3CCVC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 61
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccvC00
3CD6C 1NJIE 1Q82E 3CC7C 1N8RE 4V19F 3CMEC 1YJNC 1QVGC 1QVFC 2OTJC 1M1KE 3G71C 1YIJC 1VQ4C 1S72C 1VQ9C 1K8AE 1VQMC 5DM7C 1JJ2C 3I55C 3I56C 3CCQC 3J7YF 1VQ7C 3CCSC 1VQ5C 3CCRC 3CCUC 1YI2C 3CCMC 3CCVC 1VQKC 3CPWC 3CCLC 1YJWC 1Q81E 1Q86E 1KC8E 1M90E 1YITC 3CCJC 2QA4C 1Q7YE 1KD1E 1YJ9C 1VQOC 1VQLC 1VQPC 3CCEC 2QEXC 3CC4C 1YHQC 3CC2C 2OTLC 1VQNC 1W2BC 3G6EC 3G4SC 3CMAC 3OW2C 1K9ME 1VQ6C 3CXCC 1DMGA 1KQSC 1VQ8C 1K73E
chains in the Genus database with same CATH superfamily
3CD6C 1NJIE 1Q82E 3CC7C 1N8RE 4V19F 3CMEC 1YJNC 1QVGC 1QVFC 2OTJC 1M1KE 3G71C 1YIJC 1VQ4C 1S72C 1VQ9C 1K8AE 1VQMC 5DM7C 1JJ2C 3I55C 3I56C 3CCQC 3J7YF 1VQ7C 3CCSC 1VQ5C 3CCRC 3CCUC 1YI2C 3CCMC 3CCVC 1VQKC 3CPWC 3CCLC 1YJWC 1Q81E 1Q86E 1KC8E 1M90E 1YITC 3CCJC 2QA4C 1Q7YE 1KD1E 1YJ9C 1VQOC 1VQLC 1VQPC 3CCEC 2QEXC 3CC4C 1YHQC 3CC2C 2OTLC 1VQNC 1W2BC 3G6EC 3G4SC 3CMAC 3OW2C 1K9ME 1VQ6C 3CXCC 1DMGA 1KQSC 1VQ8C 1K73E
chains in the Genus database with same CATH topology
3CD6C 1NJIE 1Q82E 3CC7C 1N8RE 4V19F 3CMEC 1YJNC 1QVGC 1QVFC 2OTJC 1M1KE 3G71C 1YIJC 1VQ4C 1S72C 1VQ9C 1K8AE 1VQMC 5DM7C 1JJ2C 3I55C 3I56C 3CCQC 3J7YF 1VQ7C 3CCSC 1VQ5C 3CCRC 3CCUC 1YI2C 3CCMC 3CCVC 1VQKC 3CPWC 3CCLC 1YJWC 1Q81E 1Q86E 1KC8E 1M90E 1YITC 3CCJC 2QA4C 1Q7YE 1KD1E 1YJ9C 1VQOC 1VQLC 1VQPC 3CCEC 2QEXC 3CC4C 1YHQC 3CC2C 2OTLC 1VQNC 1W2BC 3G6EC 3G4SC 3CMAC 3OW2C 1K9ME 1VQ6C 3CXCC 1DMGA 1KQSC 1VQ8C 1K73E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CD6 C;  1NJI E;  1Q82 E;  3CC7 C;  1N8R E;  4V19 F;  3CME C;  1YJN C;  1QVG C;  1QVF C;  2OTJ C;  1M1K E;  3G71 C;  1YIJ C;  1VQ4 C;  1S72 C;  1VQ9 C;  1K8A E;  1VQM C;  5DM7 C;  1JJ2 C;  3I55 C;  3I56 C;  3CCQ C;  3J7Y F;  1VQ7 C;  3CCS C;  1VQ5 C;  3CCR C;  3CCU C;  1YI2 C;  3CCM C;  3CCV C;  1VQK C;  3CPW C;  3CCL C;  1YJW C;  1Q81 E;  1Q86 E;  1KC8 E;  1M90 E;  1YIT C;  3CCJ C;  2QA4 C;  1Q7Y E;  1KD1 E;  1YJ9 C;  1VQO C;  1VQL C;  1VQP C;  3CCE C;  2QEX C;  3CC4 C;  1YHQ C;  3CC2 C;  2OTL C;  1VQN C;  1W2B C;  3G6E C;  3G4S C;  3CMA C;  3OW2 C;  1K9M E;  1VQ6 C;  3CXC C;  1DMG A;  1KQS C;  1VQ8 C;  1K73 E; 
#chains in the Genus database with same CATH topology
 3CD6 C;  1NJI E;  1Q82 E;  3CC7 C;  1N8R E;  4V19 F;  3CME C;  1YJN C;  1QVG C;  1QVF C;  2OTJ C;  1M1K E;  3G71 C;  1YIJ C;  1VQ4 C;  1S72 C;  1VQ9 C;  1K8A E;  1VQM C;  5DM7 C;  1JJ2 C;  3I55 C;  3I56 C;  3CCQ C;  3J7Y F;  1VQ7 C;  3CCS C;  1VQ5 C;  3CCR C;  3CCU C;  1YI2 C;  3CCM C;  3CCV C;  1VQK C;  3CPW C;  3CCL C;  1YJW C;  1Q81 E;  1Q86 E;  1KC8 E;  1M90 E;  1YIT C;  3CCJ C;  2QA4 C;  1Q7Y E;  1KD1 E;  1YJ9 C;  1VQO C;  1VQL C;  1VQP C;  3CCE C;  2QEX C;  3CC4 C;  1YHQ C;  3CC2 C;  2OTL C;  1VQN C;  1W2B C;  3G6E C;  3G4S C;  3CMA C;  3OW2 C;  1K9M E;  1VQ6 C;  3CXC C;  1DMG A;  1KQS C;  1VQ8 C;  1K73 E; 
#chains in the Genus database with same CATH homology
 3CD6 C;  1NJI E;  1Q82 E;  3CC7 C;  1N8R E;  4V19 F;  3CME C;  1YJN C;  1QVG C;  1QVF C;  2OTJ C;  1M1K E;  3G71 C;  1YIJ C;  1VQ4 C;  1S72 C;  1VQ9 C;  1K8A E;  1VQM C;  5DM7 C;  1JJ2 C;  3I55 C;  3I56 C;  3CCQ C;  3J7Y F;  1VQ7 C;  3CCS C;  1VQ5 C;  3CCR C;  3CCU C;  1YI2 C;  3CCM C;  3CCV C;  1VQK C;  3CPW C;  3CCL C;  1YJW C;  1Q81 E;  1Q86 E;  1KC8 E;  1M90 E;  1YIT C;  3CCJ C;  2QA4 C;  1Q7Y E;  1KD1 E;  1YJ9 C;  1VQO C;  1VQL C;  1VQP C;  3CCE C;  2QEX C;  3CC4 C;  1YHQ C;  3CC2 C;  2OTL C;  1VQN C;  1W2B C;  3G6E C;  3G4S C;  3CMA C;  3OW2 C;  1K9M E;  1VQ6 C;  3CXC C;  1DMG A;  1KQS C;  1VQ8 C;  1K73 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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