3CCUC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 64
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccuC00
3CCRC 3CCSC 1VQLC 2QEXC 1YI2C 1Q86E 1Q82E 1VQMC 3CCQC 1QVGC 1JJ2C 3CCMC 1VQ6C 3CXCC 3CCEC 1NJIE 1K9ME 1YJWC 3CPWC 3G4SC 2OTLC 1YHQC 1Q81E 1K8AE 3G71C 3CCUC 1YITC 1QVFC 3CCJC 1VQPC 1VQ4C 1W2BC 1M90E 3CC7C 3CCLC 2QA4C 1YJ9C 1DMGA 3G6EC 3CD6C 1N8RE 1KC8E 1VQKC 4V19F 3CCVC 3CC4C 1YJNC 1KD1E 3CC2C 1VQNC 2OTJC 1Q7YE 1VQ5C 1M1KE 3I55C 1KQSC 5DM7C 1VQ8C 3I56C 3CMAC 3J7YF 1YIJC 3CMEC 3OW2C 1VQ9C 1VQOC 1K73E 1VQ7C 1S72C
chains in the Genus database with same CATH superfamily
3CCRC 3CCSC 1VQLC 2QEXC 1YI2C 1Q86E 1Q82E 1VQMC 3CCQC 1QVGC 1JJ2C 3CCMC 1VQ6C 3CXCC 3CCEC 1NJIE 1K9ME 1YJWC 3CPWC 3G4SC 2OTLC 1YHQC 1Q81E 1K8AE 3G71C 3CCUC 1YITC 1QVFC 3CCJC 1VQPC 1VQ4C 1W2BC 1M90E 3CC7C 3CCLC 2QA4C 1YJ9C 1DMGA 3G6EC 3CD6C 1N8RE 1KC8E 1VQKC 4V19F 3CCVC 3CC4C 1YJNC 1KD1E 3CC2C 1VQNC 2OTJC 1Q7YE 1VQ5C 1M1KE 3I55C 1KQSC 5DM7C 1VQ8C 3I56C 3CMAC 3J7YF 1YIJC 3CMEC 3OW2C 1VQ9C 1VQOC 1K73E 1VQ7C 1S72C
chains in the Genus database with same CATH topology
3CCRC 3CCSC 1VQLC 2QEXC 1YI2C 1Q86E 1Q82E 1VQMC 3CCQC 1QVGC 1JJ2C 3CCMC 1VQ6C 3CXCC 3CCEC 1NJIE 1K9ME 1YJWC 3CPWC 3G4SC 2OTLC 1YHQC 1Q81E 1K8AE 3G71C 3CCUC 1YITC 1QVFC 3CCJC 1VQPC 1VQ4C 1W2BC 1M90E 3CC7C 3CCLC 2QA4C 1YJ9C 1DMGA 3G6EC 3CD6C 1N8RE 1KC8E 1VQKC 4V19F 3CCVC 3CC4C 1YJNC 1KD1E 3CC2C 1VQNC 2OTJC 1Q7YE 1VQ5C 1M1KE 3I55C 1KQSC 5DM7C 1VQ8C 3I56C 3CMAC 3J7YF 1YIJC 3CMEC 3OW2C 1VQ9C 1VQOC 1K73E 1VQ7C 1S72C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCR C;  3CCS C;  1VQL C;  2QEX C;  1YI2 C;  1Q86 E;  1Q82 E;  1VQM C;  3CCQ C;  1QVG C;  1JJ2 C;  3CCM C;  1VQ6 C;  3CXC C;  3CCE C;  1NJI E;  1K9M E;  1YJW C;  3CPW C;  3G4S C;  2OTL C;  1YHQ C;  1Q81 E;  1K8A E;  3G71 C;  3CCU C;  1YIT C;  1QVF C;  3CCJ C;  1VQP C;  1VQ4 C;  1W2B C;  1M90 E;  3CC7 C;  3CCL C;  2QA4 C;  1YJ9 C;  1DMG A;  3G6E C;  3CD6 C;  1N8R E;  1KC8 E;  1VQK C;  4V19 F;  3CCV C;  3CC4 C;  1YJN C;  1KD1 E;  3CC2 C;  1VQN C;  2OTJ C;  1Q7Y E;  1VQ5 C;  1M1K E;  3I55 C;  1KQS C;  5DM7 C;  1VQ8 C;  3I56 C;  3CMA C;  3J7Y F;  1YIJ C;  3CME C;  3OW2 C;  1VQ9 C;  1VQO C;  1K73 E;  1VQ7 C;  1S72 C; 
#chains in the Genus database with same CATH topology
 3CCR C;  3CCS C;  1VQL C;  2QEX C;  1YI2 C;  1Q86 E;  1Q82 E;  1VQM C;  3CCQ C;  1QVG C;  1JJ2 C;  3CCM C;  1VQ6 C;  3CXC C;  3CCE C;  1NJI E;  1K9M E;  1YJW C;  3CPW C;  3G4S C;  2OTL C;  1YHQ C;  1Q81 E;  1K8A E;  3G71 C;  3CCU C;  1YIT C;  1QVF C;  3CCJ C;  1VQP C;  1VQ4 C;  1W2B C;  1M90 E;  3CC7 C;  3CCL C;  2QA4 C;  1YJ9 C;  1DMG A;  3G6E C;  3CD6 C;  1N8R E;  1KC8 E;  1VQK C;  4V19 F;  3CCV C;  3CC4 C;  1YJN C;  1KD1 E;  3CC2 C;  1VQN C;  2OTJ C;  1Q7Y E;  1VQ5 C;  1M1K E;  3I55 C;  1KQS C;  5DM7 C;  1VQ8 C;  3I56 C;  3CMA C;  3J7Y F;  1YIJ C;  3CME C;  3OW2 C;  1VQ9 C;  1VQO C;  1K73 E;  1VQ7 C;  1S72 C; 
#chains in the Genus database with same CATH homology
 3CCR C;  3CCS C;  1VQL C;  2QEX C;  1YI2 C;  1Q86 E;  1Q82 E;  1VQM C;  3CCQ C;  1QVG C;  1JJ2 C;  3CCM C;  1VQ6 C;  3CXC C;  3CCE C;  1NJI E;  1K9M E;  1YJW C;  3CPW C;  3G4S C;  2OTL C;  1YHQ C;  1Q81 E;  1K8A E;  3G71 C;  3CCU C;  1YIT C;  1QVF C;  3CCJ C;  1VQP C;  1VQ4 C;  1W2B C;  1M90 E;  3CC7 C;  3CCL C;  2QA4 C;  1YJ9 C;  1DMG A;  3G6E C;  3CD6 C;  1N8R E;  1KC8 E;  1VQK C;  4V19 F;  3CCV C;  3CC4 C;  1YJN C;  1KD1 E;  3CC2 C;  1VQN C;  2OTJ C;  1Q7Y E;  1VQ5 C;  1M1K E;  3I55 C;  1KQS C;  5DM7 C;  1VQ8 C;  3I56 C;  3CMA C;  3J7Y F;  1YIJ C;  3CME C;  3OW2 C;  1VQ9 C;  1VQO C;  1K73 E;  1VQ7 C;  1S72 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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