4G2JA

Human pde9 in complex with selective compound
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
328
structure length
328
Chain Sequence
GSHMTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
publication title Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors.
pubmed doi rcsb
molecule keywords High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9
total genus 128
structure length 328
sequence length 328
chains with identical sequence B
ec nomenclature ec 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
pdb deposition date 2012-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 4g2jA00
3SN7A 4PHWA 3SL8A 4AJFA 3UI7A 1UDTA 4P1RA 1Y2JA 1TBFA 4HTZA 3HQZA 1RO9A 3O57A 1SO2A 2QYMA 3HQWA 3ITMA 4LLJA 4Y86A 3UUOA 3K4SA 5EDIB 3ECMA 4I9ZA 3IBJA 1Y2DA 3K3EA 5EDEA 2CHMA 2OUPA 3BJCA 4Y8CA 4I15A 3SHZA 4TPMA 5EDHA 2YY2A 4LKQA 4LM3A 4NW7A 2OVYA 3DY8A 4TPPA 3SHYA 4LLPA 3WS8A 4HF4A 3DYLA 4MRWA 3HR1A 1XM4A 4G2LA 1Y2KA 4XY2A 4FCBA 3DYSA 5C2EA 4DDLA 3ECNA 2O8HA 4MRZA 2H40A 3V93A 4AJDA 5B4LA 4G2WA 1XOZA 5C29A 3SNLA 4MVHA 4KP6A 5B4KA 5C1WA 4G2JA 2H42A 1XOMA 4LM1A 4YQHA 5C28A 3IAKA 2OUQA 1PTWA 2OURA 3SL5A 4MSEA 3HMVA 2QYNA 4C1IA 5AXQA 1UDUA 3WYLA 3V9BA 3WI2A 4PHLA 3SL4A 5DH5A 1F0JA 1XP0A 3G4IA 4JIBA 5EDGA 3DYNA 3G45A 1MKDA 1SOJA 4AJGA 3TGEA 1TB5A 1Y2EA 3LY2A 1XM6A 4WCUA 1ZKNA 4FCDA 2FM5A 1Y2CA 3K3HA 1Y2HA 4MS0A 1Q9MA 1T9SA 2OUSA 3ITUA 3HQYA 3O0JA 5EDIA 3JSWA 4OEWA 3QPPA 2OUVA 1XMUB 3G4KA 1OYNA 1T9RA 5DH4A 1Y2BA 4DFFA 5I2RA 5AXPA 4YS7A 3GWTA 3FRGA 3KKTA 1XOTA 2HD1A 3N3ZA 4MSHA 4HEUA 3TVXA 4BBXA 4LM2A 1TAZA 4WN1A 1UHOA 3B2RA 4WZIA 3SL3A 2PW3A 3DYQA 4PM0A 5C2AA 2OVVA 5K9RA 3HDZA 3JSIA 3O56A 4AJMA 2Y0JA 3D3PA 3G4LA 4E90A 3G4GA 1XLZA 3SL6A 4NPVA 4QGEA 1RO6A 4Y87A 3QI3A 2FM0A 4OGBA 4D09A 2R8QA 3W5EA 4W1OA 1XLXA 4IA0A 1XOSA 2OUYA 2QYLA 4GH6A 1Z1LA 1TBBA 1TB7A 3JWRA 5C2HA 4MD6A 1XONA 3HC8A 1XM4B 4LM0A 1XMYB 4MYQA 4OEXA 3V94A 3WYKA 4LLXA 5K32A 4LM4A 4LLKA 3IADA 1XN0A 4Y2BA 1XORA 4MUWA 2OUNA 3G58A 4P0NA 3QI4A 3SNIA 4X0FA 4ZO5A 3JWQA 1ZKLA 3QPNA 3WD9A 3TGGA 3I8VA 3WS9A 3WYMA 1RKPA 2QYKA 1XOQA 3QPOA 3G3NA 5B25A 4G2YA 4NPWA 2H44A 5EDEB 1RORA 1XMUA 2OUUA 1XMYA 3SIEA 5K1IA 4MSAA 5EDGB 2WEYA 4HTXA 4MSNA 4MSCA 4D08A 3LXGA 4AELA
