3TQ3A

Crystal structure of m-pmv dutpase with a mixed population of substrate (dupnpp) and post-inversion product (dump) in the active sites
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
113
structure length
113
Chain Sequence
KQPISKLTRATPGSAGLDLCSTSHTVLTPEMGPQALSTGIYGPLPPNTFGLILGRSSITMKGLQVYPGVIDNDYTGEIKIMAKAVNNIVTVSQGNRIAQLILLPLIETDNKVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion
rcsb
molecule tags Hydrolase
source organism Mason-pfizer monkey virus
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDO HYDROLASE
total genus 20
structure length 113
sequence length 113
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2011-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 3tq3A01
1SIXA 3TQ4A 4APZ1 4XJCA 1MQ7A 3ARNA 3H6XA 1EUWA 1RN8A 3TS6A 1SMCA 3ZF2A 2HRMA 3EHWA 3LQWA 2OL0A 3ARAA 3C2TA 3TPYA 2HXBA 1DUTA 1PKJA 3ZEZA 2XY3A 5CCOA 3SO2A 2PC5A 2YZJA 1F7DA 5ECTA 1F7QA 3HHQA 3ZF3A 2BAZA 1F7NA 3P48A 2WE1A 2HR6A 2D4NA 2WE2A 3ZF4A 3TRLA 1DUCA 3TQ5A 2OKBA 5EDDA 2V9XA 1PKKA 4B0HA 2WE0A 1SM8A 4AOZA 2Y8CA 3MBQA 1DUPA 2XCEA 1F7RA 1XS4A 3TRNA 4A6AA 3TSLA 3C3IA 4DHKA 4AO5A 3TQZA 1SEHA 3CA9A 2D4MA 2J4QA 3TTAA 3ZF6A 4OOQA 1F7OA 2ZDCA 2BSYA 3TPWA 2QLPA 2D4LA 2OKEA 1Q5UX 1RNJA 3MDXA 1SYLA 3T70A 4OOPA 3ZF5A 4WRKA 1DUNA 2J4HA 1SJNA 4AOOA 4GV8A 3HZAA 4GCYA 1XS1A 3TP1A 3F4FA 3TPNA 5F9KA 4GK6A 3TPSA 1OGHA 1SNFA 3ECYA 2OL1A 3ZF1A 1XS6A 3I93A 2HQUA 2BT1A 2XX6A 3TQ3A 2WE3A 4LHRA 2R9QA 3GF0A 3ZF0A 2Y1TA 1VYQA 3T60A 1EU5A 2HXDA 1DUDA 3T6YA 3H6DA 1F7KA 2OKDA 3LOJA 2PY4A 5CCTA 2XCDA 1F7PA 1SLHA 3KM3A 2QXXA 1PKHA 1Q5HA 3T64A
chains in the Genus database with same CATH superfamily
1SIXA 3TQ4A 4APZ1 4XJCA 1MQ7A 3ARNA 3H6XA 1EUWA 1RN8A 3TS6A 1SMCA 3ZF2A 2HRMA 3EHWA 3LQWA 2OL0A 3ARAA 3C2TA 3TPYA 2HXBA 1DUTA 1PKJA 3ZEZA 2XY3A 5CCOA 3SO2A 2PC5A 2YZJA 1F7DA 5ECTA 1F7QA 3HHQA 3ZF3A 2BAZA 1F7NA 3P48A 2WE1A 2HR6A 2D4NA 2WE2A 3ZF4A 3TRLA 1DUCA 3TQ5A 2OKBA 5EDDA 1TULA 2V9XA 1PKKA 4B0HA 2WE0A 1SM8A 4AOZA 2Y8CA 3MBQA 1DUPA 2XCEA 1F7RA 1XS4A 3TRNA 4A6AA 3TSLA 3C3IA 4DHKA 4AO5A 3TQZA 1SEHA 3CA9A 2D4MA 2J4QA 3TTAA 3ZF6A 4OOQA 1F7OA 2ZDCA 2BSYA 3TPWA 2QLPA 2D4LA 2OKEA 1Q5UX 1RNJA 3MDXA 1SYLA 3T70A 4OOPA 3ZF5A 4WRKA 1DUNA 2J4HA 1SJNA 4AOOA 4GV8A 3HZAA 4GCYA 1XS1A 3TP1A 3F4FA 3TPNA 5F9KA 4GK6A 3TPSA 1OGHA 1SNFA 3ECYA 2OL1A 3ZF1A 1XS6A 3I93A 2HQUA 2BT1A 2XX6A 3TQ3A 2WE3A 4LHRA 2R9QA 3GF0A 3ZF0A 2Y1TA 1VYQA 3T60A 1EU5A 2HXDA 1DUDA 3T6YA 3H6DA 1F7KA 2OKDA 3LOJA 2PY4A 5CCTA 2XCDA 1F7PA 1SLHA 3KM3A 2QXXA 1PKHA 1Q5HA 3T64A
