4H2O | Genus

Total Genus 76

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	76
sequence length	223
structure length	206
Chain Sequence	GCRHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSALMELFVWALDSEVKSLHRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEKLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 206 atoms

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206 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Antibacterial drug leads targeting isoprenoid biosynthesis. pubmed doi rcsb
molecule keywords	Undecaprenyl pyrophosphate synthase
molecule tags	Transferase/transferase inhibitor
source organism	Escherichia coli
total genus	76
structure length	206
sequence length	223
chains with identical sequence	B
ec nomenclature	ec 2.5.1.31: Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-
pdb deposition date	2012-09-13

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01255	Prenyltransf	Putative undecaprenyl diphosphate synthase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1180.10	Alpha Beta	3-Layer(aba) Sandwich	Undecaprenyl pyrophosphate synthetase	Decaprenyl diphosphate synthase-like	4h2oA00

1UEHA 2VG1A 5HC8A 5CQJA 5HXQA 4CMXA 1X06A 4Q9MA 3WQMA 3WYIA 1X07A 5KH2A 3SGVA 3SH0A 4ONCA 4CMVA 4Q9OA 3TH8A 2E9DA 2VFWA 1F75A 1X08A 5KH4A 4H2JA 2D2RA 4H38A 5HXTA 5HXNA 4H8EA 2VG2A 4H2OA 2VG4A 3UGSA 2E9AA 5HC7A 2E98A 2DTNA 4H2MA 4H3AA 3WQKA 4KT8A 1X09A 3WYJA 4CMWA 5KH5A 2VG3A 3QASA 5HC6A 3SGTA 1JP3A 4H3CA 2E99A 4U82A 1V7UA 3WQNA 5HXPA 2E9CA 3WQLA 2VG0A 5CQBA 5HXOA 3SGXA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1UEH A;  2VG1 A;  5HC8 A;  5CQJ A;  5HXQ A;  4CMX A;  1X06 A;  4Q9M A;  3WQM A;  3WYI A;  1X07 A;  5KH2 A;  3SGV A;  3SH0 A;  4ONC A;  4CMV A;  4Q9O A;  3TH8 A;  2E9D A;  2VFW A;  1F75 A;  1X08 A;  5KH4 A;  4H2J A;  2D2R A;  4H38 A;  5HXT A;  5HXN A;  4H8E A;  2VG2 A;  4H2O A;  2VG4 A;  3UGS A;  2E9A A;  5HC7 A;  2E98 A;  2DTN A;  4H2M A;  4H3A A;  3WQK A;  4KT8 A;  1X09 A;  3WYJ A;  4CMW A;  5KH5 A;  2VG3 A;  3QAS A;  5HC6 A;  3SGT A;  1JP3 A;  4H3C A;  2E99 A;  4U82 A;  1V7U A;  3WQN A;  5HXP A;  2E9C A;  3WQL A;  2VG0 A;  5CQB A;  5HXO A;  3SGX A; 
#chains in the Genus database with same CATH topology
 1UEH A;  2VG1 A;  5HC8 A;  5CQJ A;  5HXQ A;  4CMX A;  1X06 A;  4Q9M A;  3WQM A;  3WYI A;  1X07 A;  5KH2 A;  3SGV A;  3SH0 A;  4ONC A;  4CMV A;  4Q9O A;  3TH8 A;  2E9D A;  2VFW A;  1F75 A;  1X08 A;  5KH4 A;  4H2J A;  2D2R A;  4H38 A;  5HXT A;  5HXN A;  4H8E A;  2VG2 A;  4H2O A;  2VG4 A;  3UGS A;  2E9A A;  5HC7 A;  2E98 A;  2DTN A;  4H2M A;  4H3A A;  3WQK A;  4KT8 A;  1X09 A;  3WYJ A;  4CMW A;  5KH5 A;  2VG3 A;  3QAS A;  5HC6 A;  3SGT A;  1JP3 A;  4H3C A;  2E99 A;  4U82 A;  1V7U A;  3WQN A;  5HXP A;  2E9C A;  3WQL A;  2VG0 A;  5CQB A;  5HXO A;  3SGX A; 
#chains in the Genus database with same CATH homology
 1UEH A;  2VG1 A;  5HC8 A;  5CQJ A;  5HXQ A;  4CMX A;  1X06 A;  4Q9M A;  3WQM A;  3WYI A;  1X07 A;  5KH2 A;  3SGV A;  3SH0 A;  4ONC A;  4CMV A;  4Q9O A;  3TH8 A;  2E9D A;  2VFW A;  1F75 A;  1X08 A;  5KH4 A;  4H2J A;  2D2R A;  4H38 A;  5HXT A;  5HXN A;  4H8E A;  2VG2 A;  4H2O A;  2VG4 A;  3UGS A;  2E9A A;  5HC7 A;  2E98 A;  2DTN A;  4H2M A;  4H3A A;  3WQK A;  4KT8 A;  1X09 A;  3WYJ A;  4CMW A;  5KH5 A;  2VG3 A;  3QAS A;  5HC6 A;  3SGT A;  1JP3 A;  4H3C A;  2E99 A;  4U82 A;  1V7U A;  3WQN A;  5HXP A;  2E9C A;  3WQL A;  2VG0 A;  5CQB A;  5HXO A;  3SGX A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4H2OA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations