3I93A

Crystal structure of mycobacterium tuberculosis dutpase stop138t mutant
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
144
structure length
140
Chain Sequence
SSGLVPRSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 21
structure length 140
sequence length 144
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2009-07-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 3i93A01
3TQ4A 3TSLA 1OGHA 2QXXA 3TS6A 5EDDA 3P48A 3SO2A 2OKDA 1PKHA 1RN8A 1F7QA 3C3IA 2Y1TA 3KM3A 3TPNA 1MQ7A 3HHQA 2J4HA 2BT1A 3EHWA 3ECYA 3ZF1A 3T64A 1F7DA 1RNJA 1F7KA 2D4MA 3TTAA 3ZF5A 1EUWA 1DUDA 4DHKA 2PC5A 2OL0A 3ARAA 1SYLA 4GV8A 1SM8A 2QLPA 3LOJA 3T60A 3ZF6A 5CCOA 2WE3A 1F7RA 4GK6A 3ZF2A 4APZ1 4AOOA 3TQ3A 3ZEZA 5ECTA 3C2TA 2XCEA 1XS1A 1Q5UX 3TPSA 2BSYA 1SIXA 3TRNA 4OOPA 1F7PA 3GF0A 3MDXA 3F4FA 3H6DA 3TP1A 1SJNA 4B0HA 2V9XA 1XS4A 1XS6A 3CA9A 4OOQA 4WRKA 5CCTA 2R9QA 2XCDA 4GCYA 5F9KA 2D4NA 4XJCA 3HZAA 4LHRA 3TQ5A 3MBQA 1SLHA 3ZF4A 1VYQA 2BAZA 2PY4A 3ARNA 1SEHA 1EU5A 2J4QA 2WE0A 3TPWA 2XX6A 3ZF3A 2HRMA 1DUNA 2Y8CA 3H6XA 3T70A 1PKKA 2ZDCA 1SMCA 1DUCA 1PKJA 3TQZA 1SNFA 4AOZA 2OKEA 2WE2A 3T6YA 3I93A 2YZJA 2OL1A 4AO5A 2D4LA 3TRLA 1DUPA 3ZF0A 2HR6A 1Q5HA 1DUTA 2XY3A 2WE1A 3LQWA 4A6AA 1F7NA 2OKBA 1F7OA 2HXDA 3TPYA 2HXBA 2HQUA
chains in the Genus database with same CATH superfamily
3TQ4A 3TSLA 1OGHA 2QXXA 3TS6A 5EDDA 3P48A 3SO2A 2OKDA 1PKHA 1RN8A 1F7QA 3C3IA 2Y1TA 3KM3A 3TPNA 1MQ7A 3HHQA 2J4HA 2BT1A 3EHWA 3ECYA 3ZF1A 3T64A 1F7DA 1RNJA 1F7KA 2D4MA 3TTAA 3ZF5A 1EUWA 1DUDA 4DHKA 2PC5A 2OL0A 3ARAA 1SYLA 4GV8A 1SM8A 2QLPA 3LOJA 3T60A 3ZF6A 5CCOA 2WE3A 1F7RA 4GK6A 3ZF2A 4APZ1 4AOOA 3TQ3A 3ZEZA 5ECTA 3C2TA 1TULA 2XCEA 1XS1A 1Q5UX 3TPSA 2BSYA 1SIXA 3TRNA 4OOPA 1F7PA 3GF0A 3MDXA 3F4FA 3H6DA 3TP1A 1SJNA 4B0HA 2V9XA 1XS4A 1XS6A 3CA9A 4OOQA 4WRKA 5CCTA 2R9QA 2XCDA 4GCYA 5F9KA 2D4NA 4XJCA 3HZAA 4LHRA 3TQ5A 3MBQA 1SLHA 3ZF4A 1VYQA 2BAZA 2PY4A 3ARNA 1SEHA 1EU5A 2J4QA 2WE0A 3TPWA 2XX6A 3ZF3A 2HRMA 1DUNA 2Y8CA 3H6XA 3T70A 1PKKA 2ZDCA 1SMCA 1DUCA 1PKJA 3TQZA 1SNFA 4AOZA 2OKEA 2WE2A 3T6YA 3I93A 2YZJA 2OL1A 4AO5A 2D4LA 3TRLA 1DUPA 3ZF0A 2HR6A 1Q5HA 1DUTA 2XY3A 2WE1A 3LQWA 4A6AA 1F7NA 2OKBA 1F7OA 2HXDA 3TPYA 2HXBA 2HQUA
chains in the Genus database with same CATH topology
