4DKVA

Crystal structure of clade a/e 93th057 hiv-1 gp120 core in complex with nbd-10007
Total Genus 97
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
353
structure length
339
Chain Sequence
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQLFNNTCINGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 gp120 core
total genus 97
structure length 339
sequence length 353
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00516 GP120 Envelope glycoprotein GP120
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 4dkvA01
4DKQA 2NY2A 1GC1G 3LQAG 4DVXA 4S1RG 5F4LA 4DKUA 5F4RA 1RZJG 4OLYG 4RWYA 4P9HG 1G9MG 3SE9G 4DVVA 4DVWA 3NGBA 5TE6G 2NY0A 4OLVG 5CAYG 2NY1A 5TE7G 5KJRG 4OLWG 4DKPA 5CD5A 4RZ8A 4XNZA 4JZWA 3TGRA 5F4UA 4DKRA 4XNYG 5F4PA 3SE8G 4JM2E 3HI1G 4KA2A 4JDTG 4RFNA 4JKPG 2NXZA 4JB9G 4YDKG 2I60G 4S1SG 4I53A 5F9OG 5I9QA 3U7YG 4RX4E 4LAJA 4OM1G 3RJQA 1RZKG 2I5YG 5T33G 4I54A 4LSVG 4LSQG 2NY3A 2NY7G 5TE4G 4OLZG 4DKVA 4XMPG 3IDXG 4LSUG 4OLXG 4OLUG 2BF1A 5F9WA 3TGTA 4S1QG 1YYMG 4LSTG 5FA2A 3JWDA 4YDJG 3TGSA 4YDLA 4R2GA 4DVTA 4LSRG 3FUSA 3TGQA 4JPWG 2NY6A 2NXYA 4LSSG 4RFOG 4XVTG 4YFLE 4XVSG 4R4NA 3TIHA 4LSPG 2NY5G 4DKOA 2B4CG 4YE4G 5IGXG 4JZZA 4J6RG 4DVRG 5FECC 1G9NG 2QADA 4OM0G 4H8WG 4DVSA 2NY4A 3IDYA 3JWOA 4K0AA 1YYLG 4YDIG 4JPVG 5F96G 4R4FA
chains in the Genus database with same CATH superfamily
4DKQA 2NY2A 1GC1G 3LQAG 4DVXA 4S1RG 5F4LA 4DKUA 5F4RA 1RZJG 4OLYG 4RWYA 4P9HG 1G9MG 3SE9G 4DVVA 4DVWA 3NGBA 5TE6G 2NY0A 4OLVG 5CAYG 2NY1A 5TE7G 5KJRG 4OLWG 4DKPA 5CD5A 4RZ8A 4XNZA 4JZWA 3TGRA 5F4UA 4DKRA 4XNYG 5F4PA 3SE8G 4JM2E 3HI1G 4KA2A 4JDTG 4RFNA 4JKPG 2NXZA 4JB9G 4YDKG 2I60G 4S1SG 4I53A 5F9OG 5I9QA 3U7YG 4RX4E 4LAJA 4OM1G 3RJQA 1RZKG 2I5YG 5T33G 4I54A 4LSVG 4LSQG 2NY3A 2NY7G 5TE4G 4OLZG 4DKVA 4XMPG 3IDXG 4LSUG 4OLXG 4OLUG 2BF1A 5F9WA 3TGTA 4S1QG 1YYMG 4LSTG 5FA2A 3JWDA 4YDJG 3TGSA 4YDLA 4R2GA 4DVTA 4LSRG 3FUSA 3TGQA 4JPWG 2NY6A 2NXYA 4LSSG 4RFOG 4XVTG 4YFLE 4XVSG 4R4NA 3TIHA 4LSPG 2NY5G 4DKOA 2B4CG 4YE4G 5IGXG 4JZZA 4J6RG 4DVRG 5FECC 1G9NG 2QADA 4OM0G 4H8WG 4DVSA 2NY4A 3IDYA 3JWOA 4K0AA 1YYLG 4YDIG 4JPVG 5F96G 4R4FA
chains in the Genus database with same CATH topology
