3CCSC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 55
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccsC00
1DMGA 3CC2C 1Q82E 1NJIE 3OW2C 4V19F 1VQLC 1VQ4C 1VQKC 3CMAC 3CC7C 1VQ9C 1S72C 1Q7YE 3CD6C 2OTLC 1YIJC 1K9ME 3I55C 3CCUC 3CXCC 1K8AE 1Q81E 1YHQC 3CCVC 1VQ6C 3CCSC 1YJ9C 1YJWC 3CCMC 1VQ5C 1QVGC 3G71C 3CMEC 1YITC 1K73E 3CPWC 1QVFC 1M90E 2QEXC 1KC8E 1VQNC 3J7YF 1YI2C 1VQ7C 3CC4C 1KD1E 3CCQC 1W2BC 3CCEC 1N8RE 3I56C 1YJNC 1M1KE 2QA4C 3G6EC 1Q86E 1JJ2C 1VQPC 1KQSC 1VQOC 1VQMC 5DM7C 3CCLC 1VQ8C 2OTJC 3CCJC 3G4SC 3CCRC
chains in the Genus database with same CATH superfamily
1DMGA 3CC2C 1Q82E 1NJIE 3OW2C 4V19F 1VQLC 1VQ4C 1VQKC 3CMAC 3CC7C 1VQ9C 1S72C 1Q7YE 3CD6C 2OTLC 1YIJC 1K9ME 3I55C 3CCUC 3CXCC 1K8AE 1Q81E 1YHQC 3CCVC 1VQ6C 3CCSC 1YJ9C 1YJWC 3CCMC 1VQ5C 1QVGC 3G71C 3CMEC 1YITC 1K73E 3CPWC 1QVFC 1M90E 2QEXC 1KC8E 1VQNC 3J7YF 1YI2C 1VQ7C 3CC4C 1KD1E 3CCQC 1W2BC 3CCEC 1N8RE 3I56C 1YJNC 1M1KE 2QA4C 3G6EC 1Q86E 1JJ2C 1VQPC 1KQSC 1VQOC 1VQMC 5DM7C 3CCLC 1VQ8C 2OTJC 3CCJC 3G4SC 3CCRC
chains in the Genus database with same CATH topology
1DMGA 3CC2C 1Q82E 1NJIE 3OW2C 4V19F 1VQLC 1VQ4C 1VQKC 3CMAC 3CC7C 1VQ9C 1S72C 1Q7YE 3CD6C 2OTLC 1YIJC 1K9ME 3I55C 3CCUC 3CXCC 1K8AE 1Q81E 1YHQC 3CCVC 1VQ6C 3CCSC 1YJ9C 1YJWC 3CCMC 1VQ5C 1QVGC 3G71C 3CMEC 1YITC 1K73E 3CPWC 1QVFC 1M90E 2QEXC 1KC8E 1VQNC 3J7YF 1YI2C 1VQ7C 3CC4C 1KD1E 3CCQC 1W2BC 3CCEC 1N8RE 3I56C 1YJNC 1M1KE 2QA4C 3G6EC 1Q86E 1JJ2C 1VQPC 1KQSC 1VQOC 1VQMC 5DM7C 3CCLC 1VQ8C 2OTJC 3CCJC 3G4SC 3CCRC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DMG A;  3CC2 C;  1Q82 E;  1NJI E;  3OW2 C;  4V19 F;  1VQL C;  1VQ4 C;  1VQK C;  3CMA C;  3CC7 C;  1VQ9 C;  1S72 C;  1Q7Y E;  3CD6 C;  2OTL C;  1YIJ C;  1K9M E;  3I55 C;  3CCU C;  3CXC C;  1K8A E;  1Q81 E;  1YHQ C;  3CCV C;  1VQ6 C;  3CCS C;  1YJ9 C;  1YJW C;  3CCM C;  1VQ5 C;  1QVG C;  3G71 C;  3CME C;  1YIT C;  1K73 E;  3CPW C;  1QVF C;  1M90 E;  2QEX C;  1KC8 E;  1VQN C;  3J7Y F;  1YI2 C;  1VQ7 C;  3CC4 C;  1KD1 E;  3CCQ C;  1W2B C;  3CCE C;  1N8R E;  3I56 C;  1YJN C;  1M1K E;  2QA4 C;  3G6E C;  1Q86 E;  1JJ2 C;  1VQP C;  1KQS C;  1VQO C;  1VQM C;  5DM7 C;  3CCL C;  1VQ8 C;  2OTJ C;  3CCJ C;  3G4S C;  3CCR C; 
#chains in the Genus database with same CATH topology
 1DMG A;  3CC2 C;  1Q82 E;  1NJI E;  3OW2 C;  4V19 F;  1VQL C;  1VQ4 C;  1VQK C;  3CMA C;  3CC7 C;  1VQ9 C;  1S72 C;  1Q7Y E;  3CD6 C;  2OTL C;  1YIJ C;  1K9M E;  3I55 C;  3CCU C;  3CXC C;  1K8A E;  1Q81 E;  1YHQ C;  3CCV C;  1VQ6 C;  3CCS C;  1YJ9 C;  1YJW C;  3CCM C;  1VQ5 C;  1QVG C;  3G71 C;  3CME C;  1YIT C;  1K73 E;  3CPW C;  1QVF C;  1M90 E;  2QEX C;  1KC8 E;  1VQN C;  3J7Y F;  1YI2 C;  1VQ7 C;  3CC4 C;  1KD1 E;  3CCQ C;  1W2B C;  3CCE C;  1N8R E;  3I56 C;  1YJN C;  1M1K E;  2QA4 C;  3G6E C;  1Q86 E;  1JJ2 C;  1VQP C;  1KQS C;  1VQO C;  1VQM C;  5DM7 C;  3CCL C;  1VQ8 C;  2OTJ C;  3CCJ C;  3G4S C;  3CCR C; 
#chains in the Genus database with same CATH homology
 1DMG A;  3CC2 C;  1Q82 E;  1NJI E;  3OW2 C;  4V19 F;  1VQL C;  1VQ4 C;  1VQK C;  3CMA C;  3CC7 C;  1VQ9 C;  1S72 C;  1Q7Y E;  3CD6 C;  2OTL C;  1YIJ C;  1K9M E;  3I55 C;  3CCU C;  3CXC C;  1K8A E;  1Q81 E;  1YHQ C;  3CCV C;  1VQ6 C;  3CCS C;  1YJ9 C;  1YJW C;  3CCM C;  1VQ5 C;  1QVG C;  3G71 C;  3CME C;  1YIT C;  1K73 E;  3CPW C;  1QVF C;  1M90 E;  2QEX C;  1KC8 E;  1VQN C;  3J7Y F;  1YI2 C;  1VQ7 C;  3CC4 C;  1KD1 E;  3CCQ C;  1W2B C;  3CCE C;  1N8R E;  3I56 C;  1YJN C;  1M1K E;  2QA4 C;  3G6E C;  1Q86 E;  1JJ2 C;  1VQP C;  1KQS C;  1VQO C;  1VQM C;  5DM7 C;  3CCL C;  1VQ8 C;  2OTJ C;  3CCJ C;  3G4S C;  3CCR C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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