3TPYA

Crystal structure of m-pmv dutpase with a mixed population of substrate (dupnpp) and post-inversion product (dump) in the active sites
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
113
structure length
113
Chain Sequence
QKQPISKLTRATPGSAGLDLCSTSHTVLTPEMGPQALSTGIYGPLPPNTFGLILGRSSITMKGLQVYPGVIDNDYTGEIKIMAKAVNNIVTVSQGNRIAQLILLPLIETDNKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion
rcsb
molecule tags Hydrolase
source organism Mason-pfizer monkey virus
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDO HYDROLASE
total genus 20
structure length 113
sequence length 113
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2011-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 3tpyA01
3TPYA 4AOZA 1F7DA 3H6XA 1F7OA 1SM8A 3MDXA 3T6YA 1Q5HA 3T60A 3TRLA 3CA9A 3TS6A 1XS1A 2QLPA 3GF0A 1DUDA 4B0HA 4LHRA 3TPSA 2BSYA 2HQUA 2OL0A 1F7RA 3EHWA 3TP1A 3H6DA 2BT1A 4GV8A 2XY3A 2BAZA 3TRNA 3ZF3A 2WE2A 1PKKA 2R9QA 1SNFA 1SMCA 3LOJA 1DUPA 3MBQA 2PY4A 3TTAA 1RNJA 2OKEA 3ZF0A 2OKDA 2WE0A 3TPWA 4AOOA 1F7QA 1Q5UX 1SLHA 3P48A 3C2TA 3ZF2A 3TQ4A 3C3IA 2D4LA 1VYQA 2XCEA 1SIXA 1PKJA 3TQ5A 3TQZA 2J4HA 1SJNA 2V9XA 2Y8CA 3I93A 2D4MA 1EUWA 3ARAA 3T64A 3TSLA 1XS4A 2HXDA 2OKBA 1F7NA 3SO2A 1SEHA 2HR6A 4WRKA 4AO5A 3ZF4A 3F4FA 1XS6A 2HRMA 1PKHA 2QXXA 4OOPA 3TPNA 2HXBA 3ZF6A 5EDDA 1MQ7A 2D4NA 3TQ3A 3ZF5A 4OOQA 1EU5A 2YZJA 1DUCA 5ECTA 2XX6A 2WE1A 5CCTA 3KM3A 2XCDA 4APZ1 3HZAA 3HHQA 3T70A 1RN8A 4GCYA 5CCOA 4A6AA 1OGHA 1SYLA 1DUNA 2PC5A 1DUTA 1F7KA 2OL1A 4XJCA 4DHKA 2WE3A 2ZDCA 2Y1TA 2J4QA 5F9KA 1F7PA 3ZEZA 3LQWA 3ECYA 4GK6A 3ZF1A 3ARNA
chains in the Genus database with same CATH superfamily
3TPYA 4AOZA 1F7DA 3H6XA 1F7OA 1SM8A 3MDXA 3T6YA 1Q5HA 3T60A 3TRLA 3CA9A 3TS6A 1XS1A 2QLPA 3GF0A 1DUDA 4B0HA 4LHRA 3TPSA 2BSYA 2HQUA 2OL0A 1F7RA 3EHWA 3TP1A 3H6DA 2BT1A 4GV8A 2XY3A 2BAZA 3TRNA 3ZF3A 2WE2A 1PKKA 2R9QA 1SNFA 1SMCA 3LOJA 1DUPA 3MBQA 2PY4A 3TTAA 1RNJA 2OKEA 3ZF0A 2OKDA 2WE0A 3TPWA 4AOOA 1F7QA 1Q5UX 1SLHA 3P48A 3C2TA 3ZF2A 3TQ4A 3C3IA 2D4LA 1VYQA 2XCEA 1SIXA 1PKJA 3TQ5A 3TQZA 2J4HA 1SJNA 2V9XA 2Y8CA 3I93A 2D4MA 1EUWA 3ARAA 3T64A 3TSLA 1XS4A 2HXDA 2OKBA 1F7NA 3SO2A 1SEHA 2HR6A 4WRKA 4AO5A 3ZF4A 3F4FA 1XS6A 2HRMA 1PKHA 2QXXA 4OOPA 3TPNA 2HXBA 3ZF6A 5EDDA 1MQ7A 2D4NA 3TQ3A 3ZF5A 4OOQA 1EU5A 2YZJA 1DUCA 5ECTA 2XX6A 2WE1A 5CCTA 3KM3A 2XCDA 4APZ1 3HZAA 3HHQA 3T70A 1RN8A 4GCYA 5CCOA 4A6AA 1OGHA 1SYLA 1DUNA 2PC5A 1DUTA 1F7KA 2OL1A 4XJCA 4DHKA 2WE3A 2ZDCA 1TULA 2Y1TA 2J4QA 5F9KA 1F7PA 3ZEZA 3LQWA 3ECYA 4GK6A 3ZF1A 3ARNA
