3CCQM

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
194
structure length
194
Chain Sequence
ARSAYSYIRDAWKNPGDGQLAELQWQRQQEWRNEGAVERIERPTRLDKARSQGYKAKQGVIVARVSVRKGSARKRRHKAGRRSKRQGVTRITRRKDIQRVAEERASRTFPNLRVLNSYSVGQDGRQKWHEVILIDPNHPAIQNDDDLSWICADDQADRVFRGLTGAGRRNRGLSGKGKGSEKTRPSLRSNGGKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 56
structure length 194
sequence length 194
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00827 Ribosomal_L15e Ribosomal L15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1120.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal protein L15e Ribosomal protein l15e 3ccqM00
3G6EM 1M1KN 3OW2L 1VQMM 2QA4M 1NJIN 3CCLM 1KQSL 3CCJM 3CCRM 1M90N 1YJWM 3G71M 3CCQM 3CCEM 1K9MN 1K8AN 3CC4M 1VQOM 1Q81N 1QVGL 1YITM 3CCMM 3CCUM 3CC7M 1VQ6M 1Q82N 1KD1N 1VQ4M 3CC2M 1VQLM 1VQ7M 1VQKM 1VQ8M 1YHQM 1N8RN 1VQNM 1YI2M 3CXCL 3CCSM 3CCVM 3I55M 1YIJM 2OTLM 1YJNM 3CPWL 3G4SM 1YJ9M 3CMAM 1Q7YN 1Q86N 1VQ5M 1QVFL 3CD6M 2OTJM 3CMEM 1VQ9M 1W2BL 1JJ2L 3I56M 1VQPM 1K73N 1S72M 2QEXM 1KC8N
chains in the Genus database with same CATH superfamily
3G6EM 1M1KN 3OW2L 1VQMM 2QA4M 1NJIN 3CCLM 1KQSL 3CCJM 3CCRM 1M90N 1YJWM 3G71M 3CCQM 3CCEM 1K9MN 1K8AN 3CC4M 1VQOM 1Q81N 1QVGL 1YITM 3CCMM 3CCUM 3CC7M 1VQ6M 1Q82N 1KD1N 1VQ4M 3CC2M 1VQLM 1VQ7M 1VQKM 1VQ8M 1YHQM 1N8RN 1VQNM 1YI2M 3CXCL 3CCSM 3CCVM 3I55M 1YIJM 2OTLM 1YJNM 3CPWL 3G4SM 1YJ9M 3CMAM 1Q7YN 1Q86N 1VQ5M 1QVFL 3CD6M 2OTJM 3CMEM 1VQ9M 1W2BL 1JJ2L 3I56M 1VQPM 1K73N 1S72M 2QEXM 1KC8N
chains in the Genus database with same CATH topology
3G6EM 1M1KN 3OW2L 1VQMM 2QA4M 1NJIN 3CCLM 1KQSL 3CCJM 3CCRM 1M90N 1YJWM 3G71M 3CCQM 3CCEM 1K9MN 1K8AN 3CC4M 1VQOM 1Q81N 1QVGL 1YITM 3CCMM 3CCUM 3CC7M 1VQ6M 1Q82N 1KD1N 1VQ4M 3CC2M 1VQLM 1VQ7M 1VQKM 1VQ8M 1YHQM 1N8RN 1VQNM 1YI2M 3CXCL 3CCSM 3CCVM 3I55M 1YIJM 2OTLM 1YJNM 3CPWL 3G4SM 1YJ9M 3CMAM 1Q7YN 1Q86N 1VQ5M 1QVFL 3CD6M 2OTJM 3CMEM 1VQ9M 1W2BL 1JJ2L 3I56M 1VQPM 1K73N 1S72M 2QEXM 1KC8N
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G6E M;  1M1K N;  3OW2 L;  1VQM M;  2QA4 M;  1NJI N;  3CCL M;  1KQS L;  3CCJ M;  3CCR M;  1M90 N;  1YJW M;  3G71 M;  3CCQ M;  3CCE M;  1K9M N;  1K8A N;  3CC4 M;  1VQO M;  1Q81 N;  1QVG L;  1YIT M;  3CCM M;  3CCU M;  3CC7 M;  1VQ6 M;  1Q82 N;  1KD1 N;  1VQ4 M;  3CC2 M;  1VQL M;  1VQ7 M;  1VQK M;  1VQ8 M;  1YHQ M;  1N8R N;  1VQN M;  1YI2 M;  3CXC L;  3CCS M;  3CCV M;  3I55 M;  1YIJ M;  2OTL M;  1YJN M;  3CPW L;  3G4S M;  1YJ9 M;  3CMA M;  1Q7Y N;  1Q86 N;  1VQ5 M;  1QVF L;  3CD6 M;  2OTJ M;  3CME M;  1VQ9 M;  1W2B L;  1JJ2 L;  3I56 M;  1VQP M;  1K73 N;  1S72 M;  2QEX M;  1KC8 N; 
#chains in the Genus database with same CATH topology
 3G6E M;  1M1K N;  3OW2 L;  1VQM M;  2QA4 M;  1NJI N;  3CCL M;  1KQS L;  3CCJ M;  3CCR M;  1M90 N;  1YJW M;  3G71 M;  3CCQ M;  3CCE M;  1K9M N;  1K8A N;  3CC4 M;  1VQO M;  1Q81 N;  1QVG L;  1YIT M;  3CCM M;  3CCU M;  3CC7 M;  1VQ6 M;  1Q82 N;  1KD1 N;  1VQ4 M;  3CC2 M;  1VQL M;  1VQ7 M;  1VQK M;  1VQ8 M;  1YHQ M;  1N8R N;  1VQN M;  1YI2 M;  3CXC L;  3CCS M;  3CCV M;  3I55 M;  1YIJ M;  2OTL M;  1YJN M;  3CPW L;  3G4S M;  1YJ9 M;  3CMA M;  1Q7Y N;  1Q86 N;  1VQ5 M;  1QVF L;  3CD6 M;  2OTJ M;  3CME M;  1VQ9 M;  1W2B L;  1JJ2 L;  3I56 M;  1VQP M;  1K73 N;  1S72 M;  2QEX M;  1KC8 N; 
#chains in the Genus database with same CATH homology
 3G6E M;  1M1K N;  3OW2 L;  1VQM M;  2QA4 M;  1NJI N;  3CCL M;  1KQS L;  3CCJ M;  3CCR M;  1M90 N;  1YJW M;  3G71 M;  3CCQ M;  3CCE M;  1K9M N;  1K8A N;  3CC4 M;  1VQO M;  1Q81 N;  1QVG L;  1YIT M;  3CCM M;  3CCU M;  3CC7 M;  1VQ6 M;  1Q82 N;  1KD1 N;  1VQ4 M;  3CC2 M;  1VQL M;  1VQ7 M;  1VQK M;  1VQ8 M;  1YHQ M;  1N8R N;  1VQN M;  1YI2 M;  3CXC L;  3CCS M;  3CCV M;  3I55 M;  1YIJ M;  2OTL M;  1YJN M;  3CPW L;  3G4S M;  1YJ9 M;  3CMA M;  1Q7Y N;  1Q86 N;  1VQ5 M;  1QVF L;  3CD6 M;  2OTJ M;  3CME M;  1VQ9 M;  1W2B L;  1JJ2 L;  3I56 M;  1VQP M;  1K73 N;  1S72 M;  2QEX M;  1KC8 N; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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