3RJQA

Crystal structure of anti-hiv llama vhh antibody a12 in complex with c186 gp120
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
356
structure length
292
Chain Sequence
WKEAKTTLFCASDAKAYEKEVHNVWATHACVPTDPNPQEMVLANVTENFNMWKNDMVEQMHEDIISLWDESLKVSFDPIPLHYCAPAGFAILKCNNKTFNGTGPCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNESVNIVCTRAHCNINESKWNNTLQKVGEELAKHFPSKTIKFEPSSGGDLEITTHSFNCRGEFFYCNTSDLFNGTYRNGTYNHTGTITLQCKIKQTCNSNITGLLLLRDGDTETFRPGGGDMRDNWRSELYKYKVVEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus type 1
molecule keywords C186 gp120
total genus 64
structure length 292
sequence length 356
ec nomenclature
pdb deposition date 2011-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 3rjqA00
4YDKG 4OLYG 4DKVA 4JM2E 2NY1A 4LSSG 4XVSG 4DVXA 2NXZA 4LSTG 4JDTG 4OLVG 5F4LA 4XNZA 4JZZA 4DVTA 2NY6A 4LAJA 2NY0A 2I60G 4JB9G 4YDJG 3IDYA 4XMPG 2NY4A 4I54A 4JPVG 5TE4G 3TGSA 3FUSA 4DKUA 4OLWG 2NY7G 5TE7G 5CD5A 2NY5G 1YYLG 4OLXG 5F96G 4YE4G 4LSPG 3JWDA 4DKQA 2I5YG 2BF1A 4DVSA 4OLUG 3TGTA 4RWYA 1GC1G 5T33G 3SE8G 4LSQG 4XNYG 1YYMG 4JKPG 4S1RG 5FECC 3TGQA 3JWOA 4JPWG 5F9OG 4JZWA 4R4NA 2QADA 5I9QA 4RX4E 3LQAG 4YFLE 4DKRA 5F9WA 4DVVA 4OM0G 4XVTG 1G9MG 1RZJG 4OLZG 4S1QG 4LSVG 2NY3A 5F4PA 4LSRG 3HI1G 4K0AA 2NY2A 5CAYG 2NXYA 4RFNA 4J6RG 4YDLA 4RFOG 4I53A 5F4RA 4LSUG 4RZ8A 3NGBA 5TE6G 3TIHA 4DKOA 4P9HG 3IDXG 4R2GA 5F4UA 3U7YG 4S1SG 4OM1G 4DVWA 4YDIG 2B4CG 3SE9G 4DVRG 4H8WG 3TGRA 4KA2A 1RZKG 1G9NG 4DKPA 5KJRG 4R4FA 3RJQA 5FA2A 5IGXG
chains in the Genus database with same CATH superfamily
4YDKG 4OLYG 4DKVA 4JM2E 2NY1A 4LSSG 4XVSG 4DVXA 2NXZA 4LSTG 4JDTG 4OLVG 5F4LA 4XNZA 4JZZA 4DVTA 2NY6A 4LAJA 2NY0A 2I60G 4JB9G 4YDJG 3IDYA 4XMPG 2NY4A 4I54A 4JPVG 5TE4G 3TGSA 3FUSA 4DKUA 4OLWG 2NY7G 5TE7G 5CD5A 2NY5G 1YYLG 4OLXG 5F96G 4YE4G 4LSPG 3JWDA 4DKQA 2I5YG 2BF1A 4DVSA 4OLUG 3TGTA 4RWYA 1GC1G 5T33G 3SE8G 4LSQG 4XNYG 1YYMG 4JKPG 4S1RG 5FECC 3TGQA 3JWOA 4JPWG 5F9OG 4JZWA 4R4NA 2QADA 5I9QA 4RX4E 3LQAG 4YFLE 4DKRA 5F9WA 4DVVA 4OM0G 4XVTG 1G9MG 1RZJG 4OLZG 4S1QG 4LSVG 2NY3A 5F4PA 4LSRG 3HI1G 4K0AA 2NY2A 5CAYG 2NXYA 4RFNA 4J6RG 4YDLA 4RFOG 4I53A 5F4RA 4LSUG 4RZ8A 3NGBA 5TE6G 3TIHA 4DKOA 4P9HG 3IDXG 4R2GA 5F4UA 3U7YG 4S1SG 4OM1G 4DVWA 4YDIG 2B4CG 3SE9G 4DVRG 4H8WG 3TGRA 4KA2A 1RZKG 1G9NG 4DKPA 5KJRG 4R4FA 3RJQA 5FA2A 5IGXG