chains in the Genus database with same CATH topology
3TPYA 4AOZA 1F7DA 3H6XA 1F7OA 1SM8A 3MDXA 3T6YA 1Q5HA 3T60A 3TRLA 3CA9A 3TS6A 1XS1A 2QLPA 3GF0A 1DUDA 4B0HA 4LHRA 3TPSA 2BSYA 2HQUA 2OL0A 1F7RA 3EHWA 3TP1A 3H6DA 2BT1A 4GV8A 2XY3A 2BAZA 3TRNA 3ZF3A 2WE2A 1PKKA 2R9QA 1SNFA 1SMCA 3LOJA 1DUPA 3MBQA 2PY4A 3TTAA 1RNJA 2OKEA 3ZF0A 2OKDA 2WE0A 3TPWA 4AOOA 1F7QA 1Q5UX 1SLHA 3P48A 3C2TA 3ZF2A 3TQ4A 3C3IA 2D4LA 1VYQA 2XCEA 1SIXA 1PKJA 3TQ5A 3TQZA 2J4HA 1SJNA 2V9XA 2Y8CA 3I93A 2D4MA 1EUWA 3ARAA 3T64A 3TSLA 1XS4A 2HXDA 2OKBA 1F7NA 3SO2A 1SEHA 2HR6A 4WRKA 4AO5A 3ZF4A 3F4FA 1XS6A 2HRMA 1PKHA 2QXXA 4OOPA 3TPNA 2HXBA 3ZF6A 5EDDA 1MQ7A 2D4NA 3TQ3A 3ZF5A 4OOQA 1EU5A 2YZJA 1DUCA 5ECTA 2XX6A 2WE1A 5CCTA 3KM3A 2XCDA 4APZ1 3HZAA 3HHQA 3T70A 1RN8A 4GCYA 5CCOA 4A6AA 1OGHA 1SYLA 1DUNA 2PC5A 1DUTA 1F7KA 2OL1A 4XJCA 4DHKA 2WE3A 2ZDCA 2Y1TA 2J4QA 5F9KA 1F7PA 3ZEZA 3LQWA 3ECYA 4GK6A 3ZF1A 3ARNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TPY A;  4AOZ A;  1F7D A;  3H6X A;  1F7O A;  1SM8 A;  3MDX A;  3T6Y A;  1Q5H A;  3T60 A;  3TRL A;  3CA9 A;  3TS6 A;  1XS1 A;  2QLP A;  3GF0 A;  1DUD A;  4B0H A;  4LHR A;  3TPS A;  2BSY A;  2HQU A;  2OL0 A;  1F7R A;  3EHW A;  3TP1 A;  3H6D A;  2BT1 A;  4GV8 A;  2XY3 A;  2BAZ A;  3TRN A;  3ZF3 A;  2WE2 A;  1PKK A;  2R9Q A;  1SNF A;  1SMC A;  3LOJ A;  1DUP A;  3MBQ A;  2PY4 A;  3TTA A;  1RNJ A;  2OKE A;  3ZF0 A;  2OKD A;  2WE0 A;  3TPW A;  4AOO A;  1F7Q A;  1Q5U X;  1SLH A;  3P48 A;  3C2T A;  3ZF2 A;  3TQ4 A;  3C3I A;  2D4L A;  1VYQ A;  2XCE A;  1SIX A;  1PKJ A;  3TQ5 A;  3TQZ A;  2J4H A;  1SJN A;  2V9X A;  2Y8C A;  3I93 A;  2D4M A;  1EUW A;  3ARA A;  3T64 A;  3TSL A;  1XS4 A;  2HXD A;  2OKB A;  1F7N A;  3SO2 A;  1SEH A;  2HR6 A;  4WRK A;  4AO5 A;  3ZF4 A;  3F4F A;  1XS6 A;  2HRM A;  1PKH A;  2QXX A;  4OOP A;  3TPN A;  2HXB A;  3ZF6 A;  5EDD A;  1MQ7 A;  2D4N A;  3TQ3 A;  3ZF5 A;  4OOQ A;  1EU5 A;  2YZJ A;  1DUC A;  5ECT A;  2XX6 A;  2WE1 A;  5CCT A;  3KM3 A;  2XCD A;  4APZ 1;  3HZA A;  3HHQ A;  3T70 A;  1RN8 A;  4GCY A;  5CCO A;  4A6A A;  1OGH A;  1SYL A;  1DUN A;  2PC5 A;  1DUT A;  1F7K A;  2OL1 A;  4XJC A;  4DHK A;  2WE3 A;  2ZDC A;  2Y1T A;  2J4Q A;  5F9K A;  1F7P A;  3ZEZ A;  3LQW A;  3ECY A;  4GK6 A;  3ZF1 A;  3ARN A; 
#chains in the Genus database with same CATH topology