4DKQA 2NY2A 1GC1G 3LQAG 4DVXA 4S1RG 5F4LA 4DKUA 5F4RA 1RZJG 4OLYG 4RWYA 4P9HG 1G9MG 3SE9G 4DVVA 4DVWA 3NGBA 5TE6G 2NY0A 4OLVG 5CAYG 2NY1A 5TE7G 5KJRG 4OLWG 4DKPA 5CD5A 4RZ8A 4XNZA 4JZWA 3TGRA 5F4UA 4DKRA 4XNYG 5F4PA 3SE8G 4JM2E 3HI1G 4KA2A 4JDTG 4RFNA 4JKPG 2NXZA 4JB9G 4YDKG 2I60G 4S1SG 4I53A 5F9OG 5I9QA 3U7YG 4RX4E 4LAJA 4OM1G 3RJQA 1RZKG 2I5YG 5T33G 4I54A 4LSVG 4LSQG 2NY3A 2NY7G 5TE4G 4OLZG 4DKVA 4XMPG 3IDXG 4LSUG 4OLXG 4OLUG 2BF1A 5F9WA 3TGTA 4S1QG 1YYMG 4LSTG 5FA2A 3JWDA 4YDJG 3TGSA 4YDLA 4R2GA 4DVTA 4LSRG 3FUSA 3TGQA 4JPWG 2NY6A 2NXYA 4LSSG 4RFOG 4XVTG 4YFLE 4XVSG 4R4NA 3TIHA 4LSPG 2NY5G 4DKOA 2B4CG 4YE4G 5IGXG 4JZZA 4J6RG 4DVRG 5FECC 1G9NG 2QADA 4OM0G 4H8WG 4DVSA 2NY4A 3IDYA 3JWOA 4K0AA 1YYLG 4YDIG 4JPVG 5F96G 4R4FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DKQ A;  2NY2 A;  1GC1 G;  3LQA G;  4DVX A;  4S1R G;  5F4L A;  4DKU A;  5F4R A;  1RZJ G;  4OLY G;  4RWY A;  4P9H G;  1G9M G;  3SE9 G;  4DVV A;  4DVW A;  3NGB A;  5TE6 G;  2NY0 A;  4OLV G;  5CAY G;  2NY1 A;  5TE7 G;  5KJR G;  4OLW G;  4DKP A;  5CD5 A;  4RZ8 A;  4XNZ A;  4JZW A;  3TGR A;  5F4U A;  4DKR A;  4XNY G;  5F4P A;  3SE8 G;  4JM2 E;  3HI1 G;  4KA2 A;  4JDT G;  4RFN A;  4JKP G;  2NXZ A;  4JB9 G;  4YDK G;  2I60 G;  4S1S G;  4I53 A;  5F9O G;  5I9Q A;  3U7Y G;  4RX4 E;  4LAJ A;  4OM1 G;  3RJQ A;  1RZK G;  2I5Y G;  5T33 G;  4I54 A;  4LSV G;  4LSQ G;  2NY3 A;  2NY7 G;  5TE4 G;  4OLZ G;  4DKV A;  4XMP G;  3IDX G;  4LSU G;  4OLX G;  4OLU G;  2BF1 A;  5F9W A;  3TGT A;  4S1Q G;  1YYM G;  4LST G;  5FA2 A;  3JWD A;  4YDJ G;  3TGS A;  4YDL A;  4R2G A;  4DVT A;  4LSR G;  3FUS A;  3TGQ A;  4JPW G;  2NY6 A;  2NXY A;  4LSS G;  4RFO G;  4XVT G;  4YFL E;  4XVS G;  4R4N A;  3TIH A;  4LSP G;  2NY5 G;  4DKO A;  2B4C G;  4YE4 G;  5IGX G;  4JZZ A;  4J6R G;  4DVR G;  5FEC C;  1G9N G;  2QAD A;  4OM0 G;  4H8W G;  4DVS A;  2NY4 A;  3IDY A;  3JWO A;  4K0A A;  1YYL G;  4YDI G;  4JPV G;  5F96 G;  4R4F A; 
#chains in the Genus database with same CATH topology
