The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
99
|
sequence length |
353
|
structure length |
339
|
Chain Sequence |
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQLFNNTCINGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors.
pubmed doi rcsb |
| molecule keywords |
clade A/E 93TH057 HIV-1 gp120 core
|
| molecule tags |
Viral protein/inhibitor
|
| source organism |
Human immunodeficiency virus type 1
|
| total genus |
99
|
| structure length |
339
|
| sequence length |
353
|
| ec nomenclature | |
| pdb deposition date | 2012-02-03 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Beta Complex | HIV Envelope Protein Gp120; Chain G | Human immunodeficiency virus 1, Gp160, envelope glycoprotein |
#chains in the Genus database with same CATH superfamily 2I5Y G; 4YE4 G; 4S1S G; 2I60 G; 4DKP A; 4LSR G; 5FA2 A; 4DKR A; 2NXZ A; 4DVX A; 5TE4 G; 5TE6 G; 5F4L A; 4JKP G; 2NY5 G; 3SE9 G; 4RFO G; 4YDL A; 4RFN A; 4OLW G; 1G9N G; 3RJQ A; 4DKQ A; 5CD5 A; 3TGR A; 2NY3 A; 2NY7 G; 4OLX G; 5I9Q A; 3HI1 G; 4JPW G; 3SE8 G; 3TGQ A; 4OLY G; 4XNZ A; 4DVT A; 4JB9 G; 4LAJ A; 2B4C G; 3NGB A; 3TGT A; 2BF1 A; 4YDI G; 1RZJ G; 4YDK G; 4OM0 G; 2NY1 A; 1YYL G; 5KJR G; 5IGX G; 4LST G; 4YDJ G; 4LSQ G; 4OLV G; 4OLZ G; 4JDT G; 4RZ8 A; 5F96 G; 4JM2 E; 5F4U A; 4P9H G; 4OM1 G; 3TGS A; 4OLU G; 3FUS A; 4LSS G; 1GC1 G; 4R2G A; 4J6R G; 5F9W A; 1RZK G; 3TIH A; 1G9M G; 4DVW A; 4R4F A; 4DVR G; 2NY2 A; 2NY4 A; 4JZW A; 4DVS A; 4KA2 A; 2NY6 A; 4JPV G; 4I53 A; 2NY0 A; 4K0A A; 4JZZ A; 4S1Q G; 2QAD A; 4RWY A; 4DVV A; 4XNY G; 4I54 A; 4YFL E; 4XMP G; 4RX4 E; 4S1R G; 3U7Y G; 4H8W G; 5CAY G; 5TE7 G; 5T33 G; 4DKU A; 4LSV G; 5F9O G; 4R4N A; 4DKO A; 4XVT G; 3LQA G; 3IDY A; 3IDX G; 4LSP G; 1YYM G; 4DKV A; 2NXY A; 4LSU G; 3JWD A; 3JWO A; 5F4P A; 5F4R A; 4XVS G; 5FEC C; #chains in the Genus database with same CATH topology 2I5Y G; 4YE4 G; 4S1S G; 2I60 G; 4DKP A; 4LSR G; 5FA2 A; 4DKR A; 2NXZ A; 4DVX A; 5TE4 G; 5TE6 G; 5F4L A; 4JKP G; 2NY5 G; 3SE9 G; 4RFO G; 4YDL A; 4RFN A; 4OLW G; 1G9N G; 3RJQ A; 4DKQ A; 5CD5 A; 3TGR A; 2NY3 A; 2NY7 G; 4OLX G; 5I9Q A; 3HI1 G; 4JPW G; 3SE8 G; 3TGQ A; 4OLY G; 4XNZ A; 4DVT A; 4JB9 G; 4LAJ A; 2B4C G; 3NGB A; 3TGT A; 2BF1 A; 4YDI G; 1RZJ G; 4YDK G; 4OM0 G; 2NY1 A; 1YYL G; 5KJR G; 5IGX G; 4LST G; 4YDJ G; 4LSQ G; 4OLV G; 4OLZ G; 4JDT G; 4RZ8 A; 5F96 G; 4JM2 E; 5F4U A; 4P9H G; 4OM1 G; 3TGS A; 4OLU G; 3FUS A; 4LSS G; 1GC1 G; 4R2G A; 4J6R G; 5F9W A; 1RZK G; 3TIH A; 1G9M G; 4DVW A; 4R4F A; 4DVR G; 2NY2 A; 2NY4 A; 4JZW A; 4DVS A; 4KA2 A; 2NY6 A; 4JPV G; 4I53 A; 2NY0 A; 4K0A A; 4JZZ A; 4S1Q G; 2QAD A; 4RWY A; 4DVV A; 4XNY G; 4I54 A; 4YFL E; 4XMP G; 4RX4 E; 4S1R G; 3U7Y G; 4H8W G; 5CAY G; 5TE7 G; 5T33 G; 4DKU A; 4LSV G; 5F9O G; 4R4N A; 4DKO A; 4XVT G; 3LQA G; 3IDY A; 3IDX G; 4LSP G; 1YYM G; 4DKV A; 2NXY A; 4LSU G; 3JWD A; 3JWO A; 5F4P A; 5F4R A; 4XVS G; 5FEC C; #chains in the Genus database with same CATH homology 2I5Y G; 4YE4 G; 4S1S G; 2I60 G; 4DKP A; 4LSR G; 5FA2 A; 4DKR A; 2NXZ A; 4DVX A; 5TE4 G; 5TE6 G; 5F4L A; 4JKP G; 2NY5 G; 3SE9 G; 4RFO G; 4YDL A; 4RFN A; 4OLW G; 1G9N G; 3RJQ A; 4DKQ A; 5CD5 A; 3TGR A; 2NY3 A; 2NY7 G; 4OLX G; 5I9Q A; 3HI1 G; 4JPW G; 3SE8 G; 3TGQ A; 4OLY G; 4XNZ A; 4DVT A; 4JB9 G; 4LAJ A; 2B4C G; 3NGB A; 3TGT A; 2BF1 A; 4YDI G; 1RZJ G; 4YDK G; 4OM0 G; 2NY1 A; 1YYL G; 5KJR G; 5IGX G; 4LST G; 4YDJ G; 4LSQ G; 4OLV G; 4OLZ G; 4JDT G; 4RZ8 A; 5F96 G; 4JM2 E; 5F4U A; 4P9H G; 4OM1 G; 3TGS A; 4OLU G; 3FUS A; 4LSS G; 1GC1 G; 4R2G A; 4J6R G; 5F9W A; 1RZK G; 3TIH A; 1G9M G; 4DVW A; 4R4F A; 4DVR G; 2NY2 A; 2NY4 A; 4JZW A; 4DVS A; 4KA2 A; 2NY6 A; 4JPV G; 4I53 A; 2NY0 A; 4K0A A; 4JZZ A; 4S1Q G; 2QAD A; 4RWY A; 4DVV A; 4XNY G; 4I54 A; 4YFL E; 4XMP G; 4RX4 E; 4S1R G; 3U7Y G; 4H8W G; 5CAY G; 5TE7 G; 5T33 G; 4DKU A; 4LSV G; 5F9O G; 4R4N A; 4DKO A; 4XVT G; 3LQA G; 3IDY A; 3IDX G; 4LSP G; 1YYM G; 4DKV A; 2NXY A; 4LSU G; 3JWD A; 3JWO A; 5F4P A; 5F4R A; 4XVS G; 5FEC C;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
