4H8EA

Structure of s. aureus undecaprenyl diphosphate synthase in complex with fpp and sulfate
Total Genus 92

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
235
structure length
235
Chain Sequence
LDSSNIPEHIAIIMDGNGRWAKKRKMPRIKGHYEGMQTIKKITRIASDIGVKYLTLYAFSTENWSRPESEVNYIMNLPVNFLKTFLPELIEKNVKVETIGFTDKLPKSTIEAINNAKEKTANNTGLKLIFAINYGGRAELVHSIKNMFDELHQQGLNSDIIDETYINNHLMTKDYPDPELLIRTSGEQRISNFLIWQVSYSEFIFNQKLWPDFDEDELIKCIKIYQSRQRRFGGL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYTI4 (175-178)TI1 (20-23)TIV3 (210-213)S1 (27-31)AH1 (35-42)AH2 (46-67)TI6 (188-191)TI7 (190-193)S2 (71-78)AH3 (86-110)3H1 (81-83)TI2 (78-81)3H2 (120-122)S3 (113-117)AH5 (154-172)TI3 (138-141)TVIII2 (196-199)S4 (145-152)S5 (198-201)AH6 (181-186)TI'1 (208-211)3H3 (228-230)TI10 (214-217)TI8 (212-215)S6 (220-223)TI9 (213-216)AH7 (233-245)O1 (31-33)TIV1 (21-24)TVIII1 (25-28)AH4 (125-137)TI11 (216-219)TI5 (176-179)Updating...
connected with : NaN
molecule tags Transferase/transferase inhibitor
source organism Staphylococcus aureus subsp. aureus
publication title Antibacterial drug leads targeting isoprenoid biosynthesis.
pubmed doi rcsb
molecule keywords Undecaprenyl pyrophosphate synthase
total genus 92
structure length 235
sequence length 235
ec nomenclature ec 2.5.1.31: Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-
pdb deposition date 2012-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01255 Prenyltransf Putative undecaprenyl diphosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1180.10 Alpha Beta 3-Layer(aba) Sandwich Undecaprenyl pyrophosphate synthetase Decaprenyl diphosphate synthase-like 4h8eA00
4CMVA 3SGTA 4U82A 2VG4A 5KH2A 4H38A 4CMXA 5HXOA 2D2RA 2E9AA 3WYJA 5KH5A 4H8EA 1X07A 2E99A 4H2OA 5HC7A 3UGSA 5HC8A 2VFWA 1X09A 2E9DA 5HXNA 3SGXA 2E98A 4Q9OA 3WQKA 3WQNA 2VG1A 5CQJA 2VG0A 4CMWA 2VG3A 1F75A 3QASA 4KT8A 3SH0A 1UEHA 1JP3A 2DTNA 5CQBA 3WQLA 5HXTA 4Q9MA 5HXPA 1V7UA 4H2JA 3TH8A 1X06A 2VG2A 5HXQA 4ONCA 2E9CA 5KH4A 1X08A 4H2MA 3WQMA 3WYIA 4H3AA 5HC6A 3SGVA 4H3CA
chains in the Genus database with same CATH superfamily
4CMVA 3SGTA 4U82A 2VG4A 5KH2A 4H38A 4CMXA 5HXOA 2D2RA 2E9AA 3WYJA 5KH5A 4H8EA 1X07A 2E99A 4H2OA 5HC7A 3UGSA 5HC8A 2VFWA 1X09A 2E9DA 5HXNA 3SGXA 2E98A 4Q9OA 3WQKA 3WQNA 2VG1A 5CQJA 2VG0A 4CMWA 2VG3A 1F75A 3QASA 4KT8A 3SH0A 1UEHA 1JP3A 2DTNA 5CQBA 3WQLA 5HXTA 4Q9MA 5HXPA 1V7UA 4H2JA 3TH8A 1X06A 2VG2A 5HXQA 4ONCA 2E9CA 5KH4A 1X08A 4H2MA 3WQMA 3WYIA 4H3AA 5HC6A 3SGVA 4H3CA