 4DKQ A;  2NY2 A;  1GC1 G;  3LQA G;  4DVX A;  4S1R G;  5F4L A;  4DKU A;  5F4R A;  1RZJ G;  4OLY G;  4RWY A;  4P9H G;  1G9M G;  3SE9 G;  4DVV A;  4DVW A;  3NGB A;  5TE6 G;  2NY0 A;  4OLV G;  5CAY G;  2NY1 A;  5TE7 G;  5KJR G;  4OLW G;  4DKP A;  5CD5 A;  4RZ8 A;  4XNZ A;  4JZW A;  3TGR A;  5F4U A;  4DKR A;  4XNY G;  5F4P A;  3SE8 G;  4JM2 E;  3HI1 G;  4KA2 A;  4JDT G;  4RFN A;  4JKP G;  2NXZ A;  4JB9 G;  4YDK G;  2I60 G;  4S1S G;  4I53 A;  5F9O G;  5I9Q A;  3U7Y G;  4RX4 E;  4LAJ A;  4OM1 G;  3RJQ A;  1RZK G;  2I5Y G;  5T33 G;  4I54 A;  4LSV G;  4LSQ G;  2NY3 A;  2NY7 G;  5TE4 G;  4OLZ G;  4DKV A;  4XMP G;  3IDX G;  4LSU G;  4OLX G;  4OLU G;  2BF1 A;  5F9W A;  3TGT A;  4S1Q G;  1YYM G;  4LST G;  5FA2 A;  3JWD A;  4YDJ G;  3TGS A;  4YDL A;  4R2G A;  4DVT A;  4LSR G;  3FUS A;  3TGQ A;  4JPW G;  2NY6 A;  2NXY A;  4LSS G;  4RFO G;  4XVT G;  4YFL E;  4XVS G;  4R4N A;  3TIH A;  4LSP G;  2NY5 G;  4DKO A;  2B4C G;  4YE4 G;  5IGX G;  4JZZ A;  4J6R G;  4DVR G;  5FEC C;  1G9N G;  2QAD A;  4OM0 G;  4H8W G;  4DVS A;  2NY4 A;  3IDY A;  3JWO A;  4K0A A;  1YYL G;  4YDI G;  4JPV G;  5F96 G;  4R4F A; 
#chains in the Genus database with same CATH homology
 4DKQ A;  2NY2 A;  1GC1 G;  3LQA G;  4DVX A;  4S1R G;  5F4L A;  4DKU A;  5F4R A;  1RZJ G;  4OLY G;  4RWY A;  4P9H G;  1G9M G;  3SE9 G;  4DVV A;  4DVW A;  3NGB A;  5TE6 G;  2NY0 A;  4OLV G;  5CAY G;  2NY1 A;  5TE7 G;  5KJR G;  4OLW G;  4DKP A;  5CD5 A;  4RZ8 A;  4XNZ A;  4JZW A;  3TGR A;  5F4U A;  4DKR A;  4XNY G;  5F4P A;  3SE8 G;  4JM2 E;  3HI1 G;  4KA2 A;  4JDT G;  4RFN A;  4JKP G;  2NXZ A;  4JB9 G;  4YDK G;  2I60 G;  4S1S G;  4I53 A;  5F9O G;  5I9Q A;  3U7Y G;  4RX4 E;  4LAJ A;  4OM1 G;  3RJQ A;  1RZK G;  2I5Y G;  5T33 G;  4I54 A;  4LSV G;  4LSQ G;  2NY3 A;  2NY7 G;  5TE4 G;  4OLZ G;  4DKV A;  4XMP G;  3IDX G;  4LSU G;  4OLX G;  4OLU G;  2BF1 A;  5F9W A;  3TGT A;  4S1Q G;  1YYM G;  4LST G;  5FA2 A;  3JWD A;  4YDJ G;  3TGS A;  4YDL A;  4R2G A;  4DVT A;  4LSR G;  3FUS A;  3TGQ A;  4JPW G;  2NY6 A;  2NXY A;  4LSS G;  4RFO G;  4XVT G;  4YFL E;  4XVS G;  4R4N A;  3TIH A;  4LSP G;  2NY5 G;  4DKO A;  2B4C G;  4YE4 G;  5IGX G;  4JZZ A;  4J6R G;  4DVR G;  5FEC C;  1G9N G;  2QAD A;  4OM0 G;  4H8W G;  4DVS A;  2NY4 A;  3IDY A;  3JWO A;  4K0A A;  1YYL G;  4YDI G;  4JPV G;  5F96 G;  4R4F A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...