 3TPY A;  4AOZ A;  1F7D A;  3H6X A;  1F7O A;  1SM8 A;  3MDX A;  3T6Y A;  1Q5H A;  3T60 A;  3TRL A;  3CA9 A;  3TS6 A;  1XS1 A;  2QLP A;  3GF0 A;  1DUD A;  4B0H A;  4LHR A;  3TPS A;  2BSY A;  2HQU A;  2OL0 A;  1F7R A;  3EHW A;  3TP1 A;  3H6D A;  2BT1 A;  4GV8 A;  2XY3 A;  2BAZ A;  3TRN A;  3ZF3 A;  2WE2 A;  1PKK A;  2R9Q A;  1SNF A;  1SMC A;  3LOJ A;  1DUP A;  3MBQ A;  2PY4 A;  3TTA A;  1RNJ A;  2OKE A;  3ZF0 A;  2OKD A;  2WE0 A;  3TPW A;  4AOO A;  1F7Q A;  1Q5U X;  1SLH A;  3P48 A;  3C2T A;  3ZF2 A;  3TQ4 A;  3C3I A;  2D4L A;  1VYQ A;  2XCE A;  1SIX A;  1PKJ A;  3TQ5 A;  3TQZ A;  2J4H A;  1SJN A;  2V9X A;  2Y8C A;  3I93 A;  2D4M A;  1EUW A;  3ARA A;  3T64 A;  3TSL A;  1XS4 A;  2HXD A;  2OKB A;  1F7N A;  3SO2 A;  1SEH A;  2HR6 A;  4WRK A;  4AO5 A;  3ZF4 A;  3F4F A;  1XS6 A;  2HRM A;  1PKH A;  2QXX A;  4OOP A;  3TPN A;  2HXB A;  3ZF6 A;  5EDD A;  1MQ7 A;  2D4N A;  3TQ3 A;  3ZF5 A;  4OOQ A;  1EU5 A;  2YZJ A;  1DUC A;  5ECT A;  2XX6 A;  2WE1 A;  5CCT A;  3KM3 A;  2XCD A;  4APZ 1;  3HZA A;  3HHQ A;  3T70 A;  1RN8 A;  4GCY A;  5CCO A;  4A6A A;  1OGH A;  1SYL A;  1DUN A;  2PC5 A;  1DUT A;  1F7K A;  2OL1 A;  4XJC A;  4DHK A;  2WE3 A;  2ZDC A;  1TUL A;  2Y1T A;  2J4Q A;  5F9K A;  1F7P A;  3ZEZ A;  3LQW A;  3ECY A;  4GK6 A;  3ZF1 A;  3ARN A; 
#chains in the Genus database with same CATH homology
 3TPY A;  4AOZ A;  1F7D A;  3H6X A;  1F7O A;  1SM8 A;  3MDX A;  3T6Y A;  1Q5H A;  3T60 A;  3TRL A;  3CA9 A;  3TS6 A;  1XS1 A;  2QLP A;  3GF0 A;  1DUD A;  4B0H A;  4LHR A;  3TPS A;  2BSY A;  2HQU A;  2OL0 A;  1F7R A;  3EHW A;  3TP1 A;  3H6D A;  2BT1 A;  4GV8 A;  2XY3 A;  2BAZ A;  3TRN A;  3ZF3 A;  2WE2 A;  1PKK A;  2R9Q A;  1SNF A;  1SMC A;  3LOJ A;  1DUP A;  3MBQ A;  2PY4 A;  3TTA A;  1RNJ A;  2OKE A;  3ZF0 A;  2OKD A;  2WE0 A;  3TPW A;  4AOO A;  1F7Q A;  1Q5U X;  1SLH A;  3P48 A;  3C2T A;  3ZF2 A;  3TQ4 A;  3C3I A;  2D4L A;  1VYQ A;  2XCE A;  1SIX A;  1PKJ A;  3TQ5 A;  3TQZ A;  2J4H A;  1SJN A;  2V9X A;  2Y8C A;  3I93 A;  2D4M A;  1EUW A;  3ARA A;  3T64 A;  3TSL A;  1XS4 A;  2HXD A;  2OKB A;  1F7N A;  3SO2 A;  1SEH A;  2HR6 A;  4WRK A;  4AO5 A;  3ZF4 A;  3F4F A;  1XS6 A;  2HRM A;  1PKH A;  2QXX A;  4OOP A;  3TPN A;  2HXB A;  3ZF6 A;  5EDD A;  1MQ7 A;  2D4N A;  3TQ3 A;  3ZF5 A;  4OOQ A;  1EU5 A;  2YZJ A;  1DUC A;  5ECT A;  2XX6 A;  2WE1 A;  5CCT A;  3KM3 A;  2XCD A;  4APZ 1;  3HZA A;  3HHQ A;  3T70 A;  1RN8 A;  4GCY A;  5CCO A;  4A6A A;  1OGH A;  1SYL A;  1DUN A;  2PC5 A;  1DUT A;  1F7K A;  2OL1 A;  4XJC A;  4DHK A;  2WE3 A;  2ZDC A;  2Y1T A;  2J4Q A;  5F9K A;  1F7P A;  3ZEZ A;  3LQW A;  3ECY A;  4GK6 A;  3ZF1 A;  3ARN A; 
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similar chains in the Genus database (?% sequence similarity)
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