3U7KA

Crystal structures of the staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
185
structure length
184
Chain Sequence
MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKDHPLQPHTDAVEVLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Staphylococcus aureus
molecule keywords Peptide deformylase
total genus 51
structure length 184
sequence length 185
ec nomenclature ec 3.5.1.88: Peptide deformylase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01327 Pep_deformylase Polypeptide deformylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.45.10 Alpha Beta Alpha-Beta Complex Peptide Deformylase Peptide deformylase 3u7kA00
2OS1A 5CVQA 5JF4A 5CY8A 4DR8A 3PN4A 5CWYA 3G5PA 4AZ4A 2DEFA 1SZZA 3PN2A 1LMHA 5J46A 4E9BA 2OS3A 3M6QA 3M6RA 1VEZA 2OS0A 1SV2A 2EW6A 2AIAA 2AI7A 4EOXP 3U04A 1VEVA 2W3UA 1BSJA 5JF0A 5JF7A 1BS4A 3SW8P 1LRYA 5KOBA 2AI9A 3M6OA 5CXJA 5JEXA 1LQYA 3U7MA 1BSZA 1XENA 3UWBA 3M6PA 4WXKA 3K6LA 1LM4A 5JF6A 1ZY1A 1LMEA 3U7LA 1WS1A 3E3UA 3SVJP 5I2BA 1RQCA 3U7KA 1LRUA 5CY7A 5JF8A 1XEMA 1ICJA 5CWXA 1LQWA 2W3TA 4E9AA 4JE7A 5JF1A 1RL4A 3OCAA 4WXLA 1WS0A 5JEYA 1Y6HA 1ZY0A 2AI8A 1BS8A 5CPDA 4NT8A 5CP0A 3STRP 1G2AA 2EW7A 1VEYA 4JE6A 4AL3A 3PN6A 3QU1A 2EW5A 5CVKA 1JYMA 5CX0A 3G5KA 5JEZA 1BS6A 1DEFA 3PN3A 5JF2A 1ZXZA 3CPMA 5T8ZA 1BS7A 1DFFA 1N5NA 5JF3A 1BS5A 3O3JA 1G27A 2OKLA 2KMNA 3PN5A 1BSKA 3CMDA 4AL2A 1Q1YA 5HGWA 1LM6A 5JF5A 5CVPA 1XEOA 2AIEP 3FWXA 3G6NA 4DR9A 3UWAA 5E5DA 4JE8A 3L87A 1V3YA 1S17A 1IX1A 3U7NA
chains in the Genus database with same CATH superfamily
2OS1A 5CVQA 5JF4A 5CY8A 4DR8A 3PN4A 5CWYA 3G5PA 4AZ4A 2DEFA 1SZZA 3PN2A 1LMHA 5J46A 4E9BA 2OS3A 3M6QA 3M6RA 1VEZA 2OS0A 1SV2A 2EW6A 2AIAA 2AI7A 4EOXP 3U04A 1VEVA 2W3UA 1BSJA 5JF0A 5JF7A 1BS4A 3SW8P 1LRYA 5KOBA 2AI9A 3M6OA 5CXJA 5JEXA 1LQYA 3U7MA 1BSZA 1XENA 3UWBA 3M6PA 4WXKA 3K6LA 1LM4A 5JF6A 1ZY1A 1LMEA 3U7LA 1WS1A 3E3UA 3SVJP 5I2BA 1RQCA 3U7KA 1LRUA 5CY7A 5JF8A 1XEMA 1ICJA 5CWXA 1LQWA 2W3TA 4E9AA 4JE7A 5JF1A 1RL4A 3OCAA 4WXLA 1WS0A 5JEYA 1Y6HA 1ZY0A 2AI8A 1BS8A 5CPDA 4NT8A 5CP0A 3STRP 1G2AA 2EW7A 1VEYA 4JE6A 4AL3A 3PN6A 3QU1A 2EW5A 5CVKA 1JYMA 5CX0A 3G5KA 5JEZA 1BS6A 1DEFA 3PN3A 5JF2A 1ZXZA 3CPMA 5T8ZA 1BS7A 1DFFA 1N5NA 5JF3A 1BS5A 3O3JA 1G27A 2OKLA 2KMNA 3PN5A 1BSKA 3CMDA 4AL2A 1Q1YA 5HGWA 1LM6A 5JF5A 5CVPA 1XEOA 2AIEP 3FWXA 3G6NA 4DR9A 3UWAA 5E5DA 4JE8A 3L87A 1V3YA 1S17A 1IX1A 3U7NA
chains in the Genus database with same CATH topology
