3H6DA

Structure of the mycobacterium tuberculosis dutpase d28n mutant
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
144
structure length
144
Chain Sequence
HSSGLVPRGSHMSTTLAIVRLDPGLPLPSRAHDGDAGVNLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 20
structure length 144
sequence length 144
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2009-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 3h6dA01
3HHQA 3GF0A 3ZF4A 4DHKA 1DUNA 1SLHA 3LOJA 2PC5A 3TQ4A 3MBQA 4GV8A 4WRKA 3ZF2A 2PY4A 5ECTA 2OL0A 2D4NA 2XX6A 3TRLA 1F7OA 3F4FA 3ZEZA 3TS6A 1F7PA 3TQ3A 4AO5A 1SMCA 3CA9A 2HQUA 3T6YA 4B0HA 1Q5UX 2J4HA 3HZAA 3ZF5A 1RN8A 1F7QA 1RNJA 3P48A 4APZ1 1SYLA 3ARNA 2R9QA 1PKJA 5CCTA 3ZF6A 3TP1A 2D4LA 2BT1A 1SIXA 1XS4A 2BAZA 2WE2A 2ZDCA 4XJCA 2V9XA 3EHWA 1XS1A 4AOZA 2BSYA 3T60A 1SJNA 2HXDA 3H6XA 1MQ7A 3TSLA 3ARAA 3TPSA 1DUTA 3I93A 2YZJA 2HRMA 1DUCA 2HR6A 4OOPA 1SNFA 2J4QA 1OGHA 1PKKA 1Q5HA 2WE0A 3SO2A 2WE3A 1F7DA 1EUWA 1PKHA 1EU5A 3TPYA 2WE1A 4LHRA 2OL1A 3ZF1A 1F7RA 2XCDA 3TTAA 4GK6A 3TPWA 1F7NA 2QLPA 3C3IA 2OKEA 2XY3A 2Y8CA 1F7KA 1DUDA 1VYQA 3H6DA 1SEHA 3KM3A 3TQ5A 4OOQA 4A6AA 2D4MA 1SM8A 3TRNA 4AOOA 3LQWA 1DUPA 1XS6A 3ZF3A 2XCEA 2OKBA 3ZF0A 2OKDA 3T70A 4GCYA 2Y1TA 3MDXA 5EDDA 5F9KA 3T64A 2HXBA 3ECYA 2QXXA 3C2TA 3TQZA 3TPNA 5CCOA
chains in the Genus database with same CATH superfamily
3HHQA 3GF0A 3ZF4A 4DHKA 1DUNA 1SLHA 3LOJA 2PC5A 3TQ4A 3MBQA 4GV8A 4WRKA 3ZF2A 2PY4A 5ECTA 2OL0A 2D4NA 2XX6A 3TRLA 1F7OA 3F4FA 3ZEZA 3TS6A 1F7PA 3TQ3A 4AO5A 1SMCA 3CA9A 2HQUA 3T6YA 4B0HA 1Q5UX 2J4HA 3HZAA 3ZF5A 1RN8A 1F7QA 1RNJA 3P48A 4APZ1 1SYLA 3ARNA 2R9QA 1PKJA 5CCTA 3ZF6A 3TP1A 2D4LA 2BT1A 1SIXA 1XS4A 2BAZA 2WE2A 2ZDCA 4XJCA 2V9XA 3EHWA 1XS1A 4AOZA 2BSYA 3T60A 1SJNA 2HXDA 3H6XA 1MQ7A 3TSLA 1TULA 3ARAA 3TPSA 1DUTA 3I93A 2YZJA 2HRMA 1DUCA 2HR6A 4OOPA 1SNFA 2J4QA 1OGHA 1PKKA 1Q5HA 2WE0A 3SO2A 2WE3A 1F7DA 1EUWA 1PKHA 1EU5A 3TPYA 2WE1A 4LHRA 2OL1A 3ZF1A 1F7RA 2XCDA 3TTAA 4GK6A 3TPWA 1F7NA 2QLPA 3C3IA 2OKEA 2XY3A 2Y8CA 1F7KA 1DUDA 1VYQA 3H6DA 1SEHA 3KM3A 3TQ5A 4OOQA 4A6AA 2D4MA 1SM8A 3TRNA 4AOOA 3LQWA 1DUPA 1XS6A 3ZF3A 2XCEA 2OKBA 3ZF0A 2OKDA 3T70A 4GCYA 2Y1TA 3MDXA 5EDDA 5F9KA 3T64A 2HXBA 3ECYA 2QXXA 3C2TA 3TQZA 3TPNA 5CCOA
chains in the Genus database with same CATH topology