chains in the Genus database with same CATH topology
1SIXA 3TQ4A 4APZ1 4XJCA 1MQ7A 3ARNA 3H6XA 1EUWA 1RN8A 3TS6A 1SMCA 3ZF2A 2HRMA 3EHWA 3LQWA 2OL0A 3ARAA 3C2TA 3TPYA 2HXBA 1DUTA 1PKJA 3ZEZA 2XY3A 5CCOA 3SO2A 2PC5A 2YZJA 1F7DA 5ECTA 1F7QA 3HHQA 3ZF3A 2BAZA 1F7NA 3P48A 2WE1A 2HR6A 2D4NA 2WE2A 3ZF4A 3TRLA 1DUCA 3TQ5A 2OKBA 5EDDA 2V9XA 1PKKA 4B0HA 2WE0A 1SM8A 4AOZA 2Y8CA 3MBQA 1DUPA 2XCEA 1F7RA 1XS4A 3TRNA 4A6AA 3TSLA 3C3IA 4DHKA 4AO5A 3TQZA 1SEHA 3CA9A 2D4MA 2J4QA 3TTAA 3ZF6A 4OOQA 1F7OA 2ZDCA 2BSYA 3TPWA 2QLPA 2D4LA 2OKEA 1Q5UX 1RNJA 3MDXA 1SYLA 3T70A 4OOPA 3ZF5A 4WRKA 1DUNA 2J4HA 1SJNA 4AOOA 4GV8A 3HZAA 4GCYA 1XS1A 3TP1A 3F4FA 3TPNA 5F9KA 4GK6A 3TPSA 1OGHA 1SNFA 3ECYA 2OL1A 3ZF1A 1XS6A 3I93A 2HQUA 2BT1A 2XX6A 3TQ3A 2WE3A 4LHRA 2R9QA 3GF0A 3ZF0A 2Y1TA 1VYQA 3T60A 1EU5A 2HXDA 1DUDA 3T6YA 3H6DA 1F7KA 2OKDA 3LOJA 2PY4A 5CCTA 2XCDA 1F7PA 1SLHA 3KM3A 2QXXA 1PKHA 1Q5HA 3T64A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SIX A;  3TQ4 A;  4APZ 1;  4XJC A;  1MQ7 A;  3ARN A;  3H6X A;  1EUW A;  1RN8 A;  3TS6 A;  1SMC A;  3ZF2 A;  2HRM A;  3EHW A;  3LQW A;  2OL0 A;  3ARA A;  3C2T A;  3TPY A;  2HXB A;  1DUT A;  1PKJ A;  3ZEZ A;  2XY3 A;  5CCO A;  3SO2 A;  2PC5 A;  2YZJ A;  1F7D A;  5ECT A;  1F7Q A;  3HHQ A;  3ZF3 A;  2BAZ A;  1F7N A;  3P48 A;  2WE1 A;  2HR6 A;  2D4N A;  2WE2 A;  3ZF4 A;  3TRL A;  1DUC A;  3TQ5 A;  2OKB A;  5EDD A;  2V9X A;  1PKK A;  4B0H A;  2WE0 A;  1SM8 A;  4AOZ A;  2Y8C A;  3MBQ A;  1DUP A;  2XCE A;  1F7R A;  1XS4 A;  3TRN A;  4A6A A;  3TSL A;  3C3I A;  4DHK A;  4AO5 A;  3TQZ A;  1SEH A;  3CA9 A;  2D4M A;  2J4Q A;  3TTA A;  3ZF6 A;  4OOQ A;  1F7O A;  2ZDC A;  2BSY A;  3TPW A;  2QLP A;  2D4L A;  2OKE A;  1Q5U X;  1RNJ A;  3MDX A;  1SYL A;  3T70 A;  4OOP A;  3ZF5 A;  4WRK A;  1DUN A;  2J4H A;  1SJN A;  4AOO A;  4GV8 A;  3HZA A;  4GCY A;  1XS1 A;  3TP1 A;  3F4F A;  3TPN A;  5F9K A;  4GK6 A;  3TPS A;  1OGH A;  1SNF A;  3ECY A;  2OL1 A;  3ZF1 A;  1XS6 A;  3I93 A;  2HQU A;  2BT1 A;  2XX6 A;  3TQ3 A;  2WE3 A;  4LHR A;  2R9Q A;  3GF0 A;  3ZF0 A;  2Y1T A;  1VYQ A;  3T60 A;  1EU5 A;  2HXD A;  1DUD A;  3T6Y A;  3H6D A;  1F7K A;  2OKD A;  3LOJ A;  2PY4 A;  5CCT A;  2XCD A;  1F7P A;  1SLH A;  3KM3 A;  2QXX A;  1PKH A;  1Q5H A;  3T64 A; 
#chains in the Genus database with same CATH topology
