3TQ4A

Crystal structure of m-pmv dutpase with a mixed population of substrate (dupnpp) and post-inversion product (dump) in the active sites
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
112
structure length
112
Chain Sequence
KQPISKLTRATPGSAGLDLCSTSHTVLTPEMGPQALSTGIYGPLPPNTFGLILGRSSITMKGLQVYPGVIDNDYTGEIKIMAKAVNNIVTVSQGNRIAQLILLPLIETDNKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion
rcsb
molecule tags Hydrolase
source organism Mason-pfizer monkey virus
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDO HYDROLASE
total genus 20
structure length 112
sequence length 112
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2011-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 3tq4A01
3ZF2A 2HR6A 4B0HA 2XY3A 2BAZA 2OL0A 2J4HA 3I93A 3T6YA 2HXBA 3C2TA 4GCYA 1VYQA 1SMCA 1XS1A 2V9XA 3T64A 3TPNA 2R9QA 3EHWA 5F9KA 1XS4A 3ARNA 2HXDA 1SIXA 1SJNA 4OOPA 1OGHA 2OKEA 3ZF3A 3TQ5A 2QXXA 3ARAA 4APZ1 1MQ7A 1PKHA 2D4NA 5EDDA 3GF0A 1F7NA 3MDXA 2OL1A 2HQUA 3TPWA 3T70A 3TRLA 3LOJA 1F7KA 2QLPA 3ZEZA 1DUCA 3LQWA 3ZF4A 2Y1TA 1SLHA 3TSLA 2J4QA 1F7OA 3H6XA 3T60A 3TPSA 3TPYA 1SYLA 1PKJA 3TQ4A 4A6AA 5ECTA 3CA9A 3ZF0A 4LHRA 3KM3A 3TQ3A 1SNFA 2D4LA 1DUPA 1Q5UX 3ZF1A 3ZF5A 1DUDA 1SM8A 3P48A 2Y8CA 3MBQA 2YZJA 2BT1A 4AOOA 4XJCA 4GV8A 1F7DA 1SEHA 4AO5A 3C3IA 3SO2A 3HHQA 5CCOA 3H6DA 2BSYA 2OKBA 5CCTA 1Q5HA 3TRNA 1F7PA 2D4MA 4OOQA 2WE1A 3TP1A 3TS6A 1F7RA 2PC5A 3ECYA 1RN8A 3TTAA 2WE0A 2XCDA 1EUWA 4AOZA 2OKDA 2WE2A 1F7QA 3ZF6A 2PY4A 4WRKA 1XS6A 1EU5A 1PKKA 3F4FA 3HZAA 2XCEA 2ZDCA 3TQZA 2WE3A 2XX6A 2HRMA 1DUNA 1RNJA 4GK6A 4DHKA 1DUTA
chains in the Genus database with same CATH superfamily
3ZF2A 2HR6A 4B0HA 2XY3A 2BAZA 2OL0A 2J4HA 3I93A 3T6YA 2HXBA 3C2TA 4GCYA 1VYQA 1SMCA 1XS1A 2V9XA 3T64A 3TPNA 2R9QA 3EHWA 5F9KA 1XS4A 3ARNA 2HXDA 1SIXA 1SJNA 4OOPA 1OGHA 2OKEA 3ZF3A 3TQ5A 2QXXA 3ARAA 4APZ1 1MQ7A 1PKHA 2D4NA 5EDDA 3GF0A 1F7NA 3MDXA 2OL1A 2HQUA 3TPWA 3T70A 3TRLA 3LOJA 1F7KA 2QLPA 3ZEZA 1DUCA 3LQWA 3ZF4A 2Y1TA 1SLHA 3TSLA 2J4QA 1F7OA 3H6XA 3T60A 3TPSA 3TPYA 1SYLA 1PKJA 3TQ4A 4A6AA 5ECTA 3CA9A 3ZF0A 4LHRA 3KM3A 3TQ3A 1SNFA 1TULA 2D4LA 1DUPA 1Q5UX 3ZF1A 3ZF5A 1DUDA 1SM8A 3P48A 2Y8CA 3MBQA 2YZJA 2BT1A 4AOOA 4XJCA 4GV8A 1F7DA 1SEHA 4AO5A 3C3IA 3SO2A 3HHQA 5CCOA 3H6DA 2BSYA 2OKBA 5CCTA 1Q5HA 3TRNA 1F7PA 2D4MA 4OOQA 2WE1A 3TP1A 3TS6A 1F7RA 2PC5A 3ECYA 1RN8A 3TTAA 2WE0A 2XCDA 1EUWA 4AOZA 2OKDA 2WE2A 1F7QA 3ZF6A 2PY4A 4WRKA 1XS6A 1EU5A 1PKKA 3F4FA 3HZAA 2XCEA 2ZDCA 3TQZA 2WE3A 2XX6A 2HRMA 1DUNA 1RNJA 4GK6A 4DHKA 1DUTA