3HHQA 3GF0A 3ZF4A 4DHKA 1DUNA 1SLHA 3LOJA 2PC5A 3TQ4A 3MBQA 4GV8A 4WRKA 3ZF2A 2PY4A 5ECTA 2OL0A 2D4NA 2XX6A 3TRLA 1F7OA 3F4FA 3ZEZA 3TS6A 1F7PA 3TQ3A 4AO5A 1SMCA 3CA9A 2HQUA 3T6YA 4B0HA 1Q5UX 2J4HA 3HZAA 3ZF5A 1RN8A 1F7QA 1RNJA 3P48A 4APZ1 1SYLA 3ARNA 2R9QA 1PKJA 5CCTA 3ZF6A 3TP1A 2D4LA 2BT1A 1SIXA 1XS4A 2BAZA 2WE2A 2ZDCA 4XJCA 2V9XA 3EHWA 1XS1A 4AOZA 2BSYA 3T60A 1SJNA 2HXDA 3H6XA 1MQ7A 3TSLA 3ARAA 3TPSA 1DUTA 3I93A 2YZJA 2HRMA 1DUCA 2HR6A 4OOPA 1SNFA 2J4QA 1OGHA 1PKKA 1Q5HA 2WE0A 3SO2A 2WE3A 1F7DA 1EUWA 1PKHA 1EU5A 3TPYA 2WE1A 4LHRA 2OL1A 3ZF1A 1F7RA 2XCDA 3TTAA 4GK6A 3TPWA 1F7NA 2QLPA 3C3IA 2OKEA 2XY3A 2Y8CA 1F7KA 1DUDA 1VYQA 3H6DA 1SEHA 3KM3A 3TQ5A 4OOQA 4A6AA 2D4MA 1SM8A 3TRNA 4AOOA 3LQWA 1DUPA 1XS6A 3ZF3A 2XCEA 2OKBA 3ZF0A 2OKDA 3T70A 4GCYA 2Y1TA 3MDXA 5EDDA 5F9KA 3T64A 2HXBA 3ECYA 2QXXA 3C2TA 3TQZA 3TPNA 5CCOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HHQ A;  3GF0 A;  3ZF4 A;  4DHK A;  1DUN A;  1SLH A;  3LOJ A;  2PC5 A;  3TQ4 A;  3MBQ A;  4GV8 A;  4WRK A;  3ZF2 A;  2PY4 A;  5ECT A;  2OL0 A;  2D4N A;  2XX6 A;  3TRL A;  1F7O A;  3F4F A;  3ZEZ A;  3TS6 A;  1F7P A;  3TQ3 A;  4AO5 A;  1SMC A;  3CA9 A;  2HQU A;  3T6Y A;  4B0H A;  1Q5U X;  2J4H A;  3HZA A;  3ZF5 A;  1RN8 A;  1F7Q A;  1RNJ A;  3P48 A;  4APZ 1;  1SYL A;  3ARN A;  2R9Q A;  1PKJ A;  5CCT A;  3ZF6 A;  3TP1 A;  2D4L A;  2BT1 A;  1SIX A;  1XS4 A;  2BAZ A;  2WE2 A;  2ZDC A;  4XJC A;  2V9X A;  3EHW A;  1XS1 A;  4AOZ A;  2BSY A;  3T60 A;  1SJN A;  2HXD A;  3H6X A;  1MQ7 A;  3TSL A;  3ARA A;  3TPS A;  1DUT A;  3I93 A;  2YZJ A;  2HRM A;  1DUC A;  2HR6 A;  4OOP A;  1SNF A;  2J4Q A;  1OGH A;  1PKK A;  1Q5H A;  2WE0 A;  3SO2 A;  2WE3 A;  1F7D A;  1EUW A;  1PKH A;  1EU5 A;  3TPY A;  2WE1 A;  4LHR A;  2OL1 A;  3ZF1 A;  1F7R A;  2XCD A;  3TTA A;  4GK6 A;  3TPW A;  1F7N A;  2QLP A;  3C3I A;  2OKE A;  2XY3 A;  2Y8C A;  1F7K A;  1DUD A;  1VYQ A;  3H6D A;  1SEH A;  3KM3 A;  3TQ5 A;  4OOQ A;  4A6A A;  2D4M A;  1SM8 A;  3TRN A;  4AOO A;  3LQW A;  1DUP A;  1XS6 A;  3ZF3 A;  2XCE A;  2OKB A;  3ZF0 A;  2OKD A;  3T70 A;  4GCY A;  2Y1T A;  3MDX A;  5EDD A;  5F9K A;  3T64 A;  2HXB A;  3ECY A;  2QXX A;  3C2T A;  3TQZ A;  3TPN A;  5CCO A; 
#chains in the Genus database with same CATH topology
 3HHQ A;  3GF0 A;  3ZF4 A;  4DHK A;  1DUN A;  1SLH A;  3LOJ A;  2PC5 A;  3TQ4 A;  3MBQ A;  4GV8 A;  4WRK A;  3ZF2 A;  2PY4 A;  5ECT A;  2OL0 A;  2D4N A;  2XX6 A;  3TRL A;  1F7O A;  3F4F A;  3ZEZ A;  3TS6 A;  1F7P A;  3TQ3 A;  4AO5 A;  1SMC A;  3CA9 A;  2HQU A;  3T6Y A;  4B0H A;  1Q5U X;  2J4H A;  3HZA A;  3ZF5 A;  1RN8 A;  1F7Q A;  1RNJ A;  3P48 A;  4APZ 