chains in the Genus database with same CATH superfamily
3SN7A 4PHWA 3SL8A 4AJFA 3UI7A 1UDTA 4P1RA 1Y2JA 1TBFA 4HTZA 3HQZA 1RO9A 3O57A 1SO2A 2QYMA 3HQWA 3ITMA 4LLJA 4Y86A 3UUOA 3K4SA 5EDIB 3ECMA 4I9ZA 3IBJA 1Y2DA 3K3EA 5EDEA 2CHMA 2OUPA 3BJCA 4Y8CA 4I15A 3SHZA 4TPMA 5EDHA 2YY2A 4LKQA 4LM3A 4NW7A 2OVYA 3DY8A 4TPPA 3SHYA 4LLPA 3WS8A 4HF4A 3DYLA 4MRWA 3HR1A 1XM4A 4G2LA 1Y2KA 4XY2A 4FCBA 3DYSA 5C2EA 4DDLA 3ECNA 2O8HA 4MRZA 2H40A 3V93A 4AJDA 5B4LA 4G2WA 1XOZA 5C29A 3SNLA 4MVHA 4KP6A 5B4KA 5C1WA 4G2JA 2H42A 1XOMA 4LM1A 4YQHA 5C28A 3IAKA 2OUQA 1PTWA 2OURA 3SL5A 4MSEA 3HMVA 2QYNA 4C1IA 5AXQA 1UDUA 3WYLA 3V9BA 3WI2A 4PHLA 3SL4A 5DH5A 1F0JA 1XP0A 3G4IA 4JIBA 5EDGA 3DYNA 3G45A 1MKDA 1SOJA 4AJGA 3TGEA 1TB5A 1Y2EA 3LY2A 1XM6A 4WCUA 1ZKNA 4FCDA 2FM5A 1Y2CA 3K3HA 1Y2HA 4MS0A 1Q9MA 1T9SA 2OUSA 3ITUA 3HQYA 3O0JA 5EDIA 3JSWA 4OEWA 3QPPA 2OUVA 1XMUB 3G4KA 1OYNA 1T9RA 5DH4A 1Y2BA 4DFFA 5I2RA 5AXPA 4YS7A 3GWTA 3FRGA 3KKTA 1XOTA 2HD1A 3N3ZA 4MSHA 4HEUA 3TVXA 4BBXA 4LM2A 1TAZA 4WN1A 1UHOA 3B2RA 4WZIA 3SL3A 2PW3A 3DYQA 4PM0A 5C2AA 2OVVA 5K9RA 3HDZA 3JSIA 3O56A 4AJMA 2Y0JA 3D3PA 3G4LA 4E90A 3G4GA 1XLZA 3SL6A 4NPVA 4QGEA 1RO6A 4Y87A 3QI3A 2FM0A 4OGBA 4D09A 2R8QA 3W5EA 4W1OA 1XLXA 4IA0A 1XOSA 2OUYA 2QYLA 4GH6A 1Z1LA 1TBBA 1TB7A 3JWRA 5C2HA 4MD6A 1XONA 3HC8A 1XM4B 4LM0A 1XMYB 4MYQA 4OEXA 3V94A 3WYKA 4LLXA 5K32A 4LM4A 4LLKA 3IADA 1XN0A 4Y2BA 1XORA 4MUWA 2OUNA 3G58A 4P0NA 3QI4A 3SNIA 4X0FA 4ZO5A 3JWQA 1ZKLA 3QPNA 3WD9A 3TGGA 3I8VA 3WS9A 3WYMA 1RKPA 2QYKA 1XOQA 3QPOA 3G3NA 5B25A 4G2YA 4NPWA 2H44A 5EDEB 1RORA 1XMUA 2OUUA 1XMYA 3SIEA 5K1IA 4MSAA 5EDGB 2WEYA 4HTXA 4MSNA 4MSCA 4D08A 3LXGA 4AELA
chains in the Genus database with same CATH topology
3SN7A 4PHWA 3SL8A 4AJFA 3UI7A 1UDTA 4P1RA 1Y2JA 1TBFA 4HTZA 3HQZA 1RO9A 3O57A 1SO2A 2QYMA 3HQWA 3ITMA 4LLJA 4Y86A 3UUOA 3K4SA 5EDIB 3ECMA 4I9ZA 3IBJA 1Y2DA 3K3EA 5EDEA 2CHMA 2OUPA 3BJCA 4Y8CA 4I15A 3SHZA 4TPMA 5EDHA 2YY2A 4LKQA 4LM3A 4NW7A 2OVYA 3DY8A 4TPPA 3SHYA 4LLPA 3WS8A 4HF4A 3DYLA 4MRWA 3HR1A 1XM4A 4G2LA 1Y2KA 4XY2A 4FCBA 3DYSA 5C2EA 4DDLA 3ECNA 2O8HA 4MRZA 