chains in the Genus database with same CATH topology
4CMVA 3SGTA 4U82A 2VG4A 5KH2A 4H38A 4CMXA 5HXOA 2D2RA 2E9AA 3WYJA 5KH5A 4H8EA 1X07A 2E99A 4H2OA 5HC7A 3UGSA 5HC8A 2VFWA 1X09A 2E9DA 5HXNA 3SGXA 2E98A 4Q9OA 3WQKA 3WQNA 2VG1A 5CQJA 2VG0A 4CMWA 2VG3A 1F75A 3QASA 4KT8A 3SH0A 1UEHA 1JP3A 2DTNA 5CQBA 3WQLA 5HXTA 4Q9MA 5HXPA 1V7UA 4H2JA 3TH8A 1X06A 2VG2A 5HXQA 4ONCA 2E9CA 5KH4A 1X08A 4H2MA 3WQMA 3WYIA 4H3AA 5HC6A 3SGVA 4H3CA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4CMV A;  3SGT A;  4U82 A;  2VG4 A;  5KH2 A;  4H38 A;  4CMX A;  5HXO A;  2D2R A;  2E9A A;  3WYJ A;  5KH5 A;  4H8E A;  1X07 A;  2E99 A;  4H2O A;  5HC7 A;  3UGS A;  5HC8 A;  2VFW A;  1X09 A;  2E9D A;  5HXN A;  3SGX A;  2E98 A;  4Q9O A;  3WQK A;  3WQN A;  2VG1 A;  5CQJ A;  2VG0 A;  4CMW A;  2VG3 A;  1F75 A;  3QAS A;  4KT8 A;  3SH0 A;  1UEH A;  1JP3 A;  2DTN A;  5CQB A;  3WQL A;  5HXT A;  4Q9M A;  5HXP A;  1V7U A;  4H2J A;  3TH8 A;  1X06 A;  2VG2 A;  5HXQ A;  4ONC A;  2E9C A;  5KH4 A;  1X08 A;  4H2M A;  3WQM A;  3WYI A;  4H3A A;  5HC6 A;  3SGV A;  4H3C A; 
#chains in the Genus database with same CATH topology
 4CMV A;  3SGT A;  4U82 A;  2VG4 A;  5KH2 A;  4H38 A;  4CMX A;  5HXO A;  2D2R A;  2E9A A;  3WYJ A;  5KH5 A;  4H8E A;  1X07 A;  2E99 A;  4H2O A;  5HC7 A;  3UGS A;  5HC8 A;  2VFW A;  1X09 A;  2E9D A;  5HXN A;  3SGX A;  2E98 A;  4Q9O A;  3WQK A;  3WQN A;  2VG1 A;  5CQJ A;  2VG0 A;  4CMW A;  2VG3 A;  1F75 A;  3QAS A;  4KT8 A;  3SH0 A;  1UEH A;  1JP3 A;  2DTN A;  5CQB A;  3WQL A;  5HXT A;  4Q9M A;  5HXP A;  1V7U A;  4H2J A;  3TH8 A;  1X06 A;  2VG2 A;  5HXQ A;  4ONC A;  2E9C A;  5KH4 A;  1X08 A;  4H2M A;  3WQM A;  3WYI A;  4H3A A;  5HC6 A;  3SGV A;  4H3C A; 
#chains in the Genus database with same CATH homology
 4CMV A;  3SGT A;  4U82 A;  2VG4 A;  5KH2 A;  4H38 A;  4CMX A;  5HXO A;  2D2R A;  2E9A A;  3WYJ A;  5KH5 A;  4H8E A;  1X07 A;  2E99 A;  4H2O A;  5HC7 A;  3UGS A;  5HC8 A;  2VFW A;  1X09 A;  2E9D A;  5HXN A;  3SGX A;  2E98 A;  4Q9O A;  3WQK A;  3WQN A;  2VG1 A;  5CQJ A;  2VG0 A;  4CMW A;  2VG3 A;  1F75 A;  3QAS A;  4KT8 A;  3SH0 A;  1UEH A;  1JP3 A;  2DTN A;  5CQB A;  3WQL A;  5HXT A;  4Q9M A;  5HXP A;  1V7U A;  4H2J A;  3TH8 A;  1X06 A;  2VG2 A;  5HXQ A;  4ONC A;  2E9C A;  5KH4 A;  1X08 A;  4H2M A;  3WQM A;  3WYI A;  4H3A A;  5HC6 A;  3SGV A;  4H3C A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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