3U7MA

Crystal structures of the staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
185
structure length
184
Chain Sequence
MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKDHPLQPHTDAVEVLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Staphylococcus aureus
molecule keywords Peptide deformylase
total genus 51
structure length 184
sequence length 185
ec nomenclature ec 3.5.1.88: Peptide deformylase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01327 Pep_deformylase Polypeptide deformylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.45.10 Alpha Beta Alpha-Beta Complex Peptide Deformylase Peptide deformylase 3u7mA00
4AL2A 1BS4A 1ZXZA 3U7KA 3O3JA 3PN4A 4NT8A 3PN5A 1BS5A 1DEFA 1IX1A 5T8ZA 4DR8A 2W3UA 1V3YA 2AI7A 5JF1A 1WS0A 2W3TA 1G2AA 5E5DA 5JF6A 3OCAA 1BS7A 5CX0A 4JE8A 1G27A 5CPDA 1VEYA 2OS3A 5CXJA 3FWXA 3SVJP 3G5KA 1S17A 1LRYA 4AZ4A 1LRUA 1RL4A 5CWYA 5HGWA 5JEYA 3UWAA 4E9BA 2AI8A 2OS0A 4JE7A 4AL3A 5CVKA 2EW6A 4WXLA 5JEXA 3M6QA 5JF8A 1BS6A 4JE6A 1BSJA 1ICJA 1Q1YA 4EOXP 1VEZA 1SZZA 3U7NA 3M6PA 2OKLA 1WS1A 3PN6A 4E9AA 3QU1A 1BS8A 5JF5A 3G5PA 2OS1A 2EW7A 1DFFA 5CVPA 5CWXA 3U7MA 4DR9A 3E3UA 1BSZA 5CY8A 1VEVA 1LMHA 3PN3A 2EW5A 3M6RA 3SW8P 3UWBA 1SV2A 1LQWA 5JF0A 1JYMA 4WXKA 5JF4A 3K6LA 3M6OA 1XENA 1ZY1A 5CP0A 1N5NA 1LQYA 3PN2A 3CPMA 5CY7A 1BSKA 3CMDA 3L87A 2AI9A 5CVQA 2DEFA 5I2BA 1LM6A 3G6NA 5KOBA 1Y6HA 5JEZA 1LMEA 1XEMA 3U7LA 5JF7A 2AIAA 3STRP 1XEOA 1LM4A 2KMNA 3U04A 5J46A 1RQCA 5JF3A 2AIEP 5JF2A 1ZY0A
chains in the Genus database with same CATH superfamily
4AL2A 1BS4A 1ZXZA 3U7KA 3O3JA 3PN4A 4NT8A 3PN5A 1BS5A 1DEFA 1IX1A 5T8ZA 4DR8A 2W3UA 1V3YA 2AI7A 5JF1A 1WS0A 2W3TA 1G2AA 5E5DA 5JF6A 3OCAA 1BS7A 5CX0A 4JE8A 1G27A 5CPDA 1VEYA 2OS3A 5CXJA 3FWXA 3SVJP 3G5KA 1S17A 1LRYA 4AZ4A 1LRUA 1RL4A 5CWYA 5HGWA 5JEYA 3UWAA 4E9BA 2AI8A 2OS0A 4JE7A 4AL3A 5CVKA 2EW6A 4WXLA 5JEXA 3M6QA 5JF8A 1BS6A 4JE6A 1BSJA 1ICJA 1Q1YA 4EOXP 1VEZA 1SZZA 3U7NA 3M6PA 2OKLA 1WS1A 3PN6A 4E9AA 3QU1A 1BS8A 5JF5A 3G5PA 2OS1A 2EW7A 1DFFA 5CVPA 5CWXA 3U7MA 4DR9A 3E3UA 1BSZA 5CY8A 1VEVA 1LMHA 3PN3A 2EW5A 3M6RA 3SW8P 3UWBA 1SV2A 1LQWA 5JF0A 1JYMA 4WXKA 5JF4A 3K6LA 3M6OA 1XENA 1ZY1A 5CP0A 1N5NA 1LQYA 3PN2A 3CPMA 5CY7A 1BSKA 3CMDA 3L87A 2AI9A 5CVQA 2DEFA 5I2BA 1LM6A 3G6NA 5KOBA 1Y6HA 5JEZA 1LMEA 1XEMA 3U7LA 5JF7A 2AIAA 3STRP 1XEOA 1LM4A 2KMNA 3U04A 5J46A 1RQCA 5JF3A 2AIEP 5JF2A 1ZY0A
chains in the Genus database with same CATH topology