2H40A 3V93A 4AJDA 5B4LA 4G2WA 1XOZA 5C29A 3SNLA 4MVHA 4KP6A 5B4KA 5C1WA 4G2JA 2H42A 1XOMA 4LM1A 4YQHA 5C28A 3IAKA 2OUQA 1PTWA 2OURA 3SL5A 4MSEA 3HMVA 2QYNA 4C1IA 5AXQA 1UDUA 3WYLA 3V9BA 3WI2A 4PHLA 3SL4A 5DH5A 1F0JA 1XP0A 3G4IA 4JIBA 5EDGA 3DYNA 3G45A 1MKDA 1SOJA 4AJGA 3TGEA 1TB5A 1Y2EA 3LY2A 1XM6A 4WCUA 1ZKNA 4FCDA 2FM5A 1Y2CA 3K3HA 1Y2HA 4MS0A 1Q9MA 1T9SA 2OUSA 3ITUA 3HQYA 3O0JA 5EDIA 3JSWA 4OEWA 3QPPA 2OUVA 1XMUB 3G4KA 1OYNA 1T9RA 5DH4A 1Y2BA 4DFFA 5I2RA 5AXPA 4YS7A 3GWTA 3FRGA 3KKTA 1XOTA 2HD1A 3N3ZA 4MSHA 4HEUA 3TVXA 4BBXA 4LM2A 1TAZA 4WN1A 1UHOA 3B2RA 4WZIA 3SL3A 2PW3A 3DYQA 4PM0A 5C2AA 2OVVA 5K9RA 3HDZA 3JSIA 3O56A 4AJMA 2Y0JA 3D3PA 3G4LA 4E90A 3G4GA 1XLZA 3SL6A 4NPVA 4QGEA 1RO6A 4Y87A 3QI3A 2FM0A 4OGBA 4D09A 2R8QA 3W5EA 4W1OA 1XLXA 4IA0A 1XOSA 2OUYA 2QYLA 4GH6A 1Z1LA 1TBBA 1TB7A 3JWRA 5C2HA 4MD6A 1XONA 3HC8A 1XM4B 4LM0A 1XMYB 4MYQA 4OEXA 3V94A 3WYKA 4LLXA 5K32A 4LM4A 4LLKA 3IADA 1XN0A 4Y2BA 1XORA 4MUWA 2OUNA 3G58A 4P0NA 3QI4A 3SNIA 4X0FA 4ZO5A 3JWQA 1ZKLA 3QPNA 3WD9A 3TGGA 3I8VA 3WS9A 3WYMA 1RKPA 2QYKA 1XOQA 3QPOA 3G3NA 5B25A 4G2YA 4NPWA 2H44A 5EDEB 1RORA 1XMUA 2OUUA 1XMYA 3SIEA 5K1IA 4MSAA 5EDGB 2WEYA 4HTXA 4MSNA 4MSCA 4D08A 3LXGA 4AELA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SN7 A;  4PHW A;  3SL8 A;  4AJF A;  3UI7 A;  1UDT A;  4P1R A;  1Y2J A;  1TBF A;  4HTZ A;  3HQZ A;  1RO9 A;  3O57 A;  1SO2 A;  2QYM A;  3HQW A;  3ITM A;  4LLJ A;  4Y86 A;  3UUO A;  3K4S A;  5EDI B;  3ECM A;  4I9Z A;  3IBJ A;  1Y2D A;  3K3E A;  5EDE A;  2CHM A;  2OUP A;  3BJC A;  4Y8C A;  4I15 A;  3SHZ A;  4TPM A;  5EDH A;  2YY2 A;  4LKQ A;  4LM3 A;  4NW7 A;  2OVY A;  3DY8 A;  4TPP A;  3SHY A;  4LLP A;  3WS8 A;  4HF4 A;  3DYL A;  4MRW A;  3HR1 A;  1XM4 A;  4G2L A;  1Y2K A;  4XY2 A;  4FCB A;  3DYS A;  5C2E A;  4DDL A;  3ECN A;  2O8H A;  4MRZ A;  2H40 A;  3V93 A;  4AJD A;  5B4L A;  4G2W A;  1XOZ A;  5C29 A;  3SNL A;  4MVH A;  4KP6 A;  5B4K A;  5C1W A;  4G2J A;  2H42 A;  1XOM A;  4LM1 A;  4YQH A;  5C28 A;  3IAK A;  2OUQ A;  1PTW A;  2OUR A;  3SL5 A;  4MSE A;  3HMV A;  2QYN A;  4C1I A;  5AXQ A;  1UDU A;  3WYL A;  3V9B A;  3WI2 A;  4PHL A;  3SL4 A;  5DH5 