3CCMC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 61
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccmC00
1YI2C 1VQOC 3CC7C 1YIJC 1NJIE 3CCVC 1VQKC 1VQPC 3CCUC 3I55C 1VQLC 3CCEC 1Q81E 1VQ4C 3CCLC 3CC4C 1VQMC 1VQ6C 2OTJC 1K8AE 3CCRC 1YITC 1W2BC 1QVGC 3CPWC 3CD6C 3CC2C 2OTLC 1VQ8C 1VQ9C 1VQ7C 1Q86E 1KC8E 3CCMC 1K9ME 1M90E 3J7YF 3OW2C 1Q7YE 1VQNC 2QA4C 3G71C 3CCJC 3G4SC 1KD1E 1QVFC 1S72C 1N8RE 1K73E 1VQ5C 3CMEC 3CCSC 3I56C 5DM7C 3CCQC 1KQSC 4V19F 2QEXC 1YJ9C 1Q82E 1YHQC 1YJNC 3CXCC 1YJWC 3CMAC 1DMGA 3G6EC 1M1KE 1JJ2C
chains in the Genus database with same CATH superfamily
1YI2C 1VQOC 3CC7C 1YIJC 1NJIE 3CCVC 1VQKC 1VQPC 3CCUC 3I55C 1VQLC 3CCEC 1Q81E 1VQ4C 3CCLC 3CC4C 1VQMC 1VQ6C 2OTJC 1K8AE 3CCRC 1YITC 1W2BC 1QVGC 3CPWC 3CD6C 3CC2C 2OTLC 1VQ8C 1VQ9C 1VQ7C 1Q86E 1KC8E 3CCMC 1K9ME 1M90E 3J7YF 3OW2C 1Q7YE 1VQNC 2QA4C 3G71C 3CCJC 3G4SC 1KD1E 1QVFC 1S72C 1N8RE 1K73E 1VQ5C 3CMEC 3CCSC 3I56C 5DM7C 3CCQC 1KQSC 4V19F 2QEXC 1YJ9C 1Q82E 1YHQC 1YJNC 3CXCC 1YJWC 3CMAC 1DMGA 3G6EC 1M1KE 1JJ2C
chains in the Genus database with same CATH topology
1YI2C 1VQOC 3CC7C 1YIJC 1NJIE 3CCVC 1VQKC 1VQPC 3CCUC 3I55C 1VQLC 3CCEC 1Q81E 1VQ4C 3CCLC 3CC4C 1VQMC 1VQ6C 2OTJC 1K8AE 3CCRC 1YITC 1W2BC 1QVGC 3CPWC 3CD6C 3CC2C 2OTLC 1VQ8C 1VQ9C 1VQ7C 1Q86E 1KC8E 3CCMC 1K9ME 1M90E 3J7YF 3OW2C 1Q7YE 1VQNC 2QA4C 3G71C 3CCJC 3G4SC 1KD1E 1QVFC 1S72C 1N8RE 1K73E 1VQ5C 3CMEC 3CCSC 3I56C 5DM7C 3CCQC 1KQSC 4V19F 2QEXC 1YJ9C 1Q82E 1YHQC 1YJNC 3CXCC 1YJWC 3CMAC 1DMGA 3G6EC 1M1KE 1JJ2C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YI2 C;  1VQO C;  3CC7 C;  1YIJ C;  1NJI E;  3CCV C;  1VQK C;  1VQP C;  3CCU C;  3I55 C;  1VQL C;  3CCE C;  1Q81 E;  1VQ4 C;  3CCL C;  3CC4 C;  1VQM C;  1VQ6 C;  2OTJ C;  1K8A E;  3CCR C;  1YIT C;  1W2B C;  1QVG C;  3CPW C;  3CD6 C;  3CC2 C;  2OTL C;  1VQ8 C;  1VQ9 C;  1VQ7 C;  1Q86 E;  1KC8 E;  3CCM C;  1K9M E;  1M90 E;  3J7Y F;  3OW2 C;  1Q7Y E;  1VQN C;  2QA4 C;  3G71 C;  3CCJ C;  3G4S C;  1KD1 E;  1QVF C;  1S72 C;  1N8R E;  1K73 E;  1VQ5 C;  3CME C;  3CCS C;  3I56 C;  5DM7 C;  3CCQ C;  1KQS C;  4V19 F;  2QEX C;  1YJ9 C;  1Q82 E;  1YHQ C;  1YJN C;  3CXC C;  1YJW C;  3CMA C;  1DMG A;  3G6E C;  1M1K E;  1JJ2 C; 
#chains in the Genus database with same CATH topology
 1YI2 C;  1VQO C;  3CC7 C;  1YIJ C;  1NJI E;  3CCV C;  1VQK C;  1VQP C;  3CCU C;  3I55 C;  1VQL C;  3CCE C;  1Q81 E;  1VQ4 C;  3CCL C;  3CC4 C;  1VQM C;  1VQ6 C;  2OTJ C;  1K8A E;  3CCR C;  1YIT C;  1W2B C;  1QVG C;  3CPW C;  3CD6 C;  3CC2 C;  2OTL C;  1VQ8 C;  1VQ9 C;  1VQ7 C;  1Q86 E;  1KC8 E;  3CCM C;  1K9M E;  1M90 E;  3J7Y F;  3OW2 C;  1Q7Y E;  1VQN C;  2QA4 C;  3G71 C;  3CCJ C;  3G4S C;  1KD1 E;  1QVF C;  1S72 C;  1N8R E;  1K73 E;  1VQ5 C;  3CME C;  3CCS C;  3I56 C;  5DM7 C;  3CCQ C;  1KQS C;  4V19 F;  2QEX C;  1YJ9 C;  1Q82 E;  1YHQ C;  1YJN C;  3CXC C;  1YJW C;  3CMA C;  1DMG A;  3G6E C;  1M1K E;  1JJ2 C; 
#chains in the Genus database with same CATH homology
 1YI2 C;  1VQO C;  3CC7 C;  1YIJ C;  1NJI E;  3CCV C;  1VQK C;  1VQP C;  3CCU C;  3I55 C;  1VQL C;  3CCE C;  1Q81 E;  1VQ4 C;  3CCL C;  3CC4 C;  1VQM C;  1VQ6 C;  2OTJ C;  1K8A E;  3CCR C;  1YIT C;  1W2B C;  1QVG C;  3CPW C;  3CD6 C;  3CC2 C;  2OTL C;  1VQ8 C;  1VQ9 C;  1VQ7 C;  1Q86 E;  1KC8 E;  3CCM C;  1K9M E;  1M90 E;  3J7Y F;  3OW2 C;  1Q7Y E;  1VQN C;  2QA4 C;  3G71 C;  3CCJ C;  3G4S C;  1KD1 E;  1QVF C;  1S72 C;  1N8R E;  1K73 E;  1VQ5 C;  3CME C;  3CCS C;  3I56 C;  5DM7 C;  3CCQ C;  1KQS C;  4V19 F;  2QEX C;  1YJ9 C;  1Q82 E;  1YHQ C;  1YJN C;  3CXC C;  1YJW C;  3CMA C;  1DMG A;  3G6E C;  1M1K E;  1JJ2 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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