3TIHA

Crystal structure of unliganded hiv-1 clade c strain zm109f.pb4 gp120 core
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
345
structure length
326
Chain Sequence
VWKEAKTTLFCASDAKSYEREVHNVWATHACVPTDPDPQELVMANVTENFNMWKNDMVDQMHEDIISLWDQSLKPCVKLTGGSTITQACPKVSFDPIPIHYCAPAGYAILKCNNKTFSGKGPCSNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENLTDNAKTIIVHLNKSVEIECIRPGNGDIRKAYCKINGSEWNETLTKVSEKLKKTIRFAQHSGGDLEVTTHSFNCRGEFFYCNTSELFNSSNITLPCRIKQIINMWQGVGRAMYAPPIRGEIKCTSNITGILLTRDGSTEEIFRPEGGNMRDNWRSELYKYKVVEIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 clade C ZM109F.PB4 gp120
total genus 59
structure length 326
sequence length 345
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-08-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 3tihA01
3TGTA 3HI1G 4DVRG 1RZJG 4RWYA 5CAYG 4DVSA 5F4RA 3JWOA 4XVTG 4I53A 5TE7G 4JM2E 2B4CG 4YE4G 1RZKG 4YDLA 4RFOG 4LSVG 2I5YG 3TGSA 3TIHA 4DKVA 4OLZG 4P9HG 5F4UA 4YFLE 3TGRA 2NXZA 4XNYG 2NY7G 4I54A 5KJRG 4LSPG 4S1RG 3FUSA 4JPWG 2BF1A 2NY5G 4RZ8A 5IGXG 4OLWG 2I60G 3U7YG 2NY0A 4LSTG 2QADA 5F9OG 5CD5A 4OLUG 4KA2A 4JPVG 1GC1G 4XMPG 4LAJA 4YDJG 2NXYA 4DKPA 3IDXG 4OLVG 4JDTG 4DVWA 3SE9G 4JB9G 5TE4G 4YDIG 5FECC 4DVXA 4XNZA 4LSUG 2NY4A 4R4NA 4DKOA 5F9WA 4DKRA 4R2GA 4RX4E 3SE8G 4LSQG 5FA2A 3IDYA 3NGBA 5F96G 2NY3A 4DVTA 5I9QA 4S1SG 4DVVA 4R4FA 5F4LA 4OLXG 2NY1A 4H8WG 4OM0G 3RJQA 1G9MG 4OLYG 4JKPG 4DKUA 5TE6G 4OM1G 5F4PA 4S1QG 3TGQA 4RFNA 5T33G 3JWDA 4DKQA 4XVSG 4LSRG 3LQAG 4J6RG 4JZWA 4K0AA 1YYLG 1YYMG 1G9NG 2NY2A 4LSSG 4JZZA 4YDKG 2NY6A
chains in the Genus database with same CATH superfamily
3TGTA 3HI1G 4DVRG 1RZJG 4RWYA 5CAYG 4DVSA 5F4RA 3JWOA 4XVTG 4I53A 5TE7G 4JM2E 2B4CG 4YE4G 1RZKG 4YDLA 4RFOG 4LSVG 2I5YG 3TGSA 3TIHA 4DKVA 4OLZG 4P9HG 5F4UA 4YFLE 3TGRA 2NXZA 4XNYG 2NY7G 4I54A 5KJRG 4LSPG 4S1RG 3FUSA 4JPWG 2BF1A 2NY5G 4RZ8A 5IGXG 4OLWG 2I60G 3U7YG 2NY0A 4LSTG 2QADA 5F9OG 5CD5A 4OLUG 4KA2A 4JPVG 1GC1G 4XMPG 4LAJA 4YDJG 2NXYA 4DKPA 3IDXG 4OLVG 4JDTG 4DVWA 3SE9G 4JB9G 5TE4G 4YDIG 5FECC 4DVXA 4XNZA 4LSUG 2NY4A 4R4NA 4DKOA 5F9WA 4DKRA 4R2GA 4RX4E 3SE8G 4LSQG 5FA2A 3IDYA 3NGBA 5F96G 2NY3A 4DVTA 5I9QA 4S1SG 4DVVA 4R4FA 5F4LA 4OLXG 2NY1A 4H8WG 4OM0G 3RJQA 1G9MG 4OLYG 4JKPG 4DKUA 5TE6G 4OM1G 5F4PA 4S1QG 3TGQA 4RFNA 5T33G 3JWDA 4DKQA 4XVSG 4LSRG 3LQAG 4J6RG 4JZWA 4K0AA 1YYLG 1YYMG 1G9NG 2NY2A 4LSSG 4JZZA 4YDKG 2NY6A
