3CCRM

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
194
structure length
194
Chain Sequence
ARSAYSYIRDAWKNPGDGQLAELQWQRQQEWRNEGAVERIERPTRLDKARSQGYKAKQGVIVARVSVRKGSARKRRHKAGRRSKRQGVTRITRRKDIQRVAEERASRTFPNLRVLNSYSVGQDGRQKWHEVILIDPNHPAIQNDDDLSWICADDQADRVFRGLTGAGRRNRGLSGKGKGSEKTRPSLRSNGGKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 50
structure length 194
sequence length 194
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00827 Ribosomal_L15e Ribosomal L15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1120.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal protein L15e Ribosomal protein l15e 3ccrM00
1NJIN 1VQOM 1KQSL 1VQ4M 1QVGL 3CMEM 1YJWM 3G71M 1M90N 1Q86N 1VQ5M 3CXCL 3CCMM 3CCQM 2OTJM 3G6EM 1S72M 3CCUM 1M1KN 1VQNM 3CCEM 1VQPM 3I56M 1Q7YN 1QVFL 3CPWL 2QA4M 3CC4M 3CD6M 3CCSM 1YIJM 1VQLM 1YITM 3G4SM 3CCVM 1VQ8M 1VQKM 1KD1N 3CC7M 1VQ6M 3CCJM 3I55M 1N8RN 1KC8N 1YJ9M 1YJNM 3CCLM 3CMAM 2QEXM 1K8AN 3OW2L 1VQ7M 1YHQM 1K9MN 1VQ9M 1K73N 1Q81N 1VQMM 1W2BL 1Q82N 2OTLM 3CC2M 1JJ2L 3CCRM 1YI2M
chains in the Genus database with same CATH superfamily
1NJIN 1VQOM 1KQSL 1VQ4M 1QVGL 3CMEM 1YJWM 3G71M 1M90N 1Q86N 1VQ5M 3CXCL 3CCMM 3CCQM 2OTJM 3G6EM 1S72M 3CCUM 1M1KN 1VQNM 3CCEM 1VQPM 3I56M 1Q7YN 1QVFL 3CPWL 2QA4M 3CC4M 3CD6M 3CCSM 1YIJM 1VQLM 1YITM 3G4SM 3CCVM 1VQ8M 1VQKM 1KD1N 3CC7M 1VQ6M 3CCJM 3I55M 1N8RN 1KC8N 1YJ9M 1YJNM 3CCLM 3CMAM 2QEXM 1K8AN 3OW2L 1VQ7M 1YHQM 1K9MN 1VQ9M 1K73N 1Q81N 1VQMM 1W2BL 1Q82N 2OTLM 3CC2M 1JJ2L 3CCRM 1YI2M
chains in the Genus database with same CATH topology
1NJIN 1VQOM 1KQSL 1VQ4M 1QVGL 3CMEM 1YJWM 3G71M 1M90N 1Q86N 1VQ5M 3CXCL 3CCMM 3CCQM 2OTJM 3G6EM 1S72M 3CCUM 1M1KN 1VQNM 3CCEM 1VQPM 3I56M 1Q7YN 1QVFL 3CPWL 2QA4M 3CC4M 3CD6M 3CCSM 1YIJM 1VQLM 1YITM 3G4SM 3CCVM 1VQ8M 1VQKM 1KD1N 3CC7M 1VQ6M 3CCJM 3I55M 1N8RN 1KC8N 1YJ9M 1YJNM 3CCLM 3CMAM 2QEXM 1K8AN 3OW2L 1VQ7M 1YHQM 1K9MN 1VQ9M 1K73N 1Q81N 1VQMM 1W2BL 1Q82N 2OTLM 3CC2M 1JJ2L 3CCRM 1YI2M
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NJI N;  1VQO M;  1KQS L;  1VQ4 M;  1QVG L;  3CME M;  1YJW M;  3G71 M;  1M90 N;  1Q86 N;  1VQ5 M;  3CXC L;  3CCM M;  3CCQ M;  2OTJ M;  3G6E M;  1S72 M;  3CCU M;  1M1K N;  1VQN M;  3CCE M;  1VQP M;  3I56 M;  1Q7Y N;  1QVF L;  3CPW L;  2QA4 M;  3CC4 M;  3CD6 M;  3CCS M;  1YIJ M;  1VQL M;  1YIT M;  3G4S M;  3CCV M;  1VQ8 M;  1VQK M;  1KD1 N;  3CC7 M;  1VQ6 M;  3CCJ M;  3I55 M;  1N8R N;  1KC8 N;  1YJ9 M;  1YJN M;  3CCL M;  3CMA M;  2QEX M;  1K8A N;  3OW2 L;  1VQ7 M;  1YHQ M;  1K9M N;  1VQ9 M;  1K73 N;  1Q81 N;  1VQM M;  1W2B L;  1Q82 N;  2OTL M;  3CC2 M;  1JJ2 L;  3CCR M;  1YI2 M; 
#chains in the Genus database with same CATH topology
 1NJI N;  1VQO M;  1KQS L;  1VQ4 M;  1QVG L;  3CME M;  1YJW M;  3G71 M;  1M90 N;  1Q86 N;  1VQ5 M;  3CXC L;  3CCM M;  3CCQ M;  2OTJ M;  3G6E M;  1S72 M;  3CCU M;  1M1K N;  1VQN M;  3CCE M;  1VQP M;  3I56 M;  1Q7Y N;  1QVF L;  3CPW L;  2QA4 M;  3CC4 M;  3CD6 M;  3CCS M;  1YIJ M;  1VQL M;  1YIT M;  3G4S M;  3CCV M;  1VQ8 M;  1VQK M;  1KD1 N;  3CC7 M;  1VQ6 M;  3CCJ M;  3I55 M;  1N8R N;  1KC8 N;  1YJ9 M;  1YJN M;  3CCL M;  3CMA M;  2QEX M;  1K8A N;  3OW2 L;  1VQ7 M;  1YHQ M;  1K9M N;  1VQ9 M;  1K73 N;  1Q81 N;  1VQM M;  1W2B L;  1Q82 N;  2OTL M;  3CC2 M;  1JJ2 L;  3CCR M;  1YI2 M; 
#chains in the Genus database with same CATH homology
 1NJI N;  1VQO M;  1KQS L;  1VQ4 M;  1QVG L;  3CME M;  1YJW M;  3G71 M;  1M90 N;  1Q86 N;  1VQ5 M;  3CXC L;  3CCM M;  3CCQ M;  2OTJ M;  3G6E M;  1S72 M;  3CCU M;  1M1K N;  1VQN M;  3CCE M;  1VQP M;  3I56 M;  1Q7Y N;  1QVF L;  3CPW L;  2QA4 M;  3CC4 M;  3CD6 M;  3CCS M;  1YIJ M;  1VQL M;  1YIT M;  3G4S M;  3CCV M;  1VQ8 M;  1VQK M;  1KD1 N;  3CC7 M;  1VQ6 M;  3CCJ M;  3I55 M;  1N8R N;  1KC8 N;  1YJ9 M;  1YJN M;  3CCL M;  3CMA M;  2QEX M;  1K8A N;  3OW2 L;  1VQ7 M;  1YHQ M;  1K9M N;  1VQ9 M;  1K73 N;  1Q81 N;  1VQM M;  1W2B L;  1Q82 N;  2OTL M;  3CC2 M;  1JJ2 L;  3CCR M;  1YI2 M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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