4GK6A

X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from mycobacterium abscessus
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
136
structure length
136
Chain Sequence
GSMLAIVRLDRELPLPSRAHADDAGVDLYSAEDVVIEPGRRTLVGTGIAVAIPSGMVGLVHPRSGLAARVGLSIVNSPGTIDAGYRGEVKVNLINLDSEVPIVIARGDRIAQLLVQQVELPELVEVDSFDEAGLAV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium abscessus
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 15
structure length 136
sequence length 136
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2012-08-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 4gk6A00
1RNJA 1F7NA 2Y8CA 3T6YA 4LHRA 3C2TA 2YZJA 3T64A 3ZF5A 3TPYA 3LQWA 3I93A 4B0HA 3GF0A 5F9KA 3SO2A 3TP1A 3TQ4A 3TQZA 2XCEA 3ZF3A 4OOPA 2R9QA 3TTAA 1SM8A 1Q5UX 1PKHA 1SMCA 4APZ1 2OL1A 3TS6A 2HRMA 1DUTA 2J4QA 2WE2A 5CCTA 5CCOA 2OKBA 3ECYA 4AO5A 3P48A 1XS1A 3TPWA 1EUWA 1SEHA 2XCDA 1DUPA 4A6AA 4GCYA 1SLHA 1MQ7A 2D4LA 2ZDCA 2BAZA 2XY3A 1VYQA 1SYLA 2J4HA 3HZAA 3H6XA 1OGHA 3F4FA 1SIXA 3MDXA 1DUNA 4AOZA 3ZF6A 2WE3A 1SJNA 2OL0A 3TQ3A 3TPSA 4GV8A 3CA9A 3ZF0A 2QXXA 3ZF4A 5EDDA 1Q5HA 1XS4A 3H6DA 2BT1A 1F7PA 4XJCA 2PY4A 3TSLA 2BSYA 3TQ5A 2WE0A 3TRNA 3ARAA 4WRKA 1DUDA 3EHWA 4DHKA 5ECTA 2QLPA 2XX6A 2D4MA 2Y1TA 1EU5A 3MBQA 2HQUA 1F7RA 2HXBA 2OKDA 2WE1A 3ZF2A 1PKKA 1F7KA 3ZF1A 3TPNA 3ARNA 3C3IA 2D4NA 1SNFA 4AOOA 2PC5A 2V9XA 1RN8A 3TRLA 3LOJA 3T60A 2OKEA 1XS6A 1PKJA 1F7OA 3HHQA 4GK6A 2HR6A 1DUCA 4OOQA 3T70A 3KM3A 1F7QA 1F7DA 2HXDA 3ZEZA
chains in the Genus database with same CATH superfamily
1RNJA 1F7NA 2Y8CA 3T6YA 4LHRA 3C2TA 2YZJA 3T64A 3ZF5A 3TPYA 3LQWA 3I93A 4B0HA 3GF0A 5F9KA 3SO2A 3TP1A 3TQ4A 3TQZA 2XCEA 3ZF3A 4OOPA 2R9QA 3TTAA 1SM8A 1Q5UX 1PKHA 1SMCA 4APZ1 2OL1A 3TS6A 2HRMA 1DUTA 2J4QA 2WE2A 5CCTA 5CCOA 2OKBA 3ECYA 4AO5A 3P48A 1XS1A 3TPWA 1EUWA 1SEHA 2XCDA 1DUPA 4A6AA 4GCYA 1SLHA 1MQ7A 2D4LA 2ZDCA 2BAZA 2XY3A 1VYQA 1SYLA 2J4HA 3HZAA 3H6XA 1OGHA 3F4FA 1SIXA 3MDXA 1DUNA 4AOZA 3ZF6A 2WE3A 1SJNA 2OL0A 3TQ3A 3TPSA 4GV8A 3CA9A 3ZF0A 2QXXA 3ZF4A 5EDDA 1Q5HA 1XS4A 3H6DA 2BT1A 1F7PA 4XJCA 2PY4A 3TSLA 2BSYA 3TQ5A 2WE0A 3TRNA 3ARAA 4WRKA 1DUDA 3EHWA 4DHKA 5ECTA 2QLPA 2XX6A 2D4MA 2Y1TA 1EU5A 3MBQA 2HQUA 1F7RA 2HXBA 2OKDA 2WE1A 3ZF2A 1PKKA 1F7KA 3ZF1A 3TPNA 3ARNA 3C3IA 2D4NA 1SNFA 4AOOA 2PC5A 2V9XA 1RN8A 3TRLA 3LOJA 3T60A 2OKEA 1XS6A 1TULA 1PKJA 1F7OA 3HHQA 4GK6A 2HR6A 1DUCA 4OOQA 3T70A 3KM3A 1F7QA 1F7DA 2HXDA 3ZEZA
chains in the Genus database with same CATH topology