3TQ4A 3TSLA 1OGHA 2QXXA 3TS6A 5EDDA 3P48A 3SO2A 2OKDA 1PKHA 1RN8A 1F7QA 3C3IA 2Y1TA 3KM3A 3TPNA 1MQ7A 3HHQA 2J4HA 2BT1A 3EHWA 3ECYA 3ZF1A 3T64A 1F7DA 1RNJA 1F7KA 2D4MA 3TTAA 3ZF5A 1EUWA 1DUDA 4DHKA 2PC5A 2OL0A 3ARAA 1SYLA 4GV8A 1SM8A 2QLPA 3LOJA 3T60A 3ZF6A 5CCOA 2WE3A 1F7RA 4GK6A 3ZF2A 4APZ1 4AOOA 3TQ3A 3ZEZA 5ECTA 3C2TA 2XCEA 1XS1A 1Q5UX 3TPSA 2BSYA 1SIXA 3TRNA 4OOPA 1F7PA 3GF0A 3MDXA 3F4FA 3H6DA 3TP1A 1SJNA 4B0HA 2V9XA 1XS4A 1XS6A 3CA9A 4OOQA 4WRKA 5CCTA 2R9QA 2XCDA 4GCYA 5F9KA 2D4NA 4XJCA 3HZAA 4LHRA 3TQ5A 3MBQA 1SLHA 3ZF4A 1VYQA 2BAZA 2PY4A 3ARNA 1SEHA 1EU5A 2J4QA 2WE0A 3TPWA 2XX6A 3ZF3A 2HRMA 1DUNA 2Y8CA 3H6XA 3T70A 1PKKA 2ZDCA 1SMCA 1DUCA 1PKJA 3TQZA 1SNFA 4AOZA 2OKEA 2WE2A 3T6YA 3I93A 2YZJA 2OL1A 4AO5A 2D4LA 3TRLA 1DUPA 3ZF0A 2HR6A 1Q5HA 1DUTA 2XY3A 2WE1A 3LQWA 4A6AA 1F7NA 2OKBA 1F7OA 2HXDA 3TPYA 2HXBA 2HQUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TQ4 A;  3TSL A;  1OGH A;  2QXX A;  3TS6 A;  5EDD A;  3P48 A;  3SO2 A;  2OKD A;  1PKH A;  1RN8 A;  1F7Q A;  3C3I A;  2Y1T A;  3KM3 A;  3TPN A;  1MQ7 A;  3HHQ A;  2J4H A;  2BT1 A;  3EHW A;  3ECY A;  3ZF1 A;  3T64 A;  1F7D A;  1RNJ A;  1F7K A;  2D4M A;  3TTA A;  3ZF5 A;  1EUW A;  1DUD A;  4DHK A;  2PC5 A;  2OL0 A;  3ARA A;  1SYL A;  4GV8 A;  1SM8 A;  2QLP A;  3LOJ A;  3T60 A;  3ZF6 A;  5CCO A;  2WE3 A;  1F7R A;  4GK6 A;  3ZF2 A;  4APZ 1;  4AOO A;  3TQ3 A;  3ZEZ A;  5ECT A;  3C2T A;  2XCE A;  1XS1 A;  1Q5U X;  3TPS A;  2BSY A;  1SIX A;  3TRN A;  4OOP A;  1F7P A;  3GF0 A;  3MDX A;  3F4F A;  3H6D A;  3TP1 A;  1SJN A;  4B0H A;  2V9X A;  1XS4 A;  1XS6 A;  3CA9 A;  4OOQ A;  4WRK A;  5CCT A;  2R9Q A;  2XCD A;  4GCY A;  5F9K A;  2D4N A;  4XJC A;  3HZA A;  4LHR A;  3TQ5 A;  3MBQ A;  1SLH A;  3ZF4 A;  1VYQ A;  2BAZ A;  2PY4 A;  3ARN A;  1SEH A;  1EU5 A;  2J4Q A;  2WE0 A;  3TPW A;  2XX6 A;  3ZF3 A;  2HRM A;  1DUN A;  2Y8C A;  3H6X A;  3T70 A;  1PKK A;  2ZDC A;  1SMC A;  1DUC A;  1PKJ A;  3TQZ A;  1SNF A;  4AOZ A;  2OKE A;  2WE2 A;  3T6Y A;  3I93 A;  2YZJ A;  2OL1 A;  4AO5 A;  2D4L A;  3TRL A;  1DUP A;  3ZF0 A;  2HR6 A;  1Q5H A;  1DUT A;  2XY3 A;  2WE1 A;  3LQW A;  4A6A A;  1F7N A;  2OKB A;  1F7O A;  2HXD A;  3TPY A;  2HXB A;  2HQU A; 
#chains in the Genus database with same CATH topology