chains in the Genus database with same CATH topology
4YDKG 4OLYG 4DKVA 4JM2E 2NY1A 4LSSG 4XVSG 4DVXA 2NXZA 4LSTG 4JDTG 4OLVG 5F4LA 4XNZA 4JZZA 4DVTA 2NY6A 4LAJA 2NY0A 2I60G 4JB9G 4YDJG 3IDYA 4XMPG 2NY4A 4I54A 4JPVG 5TE4G 3TGSA 3FUSA 4DKUA 4OLWG 2NY7G 5TE7G 5CD5A 2NY5G 1YYLG 4OLXG 5F96G 4YE4G 4LSPG 3JWDA 4DKQA 2I5YG 2BF1A 4DVSA 4OLUG 3TGTA 4RWYA 1GC1G 5T33G 3SE8G 4LSQG 4XNYG 1YYMG 4JKPG 4S1RG 5FECC 3TGQA 3JWOA 4JPWG 5F9OG 4JZWA 4R4NA 2QADA 5I9QA 4RX4E 3LQAG 4YFLE 4DKRA 5F9WA 4DVVA 4OM0G 4XVTG 1G9MG 1RZJG 4OLZG 4S1QG 4LSVG 2NY3A 5F4PA 4LSRG 3HI1G 4K0AA 2NY2A 5CAYG 2NXYA 4RFNA 4J6RG 4YDLA 4RFOG 4I53A 5F4RA 4LSUG 4RZ8A 3NGBA 5TE6G 3TIHA 4DKOA 4P9HG 3IDXG 4R2GA 5F4UA 3U7YG 4S1SG 4OM1G 4DVWA 4YDIG 2B4CG 3SE9G 4DVRG 4H8WG 3TGRA 4KA2A 1RZKG 1G9NG 4DKPA 5KJRG 4R4FA 3RJQA 5FA2A 5IGXG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YDK G;  4OLY G;  4DKV A;  4JM2 E;  2NY1 A;  4LSS G;  4XVS G;  4DVX A;  2NXZ A;  4LST G;  4JDT G;  4OLV G;  5F4L A;  4XNZ A;  4JZZ A;  4DVT A;  2NY6 A;  4LAJ A;  2NY0 A;  2I60 G;  4JB9 G;  4YDJ G;  3IDY A;  4XMP G;  2NY4 A;  4I54 A;  4JPV G;  5TE4 G;  3TGS A;  3FUS A;  4DKU A;  4OLW G;  2NY7 G;  5TE7 G;  5CD5 A;  2NY5 G;  1YYL G;  4OLX G;  5F96 G;  4YE4 G;  4LSP G;  3JWD A;  4DKQ A;  2I5Y G;  2BF1 A;  4DVS A;  4OLU G;  3TGT A;  4RWY A;  1GC1 G;  5T33 G;  3SE8 G;  4LSQ G;  4XNY G;  1YYM G;  4JKP G;  4S1R G;  5FEC C;  3TGQ A;  3JWO A;  4JPW G;  5F9O G;  4JZW A;  4R4N A;  2QAD A;  5I9Q A;  4RX4 E;  3LQA G;  4YFL E;  4DKR A;  5F9W A;  4DVV A;  4OM0 G;  4XVT G;  1G9M G;  1RZJ G;  4OLZ G;  4S1Q G;  4LSV G;  2NY3 A;  5F4P A;  4LSR G;  3HI1 G;  4K0A A;  2NY2 A;  5CAY G;  2NXY A;  4RFN A;  4J6R G;  4YDL A;  4RFO G;  4I53 A;  5F4R A;  4LSU G;  4RZ8 A;  3NGB A;  5TE6 G;  3TIH A;  4DKO A;  4P9H G;  3IDX G;  4R2G A;  5F4U A;  3U7Y G;  4S1S G;  4OM1 G;  4DVW A;  4YDI G;  2B4C G;  3SE9 G;  4DVR G;  4H8W G;  3TGR A;  4KA2 A;  1RZK G;  1G9N G;  4DKP A;  5KJR G;  4R4F A;  3RJQ A;  5FA2 A;  5IGX G; 
#chains in the Genus database with same CATH topology
