3CCJC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 58
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccjC00
1VQLC 1YITC 1N8RE 1VQ4C 1Q82E 3CMAC 3J7YF 2OTJC 1KD1E 2OTLC 1YJWC 3CCQC 1VQMC 3I55C 1YIJC 1W2BC 3CCLC 1YJ9C 3CCRC 3CCUC 3CCVC 1Q81E 3CCJC 4V19F 1VQ9C 1K73E 1DMGA 1QVGC 1M90E 1KC8E 1JJ2C 3I56C 3CCMC 2QA4C 1Q86E 1QVFC 3CC2C 3OW2C 1KQSC 3CPWC 3CCSC 1Q7YE 3CMEC 1VQNC 1VQOC 2QEXC 3CC7C 1M1KE 1VQ8C 1YJNC 1S72C 3CXCC 1VQ7C 1VQ6C 3CD6C 1YI2C 1K9ME 3CCEC 3G4SC 1YHQC 3G6EC 1VQKC 1NJIE 3G71C 3CC4C 5DM7C 1VQPC 1VQ5C 1K8AE
chains in the Genus database with same CATH superfamily
1VQLC 1YITC 1N8RE 1VQ4C 1Q82E 3CMAC 3J7YF 2OTJC 1KD1E 2OTLC 1YJWC 3CCQC 1VQMC 3I55C 1YIJC 1W2BC 3CCLC 1YJ9C 3CCRC 3CCUC 3CCVC 1Q81E 3CCJC 4V19F 1VQ9C 1K73E 1DMGA 1QVGC 1M90E 1KC8E 1JJ2C 3I56C 3CCMC 2QA4C 1Q86E 1QVFC 3CC2C 3OW2C 1KQSC 3CPWC 3CCSC 1Q7YE 3CMEC 1VQNC 1VQOC 2QEXC 3CC7C 1M1KE 1VQ8C 1YJNC 1S72C 3CXCC 1VQ7C 1VQ6C 3CD6C 1YI2C 1K9ME 3CCEC 3G4SC 1YHQC 3G6EC 1VQKC 1NJIE 3G71C 3CC4C 5DM7C 1VQPC 1VQ5C 1K8AE
chains in the Genus database with same CATH topology
1VQLC 1YITC 1N8RE 1VQ4C 1Q82E 3CMAC 3J7YF 2OTJC 1KD1E 2OTLC 1YJWC 3CCQC 1VQMC 3I55C 1YIJC 1W2BC 3CCLC 1YJ9C 3CCRC 3CCUC 3CCVC 1Q81E 3CCJC 4V19F 1VQ9C 1K73E 1DMGA 1QVGC 1M90E 1KC8E 1JJ2C 3I56C 3CCMC 2QA4C 1Q86E 1QVFC 3CC2C 3OW2C 1KQSC 3CPWC 3CCSC 1Q7YE 3CMEC 1VQNC 1VQOC 2QEXC 3CC7C 1M1KE 1VQ8C 1YJNC 1S72C 3CXCC 1VQ7C 1VQ6C 3CD6C 1YI2C 1K9ME 3CCEC 3G4SC 1YHQC 3G6EC 1VQKC 1NJIE 3G71C 3CC4C 5DM7C 1VQPC 1VQ5C 1K8AE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQL C;  1YIT C;  1N8R E;  1VQ4 C;  1Q82 E;  3CMA C;  3J7Y F;  2OTJ C;  1KD1 E;  2OTL C;  1YJW C;  3CCQ C;  1VQM C;  3I55 C;  1YIJ C;  1W2B C;  3CCL C;  1YJ9 C;  3CCR C;  3CCU C;  3CCV C;  1Q81 E;  3CCJ C;  4V19 F;  1VQ9 C;  1K73 E;  1DMG A;  1QVG C;  1M90 E;  1KC8 E;  1JJ2 C;  3I56 C;  3CCM C;  2QA4 C;  1Q86 E;  1QVF C;  3CC2 C;  3OW2 C;  1KQS C;  3CPW C;  3CCS C;  1Q7Y E;  3CME C;  1VQN C;  1VQO C;  2QEX C;  3CC7 C;  1M1K E;  1VQ8 C;  1YJN C;  1S72 C;  3CXC C;  1VQ7 C;  1VQ6 C;  3CD6 C;  1YI2 C;  1K9M E;  3CCE C;  3G4S C;  1YHQ C;  3G6E C;  1VQK C;  1NJI E;  3G71 C;  3CC4 C;  5DM7 C;  1VQP C;  1VQ5 C;  1K8A E; 
#chains in the Genus database with same CATH topology
 1VQL C;  1YIT C;  1N8R E;  1VQ4 C;  1Q82 E;  3CMA C;  3J7Y F;  2OTJ C;  1KD1 E;  2OTL C;  1YJW C;  3CCQ C;  1VQM C;  3I55 C;  1YIJ C;  1W2B C;  3CCL C;  1YJ9 C;  3CCR C;  3CCU C;  3CCV C;  1Q81 E;  3CCJ C;  4V19 F;  1VQ9 C;  1K73 E;  1DMG A;  1QVG C;  1M90 E;  1KC8 E;  1JJ2 C;  3I56 C;  3CCM C;  2QA4 C;  1Q86 E;  1QVF C;  3CC2 C;  3OW2 C;  1KQS C;  3CPW C;  3CCS C;  1Q7Y E;  3CME C;  1VQN C;  1VQO C;  2QEX C;  3CC7 C;  1M1K E;  1VQ8 C;  1YJN C;  1S72 C;  3CXC C;  1VQ7 C;  1VQ6 C;  3CD6 C;  1YI2 C;  1K9M E;  3CCE C;  3G4S C;  1YHQ C;  3G6E C;  1VQK C;  1NJI E;  3G71 C;  3CC4 C;  5DM7 C;  1VQP C;  1VQ5 C;  1K8A E; 
#chains in the Genus database with same CATH homology
 1VQL C;  1YIT C;  1N8R E;  1VQ4 C;  1Q82 E;  3CMA C;  3J7Y F;  2OTJ C;  1KD1 E;  2OTL C;  1YJW C;  3CCQ C;  1VQM C;  3I55 C;  1YIJ C;  1W2B C;  3CCL C;  1YJ9 C;  3CCR C;  3CCU C;  3CCV C;  1Q81 E;  3CCJ C;  4V19 F;  1VQ9 C;  1K73 E;  1DMG A;  1QVG C;  1M90 E;  1KC8 E;  1JJ2 C;  3I56 C;  3CCM C;  2QA4 C;  1Q86 E;  1QVF C;  3CC2 C;  3OW2 C;  1KQS C;  3CPW C;  3CCS C;  1Q7Y E;  3CME C;  1VQN C;  1VQO C;  2QEX C;  3CC7 C;  1M1K E;  1VQ8 C;  1YJN C;  1S72 C;  3CXC C;  1VQ7 C;  1VQ6 C;  3CD6 C;  1YI2 C;  1K9M E;  3CCE C;  3G4S C;  1YHQ C;  3G6E C;  1VQK C;  1NJI E;  3G71 C;  3CC4 C;  5DM7 C;  1VQP C;  1VQ5 C;  1K8A E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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