3CCM2

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
49
structure length
46
Chain Sequence
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDRRNHKRRHWRRNDTDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 10
structure length 46
sequence length 49
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
2 PF00832 Ribosomal_L39 Ribosomal L39 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1620.10 Mainly Alpha Orthogonal Bundle Atp Synthase Epsilon Chain; Chain: I; Ribosomal protein L39e 3ccm200
3CC42 3CD62 3CCM2 1M1K3 1S722 1YIJ2 1VQ52 3CCQ2 3CCE2 3CPW1 1Q813 1VQ72 3G712 1VQM2 2OTL2 3CC22 1KC83 1K8A3 1KD13 3G4S2 3CCJ2 1VQ92 3OW21 1K733 1YIT2 2OTJ2 3CCU2 3CME2 2QEX2 1M903 3CCL2 1YJN2 1VQP2 1NJI3 3I562 1YJW2 1N8R3 1VQ62 3CC72 3CXC1 1K9M3 3CMA2 1VQ82 1W2B1 1VQK2 1YHQ2 1JJ21 1VQL2 1Q7Y3 1KQS1 1VQN2 1VQO2 3I552 1YI22 1VQ42 3CCR2 3CCV2 2QA42 1YJ92 3G6E2 1QVF1 1QVG1 1Q823 3CCS2 1Q863
chains in the Genus database with same CATH superfamily
3CC42 3CD62 3CCM2 1M1K3 2WSSI 1S722 1YIJ2 2WPDI 1VQ52 4YXWI 3CCE2 3CPW1 3CCQ2 1VQ72 1Q813 3G712 1VQM2 2OTL2 3CC22 1KC83 1K8A3 1KD13 3G4S2 3CCJ2 1VQ92 3OW21 1K733 1YIT2 2OTJ2 3CCU2 3CME2 2QEX2 1M903 3CCL2 1YJN2 1VQP2 1NJI3 3I562 3ZIAI 1YJW2 1N8R3 2XNDI 1VQ62 3CC72 3CXC1 1K9M3 3CMA2 1VQ82 1W2B1 1VQK2 1YHQ2 1JJ21 1VQL2 3OFNI 1Q7Y3 1KQS1 1VQN2 1VQO2 2XOKI 2V7QI 3I552 1E79I 1YI22 1VQ42 3CCR2 3CCV2 2QA42 1YJ92 3G6E2 1QVF1 1QVG1 1Q823 3CCS2 1Q863
chains in the Genus database with same CATH topology
3CC42 3CD62 3CCM2 1M1K3 1S722 1YIJ2 1VQ52 3CCQ2 3CCE2 3CPW1 1Q813 1VQ72 3G712 1VQM2 2OTL2 3CC22 1KC83 1K8A3 1KD13 3G4S2 3CCJ2 1VQ92 3OW21 1K733 1YIT2 2OTJ2 3CCU2 3CME2 2QEX2 1M903 3CCL2 1YJN2 1VQP2 1NJI3 3I562 1YJW2 1N8R3 1VQ62 3CC72 3CXC1 1K9M3 3CMA2 1VQ82 1W2B1 1VQK2 1YHQ2 1JJ21 1VQL2 1Q7Y3 1KQS1 1VQN2 1VQO2 3I552 1YI22 1VQ42 3CCR2 3CCV2 2QA42 1YJ92 3G6E2 1QVF1 1QVG1 1Q823 3CCS2 1Q863
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CC4 2;  3CD6 2;  3CCM 2;  1M1K 3;  1S72 2;  1YIJ 2;  1VQ5 2;  3CCQ 2;  3CCE 2;  3CPW 1;  1Q81 3;  1VQ7 2;  3G71 2;  1VQM 2;  2OTL 2;  3CC2 2;  1KC8 3;  1K8A 3;  1KD1 3;  3G4S 2;  3CCJ 2;  1VQ9 2;  3OW2 1;  1K73 3;  1YIT 2;  2OTJ 2;  3CCU 2;  3CME 2;  2QEX 2;  1M90 3;  3CCL 2;  1YJN 2;  1VQP 2;  1NJI 3;  3I56 2;  1YJW 2;  1N8R 3;  1VQ6 2;  3CC7 2;  3CXC 1;  1K9M 3;  3CMA 2;  1VQ8 2;  1W2B 1;  1VQK 2;  1YHQ 2;  1JJ2 1;  1VQL 2;  1Q7Y 3;  1KQS 1;  1VQN 2;  1VQO 2;  3I55 2;  1YI2 2;  1VQ4 2;  3CCR 2;  3CCV 2;  2QA4 2;  1YJ9 2;  3G6E 2;  1QVF 1;  1QVG 1;  1Q82 3;  3CCS 2;  1Q86 3; 
#chains in the Genus database with same CATH topology
 3CC4 2;  3CD6 2;  3CCM 2;  1M1K 3;  2WSS I;  1S72 2;  1YIJ 2;  2WPD I;  1VQ5 2;  4YXW I;  3CCE 2;  3CPW 1;  3CCQ 2;  1VQ7 2;  1Q81 3;  3G71 2;  1VQM 2;  2OTL 2;  3CC2 2;  1KC8 3;  1K8A 3;  1KD1 3;  3G4S 2;  3CCJ 2;  1VQ9 2;  3OW2 1;  1K73 3;  1YIT 2;  2OTJ 2;  3CCU 2;  3CME 2;  2QEX 2;  1M90 3;  3CCL 2;  1YJN 2;  1VQP 2;  1NJI 3;  3I56 2;  3ZIA I;  1YJW 2;  1N8R 3;  2XND I;  1VQ6 2;  3CC7 2;  3CXC 1;  1K9M 3;  3CMA 2;  1VQ8 2;  1W2B 1;  1VQK 2;  1YHQ 2;  1JJ2 1;  1VQL 2;  3OFN I;  1Q7Y 3;  1KQS 1;  1VQN 2;  1VQO 2;  2XOK I;  2V7Q I;  3I55 2;  1E79 I;  1YI2 2;  1VQ4 2;  3CCR 2;  3CCV 2;  2QA4 2;  1YJ9 2;  3G6E 2;  1QVF 1;  1QVG 1;  1Q82 3;  3CCS 2;  1Q86 3; 
#chains in the Genus database with same CATH homology
 3CC4 2;  3CD6 2;  3CCM 2;  1M1K 3;  1S72 2;  1YIJ 2;  1VQ5 2;  3CCQ 2;  3CCE 2;  3CPW 1;  1Q81 3;  1VQ7 2;  3G71 2;  1VQM 2;  2OTL 2;  3CC2 2;  1KC8 3;  1K8A 3;  1KD1 3;  3G4S 2;  3CCJ 2;  1VQ9 2;  3OW2 1;  1K73 3;  1YIT 2;  2OTJ 2;  3CCU 2;  3CME 2;  2QEX 2;  1M90 3;  3CCL 2;  1YJN 2;  1VQP 2;  1NJI 3;  3I56 2;  1YJW 2;  1N8R 3;  1VQ6 2;  3CC7 2;  3CXC 1;  1K9M 3;  3CMA 2;  1VQ8 2;  1W2B 1;  1VQK 2;  1YHQ 2;  1JJ2 1;  1VQL 2;  1Q7Y 3;  1KQS 1;  1VQN 2;  1VQO 2;  3I55 2;  1YI2 2;  1VQ4 2;  3CCR 2;  3CCV 2;  2QA4 2;  1YJ9 2;  3G6E 2;  1QVF 1;  1QVG 1;  1Q82 3;  3CCS 2;  1Q86 3; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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