3CCV2

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
49
structure length
46
Chain Sequence
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDRRNHKRRHWRRNDTDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 10
structure length 46
sequence length 49
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
2 PF00832 Ribosomal_L39 Ribosomal L39 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1620.10 Mainly Alpha Orthogonal Bundle Atp Synthase Epsilon Chain; Chain: I; Ribosomal protein L39e 3ccv200
3CMA2 2QA42 3G4S2 1K8A3 3CC72 2OTJ2 3CC22 1JJ21 1Q813 1VQM2 1VQ62 1M903 1VQL2 3I562 1KC83 1VQO2 1YIJ2 1K733 1VQ42 1YJN2 3CCE2 3CCM2 1YJ92 1VQ92 1YI22 1YIT2 1KQS1 1QVF1 3CXC1 1VQN2 1N8R3 3OW21 1Q7Y3 1VQ52 1W2B1 1M1K3 3CCR2 1NJI3 3CCV2 1YJW2 3CCL2 3CCS2 3CC42 1KD13 3CCQ2 3G712 1K9M3 1VQK2 1VQP2 3CD62 3G6E2 1VQ82 2OTL2 1VQ72 1Q823 1QVG1 3CME2 1YHQ2 1Q863 3I552 1S722 3CPW1 2QEX2 3CCU2 3CCJ2
chains in the Genus database with same CATH superfamily
3CMA2 1E79I 3G4S2 2QA42 3CC72 1K8A3 2OTJ2 3CC22 1JJ21 1Q813 1VQM2 1VQ62 1M903 2WSSI 1VQL2 3I562 3ZIAI 1KC83 1VQO2 1YIJ2 4YXWI 1K733 1VQ42 2WPDI 1YJN2 3CCE2 3CCM2 1YJ92 1VQ92 1YI22 1YIT2 1KQS1 1QVF1 3CXC1 1VQN2 1N8R3 3OW21 1Q7Y3 1VQ52 1W2B1 1M1K3 3CCR2 1NJI3 3CCV2 3OFNI 3CCL2 3CCS2 1YJW2 3CC42 2XOKI 1KD13 3CCQ2 3G712 1K9M3 1VQK2 1VQP2 3CD62 2V7QI 3G6E2 1VQ82 1VQ72 1Q823 1QVG1 2OTL2 3CME2 1YHQ2 2XNDI 3I552 1S722 3CPW1 1Q863 2QEX2 3CCU2 3CCJ2
chains in the Genus database with same CATH topology
3CMA2 2QA42 3G4S2 1K8A3 3CC72 2OTJ2 3CC22 1JJ21 1Q813 1VQM2 1VQ62 1M903 1VQL2 3I562 1KC83 1VQO2 1YIJ2 1K733 1VQ42 1YJN2 3CCE2 3CCM2 1YJ92 1VQ92 1YI22 1YIT2 1KQS1 1QVF1 3CXC1 1VQN2 1N8R3 3OW21 1Q7Y3 1VQ52 1W2B1 1M1K3 3CCR2 1NJI3 3CCV2 1YJW2 3CCL2 3CCS2 3CC42 1KD13 3CCQ2 3G712 1K9M3 1VQK2 1VQP2 3CD62 3G6E2 1VQ82 2OTL2 1VQ72 1Q823 1QVG1 3CME2 1YHQ2 1Q863 3I552 1S722 3CPW1 2QEX2 3CCU2 3CCJ2
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CMA 2;  2QA4 2;  3G4S 2;  1K8A 3;  3CC7 2;  2OTJ 2;  3CC2 2;  1JJ2 1;  1Q81 3;  1VQM 2;  1VQ6 2;  1M90 3;  1VQL 2;  3I56 2;  1KC8 3;  1VQO 2;  1YIJ 2;  1K73 3;  1VQ4 2;  1YJN 2;  3CCE 2;  3CCM 2;  1YJ9 2;  1VQ9 2;  1YI2 2;  1YIT 2;  1KQS 1;  1QVF 1;  3CXC 1;  1VQN 2;  1N8R 3;  3OW2 1;  1Q7Y 3;  1VQ5 2;  1W2B 1;  1M1K 3;  3CCR 2;  1NJI 3;  3CCV 2;  1YJW 2;  3CCL 2;  3CCS 2;  3CC4 2;  1KD1 3;  3CCQ 2;  3G71 2;  1K9M 3;  1VQK 2;  1VQP 2;  3CD6 2;  3G6E 2;  1VQ8 2;  2OTL 2;  1VQ7 2;  1Q82 3;  1QVG 1;  3CME 2;  1YHQ 2;  1Q86 3;  3I55 2;  1S72 2;  3CPW 1;  2QEX 2;  3CCU 2;  3CCJ 2; 
#chains in the Genus database with same CATH topology
 3CMA 2;  1E79 I;  3G4S 2;  2QA4 2;  3CC7 2;  1K8A 3;  2OTJ 2;  3CC2 2;  1JJ2 1;  1Q81 3;  1VQM 2;  1VQ6 2;  1M90 3;  2WSS I;  1VQL 2;  3I56 2;  3ZIA I;  1KC8 3;  1VQO 2;  1YIJ 2;  4YXW I;  1K73 3;  1VQ4 2;  2WPD I;  1YJN 2;  3CCE 2;  3CCM 2;  1YJ9 2;  1VQ9 2;  1YI2 2;  1YIT 2;  1KQS 1;  1QVF 1;  3CXC 1;  1VQN 2;  1N8R 3;  3OW2 1;  1Q7Y 3;  1VQ5 2;  1W2B 1;  1M1K 3;  3CCR 2;  1NJI 3;  3CCV 2;  3OFN I;  3CCL 2;  3CCS 2;  1YJW 2;  3CC4 2;  2XOK I;  1KD1 3;  3CCQ 2;  3G71 2;  1K9M 3;  1VQK 2;  1VQP 2;  3CD6 2;  2V7Q I;  3G6E 2;  1VQ8 2;  1VQ7 2;  1Q82 3;  1QVG 1;  2OTL 2;  3CME 2;  1YHQ 2;  2XND I;  3I55 2;  1S72 2;  3CPW 1;  1Q86 3;  2QEX 2;  3CCU 2;  3CCJ 2; 
#chains in the Genus database with same CATH homology
 3CMA 2;  2QA4 2;  3G4S 2;  1K8A 3;  3CC7 2;  2OTJ 2;  3CC2 2;  1JJ2 1;  1Q81 3;  1VQM 2;  1VQ6 2;  1M90 3;  1VQL 2;  3I56 2;  1KC8 3;  1VQO 2;  1YIJ 2;  1K73 3;  1VQ4 2;  1YJN 2;  3CCE 2;  3CCM 2;  1YJ9 2;  1VQ9 2;  1YI2 2;  1YIT 2;  1KQS 1;  1QVF 1;  3CXC 1;  1VQN 2;  1N8R 3;  3OW2 1;  1Q7Y 3;  1VQ5 2;  1W2B 1;  1M1K 3;  3CCR 2;  1NJI 3;  3CCV 2;  1YJW 2;  3CCL 2;  3CCS 2;  3CC4 2;  1KD1 3;  3CCQ 2;  3G71 2;  1K9M 3;  1VQK 2;  1VQP 2;  3CD6 2;  3G6E 2;  1VQ8 2;  2OTL 2;  1VQ7 2;  1Q82 3;  1QVG 1;  3CME 2;  1YHQ 2;  1Q86 3;  3I55 2;  1S72 2;  3CPW 1;  2QEX 2;  3CCU 2;  3CCJ 2; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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