3CCRC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 59
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccrC00
1VQ9C 3CCEC 3CMAC 1VQPC 1YITC 3I56C 3CC7C 3OW2C 1YJWC 1N8RE 1Q7YE 1Q86E 1KC8E 1YJ9C 1QVGC 2OTJC 1YIJC 3CCJC 1VQ5C 2QEXC 2QA4C 1Q81E 3CC2C 3CCRC 1VQKC 3CMEC 1VQMC 1VQ4C 1K8AE 4V19F 3G71C 3CC4C 1YJNC 1K9ME 1VQNC 1S72C 3G4SC 3CCQC 1M90E 2OTLC 1YI2C 1QVFC 5DM7C 1KD1E 3CCMC 3CCUC 1VQ8C 1Q82E 1VQ7C 3CD6C 1KQSC 3CXCC 3G6EC 1VQOC 1K73E 3CCLC 3I55C 3J7YF 1YHQC 1M1KE 1DMGA 1NJIE 1JJ2C 3CCVC 3CPWC 1VQ6C 1W2BC 1VQLC 3CCSC
chains in the Genus database with same CATH superfamily
1VQ9C 3CCEC 3CMAC 1VQPC 1YITC 3I56C 3CC7C 3OW2C 1YJWC 1N8RE 1Q7YE 1Q86E 1KC8E 1YJ9C 1QVGC 2OTJC 1YIJC 3CCJC 1VQ5C 2QEXC 2QA4C 1Q81E 3CC2C 3CCRC 1VQKC 3CMEC 1VQMC 1VQ4C 1K8AE 4V19F 3G71C 3CC4C 1YJNC 1K9ME 1VQNC 1S72C 3G4SC 3CCQC 1M90E 2OTLC 1YI2C 1QVFC 5DM7C 1KD1E 3CCMC 3CCUC 1VQ8C 1Q82E 1VQ7C 3CD6C 1KQSC 3CXCC 3G6EC 1VQOC 1K73E 3CCLC 3I55C 3J7YF 1YHQC 1M1KE 1DMGA 1NJIE 1JJ2C 3CCVC 3CPWC 1VQ6C 1W2BC 1VQLC 3CCSC
chains in the Genus database with same CATH topology
1VQ9C 3CCEC 3CMAC 1VQPC 1YITC 3I56C 3CC7C 3OW2C 1YJWC 1N8RE 1Q7YE 1Q86E 1KC8E 1YJ9C 1QVGC 2OTJC 1YIJC 3CCJC 1VQ5C 2QEXC 2QA4C 1Q81E 3CC2C 3CCRC 1VQKC 3CMEC 1VQMC 1VQ4C 1K8AE 4V19F 3G71C 3CC4C 1YJNC 1K9ME 1VQNC 1S72C 3G4SC 3CCQC 1M90E 2OTLC 1YI2C 1QVFC 5DM7C 1KD1E 3CCMC 3CCUC 1VQ8C 1Q82E 1VQ7C 3CD6C 1KQSC 3CXCC 3G6EC 1VQOC 1K73E 3CCLC 3I55C 3J7YF 1YHQC 1M1KE 1DMGA 1NJIE 1JJ2C 3CCVC 3CPWC 1VQ6C 1W2BC 1VQLC 3CCSC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ9 C;  3CCE C;  3CMA C;  1VQP C;  1YIT C;  3I56 C;  3CC7 C;  3OW2 C;  1YJW C;  1N8R E;  1Q7Y E;  1Q86 E;  1KC8 E;  1YJ9 C;  1QVG C;  2OTJ C;  1YIJ C;  3CCJ C;  1VQ5 C;  2QEX C;  2QA4 C;  1Q81 E;  3CC2 C;  3CCR C;  1VQK C;  3CME C;  1VQM C;  1VQ4 C;  1K8A E;  4V19 F;  3G71 C;  3CC4 C;  1YJN C;  1K9M E;  1VQN C;  1S72 C;  3G4S C;  3CCQ C;  1M90 E;  2OTL C;  1YI2 C;  1QVF C;  5DM7 C;  1KD1 E;  3CCM C;  3CCU C;  1VQ8 C;  1Q82 E;  1VQ7 C;  3CD6 C;  1KQS C;  3CXC C;  3G6E C;  1VQO C;  1K73 E;  3CCL C;  3I55 C;  3J7Y F;  1YHQ C;  1M1K E;  1DMG A;  1NJI E;  1JJ2 C;  3CCV C;  3CPW C;  1VQ6 C;  1W2B C;  1VQL C;  3CCS C; 
#chains in the Genus database with same CATH topology
 1VQ9 C;  3CCE C;  3CMA C;  1VQP C;  1YIT C;  3I56 C;  3CC7 C;  3OW2 C;  1YJW C;  1N8R E;  1Q7Y E;  1Q86 E;  1KC8 E;  1YJ9 C;  1QVG C;  2OTJ C;  1YIJ C;  3CCJ C;  1VQ5 C;  2QEX C;  2QA4 C;  1Q81 E;  3CC2 C;  3CCR C;  1VQK C;  3CME C;  1VQM C;  1VQ4 C;  1K8A E;  4V19 F;  3G71 C;  3CC4 C;  1YJN C;  1K9M E;  1VQN C;  1S72 C;  3G4S C;  3CCQ C;  1M90 E;  2OTL C;  1YI2 C;  1QVF C;  5DM7 C;  1KD1 E;  3CCM C;  3CCU C;  1VQ8 C;  1Q82 E;  1VQ7 C;  3CD6 C;  1KQS C;  3CXC C;  3G6E C;  1VQO C;  1K73 E;  3CCL C;  3I55 C;  3J7Y F;  1YHQ C;  1M1K E;  1DMG A;  1NJI E;  1JJ2 C;  3CCV C;  3CPW C;  1VQ6 C;  1W2B C;  1VQL C;  3CCS C; 
#chains in the Genus database with same CATH homology
 1VQ9 C;  3CCE C;  3CMA C;  1VQP C;  1YIT C;  3I56 C;  3CC7 C;  3OW2 C;  1YJW C;  1N8R E;  1Q7Y E;  1Q86 E;  1KC8 E;  1YJ9 C;  1QVG C;  2OTJ C;  1YIJ C;  3CCJ C;  1VQ5 C;  2QEX C;  2QA4 C;  1Q81 E;  3CC2 C;  3CCR C;  1VQK C;  3CME C;  1VQM C;  1VQ4 C;  1K8A E;  4V19 F;  3G71 C;  3CC4 C;  1YJN C;  1K9M E;  1VQN C;  1S72 C;  3G4S C;  3CCQ C;  1M90 E;  2OTL C;  1YI2 C;  1QVF C;  5DM7 C;  1KD1 E;  3CCM C;  3CCU C;  1VQ8 C;  1Q82 E;  1VQ7 C;  3CD6 C;  1KQS C;  3CXC C;  3G6E C;  1VQO C;  1K73 E;  3CCL C;  3I55 C;  3J7Y F;  1YHQ C;  1M1K E;  1DMG A;  1NJI E;  1JJ2 C;  3CCV C;  3CPW C;  1VQ6 C;  1W2B C;  1VQL C;  3CCS C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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