2OS1A 5CVQA 5JF4A 5CY8A 4DR8A 3PN4A 5CWYA 3G5PA 4AZ4A 2DEFA 1SZZA 3PN2A 1LMHA 5J46A 4E9BA 2OS3A 3M6QA 3M6RA 1VEZA 2OS0A 1SV2A 2EW6A 2AIAA 2AI7A 4EOXP 3U04A 1VEVA 2W3UA 1BSJA 5JF0A 5JF7A 1BS4A 3SW8P 1LRYA 5KOBA 2AI9A 3M6OA 5CXJA 5JEXA 1LQYA 3U7MA 1BSZA 1XENA 3UWBA 3M6PA 4WXKA 3K6LA 1LM4A 5JF6A 1ZY1A 1LMEA 3U7LA 1WS1A 3E3UA 3SVJP 5I2BA 1RQCA 3U7KA 1LRUA 5CY7A 5JF8A 1XEMA 1ICJA 5CWXA 1LQWA 2W3TA 4E9AA 4JE7A 5JF1A 1RL4A 3OCAA 4WXLA 1WS0A 5JEYA 1Y6HA 1ZY0A 2AI8A 1BS8A 5CPDA 4NT8A 5CP0A 3STRP 1G2AA 2EW7A 1VEYA 4JE6A 4AL3A 3PN6A 3QU1A 2EW5A 5CVKA 1JYMA 5CX0A 3G5KA 5JEZA 1BS6A 1DEFA 3PN3A 5JF2A 1ZXZA 3CPMA 5T8ZA 1BS7A 1DFFA 1N5NA 5JF3A 1BS5A 3O3JA 1G27A 2OKLA 2KMNA 3PN5A 1BSKA 3CMDA 4AL2A 1Q1YA 5HGWA 1LM6A 5JF5A 5CVPA 1XEOA 2AIEP 3FWXA 3G6NA 4DR9A 3UWAA 5E5DA 4JE8A 3L87A 1V3YA 1S17A 1IX1A 3U7NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OS1 A;  5CVQ A;  5JF4 A;  5CY8 A;  4DR8 A;  3PN4 A;  5CWY A;  3G5P A;  4AZ4 A;  2DEF A;  1SZZ A;  3PN2 A;  1LMH A;  5J46 A;  4E9B A;  2OS3 A;  3M6Q A;  3M6R A;  1VEZ A;  2OS0 A;  1SV2 A;  2EW6 A;  2AIA A;  2AI7 A;  4EOX P;  3U04 A;  1VEV A;  2W3U A;  1BSJ A;  5JF0 A;  5JF7 A;  1BS4 A;  3SW8 P;  1LRY A;  5KOB A;  2AI9 A;  3M6O A;  5CXJ A;  5JEX A;  1LQY A;  3U7M A;  1BSZ A;  1XEN A;  3UWB A;  3M6P A;  4WXK A;  3K6L A;  1LM4 A;  5JF6 A;  1ZY1 A;  1LME A;  3U7L A;  1WS1 A;  3E3U A;  3SVJ P;  5I2B A;  1RQC A;  3U7K A;  1LRU A;  5CY7 A;  5JF8 A;  1XEM A;  1ICJ A;  5CWX A;  1LQW A;  2W3T A;  4E9A A;  4JE7 A;  5JF1 A;  1RL4 A;  3OCA A;  4WXL A;  1WS0 A;  5JEY A;  1Y6H A;  1ZY0 A;  2AI8 A;  1BS8 A;  5CPD A;  4NT8 A;  5CP0 A;  3STR P;  1G2A A;  2EW7 A;  1VEY A;  4JE6 A;  4AL3 A;  3PN6 A;  3QU1 A;  2EW5 A;  5CVK A;  1JYM A;  5CX0 A;  3G5K A;  5JEZ A;  1BS6 A;  1DEF A;  3PN3 A;  5JF2 A;  1ZXZ A;  3CPM A;  5T8Z A;  1BS7 A;  1DFF A;  1N5N A;  5JF3 A;  1BS5 A;  3O3J A;  1G27 A;  2OKL A;  2KMN A;  3PN5 A;  1BSK A;  3CMD A;  4AL2 A;  1Q1Y A;  5HGW A;  1LM6 A;  5JF5 A;  5CVP A;  1XEO A;  2AIE P;  3FWX A;  3G6N A;  4DR9 A;  3UWA A;  5E5D A;  4JE8 A;  3L87 A;  1V3Y A;  1S17 A;  1IX1 A;  3U7N A; 
#chains in the Genus database with same CATH topology
