3CCLM

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
194
structure length
194
Chain Sequence
ARSAYSYIRDAWKNPGDGQLAELQWQRQQEWRNEGAVERIERPTRLDKARSQGYKAKQGVIVARVSVRKGSARKRRHKAGRRSKRQGVTRITRRKDIQRVAEERASRTFPNLRVLNSYSVGQDGRQKWHEVILIDPNHPAIQNDDDLSWICADDQADRVFRGLTGAGRRNRGLSGKGKGSEKTRPSLRSNGGKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 57
structure length 194
sequence length 194
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00827 Ribosomal_L15e Ribosomal L15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1120.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal protein L15e Ribosomal protein l15e 3cclM00
1NJIN 1VQPM 1VQOM 2OTLM 3CCUM 1JJ2L 1YJNM 1K9MN 3G6EM 3OW2L 1N8RN 1KC8N 1M1KN 1K8AN 1YJ9M 1VQ7M 3CCVM 1QVFL 1K73N 1VQ6M 3CCJM 1Q82N 2OTJM 1S72M 3CMAM 1KD1N 3CC2M 1VQNM 3I56M 3I55M 3CCRM 2QA4M 1VQMM 1QVGL 1Q81N 3CD6M 1W2BL 1VQKM 1YIJM 3CCEM 3CPWL 1VQ8M 3CXCL 3CMEM 1VQ9M 3CCMM 1Q86N 3CC7M 1VQ4M 1YHQM 3CCSM 3G4SM 3G71M 1VQLM 1KQSL 1Q7YN 1YITM 3CCQM 1M90N 1YJWM 1YI2M 1VQ5M 3CC4M 2QEXM 3CCLM
chains in the Genus database with same CATH superfamily
1NJIN 1VQPM 1VQOM 2OTLM 3CCUM 1JJ2L 1YJNM 1K9MN 3G6EM 3OW2L 1N8RN 1KC8N 1M1KN 1K8AN 1YJ9M 1VQ7M 3CCVM 1QVFL 1K73N 1VQ6M 3CCJM 1Q82N 2OTJM 1S72M 3CMAM 1KD1N 3CC2M 1VQNM 3I56M 3I55M 3CCRM 2QA4M 1VQMM 1QVGL 1Q81N 3CD6M 1W2BL 1VQKM 1YIJM 3CCEM 3CPWL 1VQ8M 3CXCL 3CMEM 1VQ9M 3CCMM 1Q86N 3CC7M 1VQ4M 1YHQM 3CCSM 3G4SM 3G71M 1VQLM 1KQSL 1Q7YN 1YITM 3CCQM 1M90N 1YJWM 1YI2M 1VQ5M 3CC4M 2QEXM 3CCLM
chains in the Genus database with same CATH topology
1NJIN 1VQPM 1VQOM 2OTLM 3CCUM 1JJ2L 1YJNM 1K9MN 3G6EM 3OW2L 1N8RN 1KC8N 1M1KN 1K8AN 1YJ9M 1VQ7M 3CCVM 1QVFL 1K73N 1VQ6M 3CCJM 1Q82N 2OTJM 1S72M 3CMAM 1KD1N 3CC2M 1VQNM 3I56M 3I55M 3CCRM 2QA4M 1VQMM 1QVGL 1Q81N 3CD6M 1W2BL 1VQKM 1YIJM 3CCEM 3CPWL 1VQ8M 3CXCL 3CMEM 1VQ9M 3CCMM 1Q86N 3CC7M 1VQ4M 1YHQM 3CCSM 3G4SM 3G71M 1VQLM 1KQSL 1Q7YN 1YITM 3CCQM 1M90N 1YJWM 1YI2M 1VQ5M 3CC4M 2QEXM 3CCLM
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NJI N;  1VQP M;  1VQO M;  2OTL M;  3CCU M;  1JJ2 L;  1YJN M;  1K9M N;  3G6E M;  3OW2 L;  1N8R N;  1KC8 N;  1M1K N;  1K8A N;  1YJ9 M;  1VQ7 M;  3CCV M;  1QVF L;  1K73 N;  1VQ6 M;  3CCJ M;  1Q82 N;  2OTJ M;  1S72 M;  3CMA M;  1KD1 N;  3CC2 M;  1VQN M;  3I56 M;  3I55 M;  3CCR M;  2QA4 M;  1VQM M;  1QVG L;  1Q81 N;  3CD6 M;  1W2B L;  1VQK M;  1YIJ M;  3CCE M;  3CPW L;  1VQ8 M;  3CXC L;  3CME M;  1VQ9 M;  3CCM M;  1Q86 N;  3CC7 M;  1VQ4 M;  1YHQ M;  3CCS M;  3G4S M;  3G71 M;  1VQL M;  1KQS L;  1Q7Y N;  1YIT M;  3CCQ M;  1M90 N;  1YJW M;  1YI2 M;  1VQ5 M;  3CC4 M;  2QEX M;  3CCL M; 
#chains in the Genus database with same CATH topology
 1NJI N;  1VQP M;  1VQO M;  2OTL M;  3CCU M;  1JJ2 L;  1YJN M;  1K9M N;  3G6E M;  3OW2 L;  1N8R N;  1KC8 N;  1M1K N;  1K8A N;  1YJ9 M;  1VQ7 M;  3CCV M;  1QVF L;  1K73 N;  1VQ6 M;  3CCJ M;  1Q82 N;  2OTJ M;  1S72 M;  3CMA M;  1KD1 N;  3CC2 M;  1VQN M;  3I56 M;  3I55 M;  3CCR M;  2QA4 M;  1VQM M;  1QVG L;  1Q81 N;  3CD6 M;  1W2B L;  1VQK M;  1YIJ M;  3CCE M;  3CPW L;  1VQ8 M;  3CXC L;  3CME M;  1VQ9 M;  3CCM M;  1Q86 N;  3CC7 M;  1VQ4 M;  1YHQ M;  3CCS M;  3G4S M;  3G71 M;  1VQL M;  1KQS L;  1Q7Y N;  1YIT M;  3CCQ M;  1M90 N;  1YJW M;  1YI2 M;  1VQ5 M;  3CC4 M;  2QEX M;  3CCL M; 
#chains in the Genus database with same CATH homology
 1NJI N;  1VQP M;  1VQO M;  2OTL M;  3CCU M;  1JJ2 L;  1YJN M;  1K9M N;  3G6E M;  3OW2 L;  1N8R N;  1KC8 N;  1M1K N;  1K8A N;  1YJ9 M;  1VQ7 M;  3CCV M;  1QVF L;  1K73 N;  1VQ6 M;  3CCJ M;  1Q82 N;  2OTJ M;  1S72 M;  3CMA M;  1KD1 N;  3CC2 M;  1VQN M;  3I56 M;  3I55 M;  3CCR M;  2QA4 M;  1VQM M;  1QVG L;  1Q81 N;  3CD6 M;  1W2B L;  1VQK M;  1YIJ M;  3CCE M;  3CPW L;  1VQ8 M;  3CXC L;  3CME M;  1VQ9 M;  3CCM M;  1Q86 N;  3CC7 M;  1VQ4 M;  1YHQ M;  3CCS M;  3G4S M;  3G71 M;  1VQL M;  1KQS L;  1Q7Y N;  1YIT M;  3CCQ M;  1M90 N;  1YJW M;  1YI2 M;  1VQ5 M;  3CC4 M;  2QEX M;  3CCL M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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