1RNJA 1F7NA 2Y8CA 3T6YA 4LHRA 3C2TA 2YZJA 3T64A 3ZF5A 3TPYA 3LQWA 3I93A 4B0HA 3GF0A 5F9KA 3SO2A 3TP1A 3TQ4A 3TQZA 2XCEA 3ZF3A 4OOPA 2R9QA 3TTAA 1SM8A 1Q5UX 1PKHA 1SMCA 4APZ1 2OL1A 3TS6A 2HRMA 1DUTA 2J4QA 2WE2A 5CCTA 5CCOA 2OKBA 3ECYA 4AO5A 3P48A 1XS1A 3TPWA 1EUWA 1SEHA 2XCDA 1DUPA 4A6AA 4GCYA 1SLHA 1MQ7A 2D4LA 2ZDCA 2BAZA 2XY3A 1VYQA 1SYLA 2J4HA 3HZAA 3H6XA 1OGHA 3F4FA 1SIXA 3MDXA 1DUNA 4AOZA 3ZF6A 2WE3A 1SJNA 2OL0A 3TQ3A 3TPSA 4GV8A 3CA9A 3ZF0A 2QXXA 3ZF4A 5EDDA 1Q5HA 1XS4A 3H6DA 2BT1A 1F7PA 4XJCA 2PY4A 3TSLA 2BSYA 3TQ5A 2WE0A 3TRNA 3ARAA 4WRKA 1DUDA 3EHWA 4DHKA 5ECTA 2QLPA 2XX6A 2D4MA 2Y1TA 1EU5A 3MBQA 2HQUA 1F7RA 2HXBA 2OKDA 2WE1A 3ZF2A 1PKKA 1F7KA 3ZF1A 3TPNA 3ARNA 3C3IA 2D4NA 1SNFA 4AOOA 2PC5A 2V9XA 1RN8A 3TRLA 3LOJA 3T60A 2OKEA 1XS6A 1PKJA 1F7OA 3HHQA 4GK6A 2HR6A 1DUCA 4OOQA 3T70A 3KM3A 1F7QA 1F7DA 2HXDA 3ZEZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RNJ A;  1F7N A;  2Y8C A;  3T6Y A;  4LHR A;  3C2T A;  2YZJ A;  3T64 A;  3ZF5 A;  3TPY A;  3LQW A;  3I93 A;  4B0H A;  3GF0 A;  5F9K A;  3SO2 A;  3TP1 A;  3TQ4 A;  3TQZ A;  2XCE A;  3ZF3 A;  4OOP A;  2R9Q A;  3TTA A;  1SM8 A;  1Q5U X;  1PKH A;  1SMC A;  4APZ 1;  2OL1 A;  3TS6 A;  2HRM A;  1DUT A;  2J4Q A;  2WE2 A;  5CCT A;  5CCO A;  2OKB A;  3ECY A;  4AO5 A;  3P48 A;  1XS1 A;  3TPW A;  1EUW A;  1SEH A;  2XCD A;  1DUP A;  4A6A A;  4GCY A;  1SLH A;  1MQ7 A;  2D4L A;  2ZDC A;  2BAZ A;  2XY3 A;  1VYQ A;  1SYL A;  2J4H A;  3HZA A;  3H6X A;  1OGH A;  3F4F A;  1SIX A;  3MDX A;  1DUN A;  4AOZ A;  3ZF6 A;  2WE3 A;  1SJN A;  2OL0 A;  3TQ3 A;  3TPS A;  4GV8 A;  3CA9 A;  3ZF0 A;  2QXX A;  3ZF4 A;  5EDD A;  1Q5H A;  1XS4 A;  3H6D A;  2BT1 A;  1F7P A;  4XJC A;  2PY4 A;  3TSL A;  2BSY A;  3TQ5 A;  2WE0 A;  3TRN A;  3ARA A;  4WRK A;  1DUD A;  3EHW A;  4DHK A;  5ECT A;  2QLP A;  2XX6 A;  2D4M A;  2Y1T A;  1EU5 A;  3MBQ A;  2HQU A;  1F7R A;  2HXB A;  2OKD A;  2WE1 A;  3ZF2 A;  1PKK A;  1F7K A;  3ZF1 A;  3TPN A;  3ARN A;  3C3I A;  2D4N A;  1SNF A;  4AOO A;  2PC5 A;  2V9X A;  1RN8 A;  3TRL A;  3LOJ A;  3T60 A;  2OKE A;  1XS6 A;  1PKJ A;  1F7O A;  3HHQ A;  4GK6 A;  2HR6 A;  1DUC A;  4OOQ A;  3T70 A;  3KM3 A;  1F7Q A;  1F7D A;  2HXD A;  3ZEZ A; 
#chains in the Genus database with same CATH topology
