3CC72

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2487u
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
49
structure length
46
Chain Sequence
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDRRNHKRRHWRRNDTDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 10
structure length 46
sequence length 49
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
2 PF00832 Ribosomal_L39 Ribosomal L39 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1620.10 Mainly Alpha Orthogonal Bundle Atp Synthase Epsilon Chain; Chain: I; Ribosomal protein L39e 3cc7200
1VQP2 2OTL2 1N8R3 1VQ72 2OTJ2 3CCS2 1QVF1 3CD62 1QVG1 1Q7Y3 3G6E2 3CPW1 1YJ92 3CCR2 3CME2 3CCM2 3CC42 1VQO2 2QA42 1YHQ2 3CC72 3CCE2 3CXC1 1Q823 1K9M3 3G712 1M1K3 1VQL2 1M903 1K733 3G4S2 3I552 1Q863 3CCL2 3CMA2 3OW21 1KD13 2QEX2 3I562 1VQ52 1VQN2 1YIT2 1K8A3 1NJI3 1KQS1 1VQ42 1YJN2 1YIJ2 3CCV2 3CCQ2 1VQ92 1VQ62 1VQ82 1Q813 3CCU2 1YI22 1VQK2 3CC22 1VQM2 1KC83 1S722 1W2B1 1JJ21 3CCJ2 1YJW2
chains in the Genus database with same CATH superfamily
1VQP2 2OTL2 4YXWI 1N8R3 1VQ72 2OTJ2 3CCS2 1QVF1 1E79I 3CD62 1QVG1 1Q7Y3 3G6E2 3OFNI 2V7QI 3CPW1 2XNDI 3CCR2 2WPDI 1YJ92 3CME2 3CCM2 3CC42 1VQO2 2QA42 1YHQ2 3CC72 3CCE2 3CXC1 2WSSI 1Q823 1K9M3 3G712 1M1K3 1VQL2 1M903 1K733 2XOKI 3G4S2 3I552 1Q863 3CCL2 3CMA2 3OW21 1KD13 2QEX2 3I562 1VQ52 1VQN2 1YIT2 1K8A3 1NJI3 1KQS1 1VQ42 1YJN2 1YIJ2 3CCV2 3CCQ2 1VQ92 1VQ62 1VQ82 1Q813 3CCU2 1YI22 1VQK2 3CC22 3ZIAI 1VQM2 1KC83 1S722 1W2B1 1JJ21 3CCJ2 1YJW2
chains in the Genus database with same CATH topology
1VQP2 2OTL2 1N8R3 1VQ72 2OTJ2 3CCS2 1QVF1 3CD62 1QVG1 1Q7Y3 3G6E2 3CPW1 1YJ92 3CCR2 3CME2 3CCM2 3CC42 1VQO2 2QA42 1YHQ2 3CC72 3CCE2 3CXC1 1Q823 1K9M3 3G712 1M1K3 1VQL2 1M903 1K733 3G4S2 3I552 1Q863 3CCL2 3CMA2 3OW21 1KD13 2QEX2 3I562 1VQ52 1VQN2 1YIT2 1K8A3 1NJI3 1KQS1 1VQ42 1YJN2 1YIJ2 3CCV2 3CCQ2 1VQ92 1VQ62 1VQ82 1Q813 3CCU2 1YI22 1VQK2 3CC22 1VQM2 1KC83 1S722 1W2B1 1JJ21 3CCJ2 1YJW2
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQP 2;  2OTL 2;  1N8R 3;  1VQ7 2;  2OTJ 2;  3CCS 2;  1QVF 1;  3CD6 2;  1QVG 1;  1Q7Y 3;  3G6E 2;  3CPW 1;  1YJ9 2;  3CCR 2;  3CME 2;  3CCM 2;  3CC4 2;  1VQO 2;  2QA4 2;  1YHQ 2;  3CC7 2;  3CCE 2;  3CXC 1;  1Q82 3;  1K9M 3;  3G71 2;  1M1K 3;  1VQL 2;  1M90 3;  1K73 3;  3G4S 2;  3I55 2;  1Q86 3;  3CCL 2;  3CMA 2;  3OW2 1;  1KD1 3;  2QEX 2;  3I56 2;  1VQ5 2;  1VQN 2;  1YIT 2;  1K8A 3;  1NJI 3;  1KQS 1;  1VQ4 2;  1YJN 2;  1YIJ 2;  3CCV 2;  3CCQ 2;  1VQ9 2;  1VQ6 2;  1VQ8 2;  1Q81 3;  3CCU 2;  1YI2 2;  1VQK 2;  3CC2 2;  1VQM 2;  1KC8 3;  1S72 2;  1W2B 1;  1JJ2 1;  3CCJ 2;  1YJW 2; 
#chains in the Genus database with same CATH topology
 1VQP 2;  2OTL 2;  4YXW I;  1N8R 3;  1VQ7 2;  2OTJ 2;  3CCS 2;  1QVF 1;  1E79 I;  3CD6 2;  1QVG 1;  1Q7Y 3;  3G6E 2;  3OFN I;  2V7Q I;  3CPW 1;  2XND I;  3CCR 2;  2WPD I;  1YJ9 2;  3CME 2;  3CCM 2;  3CC4 2;  1VQO 2;  2QA4 2;  1YHQ 2;  3CC7 2;  3CCE 2;  3CXC 1;  2WSS I;  1Q82 3;  1K9M 3;  3G71 2;  1M1K 3;  1VQL 2;  1M90 3;  1K73 3;  2XOK I;  3G4S 2;  3I55 2;  1Q86 3;  3CCL 2;  3CMA 2;  3OW2 1;  1KD1 3;  2QEX 2;  3I56 2;  1VQ5 2;  1VQN 2;  1YIT 2;  1K8A 3;  1NJI 3;  1KQS 1;  1VQ4 2;  1YJN 2;  1YIJ 2;  3CCV 2;  3CCQ 2;  1VQ9 2;  1VQ6 2;  1VQ8 2;  1Q81 3;  3CCU 2;  1YI2 2;  1VQK 2;  3CC2 2;  3ZIA I;  1VQM 2;  1KC8 3;  1S72 2;  1W2B 1;  1JJ2 1;  3CCJ 2;  1YJW 2; 
#chains in the Genus database with same CATH homology
 1VQP 2;  2OTL 2;  1N8R 3;  1VQ7 2;  2OTJ 2;  3CCS 2;  1QVF 1;  3CD6 2;  1QVG 1;  1Q7Y 3;  3G6E 2;  3CPW 1;  1YJ9 2;  3CCR 2;  3CME 2;  3CCM 2;  3CC4 2;  1VQO 2;  2QA4 2;  1YHQ 2;  3CC7 2;  3CCE 2;  3CXC 1;  1Q82 3;  1K9M 3;  3G71 2;  1M1K 3;  1VQL 2;  1M90 3;  1K73 3;  3G4S 2;  3I55 2;  1Q86 3;  3CCL 2;  3CMA 2;  3OW2 1;  1KD1 3;  2QEX 2;  3I56 2;  1VQ5 2;  1VQN 2;  1YIT 2;  1K8A 3;  1NJI 3;  1KQS 1;  1VQ4 2;  1YJN 2;  1YIJ 2;  3CCV 2;  3CCQ 2;  1VQ9 2;  1VQ6 2;  1VQ8 2;  1Q81 3;  3CCU 2;  1YI2 2;  1VQK 2;  3CC2 2;  1VQM 2;  1KC8 3;  1S72 2;  1W2B 1;  1JJ2 1;  3CCJ 2;  1YJW 2; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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