3CCEM

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
194
structure length
194
Chain Sequence
ARSAYSYIRDAWKNPGDGQLAELQWQRQQEWRNEGAVERIERPTRLDKARSQGYKAKQGVIVARVSVRKGSARKRRHKAGRRSKRQGVTRITRRKDIQRVAEERASRTFPNLRVLNSYSVGQDGRQKWHEVILIDPNHPAIQNDDDLSWICADDQADRVFRGLTGAGRRNRGLSGKGKGSEKTRPSLRSNGGKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 56
structure length 194
sequence length 194
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00827 Ribosomal_L15e Ribosomal L15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1120.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal protein L15e Ribosomal protein l15e 3cceM00
1M1KN 1K8AN 2QA4M 3CPWL 1Q82N 3CCUM 1QVGL 1K9MN 1M90N 3G6EM 1YITM 3CCSM 1VQ4M 2QEXM 3CCJM 1YJWM 3G4SM 1KC8N 1VQ9M 3CC4M 3CCQM 1VQMM 1VQ6M 3CC2M 3CCEM 2OTJM 2OTLM 1Q7YN 1VQ8M 1Q86N 3CMEM 3CCLM 1VQ7M 1VQNM 1VQOM 1YJ9M 3CD6M 3I55M 1W2BL 1Q81N 1JJ2L 1VQ5M 1S72M 3CXCL 3I56M 3CCMM 3CMAM 1YI2M 1N8RN 3CCRM 1YJNM 1YIJM 1YHQM 3OW2L 1VQLM 1NJIN 1VQKM 3G71M 1VQPM 3CCVM 1KD1N 1KQSL 3CC7M 1QVFL 1K73N
chains in the Genus database with same CATH superfamily
1M1KN 1K8AN 2QA4M 3CPWL 1Q82N 3CCUM 1QVGL 1K9MN 1M90N 3G6EM 1YITM 3CCSM 1VQ4M 2QEXM 3CCJM 1YJWM 3G4SM 1KC8N 1VQ9M 3CC4M 3CCQM 1VQMM 1VQ6M 3CC2M 3CCEM 2OTJM 2OTLM 1Q7YN 1VQ8M 1Q86N 3CMEM 3CCLM 1VQ7M 1VQNM 1VQOM 1YJ9M 3CD6M 3I55M 1W2BL 1Q81N 1JJ2L 1VQ5M 1S72M 3CXCL 3I56M 3CCMM 3CMAM 1YI2M 1N8RN 3CCRM 1YJNM 1YIJM 1YHQM 3OW2L 1VQLM 1NJIN 1VQKM 3G71M 1VQPM 3CCVM 1KD1N 1KQSL 3CC7M 1QVFL 1K73N
chains in the Genus database with same CATH topology
1M1KN 1K8AN 2QA4M 3CPWL 1Q82N 3CCUM 1QVGL 1K9MN 1M90N 3G6EM 1YITM 3CCSM 1VQ4M 2QEXM 3CCJM 1YJWM 3G4SM 1KC8N 1VQ9M 3CC4M 3CCQM 1VQMM 1VQ6M 3CC2M 3CCEM 2OTJM 2OTLM 1Q7YN 1VQ8M 1Q86N 3CMEM 3CCLM 1VQ7M 1VQNM 1VQOM 1YJ9M 3CD6M 3I55M 1W2BL 1Q81N 1JJ2L 1VQ5M 1S72M 3CXCL 3I56M 3CCMM 3CMAM 1YI2M 1N8RN 3CCRM 1YJNM 1YIJM 1YHQM 3OW2L 1VQLM 1NJIN 1VQKM 3G71M 1VQPM 3CCVM 1KD1N 1KQSL 3CC7M 1QVFL 1K73N
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M1K N;  1K8A N;  2QA4 M;  3CPW L;  1Q82 N;  3CCU M;  1QVG L;  1K9M N;  1M90 N;  3G6E M;  1YIT M;  3CCS M;  1VQ4 M;  2QEX M;  3CCJ M;  1YJW M;  3G4S M;  1KC8 N;  1VQ9 M;  3CC4 M;  3CCQ M;  1VQM M;  1VQ6 M;  3CC2 M;  3CCE M;  2OTJ M;  2OTL M;  1Q7Y N;  1VQ8 M;  1Q86 N;  3CME M;  3CCL M;  1VQ7 M;  1VQN M;  1VQO M;  1YJ9 M;  3CD6 M;  3I55 M;  1W2B L;  1Q81 N;  1JJ2 L;  1VQ5 M;  1S72 M;  3CXC L;  3I56 M;  3CCM M;  3CMA M;  1YI2 M;  1N8R N;  3CCR M;  1YJN M;  1YIJ M;  1YHQ M;  3OW2 L;  1VQL M;  1NJI N;  1VQK M;  3G71 M;  1VQP M;  3CCV M;  1KD1 N;  1KQS L;  3CC7 M;  1QVF L;  1K73 N; 
#chains in the Genus database with same CATH topology
 1M1K N;  1K8A N;  2QA4 M;  3CPW L;  1Q82 N;  3CCU M;  1QVG L;  1K9M N;  1M90 N;  3G6E M;  1YIT M;  3CCS M;  1VQ4 M;  2QEX M;  3CCJ M;  1YJW M;  3G4S M;  1KC8 N;  1VQ9 M;  3CC4 M;  3CCQ M;  1VQM M;  1VQ6 M;  3CC2 M;  3CCE M;  2OTJ M;  2OTL M;  1Q7Y N;  1VQ8 M;  1Q86 N;  3CME M;  3CCL M;  1VQ7 M;  1VQN M;  1VQO M;  1YJ9 M;  3CD6 M;  3I55 M;  1W2B L;  1Q81 N;  1JJ2 L;  1VQ5 M;  1S72 M;  3CXC L;  3I56 M;  3CCM M;  3CMA M;  1YI2 M;  1N8R N;  3CCR M;  1YJN M;  1YIJ M;  1YHQ M;  3OW2 L;  1VQL M;  1NJI N;  1VQK M;  3G71 M;  1VQP M;  3CCV M;  1KD1 N;  1KQS L;  3CC7 M;  1QVF L;  1K73 N; 
#chains in the Genus database with same CATH homology
 1M1K N;  1K8A N;  2QA4 M;  3CPW L;  1Q82 N;  3CCU M;  1QVG L;  1K9M N;  1M90 N;  3G6E M;  1YIT M;  3CCS M;  1VQ4 M;  2QEX M;  3CCJ M;  1YJW M;  3G4S M;  1KC8 N;  1VQ9 M;  3CC4 M;  3CCQ M;  1VQM M;  1VQ6 M;  3CC2 M;  3CCE M;  2OTJ M;  2OTL M;  1Q7Y N;  1VQ8 M;  1Q86 N;  3CME M;  3CCL M;  1VQ7 M;  1VQN M;  1VQO M;  1YJ9 M;  3CD6 M;  3I55 M;  1W2B L;  1Q81 N;  1JJ2 L;  1VQ5 M;  1S72 M;  3CXC L;  3I56 M;  3CCM M;  3CMA M;  1YI2 M;  1N8R N;  3CCR M;  1YJN M;  1YIJ M;  1YHQ M;  3OW2 L;  1VQL M;  1NJI N;  1VQK M;  3G71 M;  1VQP M;  3CCV M;  1KD1 N;  1KQS L;  3CC7 M;  1QVF L;  1K73 N; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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