 4YDK G;  4OLY G;  4DKV A;  4JM2 E;  2NY1 A;  4LSS G;  4XVS G;  4DVX A;  2NXZ A;  4LST G;  4JDT G;  4OLV G;  5F4L A;  4XNZ A;  4JZZ A;  4DVT A;  2NY6 A;  4LAJ A;  2NY0 A;  2I60 G;  4JB9 G;  4YDJ G;  3IDY A;  4XMP G;  2NY4 A;  4I54 A;  4JPV G;  5TE4 G;  3TGS A;  3FUS A;  4DKU A;  4OLW G;  2NY7 G;  5TE7 G;  5CD5 A;  2NY5 G;  1YYL G;  4OLX G;  5F96 G;  4YE4 G;  4LSP G;  3JWD A;  4DKQ A;  2I5Y G;  2BF1 A;  4DVS A;  4OLU G;  3TGT A;  4RWY A;  1GC1 G;  5T33 G;  3SE8 G;  4LSQ G;  4XNY G;  1YYM G;  4JKP G;  4S1R G;  5FEC C;  3TGQ A;  3JWO A;  4JPW G;  5F9O G;  4JZW A;  4R4N A;  2QAD A;  5I9Q A;  4RX4 E;  3LQA G;  4YFL E;  4DKR A;  5F9W A;  4DVV A;  4OM0 G;  4XVT G;  1G9M G;  1RZJ G;  4OLZ G;  4S1Q G;  4LSV G;  2NY3 A;  5F4P A;  4LSR G;  3HI1 G;  4K0A A;  2NY2 A;  5CAY G;  2NXY A;  4RFN A;  4J6R G;  4YDL A;  4RFO G;  4I53 A;  5F4R A;  4LSU G;  4RZ8 A;  3NGB A;  5TE6 G;  3TIH A;  4DKO A;  4P9H G;  3IDX G;  4R2G A;  5F4U A;  3U7Y G;  4S1S G;  4OM1 G;  4DVW A;  4YDI G;  2B4C G;  3SE9 G;  4DVR G;  4H8W G;  3TGR A;  4KA2 A;  1RZK G;  1G9N G;  4DKP A;  5KJR G;  4R4F A;  3RJQ A;  5FA2 A;  5IGX G; 
#chains in the Genus database with same CATH homology
 4YDK G;  4OLY G;  4DKV A;  4JM2 E;  2NY1 A;  4LSS G;  4XVS G;  4DVX A;  2NXZ A;  4LST G;  4JDT G;  4OLV G;  5F4L A;  4XNZ A;  4JZZ A;  4DVT A;  2NY6 A;  4LAJ A;  2NY0 A;  2I60 G;  4JB9 G;  4YDJ G;  3IDY A;  4XMP G;  2NY4 A;  4I54 A;  4JPV G;  5TE4 G;  3TGS A;  3FUS A;  4DKU A;  4OLW G;  2NY7 G;  5TE7 G;  5CD5 A;  2NY5 G;  1YYL G;  4OLX G;  5F96 G;  4YE4 G;  4LSP G;  3JWD A;  4DKQ A;  2I5Y G;  2BF1 A;  4DVS A;  4OLU G;  3TGT A;  4RWY A;  1GC1 G;  5T33 G;  3SE8 G;  4LSQ G;  4XNY G;  1YYM G;  4JKP G;  4S1R G;  5FEC C;  3TGQ A;  3JWO A;  4JPW G;  5F9O G;  4JZW A;  4R4N A;  2QAD A;  5I9Q A;  4RX4 E;  3LQA G;  4YFL E;  4DKR A;  5F9W A;  4DVV A;  4OM0 G;  4XVT G;  1G9M G;  1RZJ G;  4OLZ G;  4S1Q G;  4LSV G;  2NY3 A;  5F4P A;  4LSR G;  3HI1 G;  4K0A A;  2NY2 A;  5CAY G;  2NXY A;  4RFN A;  4J6R G;  4YDL A;  4RFO G;  4I53 A;  5F4R A;  4LSU G;  4RZ8 A;  3NGB A;  5TE6 G;  3TIH A;  4DKO A;  4P9H G;  3IDX G;  4R2G A;  5F4U A;  3U7Y G;  4S1S G;  4OM1 G;  4DVW A;  4YDI G;  2B4C G;  3SE9 G;  4DVR G;  4H8W G;  3TGR A;  4KA2 A;  1RZK G;  1G9N G;  4DKP A;  5KJR G;  4R4F A;  3RJQ A;  5FA2 A;  5IGX G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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