3CCQC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 61
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccqC00
3CCSC 1VQ8C 2OTJC 1VQ9C 3CD6C 5DM7C 1YIJC 1S72C 1JJ2C 1QVGC 3CC7C 3CCUC 3I55C 3G6EC 1Q7YE 1Q81E 1K9ME 1W2BC 3CCMC 1VQ4C 1VQPC 1VQ5C 1NJIE 3CMAC 3CCVC 1N8RE 1KC8E 1YJ9C 4V19F 1YITC 3J7YF 3OW2C 1Q82E 3CCQC 1Q86E 1K8AE 1VQKC 3CC4C 1M90E 2OTLC 1VQLC 3G4SC 3CMEC 1QVFC 1K73E 1KQSC 1DMGA 1VQ7C 3CCJC 3G71C 3CXCC 2QA4C 3CCRC 1VQNC 3I56C 1M1KE 1VQMC 2QEXC 1YHQC 3CPWC 1YI2C 3CC2C 3CCLC 1YJWC 1VQOC 1VQ6C 3CCEC 1KD1E 1YJNC
chains in the Genus database with same CATH superfamily
3CCSC 1VQ8C 2OTJC 1VQ9C 3CD6C 5DM7C 1YIJC 1S72C 1JJ2C 1QVGC 3CC7C 3CCUC 3I55C 3G6EC 1Q7YE 1Q81E 1K9ME 1W2BC 3CCMC 1VQ4C 1VQPC 1VQ5C 1NJIE 3CMAC 3CCVC 1N8RE 1KC8E 1YJ9C 4V19F 1YITC 3J7YF 3OW2C 1Q82E 3CCQC 1Q86E 1K8AE 1VQKC 3CC4C 1M90E 2OTLC 1VQLC 3G4SC 3CMEC 1QVFC 1K73E 1KQSC 1DMGA 1VQ7C 3CCJC 3G71C 3CXCC 2QA4C 3CCRC 1VQNC 3I56C 1M1KE 1VQMC 2QEXC 1YHQC 3CPWC 1YI2C 3CC2C 3CCLC 1YJWC 1VQOC 1VQ6C 3CCEC 1KD1E 1YJNC
chains in the Genus database with same CATH topology
3CCSC 1VQ8C 2OTJC 1VQ9C 3CD6C 5DM7C 1YIJC 1S72C 1JJ2C 1QVGC 3CC7C 3CCUC 3I55C 3G6EC 1Q7YE 1Q81E 1K9ME 1W2BC 3CCMC 1VQ4C 1VQPC 1VQ5C 1NJIE 3CMAC 3CCVC 1N8RE 1KC8E 1YJ9C 4V19F 1YITC 3J7YF 3OW2C 1Q82E 3CCQC 1Q86E 1K8AE 1VQKC 3CC4C 1M90E 2OTLC 1VQLC 3G4SC 3CMEC 1QVFC 1K73E 1KQSC 1DMGA 1VQ7C 3CCJC 3G71C 3CXCC 2QA4C 3CCRC 1VQNC 3I56C 1M1KE 1VQMC 2QEXC 1YHQC 3CPWC 1YI2C 3CC2C 3CCLC 1YJWC 1VQOC 1VQ6C 3CCEC 1KD1E 1YJNC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCS C;  1VQ8 C;  2OTJ C;  1VQ9 C;  3CD6 C;  5DM7 C;  1YIJ C;  1S72 C;  1JJ2 C;  1QVG C;  3CC7 C;  3CCU C;  3I55 C;  3G6E C;  1Q7Y E;  1Q81 E;  1K9M E;  1W2B C;  3CCM C;  1VQ4 C;  1VQP C;  1VQ5 C;  1NJI E;  3CMA C;  3CCV C;  1N8R E;  1KC8 E;  1YJ9 C;  4V19 F;  1YIT C;  3J7Y F;  3OW2 C;  1Q82 E;  3CCQ C;  1Q86 E;  1K8A E;  1VQK C;  3CC4 C;  1M90 E;  2OTL C;  1VQL C;  3G4S C;  3CME C;  1QVF C;  1K73 E;  1KQS C;  1DMG A;  1VQ7 C;  3CCJ C;  3G71 C;  3CXC C;  2QA4 C;  3CCR C;  1VQN C;  3I56 C;  1M1K E;  1VQM C;  2QEX C;  1YHQ C;  3CPW C;  1YI2 C;  3CC2 C;  3CCL C;  1YJW C;  1VQO C;  1VQ6 C;  3CCE C;  1KD1 E;  1YJN C; 
#chains in the Genus database with same CATH topology
 3CCS C;  1VQ8 C;  2OTJ C;  1VQ9 C;  3CD6 C;  5DM7 C;  1YIJ C;  1S72 C;  1JJ2 C;  1QVG C;  3CC7 C;  3CCU C;  3I55 C;  3G6E C;  1Q7Y E;  1Q81 E;  1K9M E;  1W2B C;  3CCM C;  1VQ4 C;  1VQP C;  1VQ5 C;  1NJI E;  3CMA C;  3CCV C;  1N8R E;  1KC8 E;  1YJ9 C;  4V19 F;  1YIT C;  3J7Y F;  3OW2 C;  1Q82 E;  3CCQ C;  1Q86 E;  1K8A E;  1VQK C;  3CC4 C;  1M90 E;  2OTL C;  1VQL C;  3G4S C;  3CME C;  1QVF C;  1K73 E;  1KQS C;  1DMG A;  1VQ7 C;  3CCJ C;  3G71 C;  3CXC C;  2QA4 C;  3CCR C;  1VQN C;  3I56 C;  1M1K E;  1VQM C;  2QEX C;  1YHQ C;  3CPW C;  1YI2 C;  3CC2 C;  3CCL C;  1YJW C;  1VQO C;  1VQ6 C;  3CCE C;  1KD1 E;  1YJN C; 
#chains in the Genus database with same CATH homology
 3CCS C;  1VQ8 C;  2OTJ C;  1VQ9 C;  3CD6 C;  5DM7 C;  1YIJ C;  1S72 C;  1JJ2 C;  1QVG C;  3CC7 C;  3CCU C;  3I55 C;  3G6E C;  1Q7Y E;  1Q81 E;  1K9M E;  1W2B C;  3CCM C;  1VQ4 C;  1VQP C;  1VQ5 C;  1NJI E;  3CMA C;  3CCV C;  1N8R E;  1KC8 E;  1YJ9 C;  4V19 F;  1YIT C;  3J7Y F;  3OW2 C;  1Q82 E;  3CCQ C;  1Q86 E;  1K8A E;  1VQK C;  3CC4 C;  1M90 E;  2OTL C;  1VQL C;  3G4S C;  3CME C;  1QVF C;  1K73 E;  1KQS C;  1DMG A;  1VQ7 C;  3CCJ C;  3G71 C;  3CXC C;  2QA4 C;  3CCR C;  1VQN C;  3I56 C;  1M1K E;  1VQM C;  2QEX C;  1YHQ C;  3CPW C;  1YI2 C;  3CC2 C;  3CCL C;  1YJW C;  1VQO C;  1VQ6 C;  3CCE C;  1KD1 E;  1YJN C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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