 3TQ4 A;  3TSL A;  1OGH A;  2QXX A;  3TS6 A;  5EDD A;  3P48 A;  3SO2 A;  2OKD A;  1PKH A;  1RN8 A;  1F7Q A;  3C3I A;  2Y1T A;  3KM3 A;  3TPN A;  1MQ7 A;  3HHQ A;  2J4H A;  2BT1 A;  3EHW A;  3ECY A;  3ZF1 A;  3T64 A;  1F7D A;  1RNJ A;  1F7K A;  2D4M A;  3TTA A;  3ZF5 A;  1EUW A;  1DUD A;  4DHK A;  2PC5 A;  2OL0 A;  3ARA A;  1SYL A;  4GV8 A;  1SM8 A;  2QLP A;  3LOJ A;  3T60 A;  3ZF6 A;  5CCO A;  2WE3 A;  1F7R A;  4GK6 A;  3ZF2 A;  4APZ 1;  4AOO A;  3TQ3 A;  3ZEZ A;  5ECT A;  3C2T A;  1TUL A;  2XCE A;  1XS1 A;  1Q5U X;  3TPS A;  2BSY A;  1SIX A;  3TRN A;  4OOP A;  1F7P A;  3GF0 A;  3MDX A;  3F4F A;  3H6D A;  3TP1 A;  1SJN A;  4B0H A;  2V9X A;  1XS4 A;  1XS6 A;  3CA9 A;  4OOQ A;  4WRK A;  5CCT A;  2R9Q A;  2XCD A;  4GCY A;  5F9K A;  2D4N A;  4XJC A;  3HZA A;  4LHR A;  3TQ5 A;  3MBQ A;  1SLH A;  3ZF4 A;  1VYQ A;  2BAZ A;  2PY4 A;  3ARN A;  1SEH A;  1EU5 A;  2J4Q A;  2WE0 A;  3TPW A;  2XX6 A;  3ZF3 A;  2HRM A;  1DUN A;  2Y8C A;  3H6X A;  3T70 A;  1PKK A;  2ZDC A;  1SMC A;  1DUC A;  1PKJ A;  3TQZ A;  1SNF A;  4AOZ A;  2OKE A;  2WE2 A;  3T6Y A;  3I93 A;  2YZJ A;  2OL1 A;  4AO5 A;  2D4L A;  3TRL A;  1DUP A;  3ZF0 A;  2HR6 A;  1Q5H A;  1DUT A;  2XY3 A;  2WE1 A;  3LQW A;  4A6A A;  1F7N A;  2OKB A;  1F7O A;  2HXD A;  3TPY A;  2HXB A;  2HQU A; 
#chains in the Genus database with same CATH homology
 3TQ4 A;  3TSL A;  1OGH A;  2QXX A;  3TS6 A;  5EDD A;  3P48 A;  3SO2 A;  2OKD A;  1PKH A;  1RN8 A;  1F7Q A;  3C3I A;  2Y1T A;  3KM3 A;  3TPN A;  1MQ7 A;  3HHQ A;  2J4H A;  2BT1 A;  3EHW A;  3ECY A;  3ZF1 A;  3T64 A;  1F7D A;  1RNJ A;  1F7K A;  2D4M A;  3TTA A;  3ZF5 A;  1EUW A;  1DUD A;  4DHK A;  2PC5 A;  2OL0 A;  3ARA A;  1SYL A;  4GV8 A;  1SM8 A;  2QLP A;  3LOJ A;  3T60 A;  3ZF6 A;  5CCO A;  2WE3 A;  1F7R A;  4GK6 A;  3ZF2 A;  4APZ 1;  4AOO A;  3TQ3 A;  3ZEZ A;  5ECT A;  3C2T A;  2XCE A;  1XS1 A;  1Q5U X;  3TPS A;  2BSY A;  1SIX A;  3TRN A;  4OOP A;  1F7P A;  3GF0 A;  3MDX A;  3F4F A;  3H6D A;  3TP1 A;  1SJN A;  4B0H A;  2V9X A;  1XS4 A;  1XS6 A;  3CA9 A;  4OOQ A;  4WRK A;  5CCT A;  2R9Q A;  2XCD A;  4GCY A;  5F9K A;  2D4N A;  4XJC A;  3HZA A;  4LHR A;  3TQ5 A;  3MBQ A;  1SLH A;  3ZF4 A;  1VYQ A;  2BAZ A;  2PY4 A;  3ARN A;  1SEH A;  1EU5 A;  2J4Q A;  2WE0 A;  3TPW A;  2XX6 A;  3ZF3 A;  2HRM A;  1DUN A;  2Y8C A;  3H6X A;  3T70 A;  1PKK A;  2ZDC A;  1SMC A;  1DUC A;  1PKJ A;  3TQZ A;  1SNF A;  4AOZ A;  2OKE A;  2WE2 A;  3T6Y A;  3I93 A;  2YZJ A;  2OL1 A;  4AO5 A;  2D4L A;  3TRL A;  1DUP A;  3ZF0 A;  2HR6 A;  1Q5H A;  1DUT A;  2XY3 A;  2WE1 A;  3LQW A;  4A6A A;  1F7N A;  2OKB A;  1F7O A;  2HXD A;  3TPY A;  2HXB A;  2HQU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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