1;  1SYL A;  3ARN A;  2R9Q A;  1PKJ A;  5CCT A;  3ZF6 A;  3TP1 A;  2D4L A;  2BT1 A;  1SIX A;  1XS4 A;  2BAZ A;  2WE2 A;  2ZDC A;  4XJC A;  2V9X A;  3EHW A;  1XS1 A;  4AOZ A;  2BSY A;  3T60 A;  1SJN A;  2HXD A;  3H6X A;  1MQ7 A;  3TSL A;  1TUL A;  3ARA A;  3TPS A;  1DUT A;  3I93 A;  2YZJ A;  2HRM A;  1DUC A;  2HR6 A;  4OOP A;  1SNF A;  2J4Q A;  1OGH A;  1PKK A;  1Q5H A;  2WE0 A;  3SO2 A;  2WE3 A;  1F7D A;  1EUW A;  1PKH A;  1EU5 A;  3TPY A;  2WE1 A;  4LHR A;  2OL1 A;  3ZF1 A;  1F7R A;  2XCD A;  3TTA A;  4GK6 A;  3TPW A;  1F7N A;  2QLP A;  3C3I A;  2OKE A;  2XY3 A;  2Y8C A;  1F7K A;  1DUD A;  1VYQ A;  3H6D A;  1SEH A;  3KM3 A;  3TQ5 A;  4OOQ A;  4A6A A;  2D4M A;  1SM8 A;  3TRN A;  4AOO A;  3LQW A;  1DUP A;  1XS6 A;  3ZF3 A;  2XCE A;  2OKB A;  3ZF0 A;  2OKD A;  3T70 A;  4GCY A;  2Y1T A;  3MDX A;  5EDD A;  5F9K A;  3T64 A;  2HXB A;  3ECY A;  2QXX A;  3C2T A;  3TQZ A;  3TPN A;  5CCO A; 
#chains in the Genus database with same CATH homology
 3HHQ A;  3GF0 A;  3ZF4 A;  4DHK A;  1DUN A;  1SLH A;  3LOJ A;  2PC5 A;  3TQ4 A;  3MBQ A;  4GV8 A;  4WRK A;  3ZF2 A;  2PY4 A;  5ECT A;  2OL0 A;  2D4N A;  2XX6 A;  3TRL A;  1F7O A;  3F4F A;  3ZEZ A;  3TS6 A;  1F7P A;  3TQ3 A;  4AO5 A;  1SMC A;  3CA9 A;  2HQU A;  3T6Y A;  4B0H A;  1Q5U X;  2J4H A;  3HZA A;  3ZF5 A;  1RN8 A;  1F7Q A;  1RNJ A;  3P48 A;  4APZ 1;  1SYL A;  3ARN A;  2R9Q A;  1PKJ A;  5CCT A;  3ZF6 A;  3TP1 A;  2D4L A;  2BT1 A;  1SIX A;  1XS4 A;  2BAZ A;  2WE2 A;  2ZDC A;  4XJC A;  2V9X A;  3EHW A;  1XS1 A;  4AOZ A;  2BSY A;  3T60 A;  1SJN A;  2HXD A;  3H6X A;  1MQ7 A;  3TSL A;  3ARA A;  3TPS A;  1DUT A;  3I93 A;  2YZJ A;  2HRM A;  1DUC A;  2HR6 A;  4OOP A;  1SNF A;  2J4Q A;  1OGH A;  1PKK A;  1Q5H A;  2WE0 A;  3SO2 A;  2WE3 A;  1F7D A;  1EUW A;  1PKH A;  1EU5 A;  3TPY A;  2WE1 A;  4LHR A;  2OL1 A;  3ZF1 A;  1F7R A;  2XCD A;  3TTA A;  4GK6 A;  3TPW A;  1F7N A;  2QLP A;  3C3I A;  2OKE A;  2XY3 A;  2Y8C A;  1F7K A;  1DUD A;  1VYQ A;  3H6D A;  1SEH A;  3KM3 A;  3TQ5 A;  4OOQ A;  4A6A A;  2D4M A;  1SM8 A;  3TRN A;  4AOO A;  3LQW A;  1DUP A;  1XS6 A;  3ZF3 A;  2XCE A;  2OKB A;  3ZF0 A;  2OKD A;  3T70 A;  4GCY A;  2Y1T A;  3MDX A;  5EDD A;  5F9K A;  3T64 A;  2HXB A;  3ECY A;  2QXX A;  3C2T A;  3TQZ A;  3TPN A;  5CCO A; 
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similar chains in the Genus database (?% sequence similarity)
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