3CC7C

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2487u
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 59
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3cc7C00
3CCQC 1YJ9C 1M1KE 3OW2C 1KQSC 1VQ4C 1W2BC 2QA4C 3I55C 1VQ7C 1YIJC 3CD6C 1VQ6C 1Q81E 1VQNC 3G4SC 3CC7C 1VQLC 3CCEC 1YJWC 1KD1E 1K9ME 3CCVC 3CXCC 3CCMC 1JJ2C 3G71C 2OTLC 1QVFC 1KC8E 3CCRC 1K73E 1NJIE 3CMEC 3CC2C 3CCSC 1YHQC 3CPWC 3CMAC 3CCJC 1S72C 1VQ9C 1VQKC 1VQPC 3CCLC 5DM7C 3CCUC 3G6EC 1M90E 3J7YF 2QEXC 3CC4C 1VQMC 1QVGC 1K8AE 1YITC 1VQ5C 4V19F 1Q82E 1Q86E 1YI2C 1VQ8C 1N8RE 3I56C 1VQOC 2OTJC 1Q7YE 1YJNC 1DMGA
chains in the Genus database with same CATH superfamily
3CCQC 1YJ9C 1M1KE 3OW2C 1KQSC 1VQ4C 1W2BC 2QA4C 3I55C 1VQ7C 1YIJC 3CD6C 1VQ6C 1Q81E 1VQNC 3G4SC 3CC7C 1VQLC 3CCEC 1YJWC 1KD1E 1K9ME 3CCVC 3CXCC 3CCMC 1JJ2C 3G71C 2OTLC 1QVFC 1KC8E 3CCRC 1K73E 1NJIE 3CMEC 3CC2C 3CCSC 1YHQC 3CPWC 3CMAC 3CCJC 1S72C 1VQ9C 1VQKC 1VQPC 3CCLC 5DM7C 3CCUC 3G6EC 1M90E 3J7YF 2QEXC 3CC4C 1VQMC 1QVGC 1K8AE 1YITC 1VQ5C 4V19F 1Q82E 1Q86E 1YI2C 1VQ8C 1N8RE 3I56C 1VQOC 2OTJC 1Q7YE 1YJNC 1DMGA
chains in the Genus database with same CATH topology
3CCQC 1YJ9C 1M1KE 3OW2C 1KQSC 1VQ4C 1W2BC 2QA4C 3I55C 1VQ7C 1YIJC 3CD6C 1VQ6C 1Q81E 1VQNC 3G4SC 3CC7C 1VQLC 3CCEC 1YJWC 1KD1E 1K9ME 3CCVC 3CXCC 3CCMC 1JJ2C 3G71C 2OTLC 1QVFC 1KC8E 3CCRC 1K73E 1NJIE 3CMEC 3CC2C 3CCSC 1YHQC 3CPWC 3CMAC 3CCJC 1S72C 1VQ9C 1VQKC 1VQPC 3CCLC 5DM7C 3CCUC 3G6EC 1M90E 3J7YF 2QEXC 3CC4C 1VQMC 1QVGC 1K8AE 1YITC 1VQ5C 4V19F 1Q82E 1Q86E 1YI2C 1VQ8C 1N8RE 3I56C 1VQOC 2OTJC 1Q7YE 1YJNC 1DMGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCQ C;  1YJ9 C;  1M1K E;  3OW2 C;  1KQS C;  1VQ4 C;  1W2B C;  2QA4 C;  3I55 C;  1VQ7 C;  1YIJ C;  3CD6 C;  1VQ6 C;  1Q81 E;  1VQN C;  3G4S C;  3CC7 C;  1VQL C;  3CCE C;  1YJW C;  1KD1 E;  1K9M E;  3CCV C;  3CXC C;  3CCM C;  1JJ2 C;  3G71 C;  2OTL C;  1QVF C;  1KC8 E;  3CCR C;  1K73 E;  1NJI E;  3CME C;  3CC2 C;  3CCS C;  1YHQ C;  3CPW C;  3CMA C;  3CCJ C;  1S72 C;  1VQ9 C;  1VQK C;  1VQP C;  3CCL C;  5DM7 C;  3CCU C;  3G6E C;  1M90 E;  3J7Y F;  2QEX C;  3CC4 C;  1VQM C;  1QVG C;  1K8A E;  1YIT C;  1VQ5 C;  4V19 F;  1Q82 E;  1Q86 E;  1YI2 C;  1VQ8 C;  1N8R E;  3I56 C;  1VQO C;  2OTJ C;  1Q7Y E;  1YJN C;  1DMG A; 
#chains in the Genus database with same CATH topology
 3CCQ C;  1YJ9 C;  1M1K E;  3OW2 C;  1KQS C;  1VQ4 C;  1W2B C;  2QA4 C;  3I55 C;  1VQ7 C;  1YIJ C;  3CD6 C;  1VQ6 C;  1Q81 E;  1VQN C;  3G4S C;  3CC7 C;  1VQL C;  3CCE C;  1YJW C;  1KD1 E;  1K9M E;  3CCV C;  3CXC C;  3CCM C;  1JJ2 C;  3G71 C;  2OTL C;  1QVF C;  1KC8 E;  3CCR C;  1K73 E;  1NJI E;  3CME C;  3CC2 C;  3CCS C;  1YHQ C;  3CPW C;  3CMA C;  3CCJ C;  1S72 C;  1VQ9 C;  1VQK C;  1VQP C;  3CCL C;  5DM7 C;  3CCU C;  3G6E C;  1M90 E;  3J7Y F;  2QEX C;  3CC4 C;  1VQM C;  1QVG C;  1K8A E;  1YIT C;  1VQ5 C;  4V19 F;  1Q82 E;  1Q86 E;  1YI2 C;  1VQ8 C;  1N8R E;  3I56 C;  1VQO C;  2OTJ C;  1Q7Y E;  1YJN C;  1DMG A; 
#chains in the Genus database with same CATH homology
 3CCQ C;  1YJ9 C;  1M1K E;  3OW2 C;  1KQS C;  1VQ4 C;  1W2B C;  2QA4 C;  3I55 C;  1VQ7 C;  1YIJ C;  3CD6 C;  1VQ6 C;  1Q81 E;  1VQN C;  3G4S C;  3CC7 C;  1VQL C;  3CCE C;  1YJW C;  1KD1 E;  1K9M E;  3CCV C;  3CXC C;  3CCM C;  1JJ2 C;  3G71 C;  2OTL C;  1QVF C;  1KC8 E;  3CCR C;  1K73 E;  1NJI E;  3CME C;  3CC2 C;  3CCS C;  1YHQ C;  3CPW C;  3CMA C;  3CCJ C;  1S72 C;  1VQ9 C;  1VQK C;  1VQP C;  3CCL C;  5DM7 C;  3CCU C;  3G6E C;  1M90 E;  3J7Y F;  2QEX C;  3CC4 C;  1VQM C;  1QVG C;  1K8A E;  1YIT C;  1VQ5 C;  4V19 F;  1Q82 E;  1Q86 E;  1YI2 C;  1VQ8 C;  1N8R E;  3I56 C;  1VQO C;  2OTJ C;  1Q7Y E;  1YJN C;  1DMG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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