3U7LA

Crystal structures of the staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Total Genus 52
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
185
structure length
184
Chain Sequence
MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKDHPLQPHTDAVEVLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Staphylococcus aureus
molecule keywords Peptide deformylase
total genus 52
structure length 184
sequence length 185
ec nomenclature ec 3.5.1.88: Peptide deformylase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01327 Pep_deformylase Polypeptide deformylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.45.10 Alpha Beta Alpha-Beta Complex Peptide Deformylase Peptide deformylase 3u7lA00
5JF4A 1XEMA 1LMEA 5JF0A 5CWXA 1ZXZA 2AIEP 1BSJA 1LQWA 2DEFA 3M6RA 5CPDA 3STRP 4NT8A 1VEYA 4E9AA 4AL3A 3PN4A 3U7MA 1Q1YA 2W3UA 4DR9A 4JE8A 3PN6A 1WS1A 5KOBA 5JF7A 1IX1A 5JF1A 1G2AA 3CMDA 5I2BA 5CVPA 2EW6A 5JEXA 5T8ZA 1VEVA 1LRYA 1ZY0A 4DR8A 3U7LA 2EW7A 1N5NA 5CXJA 5JF8A 1Y6HA 1ICJA 3E3UA 5JEZA 3OCAA 1BS5A 1LM6A 3PN5A 3K6LA 1G27A 1S17A 4WXKA 1BSZA 2KMNA 5CX0A 1V3YA 1XENA 3M6OA 3UWBA 3G5KA 4JE6A 5CWYA 4AZ4A 1SZZA 2AIAA 3UWAA 3U7NA 1DEFA 1LM4A 3U04A 3FWXA 3PN2A 2AI8A 3QU1A 4JE7A 3CPMA 2AI9A 2OS0A 3O3JA 4AL2A 2OS3A 2EW5A 2OKLA 1SV2A 1VEZA 3M6QA 1RL4A 4WXLA 2W3TA 3SVJP 5CP0A 5JF6A 3L87A 3G5PA 1DFFA 1BS4A 5CVQA 5CY7A 1LQYA 3PN3A 1BS7A 1LMHA 5CVKA 4EOXP 2AI7A 5HGWA 5JF5A 5E5DA 3G6NA 1BSKA 1XEOA 3SW8P 3U7KA 5JF3A 1ZY1A 1RQCA 1BS6A 5CY8A 2OS1A 5JF2A 1WS0A 1LRUA 3M6PA 1BS8A 5J46A 1JYMA 4E9BA 5JEYA
chains in the Genus database with same CATH superfamily
5JF4A 1XEMA 1LMEA 5JF0A 5CWXA 1ZXZA 2AIEP 1BSJA 1LQWA 2DEFA 3M6RA 5CPDA 3STRP 4NT8A 1VEYA 4E9AA 4AL3A 3PN4A 3U7MA 1Q1YA 2W3UA 4DR9A 4JE8A 3PN6A 1WS1A 5KOBA 5JF7A 1IX1A 5JF1A 1G2AA 3CMDA 5I2BA 5CVPA 2EW6A 5JEXA 5T8ZA 1VEVA 1LRYA 1ZY0A 4DR8A 3U7LA 2EW7A 1N5NA 5CXJA 5JF8A 1Y6HA 1ICJA 3E3UA 5JEZA 3OCAA 1BS5A 1LM6A 3PN5A 3K6LA 1G27A 1S17A 4WXKA 1BSZA 2KMNA 5CX0A 1V3YA 1XENA 3M6OA 3UWBA 3G5KA 4JE6A 5CWYA 4AZ4A 1SZZA 2AIAA 3UWAA 3U7NA 1DEFA 1LM4A 3U04A 3FWXA 3PN2A 2AI8A 3QU1A 4JE7A 3CPMA 2AI9A 2OS0A 3O3JA 4AL2A 2OS3A 2EW5A 2OKLA 1SV2A 1VEZA 3M6QA 1RL4A 4WXLA 2W3TA 3SVJP 5CP0A 5JF6A 3L87A 3G5PA 1DFFA 1BS4A 5CVQA 5CY7A 1LQYA 3PN3A 1BS7A 1LMHA 5CVKA 4EOXP 2AI7A 5HGWA 5JF5A 5E5DA 3G6NA 1BSKA 1XEOA 3SW8P 3U7KA 5JF3A 1ZY1A 1RQCA 1BS6A 5CY8A 2OS1A 5JF2A 1WS0A 1LRUA 3M6PA 1BS8A 5J46A 1JYMA 4E9BA 5JEYA