 1SIX A;  3TQ4 A;  4APZ 1;  4XJC A;  1MQ7 A;  3ARN A;  3H6X A;  1EUW A;  1RN8 A;  3TS6 A;  1SMC A;  3ZF2 A;  2HRM A;  3EHW A;  3LQW A;  2OL0 A;  3ARA A;  3C2T A;  3TPY A;  2HXB A;  1DUT A;  1PKJ A;  3ZEZ A;  2XY3 A;  5CCO A;  3SO2 A;  2PC5 A;  2YZJ A;  1F7D A;  5ECT A;  1F7Q A;  3HHQ A;  3ZF3 A;  2BAZ A;  1F7N A;  3P48 A;  2WE1 A;  2HR6 A;  2D4N A;  2WE2 A;  3ZF4 A;  3TRL A;  1DUC A;  3TQ5 A;  2OKB A;  5EDD A;  1TUL A;  2V9X A;  1PKK A;  4B0H A;  2WE0 A;  1SM8 A;  4AOZ A;  2Y8C A;  3MBQ A;  1DUP A;  2XCE A;  1F7R A;  1XS4 A;  3TRN A;  4A6A A;  3TSL A;  3C3I A;  4DHK A;  4AO5 A;  3TQZ A;  1SEH A;  3CA9 A;  2D4M A;  2J4Q A;  3TTA A;  3ZF6 A;  4OOQ A;  1F7O A;  2ZDC A;  2BSY A;  3TPW A;  2QLP A;  2D4L A;  2OKE A;  1Q5U X;  1RNJ A;  3MDX A;  1SYL A;  3T70 A;  4OOP A;  3ZF5 A;  4WRK A;  1DUN A;  2J4H A;  1SJN A;  4AOO A;  4GV8 A;  3HZA A;  4GCY A;  1XS1 A;  3TP1 A;  3F4F A;  3TPN A;  5F9K A;  4GK6 A;  3TPS A;  1OGH A;  1SNF A;  3ECY A;  2OL1 A;  3ZF1 A;  1XS6 A;  3I93 A;  2HQU A;  2BT1 A;  2XX6 A;  3TQ3 A;  2WE3 A;  4LHR A;  2R9Q A;  3GF0 A;  3ZF0 A;  2Y1T A;  1VYQ A;  3T60 A;  1EU5 A;  2HXD A;  1DUD A;  3T6Y A;  3H6D A;  1F7K A;  2OKD A;  3LOJ A;  2PY4 A;  5CCT A;  2XCD A;  1F7P A;  1SLH A;  3KM3 A;  2QXX A;  1PKH A;  1Q5H A;  3T64 A; 
#chains in the Genus database with same CATH homology
 1SIX A;  3TQ4 A;  4APZ 1;  4XJC A;  1MQ7 A;  3ARN A;  3H6X A;  1EUW A;  1RN8 A;  3TS6 A;  1SMC A;  3ZF2 A;  2HRM A;  3EHW A;  3LQW A;  2OL0 A;  3ARA A;  3C2T A;  3TPY A;  2HXB A;  1DUT A;  1PKJ A;  3ZEZ A;  2XY3 A;  5CCO A;  3SO2 A;  2PC5 A;  2YZJ A;  1F7D A;  5ECT A;  1F7Q A;  3HHQ A;  3ZF3 A;  2BAZ A;  1F7N A;  3P48 A;  2WE1 A;  2HR6 A;  2D4N A;  2WE2 A;  3ZF4 A;  3TRL A;  1DUC A;  3TQ5 A;  2OKB A;  5EDD A;  2V9X A;  1PKK A;  4B0H A;  2WE0 A;  1SM8 A;  4AOZ A;  2Y8C A;  3MBQ A;  1DUP A;  2XCE A;  1F7R A;  1XS4 A;  3TRN A;  4A6A A;  3TSL A;  3C3I A;  4DHK A;  4AO5 A;  3TQZ A;  1SEH A;  3CA9 A;  2D4M A;  2J4Q A;  3TTA A;  3ZF6 A;  4OOQ A;  1F7O A;  2ZDC A;  2BSY A;  3TPW A;  2QLP A;  2D4L A;  2OKE A;  1Q5U X;  1RNJ A;  3MDX A;  1SYL A;  3T70 A;  4OOP A;  3ZF5 A;  4WRK A;  1DUN A;  2J4H A;  1SJN A;  4AOO A;  4GV8 A;  3HZA A;  4GCY A;  1XS1 A;  3TP1 A;  3F4F A;  3TPN A;  5F9K A;  4GK6 A;  3TPS A;  1OGH A;  1SNF A;  3ECY A;  2OL1 A;  3ZF1 A;  1XS6 A;  3I93 A;  2HQU A;  2BT1 A;  2XX6 A;  3TQ3 A;  2WE3 A;  4LHR A;  2R9Q A;  3GF0 A;  3ZF0 A;  2Y1T A;  1VYQ A;  3T60 A;  1EU5 A;  2HXD A;  1DUD A;  3T6Y A;  3H6D A;  1F7K A;  2OKD A;  3LOJ A;  2PY4 A;  5CCT A;  2XCD A;  1F7P A;  1SLH A;  3KM3 A;  2QXX A;  1PKH A;  1Q5H A;  3T64 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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