chains in the Genus database with same CATH topology
3ZF2A 2HR6A 4B0HA 2XY3A 2BAZA 2OL0A 2J4HA 3I93A 3T6YA 2HXBA 3C2TA 4GCYA 1VYQA 1SMCA 1XS1A 2V9XA 3T64A 3TPNA 2R9QA 3EHWA 5F9KA 1XS4A 3ARNA 2HXDA 1SIXA 1SJNA 4OOPA 1OGHA 2OKEA 3ZF3A 3TQ5A 2QXXA 3ARAA 4APZ1 1MQ7A 1PKHA 2D4NA 5EDDA 3GF0A 1F7NA 3MDXA 2OL1A 2HQUA 3TPWA 3T70A 3TRLA 3LOJA 1F7KA 2QLPA 3ZEZA 1DUCA 3LQWA 3ZF4A 2Y1TA 1SLHA 3TSLA 2J4QA 1F7OA 3H6XA 3T60A 3TPSA 3TPYA 1SYLA 1PKJA 3TQ4A 4A6AA 5ECTA 3CA9A 3ZF0A 4LHRA 3KM3A 3TQ3A 1SNFA 2D4LA 1DUPA 1Q5UX 3ZF1A 3ZF5A 1DUDA 1SM8A 3P48A 2Y8CA 3MBQA 2YZJA 2BT1A 4AOOA 4XJCA 4GV8A 1F7DA 1SEHA 4AO5A 3C3IA 3SO2A 3HHQA 5CCOA 3H6DA 2BSYA 2OKBA 5CCTA 1Q5HA 3TRNA 1F7PA 2D4MA 4OOQA 2WE1A 3TP1A 3TS6A 1F7RA 2PC5A 3ECYA 1RN8A 3TTAA 2WE0A 2XCDA 1EUWA 4AOZA 2OKDA 2WE2A 1F7QA 3ZF6A 2PY4A 4WRKA 1XS6A 1EU5A 1PKKA 3F4FA 3HZAA 2XCEA 2ZDCA 3TQZA 2WE3A 2XX6A 2HRMA 1DUNA 1RNJA 4GK6A 4DHKA 1DUTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZF2 A;  2HR6 A;  4B0H A;  2XY3 A;  2BAZ A;  2OL0 A;  2J4H A;  3I93 A;  3T6Y A;  2HXB A;  3C2T A;  4GCY A;  1VYQ A;  1SMC A;  1XS1 A;  2V9X A;  3T64 A;  3TPN A;  2R9Q A;  3EHW A;  5F9K A;  1XS4 A;  3ARN A;  2HXD A;  1SIX A;  1SJN A;  4OOP A;  1OGH A;  2OKE A;  3ZF3 A;  3TQ5 A;  2QXX A;  3ARA A;  4APZ 1;  1MQ7 A;  1PKH A;  2D4N A;  5EDD A;  3GF0 A;  1F7N A;  3MDX A;  2OL1 A;  2HQU A;  3TPW A;  3T70 A;  3TRL A;  3LOJ A;  1F7K A;  2QLP A;  3ZEZ A;  1DUC A;  3LQW A;  3ZF4 A;  2Y1T A;  1SLH A;  3TSL A;  2J4Q A;  1F7O A;  3H6X A;  3T60 A;  3TPS A;  3TPY A;  1SYL A;  1PKJ A;  3TQ4 A;  4A6A A;  5ECT A;  3CA9 A;  3ZF0 A;  4LHR A;  3KM3 A;  3TQ3 A;  1SNF A;  2D4L A;  1DUP A;  1Q5U X;  3ZF1 A;  3ZF5 A;  1DUD A;  1SM8 A;  3P48 A;  2Y8C A;  3MBQ A;  2YZJ A;  2BT1 A;  4AOO A;  4XJC A;  4GV8 A;  1F7D A;  1SEH A;  4AO5 A;  3C3I A;  3SO2 A;  3HHQ A;  5CCO A;  3H6D A;  2BSY A;  2OKB A;  5CCT A;  1Q5H A;  3TRN A;  1F7P A;  2D4M A;  4OOQ A;  2WE1 A;  3TP1 A;  3TS6 A;  1F7R A;  2PC5 A;  3ECY A;  1RN8 A;  3TTA A;  2WE0 A;  2XCD A;  1EUW A;  4AOZ A;  2OKD A;  2WE2 A;  1F7Q A;  3ZF6 A;  2PY4 A;  4WRK A;  1XS6 A;  1EU5 A;  1PKK A;  3F4F A;  3HZA A;  2XCE A;  2ZDC A;  3TQZ A;  2WE3 A;  2XX6 A;  2HRM A;  1DUN A;  1RNJ A;  4GK6 A;  4DHK A;  1DUT A; 
#chains in the Genus database with same CATH topology