A;  1F0J A;  1XP0 A;  3G4I A;  4JIB A;  5EDG A;  3DYN A;  3G45 A;  1MKD A;  1SOJ A;  4AJG A;  3TGE A;  1TB5 A;  1Y2E A;  3LY2 A;  1XM6 A;  4WCU A;  1ZKN A;  4FCD A;  2FM5 A;  1Y2C A;  3K3H A;  1Y2H A;  4MS0 A;  1Q9M A;  1T9S A;  2OUS A;  3ITU A;  3HQY A;  3O0J A;  5EDI A;  3JSW A;  4OEW A;  3QPP A;  2OUV A;  1XMU B;  3G4K A;  1OYN A;  1T9R A;  5DH4 A;  1Y2B A;  4DFF A;  5I2R A;  5AXP A;  4YS7 A;  3GWT A;  3FRG A;  3KKT A;  1XOT A;  2HD1 A;  3N3Z A;  4MSH A;  4HEU A;  3TVX A;  4BBX A;  4LM2 A;  1TAZ A;  4WN1 A;  1UHO A;  3B2R A;  4WZI A;  3SL3 A;  2PW3 A;  3DYQ A;  4PM0 A;  5C2A A;  2OVV A;  5K9R A;  3HDZ A;  3JSI A;  3O56 A;  4AJM A;  2Y0J A;  3D3P A;  3G4L A;  4E90 A;  3G4G A;  1XLZ A;  3SL6 A;  4NPV A;  4QGE A;  1RO6 A;  4Y87 A;  3QI3 A;  2FM0 A;  4OGB A;  4D09 A;  2R8Q A;  3W5E A;  4W1O A;  1XLX A;  4IA0 A;  1XOS A;  2OUY A;  2QYL A;  4GH6 A;  1Z1L A;  1TBB A;  1TB7 A;  3JWR A;  5C2H A;  4MD6 A;  1XON A;  3HC8 A;  1XM4 B;  4LM0 A;  1XMY B;  4MYQ A;  4OEX A;  3V94 A;  3WYK A;  4LLX A;  5K32 A;  4LM4 A;  4LLK A;  3IAD A;  1XN0 A;  4Y2B A;  1XOR A;  4MUW A;  2OUN A;  3G58 A;  4P0N A;  3QI4 A;  3SNI A;  4X0F A;  4ZO5 A;  3JWQ A;  1ZKL A;  3QPN A;  3WD9 A;  3TGG A;  3I8V A;  3WS9 A;  3WYM A;  1RKP A;  2QYK A;  1XOQ A;  3QPO A;  3G3N A;  5B25 A;  4G2Y A;  4NPW A;  2H44 A;  5EDE B;  1ROR A;  1XMU A;  2OUU A;  1XMY A;  3SIE A;  5K1I A;  4MSA A;  5EDG B;  2WEY A;  4HTX A;  4MSN A;  4MSC A;  4D08 A;  3LXG A;  4AEL A; 
#chains in the Genus database with same CATH topology
 3SN7 A;  4PHW A;  3SL8 A;  4AJF A;  3UI7 A;  1UDT A;  4P1R A;  1Y2J A;  1TBF A;  4HTZ A;  3HQZ A;  1RO9 A;  3O57 A;  1SO2 A;  2QYM A;  3HQW A;  3ITM A;  4LLJ A;  4Y86 A;  3UUO A;  3K4S A;  5EDI B;  3ECM A;  4I9Z A;  3IBJ A;  1Y2D A;  3K3E A;  5EDE A;  2CHM A;  2OUP A;  3BJC A;  4Y8C A;  4I15 A;  3SHZ A;  4TPM A;  5EDH A;  2YY2 A;  4LKQ A;  4LM3 A;  4NW7 A;  2OVY A;  3DY8 A;  4TPP A;  3SHY A;  4LLP A;  3WS8 A;  4HF4 A;  3DYL A;  4MRW A;  3HR1 A;  1XM4 A;  4G2L A;  1Y2K A;  4XY2 A;  4FCB A;  3DYS A;  5C2E A;  4DDL A;  3ECN A;  2O8H A;  4MRZ A;  2H40 A;  3V93 A;  4AJD A;  5B4L A;  4G2W