 2OS1 A;  5CVQ A;  5JF4 A;  5CY8 A;  4DR8 A;  3PN4 A;  5CWY A;  3G5P A;  4AZ4 A;  2DEF A;  1SZZ A;  3PN2 A;  1LMH A;  5J46 A;  4E9B A;  2OS3 A;  3M6Q A;  3M6R A;  1VEZ A;  2OS0 A;  1SV2 A;  2EW6 A;  2AIA A;  2AI7 A;  4EOX P;  3U04 A;  1VEV A;  2W3U A;  1BSJ A;  5JF0 A;  5JF7 A;  1BS4 A;  3SW8 P;  1LRY A;  5KOB A;  2AI9 A;  3M6O A;  5CXJ A;  5JEX A;  1LQY A;  3U7M A;  1BSZ A;  1XEN A;  3UWB A;  3M6P A;  4WXK A;  3K6L A;  1LM4 A;  5JF6 A;  1ZY1 A;  1LME A;  3U7L A;  1WS1 A;  3E3U A;  3SVJ P;  5I2B A;  1RQC A;  3U7K A;  1LRU A;  5CY7 A;  5JF8 A;  1XEM A;  1ICJ A;  5CWX A;  1LQW A;  2W3T A;  4E9A A;  4JE7 A;  5JF1 A;  1RL4 A;  3OCA A;  4WXL A;  1WS0 A;  5JEY A;  1Y6H A;  1ZY0 A;  2AI8 A;  1BS8 A;  5CPD A;  4NT8 A;  5CP0 A;  3STR P;  1G2A A;  2EW7 A;  1VEY A;  4JE6 A;  4AL3 A;  3PN6 A;  3QU1 A;  2EW5 A;  5CVK A;  1JYM A;  5CX0 A;  3G5K A;  5JEZ A;  1BS6 A;  1DEF A;  3PN3 A;  5JF2 A;  1ZXZ A;  3CPM A;  5T8Z A;  1BS7 A;  1DFF A;  1N5N A;  5JF3 A;  1BS5 A;  3O3J A;  1G27 A;  2OKL A;  2KMN A;  3PN5 A;  1BSK A;  3CMD A;  4AL2 A;  1Q1Y A;  5HGW A;  1LM6 A;  5JF5 A;  5CVP A;  1XEO A;  2AIE P;  3FWX A;  3G6N A;  4DR9 A;  3UWA A;  5E5D A;  4JE8 A;  3L87 A;  1V3Y A;  1S17 A;  1IX1 A;  3U7N A; 
#chains in the Genus database with same CATH homology
 2OS1 A;  5CVQ A;  5JF4 A;  5CY8 A;  4DR8 A;  3PN4 A;  5CWY A;  3G5P A;  4AZ4 A;  2DEF A;  1SZZ A;  3PN2 A;  1LMH A;  5J46 A;  4E9B A;  2OS3 A;  3M6Q A;  3M6R A;  1VEZ A;  2OS0 A;  1SV2 A;  2EW6 A;  2AIA A;  2AI7 A;  4EOX P;  3U04 A;  1VEV A;  2W3U A;  1BSJ A;  5JF0 A;  5JF7 A;  1BS4 A;  3SW8 P;  1LRY A;  5KOB A;  2AI9 A;  3M6O A;  5CXJ A;  5JEX A;  1LQY A;  3U7M A;  1BSZ A;  1XEN A;  3UWB A;  3M6P A;  4WXK A;  3K6L A;  1LM4 A;  5JF6 A;  1ZY1 A;  1LME A;  3U7L A;  1WS1 A;  3E3U A;  3SVJ P;  5I2B A;  1RQC A;  3U7K A;  1LRU A;  5CY7 A;  5JF8 A;  1XEM A;  1ICJ A;  5CWX A;  1LQW A;  2W3T A;  4E9A A;  4JE7 A;  5JF1 A;  1RL4 A;  3OCA A;  4WXL A;  1WS0 A;  5JEY A;  1Y6H A;  1ZY0 A;  2AI8 A;  1BS8 A;  5CPD A;  4NT8 A;  5CP0 A;  3STR P;  1G2A A;  2EW7 A;  1VEY A;  4JE6 A;  4AL3 A;  3PN6 A;  3QU1 A;  2EW5 A;  5CVK A;  1JYM A;  5CX0 A;  3G5K A;  5JEZ A;  1BS6 A;  1DEF A;  3PN3 A;  5JF2 A;  1ZXZ A;  3CPM A;  5T8Z A;  1BS7 A;  1DFF A;  1N5N A;  5JF3 A;  1BS5 A;  3O3J A;  1G27 A;  2OKL A;  2KMN A;  3PN5 A;  1BSK A;  3CMD A;  4AL2 A;  1Q1Y A;  5HGW A;  1LM6 A;  5JF5 A;  5CVP A;  1XEO A;  2AIE P;  3FWX A;  3G6N A;  4DR9 A;  3UWA A;  5E5D A;  4JE8 A;  3L87 A;  1V3Y A;  1S17 A;  1IX1 A;  3U7N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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