4AL2A 1BS4A 1ZXZA 3U7KA 3O3JA 3PN4A 4NT8A 3PN5A 1BS5A 1DEFA 1IX1A 5T8ZA 4DR8A 2W3UA 1V3YA 2AI7A 5JF1A 1WS0A 2W3TA 1G2AA 5E5DA 5JF6A 3OCAA 1BS7A 5CX0A 4JE8A 1G27A 5CPDA 1VEYA 2OS3A 5CXJA 3FWXA 3SVJP 3G5KA 1S17A 1LRYA 4AZ4A 1LRUA 1RL4A 5CWYA 5HGWA 5JEYA 3UWAA 4E9BA 2AI8A 2OS0A 4JE7A 4AL3A 5CVKA 2EW6A 4WXLA 5JEXA 3M6QA 5JF8A 1BS6A 4JE6A 1BSJA 1ICJA 1Q1YA 4EOXP 1VEZA 1SZZA 3U7NA 3M6PA 2OKLA 1WS1A 3PN6A 4E9AA 3QU1A 1BS8A 5JF5A 3G5PA 2OS1A 2EW7A 1DFFA 5CVPA 5CWXA 3U7MA 4DR9A 3E3UA 1BSZA 5CY8A 1VEVA 1LMHA 3PN3A 2EW5A 3M6RA 3SW8P 3UWBA 1SV2A 1LQWA 5JF0A 1JYMA 4WXKA 5JF4A 3K6LA 3M6OA 1XENA 1ZY1A 5CP0A 1N5NA 1LQYA 3PN2A 3CPMA 5CY7A 1BSKA 3CMDA 3L87A 2AI9A 5CVQA 2DEFA 5I2BA 1LM6A 3G6NA 5KOBA 1Y6HA 5JEZA 1LMEA 1XEMA 3U7LA 5JF7A 2AIAA 3STRP 1XEOA 1LM4A 2KMNA 3U04A 5J46A 1RQCA 5JF3A 2AIEP 5JF2A 1ZY0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AL2 A;  1BS4 A;  1ZXZ A;  3U7K A;  3O3J A;  3PN4 A;  4NT8 A;  3PN5 A;  1BS5 A;  1DEF A;  1IX1 A;  5T8Z A;  4DR8 A;  2W3U A;  1V3Y A;  2AI7 A;  5JF1 A;  1WS0 A;  2W3T A;  1G2A A;  5E5D A;  5JF6 A;  3OCA A;  1BS7 A;  5CX0 A;  4JE8 A;  1G27 A;  5CPD A;  1VEY A;  2OS3 A;  5CXJ A;  3FWX A;  3SVJ P;  3G5K A;  1S17 A;  1LRY A;  4AZ4 A;  1LRU A;  1RL4 A;  5CWY A;  5HGW A;  5JEY A;  3UWA A;  4E9B A;  2AI8 A;  2OS0 A;  4JE7 A;  4AL3 A;  5CVK A;  2EW6 A;  4WXL A;  5JEX A;  3M6Q A;  5JF8 A;  1BS6 A;  4JE6 A;  1BSJ A;  1ICJ A;  1Q1Y A;  4EOX P;  1VEZ A;  1SZZ A;  3U7N A;  3M6P A;  2OKL A;  1WS1 A;  3PN6 A;  4E9A A;  3QU1 A;  1BS8 A;  5JF5 A;  3G5P A;  2OS1 A;  2EW7 A;  1DFF A;  5CVP A;  5CWX A;  3U7M A;  4DR9 A;  3E3U A;  1BSZ A;  5CY8 A;  1VEV A;  1LMH A;  3PN3 A;  2EW5 A;  3M6R A;  3SW8 P;  3UWB A;  1SV2 A;  1LQW A;  5JF0 A;  1JYM A;  4WXK A;  5JF4 A;  3K6L A;  3M6O A;  1XEN A;  1ZY1 A;  5CP0 A;  1N5N A;  1LQY A;  3PN2 A;  3CPM A;  5CY7 A;  1BSK A;  3CMD A;  3L87 A;  2AI9 A;  5CVQ A;  2DEF A;  5I2B A;  1LM6 A;  3G6N A;  5KOB A;  1Y6H A;  5JEZ A;  1LME A;  1XEM A;  3U7L A;  5JF7 A;  2AIA A;  3STR P;  1XEO A;  1LM4 A;  2KMN A;  3U04 A;  5J46 A;  1RQC A;  5JF3 A;  2AIE P;  5JF2 A;  1ZY0 A; 
#chains in the Genus database with same CATH topology