 3ZF2 A;  2HR6 A;  4B0H A;  2XY3 A;  2BAZ A;  2OL0 A;  2J4H A;  3I93 A;  3T6Y A;  2HXB A;  3C2T A;  4GCY A;  1VYQ A;  1SMC A;  1XS1 A;  2V9X A;  3T64 A;  3TPN A;  2R9Q A;  3EHW A;  5F9K A;  1XS4 A;  3ARN A;  2HXD A;  1SIX A;  1SJN A;  4OOP A;  1OGH A;  2OKE A;  3ZF3 A;  3TQ5 A;  2QXX A;  3ARA A;  4APZ 1;  1MQ7 A;  1PKH A;  2D4N A;  5EDD A;  3GF0 A;  1F7N A;  3MDX A;  2OL1 A;  2HQU A;  3TPW A;  3T70 A;  3TRL A;  3LOJ A;  1F7K A;  2QLP A;  3ZEZ A;  1DUC A;  3LQW A;  3ZF4 A;  2Y1T A;  1SLH A;  3TSL A;  2J4Q A;  1F7O A;  3H6X A;  3T60 A;  3TPS A;  3TPY A;  1SYL A;  1PKJ A;  3TQ4 A;  4A6A A;  5ECT A;  3CA9 A;  3ZF0 A;  4LHR A;  3KM3 A;  3TQ3 A;  1SNF A;  1TUL A;  2D4L A;  1DUP A;  1Q5U X;  3ZF1 A;  3ZF5 A;  1DUD A;  1SM8 A;  3P48 A;  2Y8C A;  3MBQ A;  2YZJ A;  2BT1 A;  4AOO A;  4XJC A;  4GV8 A;  1F7D A;  1SEH A;  4AO5 A;  3C3I A;  3SO2 A;  3HHQ A;  5CCO A;  3H6D A;  2BSY A;  2OKB A;  5CCT A;  1Q5H A;  3TRN A;  1F7P A;  2D4M A;  4OOQ A;  2WE1 A;  3TP1 A;  3TS6 A;  1F7R A;  2PC5 A;  3ECY A;  1RN8 A;  3TTA A;  2WE0 A;  2XCD A;  1EUW A;  4AOZ A;  2OKD A;  2WE2 A;  1F7Q A;  3ZF6 A;  2PY4 A;  4WRK A;  1XS6 A;  1EU5 A;  1PKK A;  3F4F A;  3HZA A;  2XCE A;  2ZDC A;  3TQZ A;  2WE3 A;  2XX6 A;  2HRM A;  1DUN A;  1RNJ A;  4GK6 A;  4DHK A;  1DUT A; 
#chains in the Genus database with same CATH homology
 3ZF2 A;  2HR6 A;  4B0H A;  2XY3 A;  2BAZ A;  2OL0 A;  2J4H A;  3I93 A;  3T6Y A;  2HXB A;  3C2T A;  4GCY A;  1VYQ A;  1SMC A;  1XS1 A;  2V9X A;  3T64 A;  3TPN A;  2R9Q A;  3EHW A;  5F9K A;  1XS4 A;  3ARN A;  2HXD A;  1SIX A;  1SJN A;  4OOP A;  1OGH A;  2OKE A;  3ZF3 A;  3TQ5 A;  2QXX A;  3ARA A;  4APZ 1;  1MQ7 A;  1PKH A;  2D4N A;  5EDD A;  3GF0 A;  1F7N A;  3MDX A;  2OL1 A;  2HQU A;  3TPW A;  3T70 A;  3TRL A;  3LOJ A;  1F7K A;  2QLP A;  3ZEZ A;  1DUC A;  3LQW A;  3ZF4 A;  2Y1T A;  1SLH A;  3TSL A;  2J4Q A;  1F7O A;  3H6X A;  3T60 A;  3TPS A;  3TPY A;  1SYL A;  1PKJ A;  3TQ4 A;  4A6A A;  5ECT A;  3CA9 A;  3ZF0 A;  4LHR A;  3KM3 A;  3TQ3 A;  1SNF A;  2D4L A;  1DUP A;  1Q5U X;  3ZF1 A;  3ZF5 A;  1DUD A;  1SM8 A;  3P48 A;  2Y8C A;  3MBQ A;  2YZJ A;  2BT1 A;  4AOO A;  4XJC A;  4GV8 A;  1F7D A;  1SEH A;  4AO5 A;  3C3I A;  3SO2 A;  3HHQ A;  5CCO A;  3H6D A;  2BSY A;  2OKB A;  5CCT A;  1Q5H A;  3TRN A;  1F7P A;  2D4M A;  4OOQ A;  2WE1 A;  3TP1 A;  3TS6 A;  1F7R A;  2PC5 A;  3ECY A;  1RN8 A;  3TTA A;  2WE0 A;  2XCD A;  1EUW A;  4AOZ A;  2OKD A;  2WE2 A;  1F7Q A;  3ZF6 A;  2PY4 A;  4WRK A;  1XS6 A;  1EU5 A;  1PKK A;  3F4F A;  3HZA A;  2XCE A;  2ZDC A;  3TQZ A;  2WE3 A;  2XX6 A;  2HRM A;  1DUN A;  1RNJ A;  4GK6 A;  4DHK A;  1DUT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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