A;  1XOZ A;  5C29 A;  3SNL A;  4MVH A;  4KP6 A;  5B4K A;  5C1W A;  4G2J A;  2H42 A;  1XOM A;  4LM1 A;  4YQH A;  5C28 A;  3IAK A;  2OUQ A;  1PTW A;  2OUR A;  3SL5 A;  4MSE A;  3HMV A;  2QYN A;  4C1I A;  5AXQ A;  1UDU A;  3WYL A;  3V9B A;  3WI2 A;  4PHL A;  3SL4 A;  5DH5 A;  1F0J A;  1XP0 A;  3G4I A;  4JIB A;  5EDG A;  3DYN A;  3G45 A;  1MKD A;  1SOJ A;  4AJG A;  3TGE A;  1TB5 A;  1Y2E A;  3LY2 A;  1XM6 A;  4WCU A;  1ZKN A;  4FCD A;  2FM5 A;  1Y2C A;  3K3H A;  1Y2H A;  4MS0 A;  1Q9M A;  1T9S A;  2OUS A;  3ITU A;  3HQY A;  3O0J A;  5EDI A;  3JSW A;  4OEW A;  3QPP A;  2OUV A;  1XMU B;  3G4K A;  1OYN A;  1T9R A;  5DH4 A;  1Y2B A;  4DFF A;  5I2R A;  5AXP A;  4YS7 A;  3GWT A;  3FRG A;  3KKT A;  1XOT A;  2HD1 A;  3N3Z A;  4MSH A;  4HEU A;  3TVX A;  4BBX A;  4LM2 A;  1TAZ A;  4WN1 A;  1UHO A;  3B2R A;  4WZI A;  3SL3 A;  2PW3 A;  3DYQ A;  4PM0 A;  5C2A A;  2OVV A;  5K9R A;  3HDZ A;  3JSI A;  3O56 A;  4AJM A;  2Y0J A;  3D3P A;  3G4L A;  4E90 A;  3G4G A;  1XLZ A;  3SL6 A;  4NPV A;  4QGE A;  1RO6 A;  4Y87 A;  3QI3 A;  2FM0 A;  4OGB A;  4D09 A;  2R8Q A;  3W5E A;  4W1O A;  1XLX A;  4IA0 A;  1XOS A;  2OUY A;  2QYL A;  4GH6 A;  1Z1L A;  1TBB A;  1TB7 A;  3JWR A;  5C2H A;  4MD6 A;  1XON A;  3HC8 A;  1XM4 B;  4LM0 A;  1XMY B;  4MYQ A;  4OEX A;  3V94 A;  3WYK A;  4LLX A;  5K32 A;  4LM4 A;  4LLK A;  3IAD A;  1XN0 A;  4Y2B A;  1XOR A;  4MUW A;  2OUN A;  3G58 A;  4P0N A;  3QI4 A;  3SNI A;  4X0F A;  4ZO5 A;  3JWQ A;  1ZKL A;  3QPN A;  3WD9 A;  3TGG A;  3I8V A;  3WS9 A;  3WYM A;  1RKP A;  2QYK A;  1XOQ A;  3QPO A;  3G3N A;  5B25 A;  4G2Y A;  4NPW A;  2H44 A;  5EDE B;  1ROR A;  1XMU A;  2OUU A;  1XMY A;  3SIE A;  5K1I A;  4MSA A;  5EDG B;  2WEY A;  4HTX A;  4MSN A;  4MSC A;  4D08 A;  3LXG A;  4AEL A; 
#chains in the Genus database with same CATH homology
 3SN7 A;  4PHW A;  3SL8 A;  4AJF A;  3UI7 A;  1UDT A;  4P1R A;  1Y2J A;  1TBF A;  4HTZ A;  3HQZ A;  1RO9 A;  3O57 A;  1SO2 A;  2QYM A;  3HQW A;  3ITM A;  4LLJ A;  4Y86 A;  3UUO A;  3K4S A;  5EDI B;  3ECM A;  4I9Z A;  3IBJ A;  1Y2D A;  3K3E A;  5EDE A;  2CHM A;  2OUP A;  3BJC A;  4Y8C A;  4I15 A;  3SHZ A;  4TPM A;  5EDH