chains in the Genus database with same CATH topology
3TGTA 3HI1G 4DVRG 1RZJG 4RWYA 5CAYG 4DVSA 5F4RA 3JWOA 4XVTG 4I53A 5TE7G 4JM2E 2B4CG 4YE4G 1RZKG 4YDLA 4RFOG 4LSVG 2I5YG 3TGSA 3TIHA 4DKVA 4OLZG 4P9HG 5F4UA 4YFLE 3TGRA 2NXZA 4XNYG 2NY7G 4I54A 5KJRG 4LSPG 4S1RG 3FUSA 4JPWG 2BF1A 2NY5G 4RZ8A 5IGXG 4OLWG 2I60G 3U7YG 2NY0A 4LSTG 2QADA 5F9OG 5CD5A 4OLUG 4KA2A 4JPVG 1GC1G 4XMPG 4LAJA 4YDJG 2NXYA 4DKPA 3IDXG 4OLVG 4JDTG 4DVWA 3SE9G 4JB9G 5TE4G 4YDIG 5FECC 4DVXA 4XNZA 4LSUG 2NY4A 4R4NA 4DKOA 5F9WA 4DKRA 4R2GA 4RX4E 3SE8G 4LSQG 5FA2A 3IDYA 3NGBA 5F96G 2NY3A 4DVTA 5I9QA 4S1SG 4DVVA 4R4FA 5F4LA 4OLXG 2NY1A 4H8WG 4OM0G 3RJQA 1G9MG 4OLYG 4JKPG 4DKUA 5TE6G 4OM1G 5F4PA 4S1QG 3TGQA 4RFNA 5T33G 3JWDA 4DKQA 4XVSG 4LSRG 3LQAG 4J6RG 4JZWA 4K0AA 1YYLG 1YYMG 1G9NG 2NY2A 4LSSG 4JZZA 4YDKG 2NY6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TGT A;  3HI1 G;  4DVR G;  1RZJ G;  4RWY A;  5CAY G;  4DVS A;  5F4R A;  3JWO A;  4XVT G;  4I53 A;  5TE7 G;  4JM2 E;  2B4C G;  4YE4 G;  1RZK G;  4YDL A;  4RFO G;  4LSV G;  2I5Y G;  3TGS A;  3TIH A;  4DKV A;  4OLZ G;  4P9H G;  5F4U A;  4YFL E;  3TGR A;  2NXZ A;  4XNY G;  2NY7 G;  4I54 A;  5KJR G;  4LSP G;  4S1R G;  3FUS A;  4JPW G;  2BF1 A;  2NY5 G;  4RZ8 A;  5IGX G;  4OLW G;  2I60 G;  3U7Y G;  2NY0 A;  4LST G;  2QAD A;  5F9O G;  5CD5 A;  4OLU G;  4KA2 A;  4JPV G;  1GC1 G;  4XMP G;  4LAJ A;  4YDJ G;  2NXY A;  4DKP A;  3IDX G;  4OLV G;  4JDT G;  4DVW A;  3SE9 G;  4JB9 G;  5TE4 G;  4YDI G;  5FEC C;  4DVX A;  4XNZ A;  4LSU G;  2NY4 A;  4R4N A;  4DKO A;  5F9W A;  4DKR A;  4R2G A;  4RX4 E;  3SE8 G;  4LSQ G;  5FA2 A;  3IDY A;  3NGB A;  5F96 G;  2NY3 A;  4DVT A;  5I9Q A;  4S1S G;  4DVV A;  4R4F A;  5F4L A;  4OLX G;  2NY1 A;  4H8W G;  4OM0 G;  3RJQ A;  1G9M G;  4OLY G;  4JKP G;  4DKU A;  5TE6 G;  4OM1 G;  5F4P A;  4S1Q G;  3TGQ A;  4RFN A;  5T33 G;  3JWD A;  4DKQ A;  4XVS G;  4LSR G;  3LQA G;  4J6R G;  4JZW A;  4K0A A;  1YYL G;  1YYM G;  1G9N G;  2NY2 A;  4LSS G;  4JZZ A;  4YDK G;  2NY6 A; 
#chains in the Genus database with same CATH topology