chains in the Genus database with same CATH topology
5JF4A 1XEMA 1LMEA 5JF0A 5CWXA 1ZXZA 2AIEP 1BSJA 1LQWA 2DEFA 3M6RA 5CPDA 3STRP 4NT8A 1VEYA 4E9AA 4AL3A 3PN4A 3U7MA 1Q1YA 2W3UA 4DR9A 4JE8A 3PN6A 1WS1A 5KOBA 5JF7A 1IX1A 5JF1A 1G2AA 3CMDA 5I2BA 5CVPA 2EW6A 5JEXA 5T8ZA 1VEVA 1LRYA 1ZY0A 4DR8A 3U7LA 2EW7A 1N5NA 5CXJA 5JF8A 1Y6HA 1ICJA 3E3UA 5JEZA 3OCAA 1BS5A 1LM6A 3PN5A 3K6LA 1G27A 1S17A 4WXKA 1BSZA 2KMNA 5CX0A 1V3YA 1XENA 3M6OA 3UWBA 3G5KA 4JE6A 5CWYA 4AZ4A 1SZZA 2AIAA 3UWAA 3U7NA 1DEFA 1LM4A 3U04A 3FWXA 3PN2A 2AI8A 3QU1A 4JE7A 3CPMA 2AI9A 2OS0A 3O3JA 4AL2A 2OS3A 2EW5A 2OKLA 1SV2A 1VEZA 3M6QA 1RL4A 4WXLA 2W3TA 3SVJP 5CP0A 5JF6A 3L87A 3G5PA 1DFFA 1BS4A 5CVQA 5CY7A 1LQYA 3PN3A 1BS7A 1LMHA 5CVKA 4EOXP 2AI7A 5HGWA 5JF5A 5E5DA 3G6NA 1BSKA 1XEOA 3SW8P 3U7KA 5JF3A 1ZY1A 1RQCA 1BS6A 5CY8A 2OS1A 5JF2A 1WS0A 1LRUA 3M6PA 1BS8A 5J46A 1JYMA 4E9BA 5JEYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JF4 A;  1XEM A;  1LME A;  5JF0 A;  5CWX A;  1ZXZ A;  2AIE P;  1BSJ A;  1LQW A;  2DEF A;  3M6R A;  5CPD A;  3STR P;  4NT8 A;  1VEY A;  4E9A A;  4AL3 A;  3PN4 A;  3U7M A;  1Q1Y A;  2W3U A;  4DR9 A;  4JE8 A;  3PN6 A;  1WS1 A;  5KOB A;  5JF7 A;  1IX1 A;  5JF1 A;  1G2A A;  3CMD A;  5I2B A;  5CVP A;  2EW6 A;  5JEX A;  5T8Z A;  1VEV A;  1LRY A;  1ZY0 A;  4DR8 A;  3U7L A;  2EW7 A;  1N5N A;  5CXJ A;  5JF8 A;  1Y6H A;  1ICJ A;  3E3U A;  5JEZ A;  3OCA A;  1BS5 A;  1LM6 A;  3PN5 A;  3K6L A;  1G27 A;  1S17 A;  4WXK A;  1BSZ A;  2KMN A;  5CX0 A;  1V3Y A;  1XEN A;  3M6O A;  3UWB A;  3G5K A;  4JE6 A;  5CWY A;  4AZ4 A;  1SZZ A;  2AIA A;  3UWA A;  3U7N A;  1DEF A;  1LM4 A;  3U04 A;  3FWX A;  3PN2 A;  2AI8 A;  3QU1 A;  4JE7 A;  3CPM A;  2AI9 A;  2OS0 A;  3O3J A;  4AL2 A;  2OS3 A;  2EW5 A;  2OKL A;  1SV2 A;  1VEZ A;  3M6Q A;  1RL4 A;  4WXL A;  2W3T A;  3SVJ P;  5CP0 A;  5JF6 A;  3L87 A;  3G5P A;  1DFF A;  1BS4 A;  5CVQ A;  5CY7 A;  1LQY A;  3PN3 A;  1BS7 A;  1LMH A;  5CVK A;  4EOX P;  2AI7 A;  5HGW A;  5JF5 A;  5E5D A;  3G6N A;  1BSK A;  1XEO A;  3SW8 P;  3U7K A;  5JF3 A;  1ZY1 A;  1RQC A;  1BS6 A;  5CY8 A;  2OS1 A;  5JF2 A;  1WS0 A;  1LRU A;  3M6P A;  1BS8 A;  5J46 A;  1JYM A;  4E9B A;  5JEY A; 
#chains in the Genus database with same CATH topology