A;  2YY2 A;  4LKQ A;  4LM3 A;  4NW7 A;  2OVY A;  3DY8 A;  4TPP A;  3SHY A;  4LLP A;  3WS8 A;  4HF4 A;  3DYL A;  4MRW A;  3HR1 A;  1XM4 A;  4G2L A;  1Y2K A;  4XY2 A;  4FCB A;  3DYS A;  5C2E A;  4DDL A;  3ECN A;  2O8H A;  4MRZ A;  2H40 A;  3V93 A;  4AJD A;  5B4L A;  4G2W A;  1XOZ A;  5C29 A;  3SNL A;  4MVH A;  4KP6 A;  5B4K A;  5C1W A;  4G2J A;  2H42 A;  1XOM A;  4LM1 A;  4YQH A;  5C28 A;  3IAK A;  2OUQ A;  1PTW A;  2OUR A;  3SL5 A;  4MSE A;  3HMV A;  2QYN A;  4C1I A;  5AXQ A;  1UDU A;  3WYL A;  3V9B A;  3WI2 A;  4PHL A;  3SL4 A;  5DH5 A;  1F0J A;  1XP0 A;  3G4I A;  4JIB A;  5EDG A;  3DYN A;  3G45 A;  1MKD A;  1SOJ A;  4AJG A;  3TGE A;  1TB5 A;  1Y2E A;  3LY2 A;  1XM6 A;  4WCU A;  1ZKN A;  4FCD A;  2FM5 A;  1Y2C A;  3K3H A;  1Y2H A;  4MS0 A;  1Q9M A;  1T9S A;  2OUS A;  3ITU A;  3HQY A;  3O0J A;  5EDI A;  3JSW A;  4OEW A;  3QPP A;  2OUV A;  1XMU B;  3G4K A;  1OYN A;  1T9R A;  5DH4 A;  1Y2B A;  4DFF A;  5I2R A;  5AXP A;  4YS7 A;  3GWT A;  3FRG A;  3KKT A;  1XOT A;  2HD1 A;  3N3Z A;  4MSH A;  4HEU A;  3TVX A;  4BBX A;  4LM2 A;  1TAZ A;  4WN1 A;  1UHO A;  3B2R A;  4WZI A;  3SL3 A;  2PW3 A;  3DYQ A;  4PM0 A;  5C2A A;  2OVV A;  5K9R A;  3HDZ A;  3JSI A;  3O56 A;  4AJM A;  2Y0J A;  3D3P A;  3G4L A;  4E90 A;  3G4G A;  1XLZ A;  3SL6 A;  4NPV A;  4QGE A;  1RO6 A;  4Y87 A;  3QI3 A;  2FM0 A;  4OGB A;  4D09 A;  2R8Q A;  3W5E A;  4W1O A;  1XLX A;  4IA0 A;  1XOS A;  2OUY A;  2QYL A;  4GH6 A;  1Z1L A;  1TBB A;  1TB7 A;  3JWR A;  5C2H A;  4MD6 A;  1XON A;  3HC8 A;  1XM4 B;  4LM0 A;  1XMY B;  4MYQ A;  4OEX A;  3V94 A;  3WYK A;  4LLX A;  5K32 A;  4LM4 A;  4LLK A;  3IAD A;  1XN0 A;  4Y2B A;  1XOR A;  4MUW A;  2OUN A;  3G58 A;  4P0N A;  3QI4 A;  3SNI A;  4X0F A;  4ZO5 A;  3JWQ A;  1ZKL A;  3QPN A;  3WD9 A;  3TGG A;  3I8V A;  3WS9 A;  3WYM A;  1RKP A;  2QYK A;  1XOQ A;  3QPO A;  3G3N A;  5B25 A;  4G2Y A;  4NPW A;  2H44 A;  5EDE B;  1ROR A;  1XMU A;  2OUU A;  1XMY A;  3SIE A;  5K1I A;  4MSA A;  5EDG B;  2WEY A;  4HTX A;  4MSN A;  4MSC A;  4D08 A;  3LXG A;  4AEL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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