 3TGT A;  3HI1 G;  4DVR G;  1RZJ G;  4RWY A;  5CAY G;  4DVS A;  5F4R A;  3JWO A;  4XVT G;  4I53 A;  5TE7 G;  4JM2 E;  2B4C G;  4YE4 G;  1RZK G;  4YDL A;  4RFO G;  4LSV G;  2I5Y G;  3TGS A;  3TIH A;  4DKV A;  4OLZ G;  4P9H G;  5F4U A;  4YFL E;  3TGR A;  2NXZ A;  4XNY G;  2NY7 G;  4I54 A;  5KJR G;  4LSP G;  4S1R G;  3FUS A;  4JPW G;  2BF1 A;  2NY5 G;  4RZ8 A;  5IGX G;  4OLW G;  2I60 G;  3U7Y G;  2NY0 A;  4LST G;  2QAD A;  5F9O G;  5CD5 A;  4OLU G;  4KA2 A;  4JPV G;  1GC1 G;  4XMP G;  4LAJ A;  4YDJ G;  2NXY A;  4DKP A;  3IDX G;  4OLV G;  4JDT G;  4DVW A;  3SE9 G;  4JB9 G;  5TE4 G;  4YDI G;  5FEC C;  4DVX A;  4XNZ A;  4LSU G;  2NY4 A;  4R4N A;  4DKO A;  5F9W A;  4DKR A;  4R2G A;  4RX4 E;  3SE8 G;  4LSQ G;  5FA2 A;  3IDY A;  3NGB A;  5F96 G;  2NY3 A;  4DVT A;  5I9Q A;  4S1S G;  4DVV A;  4R4F A;  5F4L A;  4OLX G;  2NY1 A;  4H8W G;  4OM0 G;  3RJQ A;  1G9M G;  4OLY G;  4JKP G;  4DKU A;  5TE6 G;  4OM1 G;  5F4P A;  4S1Q G;  3TGQ A;  4RFN A;  5T33 G;  3JWD A;  4DKQ A;  4XVS G;  4LSR G;  3LQA G;  4J6R G;  4JZW A;  4K0A A;  1YYL G;  1YYM G;  1G9N G;  2NY2 A;  4LSS G;  4JZZ A;  4YDK G;  2NY6 A; 
#chains in the Genus database with same CATH homology
 3TGT A;  3HI1 G;  4DVR G;  1RZJ G;  4RWY A;  5CAY G;  4DVS A;  5F4R A;  3JWO A;  4XVT G;  4I53 A;  5TE7 G;  4JM2 E;  2B4C G;  4YE4 G;  1RZK G;  4YDL A;  4RFO G;  4LSV G;  2I5Y G;  3TGS A;  3TIH A;  4DKV A;  4OLZ G;  4P9H G;  5F4U A;  4YFL E;  3TGR A;  2NXZ A;  4XNY G;  2NY7 G;  4I54 A;  5KJR G;  4LSP G;  4S1R G;  3FUS A;  4JPW G;  2BF1 A;  2NY5 G;  4RZ8 A;  5IGX G;  4OLW G;  2I60 G;  3U7Y G;  2NY0 A;  4LST G;  2QAD A;  5F9O G;  5CD5 A;  4OLU G;  4KA2 A;  4JPV G;  1GC1 G;  4XMP G;  4LAJ A;  4YDJ G;  2NXY A;  4DKP A;  3IDX G;  4OLV G;  4JDT G;  4DVW A;  3SE9 G;  4JB9 G;  5TE4 G;  4YDI G;  5FEC C;  4DVX A;  4XNZ A;  4LSU G;  2NY4 A;  4R4N A;  4DKO A;  5F9W A;  4DKR A;  4R2G A;  4RX4 E;  3SE8 G;  4LSQ G;  5FA2 A;  3IDY A;  3NGB A;  5F96 G;  2NY3 A;  4DVT A;  5I9Q A;  4S1S G;  4DVV A;  4R4F A;  5F4L A;  4OLX G;  2NY1 A;  4H8W G;  4OM0 G;  3RJQ A;  1G9M G;  4OLY G;  4JKP G;  4DKU A;  5TE6 G;  4OM1 G;  5F4P A;  4S1Q G;  3TGQ A;  4RFN A;  5T33 G;  3JWD A;  4DKQ A;  4XVS G;  4LSR G;  3LQA G;  4J6R G;  4JZW A;  4K0A A;  1YYL G;  1YYM G;  1G9N G;  2NY2 A;  4LSS G;  4JZZ A;  4YDK G;  2NY6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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