 4AL2 A;  1BS4 A;  1ZXZ A;  3U7K A;  3O3J A;  3PN4 A;  4NT8 A;  3PN5 A;  1BS5 A;  1DEF A;  1IX1 A;  5T8Z A;  4DR8 A;  2W3U A;  1V3Y A;  2AI7 A;  5JF1 A;  1WS0 A;  2W3T A;  1G2A A;  5E5D A;  5JF6 A;  3OCA A;  1BS7 A;  5CX0 A;  4JE8 A;  1G27 A;  5CPD A;  1VEY A;  2OS3 A;  5CXJ A;  3FWX A;  3SVJ P;  3G5K A;  1S17 A;  1LRY A;  4AZ4 A;  1LRU A;  1RL4 A;  5CWY A;  5HGW A;  5JEY A;  3UWA A;  4E9B A;  2AI8 A;  2OS0 A;  4JE7 A;  4AL3 A;  5CVK A;  2EW6 A;  4WXL A;  5JEX A;  3M6Q A;  5JF8 A;  1BS6 A;  4JE6 A;  1BSJ A;  1ICJ A;  1Q1Y A;  4EOX P;  1VEZ A;  1SZZ A;  3U7N A;  3M6P A;  2OKL A;  1WS1 A;  3PN6 A;  4E9A A;  3QU1 A;  1BS8 A;  5JF5 A;  3G5P A;  2OS1 A;  2EW7 A;  1DFF A;  5CVP A;  5CWX A;  3U7M A;  4DR9 A;  3E3U A;  1BSZ A;  5CY8 A;  1VEV A;  1LMH A;  3PN3 A;  2EW5 A;  3M6R A;  3SW8 P;  3UWB A;  1SV2 A;  1LQW A;  5JF0 A;  1JYM A;  4WXK A;  5JF4 A;  3K6L A;  3M6O A;  1XEN A;  1ZY1 A;  5CP0 A;  1N5N A;  1LQY A;  3PN2 A;  3CPM A;  5CY7 A;  1BSK A;  3CMD A;  3L87 A;  2AI9 A;  5CVQ A;  2DEF A;  5I2B A;  1LM6 A;  3G6N A;  5KOB A;  1Y6H A;  5JEZ A;  1LME A;  1XEM A;  3U7L A;  5JF7 A;  2AIA A;  3STR P;  1XEO A;  1LM4 A;  2KMN A;  3U04 A;  5J46 A;  1RQC A;  5JF3 A;  2AIE P;  5JF2 A;  1ZY0 A; 
#chains in the Genus database with same CATH homology
 4AL2 A;  1BS4 A;  1ZXZ A;  3U7K A;  3O3J A;  3PN4 A;  4NT8 A;  3PN5 A;  1BS5 A;  1DEF A;  1IX1 A;  5T8Z A;  4DR8 A;  2W3U A;  1V3Y A;  2AI7 A;  5JF1 A;  1WS0 A;  2W3T A;  1G2A A;  5E5D A;  5JF6 A;  3OCA A;  1BS7 A;  5CX0 A;  4JE8 A;  1G27 A;  5CPD A;  1VEY A;  2OS3 A;  5CXJ A;  3FWX A;  3SVJ P;  3G5K A;  1S17 A;  1LRY A;  4AZ4 A;  1LRU A;  1RL4 A;  5CWY A;  5HGW A;  5JEY A;  3UWA A;  4E9B A;  2AI8 A;  2OS0 A;  4JE7 A;  4AL3 A;  5CVK A;  2EW6 A;  4WXL A;  5JEX A;  3M6Q A;  5JF8 A;  1BS6 A;  4JE6 A;  1BSJ A;  1ICJ A;  1Q1Y A;  4EOX P;  1VEZ A;  1SZZ A;  3U7N A;  3M6P A;  2OKL A;  1WS1 A;  3PN6 A;  4E9A A;  3QU1 A;  1BS8 A;  5JF5 A;  3G5P A;  2OS1 A;  2EW7 A;  1DFF A;  5CVP A;  5CWX A;  3U7M A;  4DR9 A;  3E3U A;  1BSZ A;  5CY8 A;  1VEV A;  1LMH A;  3PN3 A;  2EW5 A;  3M6R A;  3SW8 P;  3UWB A;  1SV2 A;  1LQW A;  5JF0 A;  1JYM A;  4WXK A;  5JF4 A;  3K6L A;  3M6O A;  1XEN A;  1ZY1 A;  5CP0 A;  1N5N A;  1LQY A;  3PN2 A;  3CPM A;  5CY7 A;  1BSK A;  3CMD A;  3L87 A;  2AI9 A;  5CVQ A;  2DEF A;  5I2B A;  1LM6 A;  3G6N A;  5KOB A;  1Y6H A;  5JEZ A;  1LME A;  1XEM A;  3U7L A;  5JF7 A;  2AIA A;  3STR P;  1XEO A;  1LM4 A;  2KMN A;  3U04 A;  5J46 A;  1RQC A;  5JF3 A;  2AIE P;  5JF2 A;  1ZY0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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