4DKYA

Crystal structure analysis of n terminal region containing the dimerization domain and dna binding domain of hu protein(histone like protein-dna binding) from mycobacterium tuberculosis [h37rv]
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
97
structure length
97
Chain Sequence
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors
pubmed doi rcsb
molecule keywords DNA-binding protein HU homolog
molecule tags Dna binding protein
source organism Mycobacterium tuberculosis
total genus 23
structure length 97
sequence length 97
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00216 Bac_DNA_binding Bacterial DNA-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.520.10 Few Secondary Structures Irregular HU Protein; Chain A IHF-like DNA-binding proteins 4dkyA00
1RIYA 2NP2A 4PT4A 4YEWA 2NDPA 1HUUA 1B8ZA 1P78A 2IIEA 3RHIA 4FMRA 2O97A 1EXEA 1OWGA 2O97B 1P71A 4YEYA 4QJUA 4YFHA 1OWFA 1OUZA 1OWGB 4N1VA 1OWFB 1HUEA 1OUZB 1P51A 5FBMA 1WTUA 4YFTC 5L8ZA 4DKYA 4QJNA 4YEXA 2IIFA 1IHFA 1IHFB 4YFTA 4YEWC 5EKAA 1MULA 2HT0A 2HT0B 4P3VA 4YF0A
chains in the Genus database with same CATH superfamily
1RIYA 2NP2A 4PT4A 4YEWA 2NDPA 1HUUA 1B8ZA 1P78A 2IIEA 3RHIA 4FMRA 2O97A 1EXEA 1OWGA 2O97B 1P71A 4YEYA 4QJUA 4YFHA 1OWFA 1OUZA 1OWGB 4N1VA 1OWFB 1HUEA 1OUZB 1P51A 5FBMA 1WTUA 4YFTC 5L8ZA 4DKYA 4QJNA 4YEXA 2IIFA 1IHFA 1IHFB 4YFTA 4YEWC 5EKAA 1MULA 2HT0A 2HT0B 4P3VA 4YF0A
chains in the Genus database with same CATH topology
1RIYA 2NP2A 4PT4A 4YEWA 2NDPA 1HUUA 1B8ZA 1P78A 2IIEA 3RHIA 4FMRA 2O97A 1EXEA 1OWGA 2O97B 1P71A 4YEYA 4QJUA 4YFHA 1OWFA 1OUZA 1OWGB 4N1VA 1OWFB 1HUEA 1OUZB 1P51A 5FBMA 1WTUA 4YFTC 5L8ZA 4DKYA 4QJNA 4YEXA 2IIFA 1IHFA 1IHFB 4YFTA 4YEWC 5EKAA 1MULA 2HT0A 2HT0B 4P3VA 4YF0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RIY A;  2NP2 A;  4PT4 A;  4YEW A;  2NDP A;  1HUU A;  1B8Z A;  1P78 A;  2IIE A;  3RHI A;  4FMR A;  2O97 A;  1EXE A;  1OWG A;  2O97 B;  1P71 A;  4YEY A;  4QJU A;  4YFH A;  1OWF A;  1OUZ A;  1OWG B;  4N1V A;  1OWF B;  1HUE A;  1OUZ B;  1P51 A;  5FBM A;  1WTU A;  4YFT C;  5L8Z A;  4DKY A;  4QJN A;  4YEX A;  2IIF A;  1IHF A;  1IHF B;  4YFT A;  4YEW C;  5EKA A;  1MUL A;  2HT0 A;  2HT0 B;  4P3V A;  4YF0 A; 
#chains in the Genus database with same CATH topology
 1RIY A;  2NP2 A;  4PT4 A;  4YEW A;  2NDP A;  1HUU A;  1B8Z A;  1P78 A;  2IIE A;  3RHI A;  4FMR A;  2O97 A;  1EXE A;  1OWG A;  2O97 B;  1P71 A;  4YEY A;  4QJU A;  4YFH A;  1OWF A;  1OUZ A;  1OWG B;  4N1V A;  1OWF B;  1HUE A;  1OUZ B;  1P51 A;  5FBM A;  1WTU A;  4YFT C;  5L8Z A;  4DKY A;  4QJN A;  4YEX A;  2IIF A;  1IHF A;  1IHF B;  4YFT A;  4YEW C;  5EKA A;  1MUL A;  2HT0 A;  2HT0 B;  4P3V A;  4YF0 A; 
#chains in the Genus database with same CATH homology
 1RIY A;  2NP2 A;  4PT4 A;  4YEW A;  2NDP A;  1HUU A;  1B8Z A;  1P78 A;  2IIE A;  3RHI A;  4FMR A;  2O97 A;  1EXE A;  1OWG A;  2O97 B;  1P71 A;  4YEY A;  4QJU A;  4YFH A;  1OWF A;  1OUZ A;  1OWG B;  4N1V A;  1OWF B;  1HUE A;  1OUZ B;  1P51 A;  5FBM A;  1WTU A;  4YFT C;  5L8Z A;  4DKY A;  4QJN A;  4YEX A;  2IIF A;  1IHF A;  1IHF B;  4YFT A;  4YEW C;  5EKA A;  1MUL A;  2HT0 A;  2HT0 B;  4P3V A;  4YF0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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