3IG6C

Low molecular weigth human urokinase type plasminogen activator 2-[6-(3'-aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complex
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
9
structure length
9
Chain Sequence
KFQCGQKTL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Identification of orally bioavailable, non-amidine inhibitors of Urokinase Plasminogen Activator (uPA)
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Urokinase-type plasminogen activator
structure length 9
sequence length 9
chains with identical sequence A
ec nomenclature ec 3.4.21.73: U-plasminogen activator.
pdb deposition date 2009-07-27
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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