 1RNJ A;  1F7N A;  2Y8C A;  3T6Y A;  4LHR A;  3C2T A;  2YZJ A;  3T64 A;  3ZF5 A;  3TPY A;  3LQW A;  3I93 A;  4B0H A;  3GF0 A;  5F9K A;  3SO2 A;  3TP1 A;  3TQ4 A;  3TQZ A;  2XCE A;  3ZF3 A;  4OOP A;  2R9Q A;  3TTA A;  1SM8 A;  1Q5U X;  1PKH A;  1SMC A;  4APZ 1;  2OL1 A;  3TS6 A;  2HRM A;  1DUT A;  2J4Q A;  2WE2 A;  5CCT A;  5CCO A;  2OKB A;  3ECY A;  4AO5 A;  3P48 A;  1XS1 A;  3TPW A;  1EUW A;  1SEH A;  2XCD A;  1DUP A;  4A6A A;  4GCY A;  1SLH A;  1MQ7 A;  2D4L A;  2ZDC A;  2BAZ A;  2XY3 A;  1VYQ A;  1SYL A;  2J4H A;  3HZA A;  3H6X A;  1OGH A;  3F4F A;  1SIX A;  3MDX A;  1DUN A;  4AOZ A;  3ZF6 A;  2WE3 A;  1SJN A;  2OL0 A;  3TQ3 A;  3TPS A;  4GV8 A;  3CA9 A;  3ZF0 A;  2QXX A;  3ZF4 A;  5EDD A;  1Q5H A;  1XS4 A;  3H6D A;  2BT1 A;  1F7P A;  4XJC A;  2PY4 A;  3TSL A;  2BSY A;  3TQ5 A;  2WE0 A;  3TRN A;  3ARA A;  4WRK A;  1DUD A;  3EHW A;  4DHK A;  5ECT A;  2QLP A;  2XX6 A;  2D4M A;  2Y1T A;  1EU5 A;  3MBQ A;  2HQU A;  1F7R A;  2HXB A;  2OKD A;  2WE1 A;  3ZF2 A;  1PKK A;  1F7K A;  3ZF1 A;  3TPN A;  3ARN A;  3C3I A;  2D4N A;  1SNF A;  4AOO A;  2PC5 A;  2V9X A;  1RN8 A;  3TRL A;  3LOJ A;  3T60 A;  2OKE A;  1XS6 A;  1TUL A;  1PKJ A;  1F7O A;  3HHQ A;  4GK6 A;  2HR6 A;  1DUC A;  4OOQ A;  3T70 A;  3KM3 A;  1F7Q A;  1F7D A;  2HXD A;  3ZEZ A; 
#chains in the Genus database with same CATH homology
 1RNJ A;  1F7N A;  2Y8C A;  3T6Y A;  4LHR A;  3C2T A;  2YZJ A;  3T64 A;  3ZF5 A;  3TPY A;  3LQW A;  3I93 A;  4B0H A;  3GF0 A;  5F9K A;  3SO2 A;  3TP1 A;  3TQ4 A;  3TQZ A;  2XCE A;  3ZF3 A;  4OOP A;  2R9Q A;  3TTA A;  1SM8 A;  1Q5U X;  1PKH A;  1SMC A;  4APZ 1;  2OL1 A;  3TS6 A;  2HRM A;  1DUT A;  2J4Q A;  2WE2 A;  5CCT A;  5CCO A;  2OKB A;  3ECY A;  4AO5 A;  3P48 A;  1XS1 A;  3TPW A;  1EUW A;  1SEH A;  2XCD A;  1DUP A;  4A6A A;  4GCY A;  1SLH A;  1MQ7 A;  2D4L A;  2ZDC A;  2BAZ A;  2XY3 A;  1VYQ A;  1SYL A;  2J4H A;  3HZA A;  3H6X A;  1OGH A;  3F4F A;  1SIX A;  3MDX A;  1DUN A;  4AOZ A;  3ZF6 A;  2WE3 A;  1SJN A;  2OL0 A;  3TQ3 A;  3TPS A;  4GV8 A;  3CA9 A;  3ZF0 A;  2QXX A;  3ZF4 A;  5EDD A;  1Q5H A;  1XS4 A;  3H6D A;  2BT1 A;  1F7P A;  4XJC A;  2PY4 A;  3TSL A;  2BSY A;  3TQ5 A;  2WE0 A;  3TRN A;  3ARA A;  4WRK A;  1DUD A;  3EHW A;  4DHK A;  5ECT A;  2QLP A;  2XX6 A;  2D4M A;  2Y1T A;  1EU5 A;  3MBQ A;  2HQU A;  1F7R A;  2HXB A;  2OKD A;  2WE1 A;  3ZF2 A;  1PKK A;  1F7K A;  3ZF1 A;  3TPN A;  3ARN A;  3C3I A;  2D4N A;  1SNF A;  4AOO A;  2PC5 A;  2V9X A;  1RN8 A;  3TRL A;  3LOJ A;  3T60 A;  2OKE A;  1XS6 A;  1PKJ A;  1F7O A;  3HHQ A;  4GK6 A;  2HR6 A;  1DUC A;  4OOQ A;  3T70 A;  3KM3 A;  1F7Q A;  1F7D A;  2HXD A;  3ZEZ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...