 5JF4 A;  1XEM A;  1LME A;  5JF0 A;  5CWX A;  1ZXZ A;  2AIE P;  1BSJ A;  1LQW A;  2DEF A;  3M6R A;  5CPD A;  3STR P;  4NT8 A;  1VEY A;  4E9A A;  4AL3 A;  3PN4 A;  3U7M A;  1Q1Y A;  2W3U A;  4DR9 A;  4JE8 A;  3PN6 A;  1WS1 A;  5KOB A;  5JF7 A;  1IX1 A;  5JF1 A;  1G2A A;  3CMD A;  5I2B A;  5CVP A;  2EW6 A;  5JEX A;  5T8Z A;  1VEV A;  1LRY A;  1ZY0 A;  4DR8 A;  3U7L A;  2EW7 A;  1N5N A;  5CXJ A;  5JF8 A;  1Y6H A;  1ICJ A;  3E3U A;  5JEZ A;  3OCA A;  1BS5 A;  1LM6 A;  3PN5 A;  3K6L A;  1G27 A;  1S17 A;  4WXK A;  1BSZ A;  2KMN A;  5CX0 A;  1V3Y A;  1XEN A;  3M6O A;  3UWB A;  3G5K A;  4JE6 A;  5CWY A;  4AZ4 A;  1SZZ A;  2AIA A;  3UWA A;  3U7N A;  1DEF A;  1LM4 A;  3U04 A;  3FWX A;  3PN2 A;  2AI8 A;  3QU1 A;  4JE7 A;  3CPM A;  2AI9 A;  2OS0 A;  3O3J A;  4AL2 A;  2OS3 A;  2EW5 A;  2OKL A;  1SV2 A;  1VEZ A;  3M6Q A;  1RL4 A;  4WXL A;  2W3T A;  3SVJ P;  5CP0 A;  5JF6 A;  3L87 A;  3G5P A;  1DFF A;  1BS4 A;  5CVQ A;  5CY7 A;  1LQY A;  3PN3 A;  1BS7 A;  1LMH A;  5CVK A;  4EOX P;  2AI7 A;  5HGW A;  5JF5 A;  5E5D A;  3G6N A;  1BSK A;  1XEO A;  3SW8 P;  3U7K A;  5JF3 A;  1ZY1 A;  1RQC A;  1BS6 A;  5CY8 A;  2OS1 A;  5JF2 A;  1WS0 A;  1LRU A;  3M6P A;  1BS8 A;  5J46 A;  1JYM A;  4E9B A;  5JEY A; 
#chains in the Genus database with same CATH homology
 5JF4 A;  1XEM A;  1LME A;  5JF0 A;  5CWX A;  1ZXZ A;  2AIE P;  1BSJ A;  1LQW A;  2DEF A;  3M6R A;  5CPD A;  3STR P;  4NT8 A;  1VEY A;  4E9A A;  4AL3 A;  3PN4 A;  3U7M A;  1Q1Y A;  2W3U A;  4DR9 A;  4JE8 A;  3PN6 A;  1WS1 A;  5KOB A;  5JF7 A;  1IX1 A;  5JF1 A;  1G2A A;  3CMD A;  5I2B A;  5CVP A;  2EW6 A;  5JEX A;  5T8Z A;  1VEV A;  1LRY A;  1ZY0 A;  4DR8 A;  3U7L A;  2EW7 A;  1N5N A;  5CXJ A;  5JF8 A;  1Y6H A;  1ICJ A;  3E3U A;  5JEZ A;  3OCA A;  1BS5 A;  1LM6 A;  3PN5 A;  3K6L A;  1G27 A;  1S17 A;  4WXK A;  1BSZ A;  2KMN A;  5CX0 A;  1V3Y A;  1XEN A;  3M6O A;  3UWB A;  3G5K A;  4JE6 A;  5CWY A;  4AZ4 A;  1SZZ A;  2AIA A;  3UWA A;  3U7N A;  1DEF A;  1LM4 A;  3U04 A;  3FWX A;  3PN2 A;  2AI8 A;  3QU1 A;  4JE7 A;  3CPM A;  2AI9 A;  2OS0 A;  3O3J A;  4AL2 A;  2OS3 A;  2EW5 A;  2OKL A;  1SV2 A;  1VEZ A;  3M6Q A;  1RL4 A;  4WXL A;  2W3T A;  3SVJ P;  5CP0 A;  5JF6 A;  3L87 A;  3G5P A;  1DFF A;  1BS4 A;  5CVQ A;  5CY7 A;  1LQY A;  3PN3 A;  1BS7 A;  1LMH A;  5CVK A;  4EOX P;  2AI7 A;  5HGW A;  5JF5 A;  5E5D A;  3G6N A;  1BSK A;  1XEO A;  3SW8 P;  3U7K A;  5JF3 A;  1ZY1 A;  1RQC A;  1BS6 A;  5CY8 A;  2OS1 A;  5JF2 A;  1WS0 A;  1LRU A;  3M6P A;  1BS8 A;  5J46 A;  1JYM A;  4E9B A;  5JEY A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...