3CCR2

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
49
structure length
46
Chain Sequence
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDRRNHKRRHWRRNDTDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 12
structure length 46
sequence length 49
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
2 PF00832 Ribosomal_L39 Ribosomal L39 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1620.10 Mainly Alpha Orthogonal Bundle Atp Synthase Epsilon Chain; Chain: I; Ribosomal protein L39e 3ccr200
3CCJ2 3I552 3CCE2 3I562 1NJI3 1S722 1KQS1 2QEX2 3CCM2 1YJ92 1Q823 1K9M3 1M1K3 1JJ21 1K8A3 1VQ72 3CD62 1M903 1VQ82 1QVG1 1VQ42 3CC22 3CPW1 3CXC1 3CCR2 2OTJ2 1YIJ2 3CC72 1YIT2 3G6E2 1VQP2 2QA42 1KC83 3CMA2 1VQ92 1Q863 3CCU2 1YJW2 1YI22 1VQL2 1YHQ2 3OW21 3G712 3CCV2 1N8R3 1Q813 1VQK2 1QVF1 1Q7Y3 1KD13 1W2B1 3CME2 3CCL2 3CCS2 1VQO2 1K733 3CC42 3CCQ2 1YJN2 2OTL2 1VQ62 1VQN2 3G4S2 1VQ52 1VQM2
chains in the Genus database with same CATH superfamily
3CCJ2 3I552 3CCE2 3I562 1NJI3 1S722 4YXWI 1KQS1 2WPDI 2QEX2 3CCM2 1YJ92 1Q823 1K9M3 1M1K3 3OFNI 1VQ72 1K8A3 1M903 1JJ21 1QVG1 1VQ82 3CD62 1VQ42 3CC22 3CPW1 3CXC1 3CCR2 2OTJ2 1YIJ2 3CC72 1YIT2 3G6E2 2XNDI 2QA42 1VQP2 3CMA2 1VQ92 1Q863 3CCU2 1YJW2 1YI22 1KC83 1YHQ2 1VQL2 3OW21 3G712 3CCV2 1N8R3 1Q813 3ZIAI 1VQK2 1QVF1 1Q7Y3 1KD13 2V7QI 1W2B1 3CME2 3CCL2 3CCS2 1VQO2 1K733 1E79I 3CC42 3CCQ2 2WSSI 1YJN2 2XOKI 2OTL2 1VQ62 1VQN2 3G4S2 1VQ52 1VQM2
chains in the Genus database with same CATH topology
3CCJ2 3I552 3CCE2 3I562 1NJI3 1S722 1KQS1 2QEX2 3CCM2 1YJ92 1Q823 1K9M3 1M1K3 1JJ21 1K8A3 1VQ72 3CD62 1M903 1VQ82 1QVG1 1VQ42 3CC22 3CPW1 3CXC1 3CCR2 2OTJ2 1YIJ2 3CC72 1YIT2 3G6E2 1VQP2 2QA42 1KC83 3CMA2 1VQ92 1Q863 3CCU2 1YJW2 1YI22 1VQL2 1YHQ2 3OW21 3G712 3CCV2 1N8R3 1Q813 1VQK2 1QVF1 1Q7Y3 1KD13 1W2B1 3CME2 3CCL2 3CCS2 1VQO2 1K733 3CC42 3CCQ2 1YJN2 2OTL2 1VQ62 1VQN2 3G4S2 1VQ52 1VQM2
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCJ 2;  3I55 2;  3CCE 2;  3I56 2;  1NJI 3;  1S72 2;  1KQS 1;  2QEX 2;  3CCM 2;  1YJ9 2;  1Q82 3;  1K9M 3;  1M1K 3;  1JJ2 1;  1K8A 3;  1VQ7 2;  3CD6 2;  1M90 3;  1VQ8 2;  1QVG 1;  1VQ4 2;  3CC2 2;  3CPW 1;  3CXC 1;  3CCR 2;  2OTJ 2;  1YIJ 2;  3CC7 2;  1YIT 2;  3G6E 2;  1VQP 2;  2QA4 2;  1KC8 3;  3CMA 2;  1VQ9 2;  1Q86 3;  3CCU 2;  1YJW 2;  1YI2 2;  1VQL 2;  1YHQ 2;  3OW2 1;  3G71 2;  3CCV 2;  1N8R 3;  1Q81 3;  1VQK 2;  1QVF 1;  1Q7Y 3;  1KD1 3;  1W2B 1;  3CME 2;  3CCL 2;  3CCS 2;  1VQO 2;  1K73 3;  3CC4 2;  3CCQ 2;  1YJN 2;  2OTL 2;  1VQ6 2;  1VQN 2;  3G4S 2;  1VQ5 2;  1VQM 2; 
#chains in the Genus database with same CATH topology
 3CCJ 2;  3I55 2;  3CCE 2;  3I56 2;  1NJI 3;  1S72 2;  4YXW I;  1KQS 1;  2WPD I;  2QEX 2;  3CCM 2;  1YJ9 2;  1Q82 3;  1K9M 3;  1M1K 3;  3OFN I;  1VQ7 2;  1K8A 3;  1M90 3;  1JJ2 1;  1QVG 1;  1VQ8 2;  3CD6 2;  1VQ4 2;  3CC2 2;  3CPW 1;  3CXC 1;  3CCR 2;  2OTJ 2;  1YIJ 2;  3CC7 2;  1YIT 2;  3G6E 2;  2XND I;  2QA4 2;  1VQP 2;  3CMA 2;  1VQ9 2;  1Q86 3;  3CCU 2;  1YJW 2;  1YI2 2;  1KC8 3;  1YHQ 2;  1VQL 2;  3OW2 1;  3G71 2;  3CCV 2;  1N8R 3;  1Q81 3;  3ZIA I;  1VQK 2;  1QVF 1;  1Q7Y 3;  1KD1 3;  2V7Q I;  1W2B 1;  3CME 2;  3CCL 2;  3CCS 2;  1VQO 2;  1K73 3;  1E79 I;  3CC4 2;  3CCQ 2;  2WSS I;  1YJN 2;  2XOK I;  2OTL 2;  1VQ6 2;  1VQN 2;  3G4S 2;  1VQ5 2;  1VQM 2; 
#chains in the Genus database with same CATH homology
 3CCJ 2;  3I55 2;  3CCE 2;  3I56 2;  1NJI 3;  1S72 2;  1KQS 1;  2QEX 2;  3CCM 2;  1YJ9 2;  1Q82 3;  1K9M 3;  1M1K 3;  1JJ2 1;  1K8A 3;  1VQ7 2;  3CD6 2;  1M90 3;  1VQ8 2;  1QVG 1;  1VQ4 2;  3CC2 2;  3CPW 1;  3CXC 1;  3CCR 2;  2OTJ 2;  1YIJ 2;  3CC7 2;  1YIT 2;  3G6E 2;  1VQP 2;  2QA4 2;  1KC8 3;  3CMA 2;  1VQ9 2;  1Q86 3;  3CCU 2;  1YJW 2;  1YI2 2;  1VQL 2;  1YHQ 2;  3OW2 1;  3G71 2;  3CCV 2;  1N8R 3;  1Q81 3;  1VQK 2;  1QVF 1;  1Q7Y 3;  1KD1 3;  1W2B 1;  3CME 2;  3CCL 2;  3CCS 2;  1VQO 2;  1K73 3;  3CC4 2;  3CCQ 2;  1YJN 2;  2OTL 2;  1VQ6 2;  1VQN 2;  3G4S 2;  1VQ5 2;  1VQM 2; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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