRVLNSYSVGQDGRQKWHEVILIDPNHPAIQNDDDLSWICADDQADRVFRGLTGAGRRNRGLSGKGKGSEKTRPSLRSNGGKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 57
structure length 194
sequence length 194
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00827 Ribosomal_L15e Ribosomal L15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1120.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal protein L15e Ribosomal protein l15e 3cc4M00
2QA4M 1JJ2L 1M1KN 1KD1N 3CD6M 1VQ9M 3CC7M 1YIJM 1VQ7M 3G71M 3CXCL 3CCRM 1VQKM 3CCQM 1N8RN 1QVFL 1YJ9M 3CMAM 1S72M 2OTLM 1KQSL 1YJNM 3CCMM 1VQPM 3CCEM 1VQ5M 3CCSM 3CC4M 3CCJM 1YITM 1YJWM 1Q81N 2QEXM 1VQMM 1QVGL 1M90N 3CPWL 1VQLM 1KC8N 1K8AN 1VQ8M 3CCLM 1K9MN 1VQNM 3G6EM 1YHQM 1VQ6M 1Q86N 3CMEM 3I56M 1VQ4M 3CCVM 2OTJM 3OW2L 1YI2M 1Q7YN 3I55M 1NJIN 1W2BL 3CCUM 1VQOM 1Q82N 3G4SM 1K73N 3CC2M
chains in the Genus database with same CATH superfamily
2QA4M 1JJ2L 1M1KN 1KD1N 3CD6M 1VQ9M 3CC7M 1YIJM 1VQ7M 3G71M 3CXCL 3CCRM 1VQKM 3CCQM 1N8RN 1QVFL 1YJ9M 3CMAM 1S72M 2OTLM 1KQSL 1YJNM 3CCMM 1VQPM 3CCEM 1VQ5M 3CCSM 3CC4M 3CCJM 1YITM 1YJWM 1Q81N 2QEXM 1VQMM 1QVGL 1M90N 3CPWL 1VQLM 1KC8N 1K8AN 1VQ8M 3CCLM 1K9MN 1VQNM 3G6EM 1YHQM 1VQ6M 1Q86N 3CMEM 3I56M 1VQ4M 3CCVM 2OTJM 3OW2L 1YI2M 1Q7YN 3I55M 1NJIN 1W2BL 3CCUM 1VQOM 1Q82N 3G4SM 1K73N 3CC2M
chains in the Genus database with same CATH topology
2QA4M 1JJ2L 1M1KN 1KD1N 3CD6M 1VQ9M 3CC7M 1YIJM 1VQ7M 3G71M 3CXCL 3CCRM 1VQKM 3CCQM 1N8RN 1QVFL 1YJ9M 3CMAM 1S72M 2OTLM 1KQSL 1YJNM 3CCMM 1VQPM 3CCEM 1VQ5M 3CCSM 3CC4M 3CCJM 1YITM 1YJWM 1Q81N 2QEXM 1VQMM 1QVGL 1M90N 3CPWL 1VQLM 1KC8N 1K8AN 1VQ8M 3CCLM 1K9MN 1VQNM 3G6EM 1YHQM 1VQ6M 1Q86N 3CMEM 3I56M 1VQ4M 3CCVM 2OTJM 3OW2L 1YI2M 1Q7YN 3I55M 1NJIN 1W2BL 3CCUM 1VQOM 1Q82N 3G4SM 1K73N 3CC2M
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QA4 M;  1JJ2 L;  1M1K N;  1KD1 N;  3CD6 M;  1VQ9 M;  3CC7 M;  1YIJ M;  1VQ7 M;  3G71 M;  3CXC L;  3CCR M;  1VQK M;  3CCQ M;  1N8R N;  1QVF L;  1YJ9 M;  3CMA M;  1S72 M;  2OTL M;  1KQS L;  1YJN M;  3CCM M;  1VQP M;  3CCE M;  1VQ5 M;  3CCS M;  3CC4 M;  3CCJ M;  1YIT M;  1YJW M;  1Q81 N;  2QEX M;  1VQM M;  1QVG L;  1M90 N;  3CPW L;  1VQL M;  1KC8 N;  1K8A N;  1VQ8 M;  3CCL M;  1K9M N;  1VQN M;  3G6E M;  1YHQ M;  1VQ6 M;  1Q86 N;  3CME M;  3I56 M;  1VQ4 M;  3CCV M;  2OTJ M;  3OW2 L;  1YI2 M;  1Q7Y N;  3I55 M;  1NJI N;  1W2B L;  3CCU M;  1VQO M;  1Q82 N;  3G4S M;  1K73 N;  3CC2 M; 
#chains in the Genus database with same CATH topology
 2QA4 M;  1JJ2 L;  1M1K N;  1KD1 N;  3CD6 M;  1VQ9 M;  3CC7 M;  1YIJ M;  1VQ7 M;  3G71 M;  3CXC L;  3CCR M;  1VQK M;  3CCQ M;  1N8R N;  1QVF L;  1YJ9 M;  3CMA M;  1S72 M;  2OTL M;  1KQS L;  1YJN M;  3CCM M;  1VQP M;  3CCE M;  1VQ5 M;  3CCS M;  3CC4 M;  3CCJ M;  1YIT M;  1YJW M;  1Q81 N;  2QEX M;  1VQM M;  1QVG L;  1M90 N;  3CPW L;  1VQL M;  1KC8 N;  1K8A N;  1VQ8 M;  3CCL M;  1K9M N;  1VQN M;  3G6E M;  1YHQ M;  1VQ6 M;  1Q86 N;  3CME M;  3I56 M;  1VQ4 M;  3CCV M;  2OTJ M;  3OW2 L;  1YI2 M;  1Q7Y N;  3I55 M;  1NJI N;  1W2B L;  3CCU M;  1VQO M;  1Q82 N;  3G4S M;  1K73 N;  3CC2 M; 
#chains in the Genus database with same CATH homology
 2QA4 M;  1JJ2 L;  1M1K N;  1KD1 N;  3CD6 M;  1VQ9 M;  3CC7 M;  1YIJ M;  1VQ7 M;  3G71 M;  3CXC L;  3CCR M;  1VQK M;  3CCQ M;  1N8R N;  1QVF L;  1YJ9 M;  3CMA M;  1S72 M;  2OTL M;  1KQS L;  1YJN M;  3CCM M;  1VQP M;  3CCE M;  1VQ5 M;  3CCS M;  3CC4 M;  3CCJ M;  1YIT M;  1YJW M;  1Q81 N;  2QEX M;  1VQM M;  1QVG L;  1M90 N;  3CPW L;  1VQL M;  1KC8 N;  1K8A N;  1VQ8 M;  3CCL M;  1K9M N;  1VQN M;  3G6E M;  1YHQ M;  1VQ6 M;  1Q86 N;  3CME M;  3I56 M;  1VQ4 M;  3CCV M;  2OTJ M;  3OW2 L;  1YI2 M;  1Q7Y N;  3I55 M;  1NJI N;  1W2B L;  3CCU M;  1VQO M;  1Q82 N;  3G4S M;  1K73 N;  3CC2 M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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